CalcinottoLab
@calcinottolab.bsky.social
We pioneer next-generation immunotherapy by blocking pro-tumoral immune activity. Our research uncovers how tumor cells, microbiota, and immune infiltrates drive hormone-dependent and BRCA-mutated cancers.
https://ior.usi.ch/group/cancer-immunotherapy
https://ior.usi.ch/group/cancer-immunotherapy
Pinned
CalcinottoLab
@calcinottolab.bsky.social
· Jul 31
Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition - Nature Communications
Tumor-associated neutrophils exhibit heterogeneity in breast cancer. Here, the authors identify a distinct precursor population (PreNeu) in estrogen receptor-positive tumors. PreNeu suppress homologou...
www.nature.com
🚀 Excited to share our latest publication!
👉 www.nature.com/articles/s41...
A fantastic collaboration with an incredible team.
#BreastCancer #Neutrophils #TumorMicroenvironment #PARPinhibitors #DNARepair #NatureCommunications #CancerImmunology #CalcinottoLab
👉 www.nature.com/articles/s41...
A fantastic collaboration with an incredible team.
#BreastCancer #Neutrophils #TumorMicroenvironment #PARPinhibitors #DNARepair #NatureCommunications #CancerImmunology #CalcinottoLab
Reposted by CalcinottoLab
#IORnews
The Cancer Immunotherapy lab, led by Prof. A. Calcinotto, uncover a new immune–tumor interaction in ER+ breast cancer, opening the way for targeted therapies.
🔗Read more: ior.usi.ch/events-news/...
@calcinottolab.bsky.social
The Cancer Immunotherapy lab, led by Prof. A. Calcinotto, uncover a new immune–tumor interaction in ER+ breast cancer, opening the way for targeted therapies.
🔗Read more: ior.usi.ch/events-news/...
@calcinottolab.bsky.social
August 19, 2025 at 12:21 PM
#IORnews
The Cancer Immunotherapy lab, led by Prof. A. Calcinotto, uncover a new immune–tumor interaction in ER+ breast cancer, opening the way for targeted therapies.
🔗Read more: ior.usi.ch/events-news/...
@calcinottolab.bsky.social
The Cancer Immunotherapy lab, led by Prof. A. Calcinotto, uncover a new immune–tumor interaction in ER+ breast cancer, opening the way for targeted therapies.
🔗Read more: ior.usi.ch/events-news/...
@calcinottolab.bsky.social
🚀 Excited to share our latest publication!
👉 www.nature.com/articles/s41...
A fantastic collaboration with an incredible team.
#BreastCancer #Neutrophils #TumorMicroenvironment #PARPinhibitors #DNARepair #NatureCommunications #CancerImmunology #CalcinottoLab
👉 www.nature.com/articles/s41...
A fantastic collaboration with an incredible team.
#BreastCancer #Neutrophils #TumorMicroenvironment #PARPinhibitors #DNARepair #NatureCommunications #CancerImmunology #CalcinottoLab
Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition - Nature Communications
Tumor-associated neutrophils exhibit heterogeneity in breast cancer. Here, the authors identify a distinct precursor population (PreNeu) in estrogen receptor-positive tumors. PreNeu suppress homologou...
www.nature.com
July 31, 2025 at 1:53 PM
🚀 Excited to share our latest publication!
👉 www.nature.com/articles/s41...
A fantastic collaboration with an incredible team.
#BreastCancer #Neutrophils #TumorMicroenvironment #PARPinhibitors #DNARepair #NatureCommunications #CancerImmunology #CalcinottoLab
👉 www.nature.com/articles/s41...
A fantastic collaboration with an incredible team.
#BreastCancer #Neutrophils #TumorMicroenvironment #PARPinhibitors #DNARepair #NatureCommunications #CancerImmunology #CalcinottoLab
Join us for the session “DNA Repair and Immunosurveillance” at #EACR2025, where I’ll be giving a talk on neutrophils and synthetic lethality in breast cancer”
June 17, 2025 at 2:59 PM
Join us for the session “DNA Repair and Immunosurveillance” at #EACR2025, where I’ll be giving a talk on neutrophils and synthetic lethality in breast cancer”
Senescent neutrophils: a hidden role in cancer progression: Trends in Cell Biology www.cell.com/trends/cell-...
Senescent neutrophils: a hidden role in cancer progression
Neutrophils have recently received increased attention in cancer because they contribute
to all stages of cancer. Neutrophils are so far considered to have a short half-life.
However, a growing body o...
www.cell.com
May 8, 2025 at 3:13 PM
Senescent neutrophils: a hidden role in cancer progression: Trends in Cell Biology www.cell.com/trends/cell-...
Getting ready to start!
Join us for this session #AACR2025 where I will be speaking alongside Nicky McGranahan and Ronny Drapkin.
Looking forward to an exciting discussion on how immunology shapes cancer initiation!
1:00 p.m. - 2:30 p.m. — see you there!
Join us for this session #AACR2025 where I will be speaking alongside Nicky McGranahan and Ronny Drapkin.
Looking forward to an exciting discussion on how immunology shapes cancer initiation!
1:00 p.m. - 2:30 p.m. — see you there!
April 27, 2025 at 4:56 PM
Getting ready to start!
Join us for this session #AACR2025 where I will be speaking alongside Nicky McGranahan and Ronny Drapkin.
Looking forward to an exciting discussion on how immunology shapes cancer initiation!
1:00 p.m. - 2:30 p.m. — see you there!
Join us for this session #AACR2025 where I will be speaking alongside Nicky McGranahan and Ronny Drapkin.
Looking forward to an exciting discussion on how immunology shapes cancer initiation!
1:00 p.m. - 2:30 p.m. — see you there!
Thrilled to share that our group will be presenting at a major symposium at the AACR Annual Meeting in Chicago this Sunday!
Catch us at AACR—Chicago, we’re ready!
#AACR25 #CancerResearch #Immunology #SomaticEvolution #EarlyDetection #CancerBiology #TeamScience #SeeYouInChicago
Catch us at AACR—Chicago, we’re ready!
#AACR25 #CancerResearch #Immunology #SomaticEvolution #EarlyDetection #CancerBiology #TeamScience #SeeYouInChicago
April 21, 2025 at 9:25 AM
Thrilled to share that our group will be presenting at a major symposium at the AACR Annual Meeting in Chicago this Sunday!
Catch us at AACR—Chicago, we’re ready!
#AACR25 #CancerResearch #Immunology #SomaticEvolution #EarlyDetection #CancerBiology #TeamScience #SeeYouInChicago
Catch us at AACR—Chicago, we’re ready!
#AACR25 #CancerResearch #Immunology #SomaticEvolution #EarlyDetection #CancerBiology #TeamScience #SeeYouInChicago
Bellinzona is ready to host the next SYIS seminar on April 17!
I’m excited to join the event as a speaker, alongside Christian Pasquali from OM Pharma.
Join us at 5:00 pm (CET) — either in person in Bellinzona or online via Zoom!
I’m excited to join the event as a speaker, alongside Christian Pasquali from OM Pharma.
Join us at 5:00 pm (CET) — either in person in Bellinzona or online via Zoom!
April 16, 2025 at 8:38 PM
Bellinzona is ready to host the next SYIS seminar on April 17!
I’m excited to join the event as a speaker, alongside Christian Pasquali from OM Pharma.
Join us at 5:00 pm (CET) — either in person in Bellinzona or online via Zoom!
I’m excited to join the event as a speaker, alongside Christian Pasquali from OM Pharma.
Join us at 5:00 pm (CET) — either in person in Bellinzona or online via Zoom!
Thrilled to share our new review published by @cp-trendscellbio.bsky.social
In this article, my lab explores the heterogeneity of cancer neutrophils and discusses their implications in both cancer progression and therapy resistance. Check out the full review here:
pubmed.ncbi.nlm.nih.gov/39362804/
In this article, my lab explores the heterogeneity of cancer neutrophils and discusses their implications in both cancer progression and therapy resistance. Check out the full review here:
pubmed.ncbi.nlm.nih.gov/39362804/
Senescent neutrophils: a hidden role in cancer progression - PubMed
Neutrophils have recently received increased attention in cancer because they contribute to all stages of cancer. Neutrophils are so far considered to have a short half-life. However, a growing body o...
pubmed.ncbi.nlm.nih.gov
April 15, 2025 at 4:12 PM
Thrilled to share our new review published by @cp-trendscellbio.bsky.social
In this article, my lab explores the heterogeneity of cancer neutrophils and discusses their implications in both cancer progression and therapy resistance. Check out the full review here:
pubmed.ncbi.nlm.nih.gov/39362804/
In this article, my lab explores the heterogeneity of cancer neutrophils and discusses their implications in both cancer progression and therapy resistance. Check out the full review here:
pubmed.ncbi.nlm.nih.gov/39362804/