Current Medical Science
@currentmedscience.bsky.social
Current Medical Science is a peer-reviewed journal publishing original, innovative & influential insightful reviews, comments, & special topic articles across diverse medical disciplines, including biomedicine, public health, and related fields.
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Cite Score Alert!
We’re proud to announce that our 2024 #CiteScore is 3.8!
We appreciate our authors, reviewers, readers, and editorial team.
Submit your research to @currentmedscience.bsky.social & be part of our growing journey!
link.springer.com/journal/11596/
#ScienceSky #medsky #academicsky
We’re proud to announce that our 2024 #CiteScore is 3.8!
We appreciate our authors, reviewers, readers, and editorial team.
Submit your research to @currentmedscience.bsky.social & be part of our growing journey!
link.springer.com/journal/11596/
#ScienceSky #medsky #academicsky
Lower #hemoglobin, albumin, and platelet counts plus elevated IL-1β were identified as independent risk factors for poor prognosis in #PediatricSepsis, highlighting the need for early monitoring and timely intervention. #Inflammation
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 12, 2026 at 1:10 PM
Lower #hemoglobin, albumin, and platelet counts plus elevated IL-1β were identified as independent risk factors for poor prognosis in #PediatricSepsis, highlighting the need for early monitoring and timely intervention. #Inflammation
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This study identifies advanced maternal age, third-trimester gestation, and positive FAST scans as critical predictors of adverse pregnancy outcomes post-trauma, stressing the need to monitor these indicators to prevent such outcomes.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 11, 2026 at 2:30 PM
This study identifies advanced maternal age, third-trimester gestation, and positive FAST scans as critical predictors of adverse pregnancy outcomes post-trauma, stressing the need to monitor these indicators to prevent such outcomes.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
LPS-induced #UterineInflammation activates TLR4/NF-κB signaling, elevating #ProinflammatoryCytokines while suppressing Cx43 and #OxytocinReceptor expression, leading to myometrial dysfunction and #UterineAtony relevant to #PostpartumHemorrhage.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 11, 2026 at 6:00 AM
LPS-induced #UterineInflammation activates TLR4/NF-κB signaling, elevating #ProinflammatoryCytokines while suppressing Cx43 and #OxytocinReceptor expression, leading to myometrial dysfunction and #UterineAtony relevant to #PostpartumHemorrhage.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This study establishes CDC20 as a #TherapeuticTarget in #EndometrialCarcinoma, showing that its inhibitor, #Apcin, suppresses proliferation and induces #Apoptosis & cell cycle arrest, by activating the BBC3/caspase-3 pathway & enhancing p21 expression.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 10, 2026 at 2:02 PM
This study establishes CDC20 as a #TherapeuticTarget in #EndometrialCarcinoma, showing that its inhibitor, #Apcin, suppresses proliferation and induces #Apoptosis & cell cycle arrest, by activating the BBC3/caspase-3 pathway & enhancing p21 expression.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Circ_0012152 is identified as an independent adverse #PrognosticFactor in #AcuteMyeloidLeukemia, with its upregulation promoting #leukemic cell growth and survival by sponging miR-652-3p to derepress #SOX4 and drive AML progression.
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
February 9, 2026 at 1:15 PM
Circ_0012152 is identified as an independent adverse #PrognosticFactor in #AcuteMyeloidLeukemia, with its upregulation promoting #leukemic cell growth and survival by sponging miR-652-3p to derepress #SOX4 and drive AML progression.
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
A randomized clinical study demonstrates that the Jianpi Shengxue tablet effectively treats #RenalAnemia by significantly improving red blood cell counts, iron metabolism markers, and systemic symptoms compared to standard #IronTherapy. #Medsky
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
February 8, 2026 at 12:01 PM
A randomized clinical study demonstrates that the Jianpi Shengxue tablet effectively treats #RenalAnemia by significantly improving red blood cell counts, iron metabolism markers, and systemic symptoms compared to standard #IronTherapy. #Medsky
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
TRPC6 knockout alleviates #RenalFibrosis by reducing fibrotic markers, #apoptosis, and #inflammation, while downregulating the PI3K/AKT/GSK3β pathway—supporting TRPC6 inhibition as a promising therapeutic strategy for #ChronicKidneyDisease.
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
February 7, 2026 at 11:01 AM
TRPC6 knockout alleviates #RenalFibrosis by reducing fibrotic markers, #apoptosis, and #inflammation, while downregulating the PI3K/AKT/GSK3β pathway—supporting TRPC6 inhibition as a promising therapeutic strategy for #ChronicKidneyDisease.
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
#Ginsenoside Rb1 protects BMECs from #Ischemia-reperfusion injury by regulating #Autophagy, #Apoptosis, and #OxidativeStress via SQSTM1/p62, ATG5, and HIF-1α, highlighting these as potential #TherapeuticTargets for #IschemicStroke.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 6, 2026 at 2:01 PM
#Ginsenoside Rb1 protects BMECs from #Ischemia-reperfusion injury by regulating #Autophagy, #Apoptosis, and #OxidativeStress via SQSTM1/p62, ATG5, and HIF-1α, highlighting these as potential #TherapeuticTargets for #IschemicStroke.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Adding leukocyte- and platelet-rich fibrin to standard care significantly improved wound healing in #DiabeticFootUlcer patients, with faster early healing, high rates of epithelialization, and consistent benefits across severity grades. #DiabeticWound
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 6, 2026 at 3:00 AM
Adding leukocyte- and platelet-rich fibrin to standard care significantly improved wound healing in #DiabeticFootUlcer patients, with faster early healing, high rates of epithelialization, and consistent benefits across severity grades. #DiabeticWound
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Study findings indicate that post-PCI quantitative flow ratio (QFR) is a high-value predictor for long-term target vessel failure in in-stent #Restenosis patients, where a QFR of 0.925 correlates with increased clinical risk.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 5, 2026 at 11:45 AM
Study findings indicate that post-PCI quantitative flow ratio (QFR) is a high-value predictor for long-term target vessel failure in in-stent #Restenosis patients, where a QFR of 0.925 correlates with increased clinical risk.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
A multicenter trial shows that standard- and high-definition #colonoscopy have comparable detection efficiency, and HD-WL/HD-NBI offer no advantage over SD-WL, underscoring that improving #endoscopy quality may better optimize screening resources.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 4, 2026 at 1:15 PM
A multicenter trial shows that standard- and high-definition #colonoscopy have comparable detection efficiency, and HD-WL/HD-NBI offer no advantage over SD-WL, underscoring that improving #endoscopy quality may better optimize screening resources.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
On this #WorldCancerDay, let’s honor the "#UnitedbyUnique" theme by advocating the integration of patient-reported outcomes with molecular profiling to drive personalized #PrecisionOncology.
#FightCancer #CancerAwareness
For articles related to cancer: link.springer.com/journal/11596
#FightCancer #CancerAwareness
For articles related to cancer: link.springer.com/journal/11596
February 4, 2026 at 6:15 AM
On this #WorldCancerDay, let’s honor the "#UnitedbyUnique" theme by advocating the integration of patient-reported outcomes with molecular profiling to drive personalized #PrecisionOncology.
#FightCancer #CancerAwareness
For articles related to cancer: link.springer.com/journal/11596
#FightCancer #CancerAwareness
For articles related to cancer: link.springer.com/journal/11596
TOPK was overexpressed in patients with moderately to poorly differentiated CRC receiving #Radiotherapy, while its knockdown significantly enhanced the #Radiosensitivity of CRC cells by reducing the #DNAdamageResponse.
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
February 4, 2026 at 3:20 AM
TOPK was overexpressed in patients with moderately to poorly differentiated CRC receiving #Radiotherapy, while its knockdown significantly enhanced the #Radiosensitivity of CRC cells by reducing the #DNAdamageResponse.
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
Bioinformatic and experimental analyses reveal #SLC9A2 as a #TumorSuppressor in #ColorectalCancer, inhibiting proliferation and metastasis via #MAPK signaling, highlighting its potential as a diagnostic and therapeutic target.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 3, 2026 at 12:20 PM
Bioinformatic and experimental analyses reveal #SLC9A2 as a #TumorSuppressor in #ColorectalCancer, inhibiting proliferation and metastasis via #MAPK signaling, highlighting its potential as a diagnostic and therapeutic target.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
TL1A promotes #IntestinalFibrosis by inducing TGF-β1-mediated intestinal fibroblast activation, proliferation, and collagen deposition via TGF-β1/Smad3 pathway, highlighting a critical #TherapeuticTarget for #InflammatoryBowelDisease
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 2, 2026 at 1:45 PM
TL1A promotes #IntestinalFibrosis by inducing TGF-β1-mediated intestinal fibroblast activation, proliferation, and collagen deposition via TGF-β1/Smad3 pathway, highlighting a critical #TherapeuticTarget for #InflammatoryBowelDisease
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
KLF4 suppresses HSC activation!
Researchers show #KLF4 maintains quiescence in #HepaticStellateCells by inhibiting proliferation and activation, suggesting it as a potential therapeutic target for preventing and reversing #LiverFibrosis.
Read: doi.org/10.1007/s115...
Researchers show #KLF4 maintains quiescence in #HepaticStellateCells by inhibiting proliferation and activation, suggesting it as a potential therapeutic target for preventing and reversing #LiverFibrosis.
Read: doi.org/10.1007/s115...
February 1, 2026 at 2:00 PM
KLF4 suppresses HSC activation!
Researchers show #KLF4 maintains quiescence in #HepaticStellateCells by inhibiting proliferation and activation, suggesting it as a potential therapeutic target for preventing and reversing #LiverFibrosis.
Read: doi.org/10.1007/s115...
Researchers show #KLF4 maintains quiescence in #HepaticStellateCells by inhibiting proliferation and activation, suggesting it as a potential therapeutic target for preventing and reversing #LiverFibrosis.
Read: doi.org/10.1007/s115...
This study demonstrates that PCED1B-AS1 expression is upregulated in #HepatocellularCarcinoma, exerting an #Oncogenic role by promoting HCC cell proliferation and invasion via the miR-34a/CD44 axis. #Medsky
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
January 31, 2026 at 9:55 AM
This study demonstrates that PCED1B-AS1 expression is upregulated in #HepatocellularCarcinoma, exerting an #Oncogenic role by promoting HCC cell proliferation and invasion via the miR-34a/CD44 axis. #Medsky
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
Elevated #SerumFerritin is strongly associated with #MAFLD and advanced #LiverFibrosis, independent of iron intake; combined with #diabetes, it poses major risk, highlighting #ferritin as a #biomarker and therapeutic target.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 30, 2026 at 1:01 PM
Elevated #SerumFerritin is strongly associated with #MAFLD and advanced #LiverFibrosis, independent of iron intake; combined with #diabetes, it poses major risk, highlighting #ferritin as a #biomarker and therapeutic target.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
An overview of the #Epidemiology, #Etiology, pathological classification, diagnosis, imaging features, treatment, and #Prognosis of IPNB, while highlighting the similarities and differences between conventional and novel subclassifications of IPNBs.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 30, 2026 at 1:55 AM
An overview of the #Epidemiology, #Etiology, pathological classification, diagnosis, imaging features, treatment, and #Prognosis of IPNB, while highlighting the similarities and differences between conventional and novel subclassifications of IPNBs.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This review explores proton‑activated #GPCRs, pH‑sensing receptors that modulate #ImmuneResponses, highlighting their roles in #InflammatoryDiseases and future directions for understanding immune regulation under pathological conditions.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 29, 2026 at 11:55 AM
This review explores proton‑activated #GPCRs, pH‑sensing receptors that modulate #ImmuneResponses, highlighting their roles in #InflammatoryDiseases and future directions for understanding immune regulation under pathological conditions.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This review summarizes the #Biogenesis, components, and uptake of adipose tissue-derived #Exosomes, describing their role in #MetabolicDisorders and clinical applications while discussing current limitations and future therapeutic perspectives. #Medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 28, 2026 at 2:15 PM
This review summarizes the #Biogenesis, components, and uptake of adipose tissue-derived #Exosomes, describing their role in #MetabolicDisorders and clinical applications while discussing current limitations and future therapeutic perspectives. #Medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
#CymbopogonCitratus #EssentialOil inhibits #Isoproterenol-induced #cardiomyocyte hypertrophy by suppressing #NLRP3Inflammasome signaling and modulating oxidative phosphorylation complex subunits, highlighting its cardioprotective potential. #CVD
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 28, 2026 at 2:05 AM
#CymbopogonCitratus #EssentialOil inhibits #Isoproterenol-induced #cardiomyocyte hypertrophy by suppressing #NLRP3Inflammasome signaling and modulating oxidative phosphorylation complex subunits, highlighting its cardioprotective potential. #CVD
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
In this study, researchers found that #Hypokalemia occurred in 43.75% of gynecological patients recovering from #Anesthesia due to preoperative mechanical bowel preparation, though it had no significant effect on clinical outcomes. #medsky
To read more: doi.org/10.1007/s115...
To read more: doi.org/10.1007/s115...
January 27, 2026 at 1:15 PM
In this study, researchers found that #Hypokalemia occurred in 43.75% of gynecological patients recovering from #Anesthesia due to preoperative mechanical bowel preparation, though it had no significant effect on clinical outcomes. #medsky
To read more: doi.org/10.1007/s115...
To read more: doi.org/10.1007/s115...
Scientists show that #hemophilia carriers in #China frequently harbor identifiable F8/F9 mutations, exhibit variable #ClottingFactor levels with #BleedingRisk in low-level carriers, and display substantial psychological symptom burden.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 26, 2026 at 10:55 AM
Scientists show that #hemophilia carriers in #China frequently harbor identifiable F8/F9 mutations, exhibit variable #ClottingFactor levels with #BleedingRisk in low-level carriers, and display substantial psychological symptom burden.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This study identified that most GPI variants cluster in #Exons 3, 4, 12, and 18, and report novel pathogenic compound heterozygous variants that disrupt hydrogen bonds in highly conserved regions, potentially affecting GPI’s tertiary structure. #Medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 25, 2026 at 1:35 PM
This study identified that most GPI variants cluster in #Exons 3, 4, 12, and 18, and report novel pathogenic compound heterozygous variants that disrupt hydrogen bonds in highly conserved regions, potentially affecting GPI’s tertiary structure. #Medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...