Doron Betel
dbetel.bsky.social
Doron Betel
@dbetel.bsky.social
Computational Biologist at Weill Cornell, NYC.
https://icb.med.cornell.edu/faculty/betel/lab/betelab/
Big congratulations to my student Dr. Jonathan Rub who did an amazing job at his thesis defense. Presenting a new cross-species single cell integration deep learning algorithm (doi.org/10.1101/2024...). Big thanks to his co-mentor Tuomas Tammela and committee members Christina Leslie & Ping Chi.
May 7, 2025 at 4:13 PM
Our recent paper in #AgingCell with @studerl.bsky.social where we identify age inducing compounds for improved modeling of neurodegeneration.

Big congratulations to Chao Zhang (now PI at Boston University) and Nathalie Saurat (now PI at Monash University) who led this work.
doi.org/10.1111/acel...
Identifying Age‐Modulating Compounds Using a Novel Computational Framework for Evaluating Transcriptional Age
RNAge is a transcriptional based computational approach to measure changes in cellular age upon experimental manipulation. In silico screening of a database of transcriptional changes from drug pertu....
doi.org
May 1, 2025 at 5:25 PM
Reposted by Doron Betel
The only way forward, that I can see, requires both courage and collective action. If we’re not going to fight for our students and our scholarship, then what the hell are we doing anyway?
University presidents, the time is now! Unshackle the general counsel's office! File all the lawsuits! Release the faculty upon the op-ed sections! Write to your alumni, parents, and donors! You have nothing to lose but a tiny percentage of your enormous endowments... www.nytimes.com/2025/04/08/u...
Trump Officials Freeze $1 Billion for Cornell and $790 Million for Northwestern
The funding pause amid civil rights investigations into both universities sharply escalates the Trump administration’s campaign against elite colleges.
www.nytimes.com
April 9, 2025 at 1:02 AM
I'm very excited to share our latest preprint from our very talented student Jonathan Rub and close collaborators Tuomas Tammela and Jason Chan (from @mskcancerceter.bsky.social). A variational autoencoder framework for single cell cross-species integration. doi.org/10.1101/2024...
December 23, 2024 at 5:00 PM
Reposted by Doron Betel
New in @natureportfolio.bsky.social from the Tuomas Tammela Lab: how aging suppresses tumorigenesis and stemness in the lung by promoting functional iron insufficiency in the alveolar epithelium. Interestingly, this renders aged cells resistant to ferroptosis. #OncSky www.nature.com/articles/s41...
Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis - Nature
Studies using mouse models of lung adenocarcinoma identify an association between age, iron homeostasis and tumour initiation potential that involves NUPR1 and lipocalin-2.
www.nature.com
December 4, 2024 at 6:23 PM