Clinical Toxicology
@clinicaltoxicology.bsky.social
Official journal of American Academy of Clinical Toxicology, America's Poison Centers, and the European Association of Poisons Centres and Clinical Toxicologists.
https://www.tandfonline.com/journals/ictx20
https://www.tandfonline.com/journals/ictx20
In this editorial response, the authors caution against routinely stocking ambulances with methylene blue for sodium nitrite poisonings due to considerations regarding cost, infrequent use, and potential harm
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Authors’ reply to comment on “effectiveness and tolerability of methylthioninium chloride (methylene blue) for the treatment of methemoglobinemia: twenty-four years of experience at a single poison center”
Published in Clinical Toxicology (Vol. 63, No. 10, 2025)
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November 4, 2025 at 6:18 PM
In this editorial response, the authors caution against routinely stocking ambulances with methylene blue for sodium nitrite poisonings due to considerations regarding cost, infrequent use, and potential harm
www.tandfonline.com/doi/full/10....
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A 32-year-old male with sodium nitrite poisoning developed profound methemoglobinemia and died despite methylene blue treatment, underscoring the need for prehospital access and early administration.
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Comment on “effectiveness and tolerability of methylthioninium chloride (methylene blue) for the treatment of methemoglobinemia: twenty-four years of experience at a single poison center”
Published in Clinical Toxicology (Vol. 63, No. 10, 2025)
www.tandfonline.com
November 4, 2025 at 6:17 PM
A 32-year-old male with sodium nitrite poisoning developed profound methemoglobinemia and died despite methylene blue treatment, underscoring the need for prehospital access and early administration.
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A 59-year-old woman participated in a Kambo ritual and developed systemic inflammatory response syndrome and acute kidney injury
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November 4, 2025 at 6:17 PM
A 59-year-old woman participated in a Kambo ritual and developed systemic inflammatory response syndrome and acute kidney injury
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In this retrospective chart review from Taiwan, recreational use of etomidate analogues (particularly in “Zombie Vape” products) most commonly caused delirium and drowsiness
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November 4, 2025 at 6:16 PM
In this retrospective chart review from Taiwan, recreational use of etomidate analogues (particularly in “Zombie Vape” products) most commonly caused delirium and drowsiness
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A 77-year-old man presented with odynophagia and drooling after unintentionally ingesting only 1 mL of 10% benzalkonium chloride and 1% isopropyl methyl phenol.
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November 4, 2025 at 6:15 PM
A 77-year-old man presented with odynophagia and drooling after unintentionally ingesting only 1 mL of 10% benzalkonium chloride and 1% isopropyl methyl phenol.
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A 63-year-old female with a history of psoriasis started taking oral methotrexate and developed a desquamating rash. She received treatment with calcium folinate and made a full recovery.
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November 4, 2025 at 6:14 PM
A 63-year-old female with a history of psoriasis started taking oral methotrexate and developed a desquamating rash. She received treatment with calcium folinate and made a full recovery.
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A 4-year-old boy fell developed a periorbital mass two months after falling onto a thermometer containing elemental mercury. He required surgical removal of fibrous tissue, glass, and leaked elemental mercury.
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November 4, 2025 at 6:14 PM
A 4-year-old boy fell developed a periorbital mass two months after falling onto a thermometer containing elemental mercury. He required surgical removal of fibrous tissue, glass, and leaked elemental mercury.
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Four patients ingested wild mushrooms they misidentified as edible, later determined to be Psilocybe keralensis. All patients developed hypertension, and one had myocardial injury.
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Dynamic myocardial injury and variable hallucination latency in Psilocybe keralensis poisoning: a molecularly confirmed case series from China
Psychoactive Psilocybe spp. mushrooms pose significant public health risks. We report a cluster of Psilocybe keralensis poisonings in Chengdu, China, highlighting its unique clinical features and c...
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November 4, 2025 at 6:12 PM
Four patients ingested wild mushrooms they misidentified as edible, later determined to be Psilocybe keralensis. All patients developed hypertension, and one had myocardial injury.
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Two patients with horse dander allergy developed life-threatening anaphylaxis after receiving antivenom.
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Life-threatening anaphylaxis following antivenom administration in two patients with horse dander allergy
Antivenom is used to treat systemic envenomation and is immunoglobulin G raised from animals, mainly horses, inoculated by venom.We report two cases of life-threatening anaphylaxis following the ad...
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November 4, 2025 at 6:11 PM
Two patients with horse dander allergy developed life-threatening anaphylaxis after receiving antivenom.
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In this retrospective analysis of poison center data, midodrine exposures increased by 714% between 2001 and 2023. Most exposures were managed at home.
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November 4, 2025 at 6:08 PM
In this retrospective analysis of poison center data, midodrine exposures increased by 714% between 2001 and 2023. Most exposures were managed at home.
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In this retrospective cohort study of poison center cases in Thailand, cannabis exposures increased among children and adolescents during the recreational cannabis law period.
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November 4, 2025 at 6:05 PM
In this retrospective cohort study of poison center cases in Thailand, cannabis exposures increased among children and adolescents during the recreational cannabis law period.
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In this retrospective case series of 13 patients exposed to glyoxylic acid–containing hair-straightening products, 12 patients had acute kidney injury. Urinalysis showed calcium oxalate crystals in 27% of patients.
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November 4, 2025 at 6:04 PM
In this retrospective case series of 13 patients exposed to glyoxylic acid–containing hair-straightening products, 12 patients had acute kidney injury. Urinalysis showed calcium oxalate crystals in 27% of patients.
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In this retrospective chart review of copperhead snakebite patients, lower-than-recommended doses of Crotalidae polyvalent immune Fab (ovine) were commonly used and were not associated with worse clinical outcomes or frequent antivenom redosing.
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November 4, 2025 at 6:04 PM
In this retrospective chart review of copperhead snakebite patients, lower-than-recommended doses of Crotalidae polyvalent immune Fab (ovine) were commonly used and were not associated with worse clinical outcomes or frequent antivenom redosing.
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In this retrospective chart review of copperhead snakebite patients, lower-than-recommended doses of Crotalidae polyvalent immune Fab (ovine) were commonly used and were not associated with worse clinical outcomes or frequent antivenom redosing.
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November 4, 2025 at 6:04 PM
In this retrospective chart review of copperhead snakebite patients, lower-than-recommended doses of Crotalidae polyvalent immune Fab (ovine) were commonly used and were not associated with worse clinical outcomes or frequent antivenom redosing.
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In this retrospective cohort study of acute paraquat poisoned patients, a composite index using routine blood and urine tests at admission was found to have strong predictive performances (when score was ≥5, probability of predictive mortality was 94%).
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November 4, 2025 at 6:03 PM
In this retrospective cohort study of acute paraquat poisoned patients, a composite index using routine blood and urine tests at admission was found to have strong predictive performances (when score was ≥5, probability of predictive mortality was 94%).
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In this case series, 22 patients with severe methanol poisoning treated with oral ethanol and hemodialysis all survived
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November 4, 2025 at 6:02 PM
In this case series, 22 patients with severe methanol poisoning treated with oral ethanol and hemodialysis all survived
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In this prospective observational study, schistocytes on peripheral blood smear was strongly associated with acute kidney injury and prolonged hospitalization in snakebite patients.
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November 4, 2025 at 6:01 PM
In this prospective observational study, schistocytes on peripheral blood smear was strongly associated with acute kidney injury and prolonged hospitalization in snakebite patients.
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In this cross-sectional laboratory study of urine-drug screens, the number of xylazine-positive and fentanyl-positive urine tests were found to have increased over time, even as concentrations of urine xylazine and fentanyl have declined.
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November 4, 2025 at 6:00 PM
In this cross-sectional laboratory study of urine-drug screens, the number of xylazine-positive and fentanyl-positive urine tests were found to have increased over time, even as concentrations of urine xylazine and fentanyl have declined.
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In a review of 8 randomized controlled trials, IV magnesium sulfate in organophosphate poisoning was linked to lower mortality and reduced atropine use.
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November 4, 2025 at 5:59 PM
In a review of 8 randomized controlled trials, IV magnesium sulfate in organophosphate poisoning was linked to lower mortality and reduced atropine use.
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The North American Congress of Clinical Toxicology 2025 abstracts are here! Which ones are your favorites?
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North American Congress of Clinical Toxicology (NACCT) 2025
Published in Clinical Toxicology (Vol. 63, No. sup3, 2025)
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September 16, 2025 at 9:04 PM
The North American Congress of Clinical Toxicology 2025 abstracts are here! Which ones are your favorites?
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In this retrospective review of cases where patients received flumazenil, seizures occurred in only a small amount (2.6%) of patients
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September 16, 2025 at 9:04 PM
In this retrospective review of cases where patients received flumazenil, seizures occurred in only a small amount (2.6%) of patients
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In this retrospective review of 50,323 unintentional mushroom exposures in children ≤5 years, major outcomes were quite rare
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September 16, 2025 at 9:01 PM
In this retrospective review of 50,323 unintentional mushroom exposures in children ≤5 years, major outcomes were quite rare
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In this retrospective study of 64 cases of adverse effects from consumed liquorice, liquorice-related effects were found to be rare but had high severity.
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September 16, 2025 at 8:58 PM
In this retrospective study of 64 cases of adverse effects from consumed liquorice, liquorice-related effects were found to be rare but had high severity.
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A study of French poison control centers found that their standardized poisoning causality method for poisoning had moderate inter-rater reliability (κ = 0.55) and good sensitivity
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Evaluation of the reproducibility and validity of the use of the causality assessment method for poisonings designed and applied by the French poison control centres
French poison control centres have developed and use a standardised causality assessment method based on a decision tree for poisoning cases involving a wide range of xenobiotics, which includes fi...
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September 16, 2025 at 8:52 PM
A study of French poison control centers found that their standardized poisoning causality method for poisoning had moderate inter-rater reliability (κ = 0.55) and good sensitivity
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In this study of nearly 31,000 pediatric single-substance exposures associated with seizures, cases nearly doubled from 2009 to 2023. The major contributors to this were diphenhydramine and bupropion.
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September 16, 2025 at 8:50 PM
In this study of nearly 31,000 pediatric single-substance exposures associated with seizures, cases nearly doubled from 2009 to 2023. The major contributors to this were diphenhydramine and bupropion.
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