David Lougheed
@davidlougheed.bsky.social
Bioinformatics software developer at the Canadian Centre for Computational Genomics, Montreal. https://dlougheed.com
Reposted by David Lougheed
Long-read sequencing reveals telomere inheritance patterns from human trios https://www.biorxiv.org/content/10.1101/2025.10.07.680721v1
October 7, 2025 at 11:32 PM
Long-read sequencing reveals telomere inheritance patterns from human trios https://www.biorxiv.org/content/10.1101/2025.10.07.680721v1
I’m happy to (finally!) share STRkit, a short tandem repeat genotyping tool for long reads that I've developed in @guilbourque.bsky.social's group over the past few years. Here we describe STRkit & demonstrate state-of-the-art performance in some benchmarks – long reads are great for resolving STRs!
STRkit: precise, read-level genotyping of short tandem repeats using long reads and single-nucleotide variation https://www.biorxiv.org/content/10.1101/2025.03.25.645269v1
March 29, 2025 at 1:01 PM
I’m happy to (finally!) share STRkit, a short tandem repeat genotyping tool for long reads that I've developed in @guilbourque.bsky.social's group over the past few years. Here we describe STRkit & demonstrate state-of-the-art performance in some benchmarks – long reads are great for resolving STRs!