Deyasini Chakraborty
@deyasinic.bsky.social
Postdoc at the Novartis BR, Switzerland
PhD, Thomä lab at the Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Interested in chromatin biology.
PhD, Thomä lab at the Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Interested in chromatin biology.
Excited that we got selected for the @cp-molcell.bsky.social cover for the latest issue released today! Congratulations @csandate.bsky.social!
Read the latest issue here: www.cell.com/molecular-ce...
August 7, 2025 at 3:38 PM
Excited that we got selected for the @cp-molcell.bsky.social cover for the latest issue released today! Congratulations @csandate.bsky.social!
Excited to share that my first-author publication from my PhD on the interplay of p53 with cofactors on chromatin is now online in Molecular Cell @cp-molcell.bsky.social : www.cell.com/molecular-ce...
Nucleosomes filter cofactor access to p53 - USP7 can bind whereas E6AP-E6 fails to form a complex.
Nucleosomes filter cofactor access to p53 - USP7 can bind whereas E6AP-E6 fails to form a complex.
Nucleosomes specify co-factor access to p53
Chakraborty, Sandate, et al. report that chromatin-bound p53 interacts with deubiquitinating
enzyme USP7 but not with the E3 ubiquitin ligase E6AP-E6, despite both co-factors
being associated with the...
www.cell.com
August 4, 2025 at 4:29 PM
Excited to share that my first-author publication from my PhD on the interplay of p53 with cofactors on chromatin is now online in Molecular Cell @cp-molcell.bsky.social : www.cell.com/molecular-ce...
Nucleosomes filter cofactor access to p53 - USP7 can bind whereas E6AP-E6 fails to form a complex.
Nucleosomes filter cofactor access to p53 - USP7 can bind whereas E6AP-E6 fails to form a complex.
Reposted by Deyasini Chakraborty
Our cells pack DNA into tiny bundles that hide important parts. Researchers at the FMI and EPFL found this packing affects how the cancer-fighting protein p53 works, revealing new insights into cancer. www.fmi.ch/news-events/...
How DNA packaging controls the “genome’s guardian”
Our cells tightly pack DNA into structures called nucleosomes, which protect DNA but also hide important sites. The key cancer-fighting protein p53 can still access these hidden sites, especially at n...
www.fmi.ch
July 31, 2025 at 8:59 AM
Our cells pack DNA into tiny bundles that hide important parts. Researchers at the FMI and EPFL found this packing affects how the cancer-fighting protein p53 works, revealing new insights into cancer. www.fmi.ch/news-events/...
Reposted by Deyasini Chakraborty
Congratulations to Dr. Deyasini Chakraborty on defending her PhD thesis this week! 🥳🎓 Her research reveals how nucleosomes—structures of DNA wrapped around proteins—control the access of specific molecules to p53, a protein that helps regulate cell growth and prevent cancer.
February 26, 2025 at 2:02 PM
Congratulations to Dr. Deyasini Chakraborty on defending her PhD thesis this week! 🥳🎓 Her research reveals how nucleosomes—structures of DNA wrapped around proteins—control the access of specific molecules to p53, a protein that helps regulate cell growth and prevent cancer.