Denis Chaimow
denischaimow.bsky.social
Denis Chaimow
@denischaimow.bsky.social
Reposted by Denis Chaimow
Vascular draining confounds laminar decoding in fMRI https://www.biorxiv.org/content/10.1101/2025.08.26.672278v1
August 30, 2025 at 10:15 AM
Reposted by Denis Chaimow
What started as a journal club on layer decoding turned into a project thanks to @karolisdegutis.bsky.social. Our preprint challenges a widespread assumption in the field: MVPA is not immune to vascular confounds in laminar GE-BOLD decoding, as shown using a mechanistic laminar response model.
Happy to see this out: our new preprint shows that laminar GE-BOLD fMRI decoding isn’t immune to vascular draining biases. Simulations reveal false positives due to multivariate signal spread across layers, but oversampling + deconvolution can (sometimes) improve specificity.
August 30, 2025 at 2:58 PM
Reposted by Denis Chaimow
Happy to see this out: our new preprint shows that laminar GE-BOLD fMRI decoding isn’t immune to vascular draining biases. Simulations reveal false positives due to multivariate signal spread across layers, but oversampling + deconvolution can (sometimes) improve specificity.
August 30, 2025 at 2:28 PM
Reposted by Denis Chaimow
I’m happy to share that our manuscript on the cortical depth-dependency of the GE- and SE-BOLD point spread function at 7 Tesla is now available on bioRxiv!

www.biorxiv.org/content/10.1...
Spatial specificity of the functional gradient echo and spin echo BOLD signal across cortical depth at 7 T
Functional magnetic resonance imaging (fMRI) at high magnetic field strengths (≥ 7 T) is a promising technique to study the functioning of the human brain at the spatial scale of cortical columns and ...
www.biorxiv.org
August 1, 2025 at 1:38 PM
Reposted by Denis Chaimow
Very happy to share our work on the neural dynamics of visual working memory maintenance during sensory distraction; now out as a VOR on eLIife: elifesciences.org/articles/99290
Neural dynamics of visual working memory representation during sensory distraction
Dynamic shifts in neural coding combined with stable population subspaces enable visual areas to concurrently represent sensory inputs and working memory without mutual interference.
elifesciences.org
June 24, 2025 at 11:01 PM
Reposted by Denis Chaimow
New paper in Imaging Neuroscience by Fakhereh Movahedian Attar, Nikolaus Weiskopf, et al:

Short association fibres form topographic sheets in the human V1–V2 processing stream

doi.org/10.1162/imag...
March 17, 2025 at 6:27 AM
Excited to share our latest preprint: "Challenges in replicating layer-specificity of working memory processes in the human prefrontal cortex.”, where we attempted to replicate layer-specific fMRI findings in the human dlPFC during a working memory task.
www.biorxiv.org/content/10.1...
Challenges in replicating layer-specificity of working memory processes in human dlPFC
Although working memory reliably activates the dorsolateral prefrontal cortex (dlPFC), the functional significance of its distinct cytoarchitectonic layers is not well understood in humans. A recent f...
www.biorxiv.org
February 20, 2025 at 2:20 PM
Reposted by Denis Chaimow
Challenges in replicating layer-specificity of working memory processes in human dlPFC https://www.biorxiv.org/content/10.1101/2025.01.31.635930v1
February 4, 2025 at 11:15 AM