Dr. Caitlin Pepperell
@csp.bsky.social
Evolutionary genomicist, fan of bacteria, infectious diseases physician
Reposted by Dr. Caitlin Pepperell
Reposted by Dr. Caitlin Pepperell
Two ERC-funded postdoc positions available in the team - one here and second to follow - please repost! jobs.ncl.ac.uk/job/Newcastl...
Research Associate Genetic and functional analysis of Gram positive secretion systems and substrates
Research Associate Genetic and functional analysis of Gram positive secretion systems and substrates
jobs.ncl.ac.uk
April 9, 2025 at 12:29 PM
Two ERC-funded postdoc positions available in the team - one here and second to follow - please repost! jobs.ncl.ac.uk/job/Newcastl...
Reposted by Dr. Caitlin Pepperell
🧪 We've published our first paper on Gardnerella. There is extensive phase variation in all the Gardnerella species we examined. It effects surface proteins, toxin production, and human cervix infection ex vivo. doi.org/10.1128/msph...
June 28, 2024 at 2:06 PM
🧪 We've published our first paper on Gardnerella. There is extensive phase variation in all the Gardnerella species we examined. It effects surface proteins, toxin production, and human cervix infection ex vivo. doi.org/10.1128/msph...
Hot off the press! Our research on transcriptome evolution of mega-pathogen M. tuberculosis: journals.plos.org/plospathogen...
aka what happens to the transcriptome when you select for biofilm growth?
aka what happens to the transcriptome when you select for biofilm growth?
Adaptation of the Mycobacterium tuberculosis transcriptome to biofilm growth
Author summary Understanding mechanisms of resistance and tolerance in Mycobacterium tuberculosis (M. tb) can help us develop new treatments that capitalize on M. tb’s vulnerabilities. Here we used tr...
journals.plos.org
April 19, 2024 at 2:45 PM
Hot off the press! Our research on transcriptome evolution of mega-pathogen M. tuberculosis: journals.plos.org/plospathogen...
aka what happens to the transcriptome when you select for biofilm growth?
aka what happens to the transcriptome when you select for biofilm growth?
Reposted by Dr. Caitlin Pepperell
Whoa. Redux of a paper from 12 years ago with the opposite effect: sweeps and persistence not brief perturbation 🧪🧬
A short course of antibiotics selects for persistent resistance in the human gut https://www.biorxiv.org/content/10.1101/2023.09.04.556257v1
A short course of antibiotics selects for persistent resistance in the human gut https://www.biorxiv.org/content/10.1101/2023.09.04.556257v1
Understanding the relationship between antibiotic use and the evolution of antimicrobial resistance
www.biorxiv.org
September 7, 2023 at 2:23 AM
Whoa. Redux of a paper from 12 years ago with the opposite effect: sweeps and persistence not brief perturbation 🧪🧬