@collectormask.bsky.social
CAR-T Replacing 'mab' drugs for Alzheimer's? Studies are beginning, but they are in the early stages. You can read more at lifespan.io/news/creatin...
Creating CAR-T Cells Using Current Alzheimer’s Antibodies
Biologically engineered T cells using currently available Alzheimer's drugs directly attack the characteristic amyloid plaques of Alzheimer's disease.
lifespan.io
February 14, 2026 at 7:50 AM
CAR-T Replacing 'mab' drugs for Alzheimer's? Studies are beginning, but they are in the early stages. You can read more at lifespan.io/news/creatin...
"Bio/Acc" means 'bio acceleration' , and it's happening even more in 2026. This tweet is a short summary of the big breaks so far barely 6 weeks in x.com/m_goes_dista...
Mgoes (bio/acc 🤖💉) on X: "you're don't believe in bio/acc? we're barely 6 weeks into 2026 and we've already: >started human age reversal trials (Life Biosciences using Yamanaka factors for glaucoma - we proved aging is reversible in living tissue) >debugged cancer in 5 countries simultaneously (Spain:" / X
you're don't believe in bio/acc? we're barely 6 weeks into 2026 and we've already: >started human age reversal trials (Life Biosciences using Yamanaka factors for glaucoma - we proved aging is reversible in living tissue) >debugged cancer in 5 countries simultaneously (Spain:
x.com
February 14, 2026 at 4:52 AM
"Bio/Acc" means 'bio acceleration' , and it's happening even more in 2026. This tweet is a short summary of the big breaks so far barely 6 weeks in x.com/m_goes_dista...
What are Engram Cells? Learn about them with this quite long article www.cell.com/neuron/fullt... which is worth the read because it shows cognitive regeneration of Alzheimer's mice (and humans have these cells too, so it could also work for them)
Cognitive rejuvenation through partial reprogramming of engram cells
Berdugo-Vega et al. combine partial reprogramming and engram technologies to achieve
molecular rejuvenation of learning-associated neuronal ensembles. Engram reprogramming
counteracts molecular, cellu...
www.cell.com
February 13, 2026 at 10:55 AM
What are Engram Cells? Learn about them with this quite long article www.cell.com/neuron/fullt... which is worth the read because it shows cognitive regeneration of Alzheimer's mice (and humans have these cells too, so it could also work for them)
Singapore scientists are figuring out more of how a known protein DTMF, alerts the brain to make fresh new cells to combat brain disease and brain aging. www.sciencealert.com/scientists-h... how can it be safely added to humans?
Scientists Have Discovered a Protein That Reverses Brain Aging in The Lab
Our brains age along with the rest of our bodies, and as they do, they produce fewer new brain cells.
www.sciencealert.com
February 13, 2026 at 10:24 AM
Singapore scientists are figuring out more of how a known protein DTMF, alerts the brain to make fresh new cells to combat brain disease and brain aging. www.sciencealert.com/scientists-h... how can it be safely added to humans?
France continues their good progress toward an artificial heart that you can leave in there forever (fixes the need for donor organs) Currently Carmat's Aeson heart-replacer works well but is not for 'indefinite use'. See it at x.com/argosaki/sta...
GP Q on X: "France has taken a dramatic step toward redefining modern medicine by unveiling an advanced artificial heart designed to function indefinitely without the need for a human donor. This breakthrough offers new hope to millions of patients worldwide suffering from end-stage heart https://t.co/fy703hxRvx" / X
France has taken a dramatic step toward redefining modern medicine by unveiling an advanced artificial heart designed to function indefinitely without the need for a human donor. This breakthrough offers new hope to millions of patients worldwide suffering from end-stage heart https://t.co/fy703hxRvx
x.com
February 13, 2026 at 10:20 AM
France continues their good progress toward an artificial heart that you can leave in there forever (fixes the need for donor organs) Currently Carmat's Aeson heart-replacer works well but is not for 'indefinite use'. See it at x.com/argosaki/sta...
Spreading the gene editing? They're trying www.newscientist.com/article/2514... you can read a snippet of how that could help with this part of an article.
Gene editing that spreads within the body could cure more diseases
The idea of self-amplifying gene editing is to get cells to pass on packages of CRISPR machinery to their neighbours, boosting the effect
www.newscientist.com
February 13, 2026 at 10:17 AM
Spreading the gene editing? They're trying www.newscientist.com/article/2514... you can read a snippet of how that could help with this part of an article.
1. Discover molecular messenger of aging 2. Figure out how to turn it off! It's ReHMGB1, and Korea needs to turn it off x.com/NextScience/... They published on Metabolism – Clinical and Experimental, as this is a good target for new therapies.
Next Science on X: "🚨 Scientists found a protein that carries "old age signals" through the body — and blocking it literally reversed the damage. In a major breakthrough in aging research, scientists at Korea University’s College of Medicine have discovered that cellular aging can spread https://t.co/zLOJ5YnUdz" / X
🚨 Scientists found a protein that carries "old age signals" through the body — and blocking it literally reversed the damage. In a major breakthrough in aging research, scientists at Korea University’s College of Medicine have discovered that cellular aging can spread https://t.co/zLOJ5YnUdz
x.com
February 13, 2026 at 8:06 AM
1. Discover molecular messenger of aging 2. Figure out how to turn it off! It's ReHMGB1, and Korea needs to turn it off x.com/NextScience/... They published on Metabolism – Clinical and Experimental, as this is a good target for new therapies.
Yeah, it's mouse study still but Partial Cellular Reprogramming is regenerating their brains and even restoring age lost memories. www.cell.com/neuron/fullt... very long paper that explains it well: human trials when?
Cognitive rejuvenation through partial reprogramming of engram cells
Berdugo-Vega et al. combine partial reprogramming and engram technologies to achieve
molecular rejuvenation of learning-associated neuronal ensembles. Engram reprogramming
counteracts molecular, cellu...
www.cell.com
February 12, 2026 at 10:26 AM
Yeah, it's mouse study still but Partial Cellular Reprogramming is regenerating their brains and even restoring age lost memories. www.cell.com/neuron/fullt... very long paper that explains it well: human trials when?
What's the first real AI-made drug? It's Rentosertib (a rare lung disease is fought) It took 30 months and 10x less money than the usual way, thanks to AI being used. x.com/majoragv/sta...
x.com
February 12, 2026 at 10:25 AM
What's the first real AI-made drug? It's Rentosertib (a rare lung disease is fought) It took 30 months and 10x less money than the usual way, thanks to AI being used. x.com/majoragv/sta...
Programmable MRNA theraputics? That would help out with so many different diseases, www.nature.com/articles/s41... (specifically good for 'undruggable' problems) This one is a really long and complicated paper.
Programmable mRNA therapeutics for controlled epigenomic modulation of single and multiplexed gene expression in diverse diseases - Nature Communications
mRNA medicines hold enormous promise for drugging targets outside the reach of classic small molecules. Here, the authors develop a modular platform to design programmable mRNA therapeutics that act b...
www.nature.com
February 12, 2026 at 9:17 AM
Programmable MRNA theraputics? That would help out with so many different diseases, www.nature.com/articles/s41... (specifically good for 'undruggable' problems) This one is a really long and complicated paper.
Well, it IS Q1 2026, and they started the human trial! www.globenewswire.com/news-release... It's ER-100, the FDA cleared it, and it's the first (one of the first?) actual human rejuvenation therapy to launch.
Life Biosciences Announces FDA Clearance of IND Application for ER-100 in Optic Neuropathies
IND clearance marks the first ever cellular rejuvenation therapy using partial epigenetic reprogramming to reach human clinical trials...
www.globenewswire.com
February 12, 2026 at 7:08 AM
Well, it IS Q1 2026, and they started the human trial! www.globenewswire.com/news-release... It's ER-100, the FDA cleared it, and it's the first (one of the first?) actual human rejuvenation therapy to launch.
Rejuvenating the blood brain barrier? As it's such a key component for brain health, this is a great avenue to look into. This very long article www.nature.com/articles/s41... (may want a summary) explains what will be studied.
Strategies for blood–brain barrier rejuvenation and repair - Nature Reviews Drug Discovery
The blood–brain barrier (BBB) is a dynamic interface that tightly regulates the transport of substances from the blood into the brain. BBB dysfunction can occur with ageing and is a hallmark of many m...
www.nature.com
February 12, 2026 at 7:04 AM
Rejuvenating the blood brain barrier? As it's such a key component for brain health, this is a great avenue to look into. This very long article www.nature.com/articles/s41... (may want a summary) explains what will be studied.
Another win for Semaglutide? It's now fighting arthritis independent of weight loss. (people hand-waved it before 'of course if you lose weight your joints are better--this isn't that!) www.cell.com/cell-metabol... the summary says 'actual cartilage restoration', very good news.
Semaglutide ameliorates osteoarthritis progression through a weight loss-independent metabolic restoration mechanism
Qin et al. demonstrated the chondroprotective effects of semaglutide in obesity-related
osteoarthritis. Mechanistically, these effects are independent of body weight loss
and involve metabolic reprogr...
www.cell.com
February 11, 2026 at 10:37 AM
Another win for Semaglutide? It's now fighting arthritis independent of weight loss. (people hand-waved it before 'of course if you lose weight your joints are better--this isn't that!) www.cell.com/cell-metabol... the summary says 'actual cartilage restoration', very good news.
Quite a long article on using TCells to fight Alzheimer's www.pnas.org/doi/10.1073/... , might want to have an AI summarize this long/complex article for you as this seems like a good and new angle
Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease | PNAS
Alzheimer’s disease (AD) is the prevailing cause of age-associated dementia worldwide.
Current standard of care relies on antibody-based immunother...
www.pnas.org
February 11, 2026 at 10:34 AM
Quite a long article on using TCells to fight Alzheimer's www.pnas.org/doi/10.1073/... , might want to have an AI summarize this long/complex article for you as this seems like a good and new angle
News you want to hear if you...want to hear! Rinri in England has sheffield.ac.uk/research/fea... with Rincell-1, restoration of the hair cells that die/damage and cause hearing loss.
On the verge of reversing deafness
A revolutionary approach to treating hearing loss is emerging. Sheffield researchers are developing novel cell therapies that could repair the damaged inner ear, potentially reversing deafness for man...
sheffield.ac.uk
February 11, 2026 at 10:32 AM
News you want to hear if you...want to hear! Rinri in England has sheffield.ac.uk/research/fea... with Rincell-1, restoration of the hair cells that die/damage and cause hearing loss.
The latest from Isomorphic Labs is great news for health at www.isomorphiclabs.com/articles/the... as it moves beyond the already amazing AlphaFold3.
The Isomorphic Labs Drug Design Engine unlocks a new frontier beyond AlphaFold - Isomorphic Labs
Today, we are excited to share an update on our progress towards a new frontier of drug design. We have unlocked a new paradigm of predictive accuracy in understanding our biomolecular world, allowing...
www.isomorphiclabs.com
February 11, 2026 at 7:28 AM
The latest from Isomorphic Labs is great news for health at www.isomorphiclabs.com/articles/the... as it moves beyond the already amazing AlphaFold3.
15-PGDH returns to the news x.com/CraigBrockie... as their trial (phase 1 on humans) is close to finishing. Inhibiting the PGDH which is a gero-enzyme that breaks cartilage may allow it to grow back properly and stop breaking down, if this works as they hope it will.
🧬Craig Brockie on X: "Stanford scientists may have just killed the $65B knee and hip replacement industry. They made a breakthrough that could regrow aging cartilage and reverse arthritis. Here's the breakdown: https://t.co/7hWxmc9WQX" / X
Stanford scientists may have just killed the $65B knee and hip replacement industry. They made a breakthrough that could regrow aging cartilage and reverse arthritis. Here's the breakdown: https://t.co/7hWxmc9WQX
x.com
February 11, 2026 at 6:59 AM
15-PGDH returns to the news x.com/CraigBrockie... as their trial (phase 1 on humans) is close to finishing. Inhibiting the PGDH which is a gero-enzyme that breaks cartilage may allow it to grow back properly and stop breaking down, if this works as they hope it will.
Finally a solution to endless yearly flu shots? Johnson & Johnson says it's quite possible with a nasal spray that stops EVERY flu (as you know, it changes each year) www.newscientist.com/article/2514... It's called CR9114 and you spray it up your nose 2x/day during risk of infection. (so far)
Nasal spray could prevent infections from any flu strain
An antibody that has the power to neutralise any influenza strain could be widely administered in the form of a nasal spray if a flu pandemic emerges
www.newscientist.com
February 10, 2026 at 10:00 AM
Finally a solution to endless yearly flu shots? Johnson & Johnson says it's quite possible with a nasal spray that stops EVERY flu (as you know, it changes each year) www.newscientist.com/article/2514... It's called CR9114 and you spray it up your nose 2x/day during risk of infection. (so far)
The pancreatic cancer news from Spain's top guy the other day (he had to get crowd funded--and did!) gets a deeper look by this guy in Spain as to the reasons x.com/enricross196... it's a longer tweet if you want to know more.
x.com
February 10, 2026 at 6:52 AM
The pancreatic cancer news from Spain's top guy the other day (he had to get crowd funded--and did!) gets a deeper look by this guy in Spain as to the reasons x.com/enricross196... it's a longer tweet if you want to know more.
Stopping the "go" signal on cancer doesn't harm healthy cells and stops it in its tracks: and it's being tested on a human already. www.sciencedaily.com/releases/202... (being as this is a 2025 article) A safer approach for multiple types of cancer if/when the trial succeeds.
Breakthrough cancer therapy stops tumor growth without harming healthy cells
Scientists have found a new way to stop cancer growth without damaging healthy cells. Researchers from the Francis Crick Institute and Vividion Therapeutics discovered a compound that blocks the signa...
www.sciencedaily.com
February 9, 2026 at 4:02 AM
Stopping the "go" signal on cancer doesn't harm healthy cells and stops it in its tracks: and it's being tested on a human already. www.sciencedaily.com/releases/202... (being as this is a 2025 article) A safer approach for multiple types of cancer if/when the trial succeeds.
The last 7 days have apparently been quite something for discoveries x.com/m_goes_dista... including anti-cancer progress around the world and accelerating experiments with AI help to discover more things faster and for less money.
Mgoes (bio/acc 🤖💉) on X: "i think we're back biology is finally moving at compute speed last 7 days alone have been insane 1. multiple cancer breakthroughs in one week >turkish scientist Aziz Sancar (Nobel laureate): complete tumor elimination in glioblastoma (deadliest brain cancer) mice using EdU + https://t.co/AxshPVfmSU" / X
i think we're back biology is finally moving at compute speed last 7 days alone have been insane 1. multiple cancer breakthroughs in one week >turkish scientist Aziz Sancar (Nobel laureate): complete tumor elimination in glioblastoma (deadliest brain cancer) mice using EdU + https://t.co/AxshPVfmSU
x.com
February 9, 2026 at 3:41 AM
The last 7 days have apparently been quite something for discoveries x.com/m_goes_dista... including anti-cancer progress around the world and accelerating experiments with AI help to discover more things faster and for less money.
Kidney Conversion? There is now! An enzyme converts a kidney into Type 0 to transplant into anyone, and this is what it looks like news.ubc.ca/2025/10/univ... (And that was back in 2025, so they're even further along now!)
UBC enzyme technology clears first human test toward universal donor organs for transplantation - UBC News
UBC-developed enzymes successfully converted a kidney to universal type O for transplant, marking a major step toward faster, more compatible organ donations.
news.ubc.ca
February 8, 2026 at 8:05 PM
Kidney Conversion? There is now! An enzyme converts a kidney into Type 0 to transplant into anyone, and this is what it looks like news.ubc.ca/2025/10/univ... (And that was back in 2025, so they're even further along now!)
Let's talk anti-aging with a longer article... x.com/VraserX/stat... Lots of speculation, but this stuff should be discussed.
x.com
February 8, 2026 at 8:54 AM
Let's talk anti-aging with a longer article... x.com/VraserX/stat... Lots of speculation, but this stuff should be discussed.
Usually this avoids rumors...but this seems a bit more substantial, x.com/Kekius_Sage/... billionaires and Nobel prize winners looking to longevity could mean amazing news to end disease if it's the real deal.
Kekius Maximus on X: "🚨: Jeff Bezos and a group of investors are reported to have committed around $3 billion to Altos Labs — a longevity startup focused on cellular rejuvenation and cell reprogramming approaches that could help pave the way for future AGE REVERSAL GENE THERAPY. https://t.co/vke9VgnTLw" / X
🚨: Jeff Bezos and a group of investors are reported to have committed around $3 billion to Altos Labs — a longevity startup focused on cellular rejuvenation and cell reprogramming approaches that could help pave the way for future AGE REVERSAL GENE THERAPY. https://t.co/vke9VgnTLw
x.com
February 8, 2026 at 8:50 AM
Usually this avoids rumors...but this seems a bit more substantial, x.com/Kekius_Sage/... billionaires and Nobel prize winners looking to longevity could mean amazing news to end disease if it's the real deal.
The NAD vs Alzheimer's appears updated around January 20th as well on Cell www.cell.com/cell-reports... this one's a bit of a deeper dive article, but it looks like good news.
Pharmacologic reversal of advanced Alzheimer’s disease in mice and identification of potential therapeutic nodes in human brain
Chaubey et al. demonstrate that restoration of brain resilience reverses advanced
disease in two different mouse models of Alzheimer’s disease (AD), challenging the
century-long dogma of AD irreversib...
www.cell.com
February 8, 2026 at 8:48 AM
The NAD vs Alzheimer's appears updated around January 20th as well on Cell www.cell.com/cell-reports... this one's a bit of a deeper dive article, but it looks like good news.