Daniele Bertoglio
@danielebertoglio.bsky.social
TT Assistant Professor @ Bio-Imaging Lab
@UAntwerpen. Investigating the 🧠 in health and disease using 🐭 imaging. #MRI 🧲 #PET ☢️ #Biomarker #newPI
@UAntwerpen. Investigating the 🧠 in health and disease using 🐭 imaging. #MRI 🧲 #PET ☢️ #Biomarker #newPI
How can we measure mutant Huntingtin #aggregates in the 🧠 brain?
We investigated a novel ☢️ #PET imaging radioligand, [18F]CHDI-385 to track 📈 non-invasively the mHTT aggregates in the brain 🧠 of a mouse 🐭 model of #Huntington’s Disease.
#openaccess article published in JNM: 👉 lnkd.in/eK68-UbU
We investigated a novel ☢️ #PET imaging radioligand, [18F]CHDI-385 to track 📈 non-invasively the mHTT aggregates in the brain 🧠 of a mouse 🐭 model of #Huntington’s Disease.
#openaccess article published in JNM: 👉 lnkd.in/eK68-UbU
In Vivo PET Imaging of [18F]CHDI-385, a Radioligand for Mutant Huntingtin Aggregates in a Mouse Model of Huntington Disease
Aggregation of mutant huntingtin (mHTT) is a neurologic hallmark of Huntington disease (HD), a neurodegenerative disorder caused by the expansion of a cytosine–adenine–guanine repeat tract in the hunt...
jnm.snmjournals.org
November 14, 2025 at 10:48 AM
How can we measure mutant Huntingtin #aggregates in the 🧠 brain?
We investigated a novel ☢️ #PET imaging radioligand, [18F]CHDI-385 to track 📈 non-invasively the mHTT aggregates in the brain 🧠 of a mouse 🐭 model of #Huntington’s Disease.
#openaccess article published in JNM: 👉 lnkd.in/eK68-UbU
We investigated a novel ☢️ #PET imaging radioligand, [18F]CHDI-385 to track 📈 non-invasively the mHTT aggregates in the brain 🧠 of a mouse 🐭 model of #Huntington’s Disease.
#openaccess article published in JNM: 👉 lnkd.in/eK68-UbU
Reposted by Daniele Bertoglio
New HD focused article leveraging multi-modal imaging from our long-standing collaboration with @danielebertoglio.bsky.social and colleagues! www.sciencedirect.com/science/arti...
Longitudinal investigation of structural and resting-state effective connectivity alterations in a non-human primate model of Huntington's disease
Huntington's disease (HD) is a genetic neurodegenerative disorder caused by expanded CAG repeats in the huntingtin gene which produce a mutant hunting…
www.sciencedirect.com
October 24, 2025 at 12:12 PM
New HD focused article leveraging multi-modal imaging from our long-standing collaboration with @danielebertoglio.bsky.social and colleagues! www.sciencedirect.com/science/arti...
🎉 Very proud of our PhD student Marion Decrop for securing a PhD Fellowship from FWO @fwovlaanderen.bsky.social! 👏 🎉
Using pharmacological fMRI 🧲, this fellowship will allow us to understand how the dopaminergic system is functionally impacted in Huntington's disease 🧠
Using pharmacological fMRI 🧲, this fellowship will allow us to understand how the dopaminergic system is functionally impacted in Huntington's disease 🧠
October 9, 2025 at 7:59 AM
🎉 Very proud of our PhD student Marion Decrop for securing a PhD Fellowship from FWO @fwovlaanderen.bsky.social! 👏 🎉
Using pharmacological fMRI 🧲, this fellowship will allow us to understand how the dopaminergic system is functionally impacted in Huntington's disease 🧠
Using pharmacological fMRI 🧲, this fellowship will allow us to understand how the dopaminergic system is functionally impacted in Huntington's disease 🧠
Reposted by Daniele Bertoglio
New pre-print from an incredibly productive collaboration between my lab and the team led by @danielebertoglio.bsky.social
Longitudinal Investigation of Structural and Resting-State Effective Connectivity Alterations in a Non-Human Primate Model of Huntington's Disease https://www.biorxiv.org/content/10.1101/2025.07.18.665554v1
July 24, 2025 at 12:25 AM
New pre-print from an incredibly productive collaboration between my lab and the team led by @danielebertoglio.bsky.social
Great couple of inspiring days at the #WingsforLife scientific meeting in Salzburg! 🇦🇹
Really pleased to share the update of our project with the🥼community & very thankful for the #funding support on the development of in vivo imaging ☢️ 🧲 #biomakers for spinal cord injury! 🐁🔬
Really pleased to share the update of our project with the🥼community & very thankful for the #funding support on the development of in vivo imaging ☢️ 🧲 #biomakers for spinal cord injury! 🐁🔬
May 15, 2025 at 4:52 PM
Great couple of inspiring days at the #WingsforLife scientific meeting in Salzburg! 🇦🇹
Really pleased to share the update of our project with the🥼community & very thankful for the #funding support on the development of in vivo imaging ☢️ 🧲 #biomakers for spinal cord injury! 🐁🔬
Really pleased to share the update of our project with the🥼community & very thankful for the #funding support on the development of in vivo imaging ☢️ 🧲 #biomakers for spinal cord injury! 🐁🔬
Running for those who can't 👟
#WingsforlifeWorldRun
#WingsforlifeWorldRun
May 4, 2025 at 1:52 PM
Running for those who can't 👟
#WingsforlifeWorldRun
#WingsforlifeWorldRun
Can we identify biomarkers responsive to mHTT lowering?
In this new study, we investigated 💧 #CSF and ☢️ #PET biomarkers that could be used non-invasively to track 📈 the temporal response to #mHTT modulation in mice 🐭.
#openaccess article: 👉 lnkd.in/eqTirauF
In this new study, we investigated 💧 #CSF and ☢️ #PET biomarkers that could be used non-invasively to track 📈 the temporal response to #mHTT modulation in mice 🐭.
#openaccess article: 👉 lnkd.in/eqTirauF
April 16, 2025 at 10:22 AM
Can we identify biomarkers responsive to mHTT lowering?
In this new study, we investigated 💧 #CSF and ☢️ #PET biomarkers that could be used non-invasively to track 📈 the temporal response to #mHTT modulation in mice 🐭.
#openaccess article: 👉 lnkd.in/eqTirauF
In this new study, we investigated 💧 #CSF and ☢️ #PET biomarkers that could be used non-invasively to track 📈 the temporal response to #mHTT modulation in mice 🐭.
#openaccess article: 👉 lnkd.in/eqTirauF
How can we quantify 🧠 SV2A PET imaging noninvasively in rats 🐁?
In this new study led by Lori Berckmans, we investigated non-invasive quantification methods for PET imaging with [18F]SynVesT-1 ☢️ as an alternative to blood 🩸 sampling for arterial input function.
link.springer.com/article/10.1...
In this new study led by Lori Berckmans, we investigated non-invasive quantification methods for PET imaging with [18F]SynVesT-1 ☢️ as an alternative to blood 🩸 sampling for arterial input function.
link.springer.com/article/10.1...
April 2, 2025 at 6:38 AM
How can we quantify 🧠 SV2A PET imaging noninvasively in rats 🐁?
In this new study led by Lori Berckmans, we investigated non-invasive quantification methods for PET imaging with [18F]SynVesT-1 ☢️ as an alternative to blood 🩸 sampling for arterial input function.
link.springer.com/article/10.1...
In this new study led by Lori Berckmans, we investigated non-invasive quantification methods for PET imaging with [18F]SynVesT-1 ☢️ as an alternative to blood 🩸 sampling for arterial input function.
link.springer.com/article/10.1...
A very fruitful edition of our group's MaRBEL meeting of the 🇧🇪 Belgian 🧲 MR Research Community!
- 🏆Best Scientific Poster Award for Monica van den Berg 👏
- 🏆Best Protocol Poster Award for Marion Decrop 👏
- 🗨️ Invited talk by Joëlle van Rijswijk 👏
- 🗨️ Selected talk by Claudia Schrauwen 👏
- 🏆Best Scientific Poster Award for Monica van den Berg 👏
- 🏆Best Protocol Poster Award for Marion Decrop 👏
- 🗨️ Invited talk by Joëlle van Rijswijk 👏
- 🗨️ Selected talk by Claudia Schrauwen 👏
February 25, 2025 at 1:56 PM
A very fruitful edition of our group's MaRBEL meeting of the 🇧🇪 Belgian 🧲 MR Research Community!
- 🏆Best Scientific Poster Award for Monica van den Berg 👏
- 🏆Best Protocol Poster Award for Marion Decrop 👏
- 🗨️ Invited talk by Joëlle van Rijswijk 👏
- 🗨️ Selected talk by Claudia Schrauwen 👏
- 🏆Best Scientific Poster Award for Monica van den Berg 👏
- 🏆Best Protocol Poster Award for Marion Decrop 👏
- 🗨️ Invited talk by Joëlle van Rijswijk 👏
- 🗨️ Selected talk by Claudia Schrauwen 👏
New paper out! 👏🥳
Our work by Judith Van Rooij explored how caloric restriction and resveratrol 💊supplementation affect brain 🧠 function as measured with rsfMRI 🧲 and whether these effects differ by sex in rats 🐁.
www.frontiersin.org/journals/nut...
Our work by Judith Van Rooij explored how caloric restriction and resveratrol 💊supplementation affect brain 🧠 function as measured with rsfMRI 🧲 and whether these effects differ by sex in rats 🐁.
www.frontiersin.org/journals/nut...
Frontiers | Short-term caloric restriction or resveratrol supplementation alters large-scale brain network connectivity in male and female rats
www.frontiersin.org
February 11, 2025 at 8:04 AM
New paper out! 👏🥳
Our work by Judith Van Rooij explored how caloric restriction and resveratrol 💊supplementation affect brain 🧠 function as measured with rsfMRI 🧲 and whether these effects differ by sex in rats 🐁.
www.frontiersin.org/journals/nut...
Our work by Judith Van Rooij explored how caloric restriction and resveratrol 💊supplementation affect brain 🧠 function as measured with rsfMRI 🧲 and whether these effects differ by sex in rats 🐁.
www.frontiersin.org/journals/nut...