Davide Sala
@davsal1.bsky.social
Computational chemist and structural biologist
www.nature.com/articles/s41...
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Run this and go on vacation?
The Virtual Lab of AI agents designs new SARS-CoV-2 nanobodies - Nature
Nature - The Virtual Lab of AI agents designs new SARS-CoV-2 nanobodies
www.nature.com
July 29, 2025 at 6:58 PM
www.nature.com/articles/s41...
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Run this and go on vacation?
Cool! A molecular glue mimicking a cancer mutation enables gain-of-function degradation. www.nature.com/articles/s41...
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations - Nature
We show that gain-of-function cancer mutations in the KBTBD4 E3 ligase promote neodegradation of substrates via a shape-complementarity-based mechanism, which converges with the mechanism of action of...
www.nature.com
February 19, 2025 at 10:15 AM
Cool! A molecular glue mimicking a cancer mutation enables gain-of-function degradation. www.nature.com/articles/s41...