Cristina Nuevo-Tapioles
@cnuevotapioles.bsky.social
Mitochondrial biology and cancer ••• Postdoctoral fellow at
NYU Langone Grossman School of Medicine. Emerald Foundation Inc. Fellow. Leading Edge Fellow 2024 |Philips lab| +she/her+
NYU Langone Grossman School of Medicine. Emerald Foundation Inc. Fellow. Leading Edge Fellow 2024 |Philips lab| +she/her+
Pinned
The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A
Kochen Rossi et al. performed proximity labeling using the two splice variants of KRAS and defined their differential interactomes. Among the KRAS4A-specific interactors is BIRC6, a large member of the inhibitor of apoptosis proteins. BIRC6 co-localizes with KRAS4A on the Golgi and mono- and di-ubiquitinates KRAS4A but not KRAS4B.
www.cell.com
I am really happy to share that our last work from the Philips lab is now out in Cell Reports! The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A. www.cell.com/cell-reports...
Reposted by Cristina Nuevo-Tapioles
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
November 5, 2025 at 5:48 PM
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
I am honored to have received an Early Stage Investigator award and the opportunity to present my work on mitochondrial biology in Costello Syndrome at the 9th International RASopathies Symposium. I am grateful for the chance to discuss science and life’s challenges with everyone at this meeting.
The 9th International #RASopathies Symposium brought together a really fantastic group of participants & attendees. Inspiring to see the new generation coming up.
PRIORITY1️⃣Repositioning therapeutics developed for RAS-ERK signaling in oncology for the mosaic & syndromic RASopathy conditions 🙏
🧪
PRIORITY1️⃣Repositioning therapeutics developed for RAS-ERK signaling in oncology for the mosaic & syndromic RASopathy conditions 🙏
🧪
August 22, 2025 at 7:11 PM
I am honored to have received an Early Stage Investigator award and the opportunity to present my work on mitochondrial biology in Costello Syndrome at the 9th International RASopathies Symposium. I am grateful for the chance to discuss science and life’s challenges with everyone at this meeting.
Welcome to the amazing @leadingedgeprogram.bsky.social !!!
We are thrilled to announce the 2025 Leading Edge Fellows! 40 outstanding postdoctoral fellows doing pioneering research in a wide range of biological and biomedical disciplines.
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
May 28, 2025 at 5:30 PM
Welcome to the amazing @leadingedgeprogram.bsky.social !!!
Applications are still open for the 2025 Leading Edge cohort! Deadline is Feb 3, 2025.
Leading Edge is celebrating a milestone: 100 (actually 102!) new assistant professors!!! 🎉🥳🎊
Learn more about them:
www.leadingedgesymposium.org/fellows/
Applications are now open for the 2025 Leading Edge cohort! (Deadline Feb 3).
You do NOT need to be ready for the job market to apply.
Learn more about them:
www.leadingedgesymposium.org/fellows/
Applications are now open for the 2025 Leading Edge cohort! (Deadline Feb 3).
You do NOT need to be ready for the job market to apply.
January 13, 2025 at 2:58 PM
Applications are still open for the 2025 Leading Edge cohort! Deadline is Feb 3, 2025.
I am really happy to share that our last work from the Philips lab is now out in Cell Reports! The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A. www.cell.com/cell-reports...
The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A
Kochen Rossi et al. performed proximity labeling using the two splice variants of KRAS and defined their differential interactomes. Among the KRAS4A-specific interactors is BIRC6, a large member of the inhibitor of apoptosis proteins. BIRC6 co-localizes with KRAS4A on the Golgi and mono- and di-ubiquitinates KRAS4A but not KRAS4B.
www.cell.com
December 20, 2024 at 5:18 PM
I am really happy to share that our last work from the Philips lab is now out in Cell Reports! The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A. www.cell.com/cell-reports...
Reposted by Cristina Nuevo-Tapioles
I’m excited to share new work out of the lab in Nature Metabolism today on the impact of tumor-relevant glucose concentrations on the response to pyrimidine synthesis inhibitors. t.co/9hOGW4x97T. PDF: rdcu.be/d1vkV
https://www.nature.com/articles/s42255-024-01166-w
t.co
November 26, 2024 at 7:58 PM
I’m excited to share new work out of the lab in Nature Metabolism today on the impact of tumor-relevant glucose concentrations on the response to pyrimidine synthesis inhibitors. t.co/9hOGW4x97T. PDF: rdcu.be/d1vkV
Very cool and inspiring lecture tonight from the Nobel Laureate
@ardemp.bsky.social organized by The Harvey Society. I’m definitely a PIEZO fan now!
@ardemp.bsky.social organized by The Harvey Society. I’m definitely a PIEZO fan now!
November 22, 2024 at 3:12 AM
Very cool and inspiring lecture tonight from the Nobel Laureate
@ardemp.bsky.social organized by The Harvey Society. I’m definitely a PIEZO fan now!
@ardemp.bsky.social organized by The Harvey Society. I’m definitely a PIEZO fan now!
Hola Bluesky! 🌟
My name is Cristina, and I am a postdoctoral fellow in the Philips lab at NYU School of Medicine. During my PhD, I trained as a mitochondrial biologist, and I am currently exploring the fascinating role of this dynamic organelle in cancer and rare disorders.
My name is Cristina, and I am a postdoctoral fellow in the Philips lab at NYU School of Medicine. During my PhD, I trained as a mitochondrial biologist, and I am currently exploring the fascinating role of this dynamic organelle in cancer and rare disorders.
November 17, 2024 at 9:35 PM
Hola Bluesky! 🌟
My name is Cristina, and I am a postdoctoral fellow in the Philips lab at NYU School of Medicine. During my PhD, I trained as a mitochondrial biologist, and I am currently exploring the fascinating role of this dynamic organelle in cancer and rare disorders.
My name is Cristina, and I am a postdoctoral fellow in the Philips lab at NYU School of Medicine. During my PhD, I trained as a mitochondrial biologist, and I am currently exploring the fascinating role of this dynamic organelle in cancer and rare disorders.
Reposted by Cristina Nuevo-Tapioles
If you want to follow awesome women and non-binary early career scientists, the starter pack of Leading Edge Fellows is here!
go.bsky.app/He3EAcq
go.bsky.app/He3EAcq
November 10, 2024 at 9:40 PM
If you want to follow awesome women and non-binary early career scientists, the starter pack of Leading Edge Fellows is here!
go.bsky.app/He3EAcq
go.bsky.app/He3EAcq