Current Medical Science
@currentmedscience.bsky.social
Current Medical Science is a peer-reviewed journal publishing original, innovative & influential insightful reviews, comments, & special topic articles across diverse medical disciplines, including biomedicine, public health, and related fields.
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Cite Score Alert!
We’re proud to announce that our 2024 #CiteScore is 3.8!
We appreciate our authors, reviewers, readers, and editorial team.
Submit your research to @currentmedscience.bsky.social & be part of our growing journey!
link.springer.com/journal/11596/
#ScienceSky #medsky #academicsky
We’re proud to announce that our 2024 #CiteScore is 3.8!
We appreciate our authors, reviewers, readers, and editorial team.
Submit your research to @currentmedscience.bsky.social & be part of our growing journey!
link.springer.com/journal/11596/
#ScienceSky #medsky #academicsky
This review summarizes ancient Chinese ideas & health policies on #Epidemic prevention & control, offering historical insights to inspire contemporary efforts in the prevention & control of #InfectiousDisease, especially in medically challenging regions.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 27, 2025 at 10:50 AM
This review summarizes ancient Chinese ideas & health policies on #Epidemic prevention & control, offering historical insights to inspire contemporary efforts in the prevention & control of #InfectiousDisease, especially in medically challenging regions.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Researchers summarize how iron-dependent #LipidPeroxidation drives #ferroptosis, outline the metabolic and signaling pathways regulating ferroptosis in #BladderCancer, and highlight emerging ferroptosis inducers and combination strategies.
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
December 26, 2025 at 12:30 PM
Researchers summarize how iron-dependent #LipidPeroxidation drives #ferroptosis, outline the metabolic and signaling pathways regulating ferroptosis in #BladderCancer, and highlight emerging ferroptosis inducers and combination strategies.
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
An overview of the functions of #CopperHomeostasis & #Cuproptosis in the nervous system and the pathogenesis of #NeurodegenerativeDiseases, the underlying mechanisms, and insights into cuproptosis-based targeted treatment of neurodegenerative diseases.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 26, 2025 at 1:45 AM
An overview of the functions of #CopperHomeostasis & #Cuproptosis in the nervous system and the pathogenesis of #NeurodegenerativeDiseases, the underlying mechanisms, and insights into cuproptosis-based targeted treatment of neurodegenerative diseases.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This review highlights emerging cellular landscapes in #atherosclerosis and discusses #StemCell and #nanoparticle therapies, emphasizing the need for multi‑target strategies to bridge mechanistic insights with clinical translation. #ferroptosis
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
December 25, 2025 at 9:30 AM
This review highlights emerging cellular landscapes in #atherosclerosis and discusses #StemCell and #nanoparticle therapies, emphasizing the need for multi‑target strategies to bridge mechanistic insights with clinical translation. #ferroptosis
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
A systematic two-sample #MendelianRandomization analysis using SNPs identified from #GWAS revealed a possible causal relationship between specific #GutMicrobiota characteristics and vitamin A, B12 and D deficiencies.
Read this: doi.org/10.1007/s115...
Read this: doi.org/10.1007/s115...
December 24, 2025 at 1:20 PM
A systematic two-sample #MendelianRandomization analysis using SNPs identified from #GWAS revealed a possible causal relationship between specific #GutMicrobiota characteristics and vitamin A, B12 and D deficiencies.
Read this: doi.org/10.1007/s115...
Read this: doi.org/10.1007/s115...
Scientists describe 13 cases of #OcularToxoplasmosis in China, identifying #retinochoroiditis as the main form and showing that timely diagnosis and appropriate treatment improve visual outcomes and reduce misdiagnosis and recurrence risk.
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
December 24, 2025 at 2:45 AM
Scientists describe 13 cases of #OcularToxoplasmosis in China, identifying #retinochoroiditis as the main form and showing that timely diagnosis and appropriate treatment improve visual outcomes and reduce misdiagnosis and recurrence risk.
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
Data from multiple sources provide insights into the safety profile of #Sacituzumab #Govitecan (SG), identifying common hematologic toxicities and unexpected #AdverseEffects, underscoring the need for critical clinical monitoring & management.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 23, 2025 at 5:45 AM
Data from multiple sources provide insights into the safety profile of #Sacituzumab #Govitecan (SG), identifying common hematologic toxicities and unexpected #AdverseEffects, underscoring the need for critical clinical monitoring & management.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
#Safranal protects against membranous #glomerulonephritis in rats by reducing #proteinuria, #inflammation, and #podocyte injury; restoring #nephrin/podocin levels; and suppressing NF-κB-driven renal inflammation via Sirt1 pathway activation.
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
December 22, 2025 at 11:55 AM
#Safranal protects against membranous #glomerulonephritis in rats by reducing #proteinuria, #inflammation, and #podocyte injury; restoring #nephrin/podocin levels; and suppressing NF-κB-driven renal inflammation via Sirt1 pathway activation.
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
This study shows that combining third-generation #EGFR-TKIs with #Radiotherapy significantly extends progression-free survival in advanced EGFR-mutant #NSCLC patients, with acceptable safety and low toxicity. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 21, 2025 at 6:30 AM
This study shows that combining third-generation #EGFR-TKIs with #Radiotherapy significantly extends progression-free survival in advanced EGFR-mutant #NSCLC patients, with acceptable safety and low toxicity. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Scientists identify #NOX4 as a key therapeutic target in #ColorectalCancer, showing that its interaction with #G6PD boosts the #PentosePhosphatePathway, enhances #ROS clearance, suppresses #ferroptosis, and promotes #tumor cell survival.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 20, 2025 at 10:30 AM
Scientists identify #NOX4 as a key therapeutic target in #ColorectalCancer, showing that its interaction with #G6PD boosts the #PentosePhosphatePathway, enhances #ROS clearance, suppresses #ferroptosis, and promotes #tumor cell survival.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Elevated NCAPD3 expression strongly correlates with #HepatocellularCarcinoma #Metastasis, while its inhibition mitigates HCC cell growth and metastatic potential by suppressing the PI3K–AKT signalling pathway.
Link to full-text: doi.org/10.1007/s115...
Link to full-text: doi.org/10.1007/s115...
December 19, 2025 at 12:35 PM
Elevated NCAPD3 expression strongly correlates with #HepatocellularCarcinoma #Metastasis, while its inhibition mitigates HCC cell growth and metastatic potential by suppressing the PI3K–AKT signalling pathway.
Link to full-text: doi.org/10.1007/s115...
Link to full-text: doi.org/10.1007/s115...
Simple #SyringeFiltration of large #ExtracellularVesicles removes impurity particles after #ultracentrifugation, reducing variability in #DynamicLightScattering measurements and improving the precision & reliability of EV size distribution analysis.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 19, 2025 at 1:45 AM
Simple #SyringeFiltration of large #ExtracellularVesicles removes impurity particles after #ultracentrifugation, reducing variability in #DynamicLightScattering measurements and improving the precision & reliability of EV size distribution analysis.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Comprehensive profiling of #Exosome-derived serum metabolites in #SystemicLupusErythematosus patients identified key metabolites, their diagnostic & discriminative performance, and their association with disease progression.
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
December 18, 2025 at 11:45 AM
Comprehensive profiling of #Exosome-derived serum metabolites in #SystemicLupusErythematosus patients identified key metabolites, their diagnostic & discriminative performance, and their association with disease progression.
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
Development of a #DeepNeuralNetwork that significantly outperformed multiple #MachineLearning and #DeepLearning models in diagnosing #ParkinsonsDisease from handwritten spiral and wave images, achieving higher accuracy, sensitivity, and specificity.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 18, 2025 at 6:19 AM
Development of a #DeepNeuralNetwork that significantly outperformed multiple #MachineLearning and #DeepLearning models in diagnosing #ParkinsonsDisease from handwritten spiral and wave images, achieving higher accuracy, sensitivity, and specificity.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Demonstrating the first multimodal #3DImaging atlas of a rat BCI, fusing micro-CT & MRI data of the brain, arteries, & device with #MixedReality for interactive visualization, offering an objective reference for studying BCI. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 17, 2025 at 1:45 AM
Demonstrating the first multimodal #3DImaging atlas of a rat BCI, fusing micro-CT & MRI data of the brain, arteries, & device with #MixedReality for interactive visualization, offering an objective reference for studying BCI. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Non‑severe #AcquiredAplasticAnemia patients show persistently reduced circulating #Tregs even after #ImmunosuppressiveTherapy, highlighting that combining relative and absolute Treg counts may improve distinction of #BoneMarrow failure syndromes.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 16, 2025 at 9:30 AM
Non‑severe #AcquiredAplasticAnemia patients show persistently reduced circulating #Tregs even after #ImmunosuppressiveTherapy, highlighting that combining relative and absolute Treg counts may improve distinction of #BoneMarrow failure syndromes.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Using CT-DCG, this study provides essential anatomical insights into the spatial relationship between the LS & middle turbinate axilla in Chinese patients with nasolacrimal duct obstruction, showing that it varies by gender & disease type. #ENT #MedicalResearch
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 15, 2025 at 12:01 PM
Using CT-DCG, this study provides essential anatomical insights into the spatial relationship between the LS & middle turbinate axilla in Chinese patients with nasolacrimal duct obstruction, showing that it varies by gender & disease type. #ENT #MedicalResearch
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Scientists demonstrate that #electroacupuncture at ST36 and LR3 enhances #gastrointestinalmotility in #FunctionalDyspepsia rats by activating the GDNF/GFRα1/PI3K/Akt pathway and thereby improving #gastrointestinal function and alleviating FD symptoms.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 14, 2025 at 2:13 AM
Scientists demonstrate that #electroacupuncture at ST36 and LR3 enhances #gastrointestinalmotility in #FunctionalDyspepsia rats by activating the GDNF/GFRα1/PI3K/Akt pathway and thereby improving #gastrointestinal function and alleviating FD symptoms.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This study shows that yinchenhao decoction + praziquantel mitigates schistosomiasis-associated hepatic granulomatous #Iinflammation and #Fibrosis by inhibiting hepatic #Apoptosis & #ERstress in a #Schistosomiasis mouse model. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 13, 2025 at 10:15 AM
This study shows that yinchenhao decoction + praziquantel mitigates schistosomiasis-associated hepatic granulomatous #Iinflammation and #Fibrosis by inhibiting hepatic #Apoptosis & #ERstress in a #Schistosomiasis mouse model. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Researchers demonstrate that NEP1-40 promotes hippocampal #NeuralStemCell differentiation into #neurons and reduces #astrocyte proliferation and #neuronalapoptosis, leading to improved #cognitive and behavioral symptoms in #schizophrenia mouse models.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 12, 2025 at 1:45 PM
Researchers demonstrate that NEP1-40 promotes hippocampal #NeuralStemCell differentiation into #neurons and reduces #astrocyte proliferation and #neuronalapoptosis, leading to improved #cognitive and behavioral symptoms in #schizophrenia mouse models.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
On this #UniversalHealthCoverageDay, @cmedicalscience reaffirms its commitment to a future where everyone has access to quality #healthcare—when they need it, where they need it, and without financial burden.
Healthcare is a #FundamentalHumanRight
Healthcare is a #FundamentalHumanRight
December 12, 2025 at 9:01 AM
On this #UniversalHealthCoverageDay, @cmedicalscience reaffirms its commitment to a future where everyone has access to quality #healthcare—when they need it, where they need it, and without financial burden.
Healthcare is a #FundamentalHumanRight
Healthcare is a #FundamentalHumanRight
Chop deficiency exacerbates #Inflammation, tissue injury, macrophage infiltration and bladder epithelial apoptosis in #cyclophosphamide-induced overactive bladder (OAB) by inhibiting #ERstress.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 12, 2025 at 2:00 AM
Chop deficiency exacerbates #Inflammation, tissue injury, macrophage infiltration and bladder epithelial apoptosis in #cyclophosphamide-induced overactive bladder (OAB) by inhibiting #ERstress.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Physiological reconstruction for severe #PelvicOrganProlapse—restoring #PelvicFloor support and #vaginal axis via mesh repair and #MuscleReconstruction—delivers significant objective and subjective improvements with minimal complication rates.
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
December 11, 2025 at 12:30 PM
Physiological reconstruction for severe #PelvicOrganProlapse—restoring #PelvicFloor support and #vaginal axis via mesh repair and #MuscleReconstruction—delivers significant objective and subjective improvements with minimal complication rates.
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
Long maternal sleep duration may exert a direct & prolonged negative impact on head circumference & fetal biparietal diameter, underscoring the importance of proper sleep duration during pregnancy. #medsky
#MaternalHealth #Pregnancy
Current Medical Science: doi.org/10.1007/s115...
#MaternalHealth #Pregnancy
Current Medical Science: doi.org/10.1007/s115...
December 10, 2025 at 12:02 PM
Long maternal sleep duration may exert a direct & prolonged negative impact on head circumference & fetal biparietal diameter, underscoring the importance of proper sleep duration during pregnancy. #medsky
#MaternalHealth #Pregnancy
Current Medical Science: doi.org/10.1007/s115...
#MaternalHealth #Pregnancy
Current Medical Science: doi.org/10.1007/s115...
A novel 26-plex #ShortTandemRepeat #GenotypingAssay enables accurate identification of CHM without #maternal tissue by integrating multi-chromosomal STRs with p57 #immunohistochemistry, enhancing diagnostic reliability and supporting #GeneticCounseling.#Genetics
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 10, 2025 at 2:15 AM
A novel 26-plex #ShortTandemRepeat #GenotypingAssay enables accurate identification of CHM without #maternal tissue by integrating multi-chromosomal STRs with p57 #immunohistochemistry, enhancing diagnostic reliability and supporting #GeneticCounseling.#Genetics
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...