Citizens for Alternatives to Animal Research and Experimentation
@caare.bsky.social
CAARE is a national non-profit 501(c)3 organization dedicated to sparing animal suffering by promoting research and testing without animals.
Weill Cornell Medicine and University of Adelaide unveil GoT-Multi, a human-based tool that tracks cancer evolution at single-cell detail, reducing use of animal tests. www.technologynetworks.com/proteomics/n...
New Tool Maps Cancer Evolution at Single-Cell Resolution
Researchers at Weill Cornell Medicine and the University of Adelaide have developed GoT-Multi, a tool that tracks multiple gene mutations and gene activity in individual cancer cells. Unlike earlier m...
www.technologynetworks.com
November 21, 2025 at 12:15 PM
Weill Cornell Medicine and University of Adelaide unveil GoT-Multi, a human-based tool that tracks cancer evolution at single-cell detail, reducing use of animal tests. www.technologynetworks.com/proteomics/n...
University of Glasgow developed a bioengineered human bone marrow model that improves leukemia therapy testing and reduces reliance on animal research. medicalxpress.com/news/2025-11...
Bioengineered bone marrow model successfully used in leukemia research
Scientists at the University of Glasgow have successfully used the first bioengineered bone marrow model to carry out vital cancer research, offering new insights into potential therapies for the dise...
medicalxpress.com
November 20, 2025 at 12:27 PM
University of Glasgow developed a bioengineered human bone marrow model that improves leukemia therapy testing and reduces reliance on animal research. medicalxpress.com/news/2025-11...
UC Davis Health study links anxiety to lower choline levels in the brain, advancing human-based understanding of mental health without poorly translatable animal tests. www.technologynetworks.com/neuroscience...
Anxiety Disorders Linked to Low Choline Levels in the Brain
People with anxiety disorders have lower levels of choline in their brains, according to new research.
www.technologynetworks.com
November 19, 2025 at 12:29 PM
UC Davis Health study links anxiety to lower choline levels in the brain, advancing human-based understanding of mental health without poorly translatable animal tests. www.technologynetworks.com/neuroscience...
Instead of cruel animal experiments, University of Sydney used advanced fMRI in humans to map pain response, revealing endocannabinoid pathways for targeted treatments.
www.sciencedaily.com/releases/202...
www.sciencedaily.com/releases/202...
Breakthrough brain discovery reveals a natural way to relieve pain
Using powerful 7-Tesla brain imaging, researchers mapped how the brainstem manages pain differently across the body. They discovered that distinct regions activate for facial versus limb pain, showing...
www.sciencedaily.com
November 18, 2025 at 12:49 PM
Instead of cruel animal experiments, University of Sydney used advanced fMRI in humans to map pain response, revealing endocannabinoid pathways for targeted treatments.
www.sciencedaily.com/releases/202...
www.sciencedaily.com/releases/202...
Certara’s AI platform aligns with FDA’s new policy to phase out animal tests by using sophisticated computer modeling to more accurately predict drug responses.
technical.ly/sponsored-ar...
technical.ly/sponsored-ar...
How Certara turned the FDA’s animal‑testing shift into innovation
As drug development enters a new era, Certara is expanding its global team of scientists and technologists to lead the shift toward AI-powered testing methods.
technical.ly
November 17, 2025 at 12:22 PM
Certara’s AI platform aligns with FDA’s new policy to phase out animal tests by using sophisticated computer modeling to more accurately predict drug responses.
technical.ly/sponsored-ar...
technical.ly/sponsored-ar...
Duke‑NUS created BrainSTEM , a detailed human brain cell atlas guiding better, animal-free Parkinson’s therapies by improving accuracy and safety of lab-grown human models.
www.sciencedaily.com/releases/202...
www.sciencedaily.com/releases/202...
A groundbreaking brain map could revolutionize Parkinson’s treatment
Duke-NUS scientists unveiled BrainSTEM, a revolutionary single-cell map that captures the full cellular diversity of the developing human brain. The project’s focus on dopamine neurons provides crucia...
www.sciencedaily.com
November 14, 2025 at 12:34 PM
Duke‑NUS created BrainSTEM , a detailed human brain cell atlas guiding better, animal-free Parkinson’s therapies by improving accuracy and safety of lab-grown human models.
www.sciencedaily.com/releases/202...
www.sciencedaily.com/releases/202...
Penn’s tumor‑on‑a‑chip uses modern, animal-free research to show how CAR T cells attack solid tumors, advancing understanding of immunotherapy.
penntoday.upenn.edu/news/tumor-c...
penntoday.upenn.edu/news/tumor-c...
Tumor-on-a-chip offers insight into cancer-fighting cells in immunotherapy | Penn Today
Penn engineers and collaborators have built a living tumor on a chip to expose how cancers block immune attacks, and how one existing drug could make immunotherapy like CAR T more effective against so...
penntoday.upenn.edu
November 13, 2025 at 12:29 PM
Penn’s tumor‑on‑a‑chip uses modern, animal-free research to show how CAR T cells attack solid tumors, advancing understanding of immunotherapy.
penntoday.upenn.edu/news/tumor-c...
penntoday.upenn.edu/news/tumor-c...
On Tuesday the UK unveiled a sweeping and detailed plan to phase out animal testing for drugs in multiple key areas by shifting to superior and humane nonanimal methods.
www.drugtargetreview.com/news/190470/
www.drugtargetreview.com/news/190470/
November 12, 2025 at 12:10 PM
On Tuesday the UK unveiled a sweeping and detailed plan to phase out animal testing for drugs in multiple key areas by shifting to superior and humane nonanimal methods.
www.drugtargetreview.com/news/190470/
www.drugtargetreview.com/news/190470/
Cincinnati Children’s Hospital and Roche develop patient-derived mini livers that reveal drug toxicity missed in animal testing, improving human-relevant safety research. www.sciencedaily.com/releases/202...
Scientists grow mini human livers that predict toxic drug reactions
A new human liver organoid microarray developed by Cincinnati Children’s and Roche recreates immune-driven liver injury in the lab. Built from patient-derived stem cells and immune cells, it accuratel...
www.sciencedaily.com
November 11, 2025 at 12:22 PM
Cincinnati Children’s Hospital and Roche develop patient-derived mini livers that reveal drug toxicity missed in animal testing, improving human-relevant safety research. www.sciencedaily.com/releases/202...
University of Sheffield uses patient-derived models instead of animal tests to reveal patient-specific treatment responses and advance neurodegenerative drug discovery. www.technologynetworks.com/drug-discove...
How Patient-Derived Models Are Empowering Neurodegenerative Disease Drug Discovery
Discover how patient-derived stem cell models are transforming neurodegenerative disease research and drug discovery.
www.technologynetworks.com
November 10, 2025 at 12:48 PM
University of Sheffield uses patient-derived models instead of animal tests to reveal patient-specific treatment responses and advance neurodegenerative drug discovery. www.technologynetworks.com/drug-discove...
German researchers created patient-derived brain organoids to model lissencephaly, a rare brain disorder, revealing new insights without cruel animal testing.
www.technologynetworks.com/neuroscience...
www.technologynetworks.com/neuroscience...
Brain Organoids Bring Insights to Lissencephaly Development and Treatment
New research has developed a brain organoid model to study lissencephaly, a rare genetic disorder.
www.technologynetworks.com
November 7, 2025 at 12:07 PM
German researchers created patient-derived brain organoids to model lissencephaly, a rare brain disorder, revealing new insights without cruel animal testing.
www.technologynetworks.com/neuroscience...
www.technologynetworks.com/neuroscience...
Wyss Institute developed a human-based uterus-on-a-chip to study heavy menstrual bleeding, improving understanding of the disorder without inapplicable animal studies. www.thecrimson.com/article/2025...
Harvard Scientists Build Model Uterus on a Chip to Model Menstruation | News | The Harvard Crimson
Researchers at Harvard’s Wyss Institute are building model uteruses the size of a thumbdrive to diagnose heavy menstrual bleeding, after receiving a grant from the non-profit Wellcome Leap last month.
www.thecrimson.com
November 6, 2025 at 12:45 PM
Wyss Institute developed a human-based uterus-on-a-chip to study heavy menstrual bleeding, improving understanding of the disorder without inapplicable animal studies. www.thecrimson.com/article/2025...
Baylor researchers used human nasal organoids instead of cruel and outdated animal experiments to study how beneficial bacteria in the nose protect against infection.
www.technologynetworks.com/immunology/n...
www.technologynetworks.com/immunology/n...
Nasal Organoids Reveal How Good Bacteria May Prevent Infections
Discover how human nasal organoids reveal bacterial interactions in noses, influencing immune responses and health.
www.technologynetworks.com
November 5, 2025 at 12:16 PM
Baylor researchers used human nasal organoids instead of cruel and outdated animal experiments to study how beneficial bacteria in the nose protect against infection.
www.technologynetworks.com/immunology/n...
www.technologynetworks.com/immunology/n...
University of Fukui conducted an animal-free study to find DNA methylation “scars” from childhood trauma. These human-based biomarkers open new paths for early screening and treatment. www.technologynetworks.com/genomics/new...
How Childhood Trauma Leaves Lasting Epigenetic Marks
A recent study by researchers from the University of Fukui and Hiroshima University in Japan shows that child maltreatment leaves measurable biological “scars” on children’s DNA.
www.technologynetworks.com
November 4, 2025 at 12:19 PM
University of Fukui conducted an animal-free study to find DNA methylation “scars” from childhood trauma. These human-based biomarkers open new paths for early screening and treatment. www.technologynetworks.com/genomics/new...
One of the largest U.S. breeders of research dogs is shutting down after documented abuse—disrupting the supply chain and signaling rising demand for ending animal experiments. www.science.org/content/arti...
Facing claims of animal abuse, a major breeder of research dogs will close its pipeline
Ridglan Farms has agreed to stop selling beagles for scientific studies, leaving just one major U.S. supplier
www.science.org
November 3, 2025 at 12:28 PM
One of the largest U.S. breeders of research dogs is shutting down after documented abuse—disrupting the supply chain and signaling rising demand for ending animal experiments. www.science.org/content/arti...
South Korean researchers developed a retina-on-a-chip to study retinal vein occlusion. The chip accurately mimics human retinal structure and disease progression to advance the search for new treatments without animal tests.
POSTECH team creates retina-on-a-chip that replicates retinal vein occlusion
POSTECH team creates retina-on-a-chip that replicates retinal vein occlusion POSTECH-led team builds 3D bioprinted retina chip that models human retinal vein occlusion
biz.chosun.com
October 31, 2025 at 12:30 PM
South Korean researchers developed a retina-on-a-chip to study retinal vein occlusion. The chip accurately mimics human retinal structure and disease progression to advance the search for new treatments without animal tests.
UVA Health’s human-based biomarker research advances early detection of interstitial lung disease —another example of how cruel animal testing fails to accurately model human biology.
Biomarkers Associated With Interstitial Lung Disease Identified
UVA researchers unveil a breakthrough in detecting interstitial lung disease, focusing on blood biomarkers for ILD to identify risks early.
www.technologynetworks.com
October 30, 2025 at 12:31 PM
UVA Health’s human-based biomarker research advances early detection of interstitial lung disease —another example of how cruel animal testing fails to accurately model human biology.
MIT’s new miBrains use patient-derived human tissue to model brain disease and test drugs, offering a more ethical and scientifically robust alternative to animal experiments:
Scientists grow 3D human brains for personalized medicine study
Built from patient stem cells, MIT’s miBrains let scientists grow individualized human brain models to study disease and test new therapies.
interestingengineering.com
October 29, 2025 at 12:31 PM
MIT’s new miBrains use patient-derived human tissue to model brain disease and test drugs, offering a more ethical and scientifically robust alternative to animal experiments:
McGill University and the Douglas Institute used human-based research to identify brain-cell changes linked to depression, guiding future treatments.
For the first time, scientists pinpoint brain cells linked to depression
Scientists identified two types of brain cells, neurons and microglia, that are altered in people with depression. Through genomic mapping of post-mortem brain tissue, they found major differences in…
www.sciencedaily.com
October 28, 2025 at 1:03 PM
McGill University and the Douglas Institute used human-based research to identify brain-cell changes linked to depression, guiding future treatments.
Karolinska Institutet and Queen Mary researchers use human-based models to reveal how fat tissue structure fuels ovarian cancer spread.
The Hidden Role of Fat Tissue in Ovarian Cancer Metastasis
The physical structure of fat tissues helps ovarian cancer cells invade the body, not just chemical signals.
www.technologynetworks.com
October 27, 2025 at 1:04 PM
Karolinska Institutet and Queen Mary researchers use human-based models to reveal how fat tissue structure fuels ovarian cancer spread.
UC Irvine built a 3D artificial colon from human cells to improve drug testing accuracy and replace cruel and outdated animal studies.
news.uci.edu/2025/10/15/u...
news.uci.edu/2025/10/15/u...
UC Irvine researchers invent a bioelectronic-integrated artificial colon for disease studies, drug screening
Closely matching its human counterpart, replica eliminates need for animal testing
news.uci.edu
October 24, 2025 at 12:29 PM
UC Irvine built a 3D artificial colon from human cells to improve drug testing accuracy and replace cruel and outdated animal studies.
news.uci.edu/2025/10/15/u...
news.uci.edu/2025/10/15/u...
The University of Rochester created a brain-on-a-chip from human tissue to study how sepsis harms the brain—advancing neurodegenerative research without animal testing. medicalxpress.com/news/2025-10...
Brain-on-a-chip technology reveals how sepsis and neurodegenerative diseases damage the brain
In lieu of animal experiments, researchers from the University of Rochester are using state-of-the-art microchips with human tissue to better understand how the brain operates under healthy conditions...
medicalxpress.com
October 23, 2025 at 12:17 PM
The University of Rochester created a brain-on-a-chip from human tissue to study how sepsis harms the brain—advancing neurodegenerative research without animal testing. medicalxpress.com/news/2025-10...
Tell NIH and UMB to end to cruel, unnecessary, and outdated experiments that cut babies out of pregnant baboons.
www.caareusa.org/end_abominab...
www.caareusa.org/end_abominab...
October 22, 2025 at 12:32 PM
Tell NIH and UMB to end to cruel, unnecessary, and outdated experiments that cut babies out of pregnant baboons.
www.caareusa.org/end_abominab...
www.caareusa.org/end_abominab...
Without animal testing, Mass General Brigham found memantine improved social behavior in autistic youth in a clinical trial that used human biomarkers and neuroimaging.
www.technologynetworks.com/drug-discove...
www.technologynetworks.com/drug-discove...
Alzheimer’s Drug May Improve Social Function in Individuals With Autism
A clinical trial of 42 intellectually capable individuals with autism spectrum disorder found that participants tolerated the drug memantine well and showed significant improvements in social function...
www.technologynetworks.com
October 21, 2025 at 12:15 PM
Without animal testing, Mass General Brigham found memantine improved social behavior in autistic youth in a clinical trial that used human biomarkers and neuroimaging.
www.technologynetworks.com/drug-discove...
www.technologynetworks.com/drug-discove...
University of East Anglia created a blood test that diagnoses chronic fatigue syndrome with 96% accuracy using human-based genomic data, and no animal testing.
www.technologynetworks.com/diagnostics/...
www.technologynetworks.com/diagnostics/...
Blood Test Diagnoses Chronic Fatigue Syndrome With 96% Accuracy
Scientists at the University of East Anglia and Oxford Biodynamics have developed a highly accurate blood test to diagnose Chronic Fatigue Syndrome, also known as Myalgic Encephalomyelitis (ME/CFS).
www.technologynetworks.com
October 20, 2025 at 12:10 PM
University of East Anglia created a blood test that diagnoses chronic fatigue syndrome with 96% accuracy using human-based genomic data, and no animal testing.
www.technologynetworks.com/diagnostics/...
www.technologynetworks.com/diagnostics/...