Chathuddasie Amarasinghe
chathuddasie.bsky.social
Chathuddasie Amarasinghe
@chathuddasie.bsky.social
Biophysicist | Microscopist | Grad Student
Reposted by Chathuddasie Amarasinghe
Our latest work is out in PNAS!🎉
We show that nonequilibrium polysome dynamics help drive sister chromosomes apart. The closing division septum also contributes via steric interactions.👇
www.pnas.org/doi/10.1073/...

#MicroSky #Microbiology #Biophysics #CellBiology
November 9, 2025 at 2:05 AM
How do bacteria separate their chromosomes without the mitotic spindle machinery?
Our new PNAS paper reveals that E. coli relies on the dynamics of mRNA–ribosome complexes, together with cell constriction, to drive daughter chromosome separation.

📄 Read more: www.pnas.org/doi/10.1073/...
The role of active mRNA–ribosome dynamics and closing constriction in daughter chromosome separation in Escherichia coli | PNAS
The mechanisms by which two sister chromosomes separate and partition into daughter cells in bacteria remain poorly understood. A recent theoretica...
www.pnas.org
November 6, 2025 at 10:14 PM
We're excited to share our new preprint exploring how active mRNA-ribosome dynamics and closing constriction shape chromosome segregation in E. coli.
www.biorxiv.org/content/10.1...

#biophysics #nucleoid
The role of active mRNA-ribosome dynamics and closing constriction in daughter chromosome separation in Escherichia coli
The mechanisms by which two sister chromosomes separate and partition into daughter cells in bacteria remain poorly understood. A recent theoretical model has proposed that out-of-equilibrium processe...
www.biorxiv.org
April 10, 2025 at 9:40 PM