@cmdooley.bsky.social
1/? 🧬 New Breakthrough in Duchenne Muscular Dystrophy (DMD)!
Our new paper in
@Nature
reveals how utrophin—a dystrophin “backup”—is upregulated in DMD. The key? Transcriptional adaptation (TA), triggered by mutant mRNA decay, not protein loss.
[🔗 Link: www.nature.com/articles/s41...
Our new paper in
@Nature
reveals how utrophin—a dystrophin “backup”—is upregulated in DMD. The key? Transcriptional adaptation (TA), triggered by mutant mRNA decay, not protein loss.
[🔗 Link: www.nature.com/articles/s41...
https://www.nature.com/articles/s41586-024-08539-x]
February 13, 2025 at 10:47 AM
1/? 🧬 New Breakthrough in Duchenne Muscular Dystrophy (DMD)!
Our new paper in
@Nature
reveals how utrophin—a dystrophin “backup”—is upregulated in DMD. The key? Transcriptional adaptation (TA), triggered by mutant mRNA decay, not protein loss.
[🔗 Link: www.nature.com/articles/s41...
Our new paper in
@Nature
reveals how utrophin—a dystrophin “backup”—is upregulated in DMD. The key? Transcriptional adaptation (TA), triggered by mutant mRNA decay, not protein loss.
[🔗 Link: www.nature.com/articles/s41...