Christopher Rose
@cmichaelrose.bsky.social
Director of Discovery Proteomics & Group Leader @Genentech. Passion for developing proteomics technologies that fuel therapeutic discovery. Posts are mine.
As of now the only way to remove 126 is to take reporter ions to ion trap and isolate there. We did that in our Nature Methods paper, but you lose some 127. Other way would be to raise RF amplitude enough to create a low mass cutoff. Interesting idea, but would require some instrumentation changes.
News in Proteomics Research blog post | SCOPE-X - Boost your multiplex single cell relative signal with this one trick! proteomicsnews.blogs...
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#proteomics #prot-other
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#proteomics #prot-other
January 25, 2024 at 9:50 PM
As of now the only way to remove 126 is to take reporter ions to ion trap and isolate there. We did that in our Nature Methods paper, but you lose some 127. Other way would be to raise RF amplitude enough to create a low mass cutoff. Interesting idea, but would require some instrumentation changes.
Check out this Postdoctoral position! Two great labs at Genentech to be co-mentored by. You get to work in our department. You can see me as much (or as little) as you want!
Postdoctoral Fellow - Proteomics of Neurodegeneration, Ori/Bingol Labs - South San Francisco - Genentech | www.theladders.com/j...
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#proteomics #prot-jobs
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#proteomics #prot-jobs
October 31, 2023 at 11:15 PM
Check out this Postdoctoral position! Two great labs at Genentech to be co-mentored by. You get to work in our department. You can see me as much (or as little) as you want!
Excited to share the publication of a large collaborative effort at Genentech to discover shared cancer neoantigen neoepitopes. From 47 cancer neoantigens and 15 HLA alleles we discovered 86 neoepitope-HLA pairs, 65 were novel at acceptance - check it out! www.nature.com/articles/s41...
October 19, 2023 at 3:29 PM
Excited to share the publication of a large collaborative effort at Genentech to discover shared cancer neoantigen neoepitopes. From 47 cancer neoantigens and 15 HLA alleles we discovered 86 neoepitope-HLA pairs, 65 were novel at acceptance - check it out! www.nature.com/articles/s41...
Excited to announce our new preprint to the #proteomics community over here! We combined Hyperplexing and intelligent data acquisition to improve throughput and data completeness of cysteine profiling for #chemoproteomics applications. Also it’s the first description of our API program inSeqAPI 👀
Increasing the Throughput and Reproducibility of Activity-Based Proteome Profiling Studies with Hype...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
September 21, 2023 at 8:14 PM
Excited to announce our new preprint to the #proteomics community over here! We combined Hyperplexing and intelligent data acquisition to improve throughput and data completeness of cysteine profiling for #chemoproteomics applications. Also it’s the first description of our API program inSeqAPI 👀