Chin-Soon Phan
@chinsoonphan.bsky.social
Group Leader at LIOS 🇱🇻🇪🇺 | Past: UMS 🇲🇾 → UWA 🇦🇺 → HU 🇯🇵 → NUS 🇸🇬 | 2019 JSPS Fellow | Natural Products | Biosynthesis | Enzymes |
Lab: https://sites.google.com/view/phanlab/
Lab: https://sites.google.com/view/phanlab/
Happy to share our invited book chapter on marine natural products from Malaysia, Springer, 2025, pp 183-225 (doi.org/10.1007/978-...). Submission invited by Prof. Lik Tong Tan (NTU Singapore). Supported in part by EU project No. 101087181.
Marine Natural Products from Malaysia
Marine natural products are a rich source of chemically diverse and biologically active molecules. Over two decades (2001–2024), a total of 228 marine natural products have been reported from soft corals, red algae, sponges and cyanobacteria collected in...
doi.org
October 2, 2025 at 6:15 PM
Happy to share our invited book chapter on marine natural products from Malaysia, Springer, 2025, pp 183-225 (doi.org/10.1007/978-...). Submission invited by Prof. Lik Tong Tan (NTU Singapore). Supported in part by EU project No. 101087181.
Happy to share our recent works on cross-linking enzymes, ShyB and MpoB involved in RiPP biosynthesis | Organic Letters doi.org/10.1021/acs.... | RSC Chemical Biology doi.org/10.1039/D5CB...
P450 Biarylitide Synthase ShyB Catalyzes the Cross-Link Between His-C2 and Tyr-O4 on the Precursor Peptide
Biarylitides are a new class of ribosomally synthesized and post-translationally modified peptides (RiPPs) with the unique feature of biaryl C–C, C–N, or C–O cross-links installed by P450 biarylitide ...
doi.org
July 24, 2025 at 4:08 PM
Happy to share our recent works on cross-linking enzymes, ShyB and MpoB involved in RiPP biosynthesis | Organic Letters doi.org/10.1021/acs.... | RSC Chemical Biology doi.org/10.1039/D5CB...
We are organizing our second workshop in this June at Riga with four Invited Speakers, Yvain Nicolet, Robin Teufel, Joleen Masschelein and Florian Hubrich.
April 24, 2025 at 7:55 AM
We are organizing our second workshop in this June at Riga with four Invited Speakers, Yvain Nicolet, Robin Teufel, Joleen Masschelein and Florian Hubrich.
Happy to share our first independent work. We studied radical SAM enzyme, WprB catalyze Trp-to-Arg crosslink | ACS Chem Biol
doi.org/10.1021/acsc...
doi.org/10.1021/acsc...
Radical SAM Enzyme WprB Catalyzes Uniform Cross-Link Topology between Trp-C5 and Arg-Cγ on the Precursor Peptide
Cross-link containing products from ribosomally synthesized and post-translationally modified peptides (RiPPs) are generated by radical SAM enzymes (rSAM). Here, we bioinformatically expanded rSAM enz...
doi.org
February 2, 2025 at 8:24 PM
Happy to share our first independent work. We studied radical SAM enzyme, WprB catalyze Trp-to-Arg crosslink | ACS Chem Biol
doi.org/10.1021/acsc...
doi.org/10.1021/acsc...