Christoffer G. Alexandersen
@cgalexandersen.bsky.social
Maths & neuroscience | Postdoc | Complex Systems Lab, UPenn | Aker Scholar
🧠 New preprint 🧠
We review comp. models of brain activity and protein spread in neurodegeneration, and argue that linking them is key to understanding and intervention
With @danisbassett.bsky.social Y. Iturria-Medina
@mxhend.bsky.social K. Brynildsen @gsbrennan.bsky.social
arxiv.org/abs/2509.05151
We review comp. models of brain activity and protein spread in neurodegeneration, and argue that linking them is key to understanding and intervention
With @danisbassett.bsky.social Y. Iturria-Medina
@mxhend.bsky.social K. Brynildsen @gsbrennan.bsky.social
arxiv.org/abs/2509.05151
Network Models of Neurodegeneration: Bridging Neuronal Dynamics and Disease Progression
Neurodegenerative diseases are characterized by the accumulation of misfolded proteins and widespread disruptions in brain function. Computational modeling has advanced our understanding of these proc...
arxiv.org
September 9, 2025 at 11:34 PM
🧠 New preprint 🧠
We review comp. models of brain activity and protein spread in neurodegeneration, and argue that linking them is key to understanding and intervention
With @danisbassett.bsky.social Y. Iturria-Medina
@mxhend.bsky.social K. Brynildsen @gsbrennan.bsky.social
arxiv.org/abs/2509.05151
We review comp. models of brain activity and protein spread in neurodegeneration, and argue that linking them is key to understanding and intervention
With @danisbassett.bsky.social Y. Iturria-Medina
@mxhend.bsky.social K. Brynildsen @gsbrennan.bsky.social
arxiv.org/abs/2509.05151
Reposted by Christoffer G. Alexandersen
⭐New preprint: "A multiscale theory for network advection-reaction-diffusion"
with @alaingoriely.bsky.social and Emilia Cozzolino
arxiv.org/abs/2509.06546
with @alaingoriely.bsky.social and Emilia Cozzolino
arxiv.org/abs/2509.06546
September 9, 2025 at 7:44 AM
⭐New preprint: "A multiscale theory for network advection-reaction-diffusion"
with @alaingoriely.bsky.social and Emilia Cozzolino
arxiv.org/abs/2509.06546
with @alaingoriely.bsky.social and Emilia Cozzolino
arxiv.org/abs/2509.06546
Reposted by Christoffer G. Alexandersen
Modelling cerebrovascular pathology and the spread of amyloid beta in Alzheimer’s disease: royalsocietypublishing.org/doi/10.1098/... #ProcA #Alzheimers #biophysics
royalsocietypublishing.org
April 4, 2025 at 6:05 PM
Modelling cerebrovascular pathology and the spread of amyloid beta in Alzheimer’s disease: royalsocietypublishing.org/doi/10.1098/... #ProcA #Alzheimers #biophysics
Reposted by Christoffer G. Alexandersen
In this paper, we connect local damage to brain vasculature to global progression of toxic proteins leading to neurodegenerative diseases.
royalsocietypublishing.org/doi/epdf/10....
We identify situations where disease initiation can be caused by focal hypoperfusion following vascular injury.
royalsocietypublishing.org/doi/epdf/10....
We identify situations where disease initiation can be caused by focal hypoperfusion following vascular injury.
April 2, 2025 at 5:30 PM
In this paper, we connect local damage to brain vasculature to global progression of toxic proteins leading to neurodegenerative diseases.
royalsocietypublishing.org/doi/epdf/10....
We identify situations where disease initiation can be caused by focal hypoperfusion following vascular injury.
royalsocietypublishing.org/doi/epdf/10....
We identify situations where disease initiation can be caused by focal hypoperfusion following vascular injury.