Citizens for Alternatives to Animal Research and Experimentation
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caare.bsky.social
Citizens for Alternatives to Animal Research and Experimentation
@caare.bsky.social
64 followers 15 following 240 posts
CAARE is a national non-profit 501(c)3 organization dedicated to sparing animal suffering by promoting research and testing without animals.
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caare.bsky.social
CAARE exposed 25 years of suffering at UMB. Baby baboons endure dangerous, pointless procedures. Boo’s trauma shows the cruelty. Raise your voice—tell UMB to end these experiments. www.caareusa.org/baboon_babie...
January 15, 2026 at 12:34 PM
caare.bsky.social
MIT has created a computational brain model that mimics neural activity and offers a humane method for studying human cognition without flawed animal tests.
www.technologynetworks.com/informatics/...
Computational Model of the Brain Matches Animals in Learning
A new ‘biomimetic’ model of brain circuits and function at multiple scales produced naturalistic dynamics and learning, and even identified curious behavior by some neurons that had gone unnoticed in ...
www.technologynetworks.com
January 14, 2026 at 12:33 PM
caare.bsky.social
ETH Zurich & Nagoya U. developed a technique to watch flu viruses enter human cells in real time, without using animals and improving antiviral drug testing accuracy.
www.eara.eu/post/new-met...
New method captures flu virus surfing human cells in real-time
Scientists in Switzerland and Japan have captured, in real time and high resolution, the exact moment a flu virus enters a living human cell.
www.eara.eu
January 13, 2026 at 12:15 PM
caare.bsky.social
Johns Hopkins used brain organoids from patients’ cells to identify biomarkers for schizophrenia and bipolar disorder, enabling accurate diagnosis and personalized treatment.
www.sciencedaily.com/releases/202...
Mini brains reveal clear brain signals of schizophrenia and bipolar disorder
Tiny lab-grown brains are offering an unprecedented look at how schizophrenia and bipolar disorder disrupt neural activity. Researchers found distinct electrical firing patterns that could identify th...
www.sciencedaily.com
January 12, 2026 at 12:15 PM
caare.bsky.social
Indiana University researchers found sex-based differences in multiple myeloma by analyzing human cells, improving potential treatments without animal tests.
www.technologynetworks.com/cancer-resea...
Multiple Myeloma Develops Differently in Men and Women
Researchers have uncovered differences in how multiple myeloma develops and progresses in men and in women, which could lead to earlier detection and sex-specific treatments.
www.technologynetworks.com
January 9, 2026 at 1:17 PM
caare.bsky.social
Human lung-on-a-chip built from a single donor’s stem cells mimics breathing and infection, enabling personalized lung research, unobtainable through animal testing. medicalxpress.com/news/2025-12...
First breathing 'lung-on-chip' developed using genetically identical cells
Researchers at the Francis Crick Institute and AlveoliX have developed the first human lung-on-chip model using stem cells taken from only one person. These chips simulate breathing motions and lung d...
medicalxpress.com
January 8, 2026 at 11:49 AM
caare.bsky.social
Korean scientists at KAIST have advanced human intestinal stem cell regeneration using an animal-free culture, improving safety and scientific reliability.
www.news-medical.net/news/2025123...
Advancing stem cell regeneration through animal-free culture systems
Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection...
www.news-medical.net
January 7, 2026 at 12:14 PM
caare.bsky.social
University of Navarra mapped how cancer genes interact using human data, advancing ethical, human-based cancer research without outdated animal testing.
www.technologynetworks.com/proteomics/n...
Scientists Built a Map of How Cancer Genes Talk to Each Other
Researchers developed RNACOREX, an open-source tool that maps gene regulation networks by analyzing miRNA–mRNA interactions. Validated across 13 cancer types using TCGA data, the software predicts pat...
www.technologynetworks.com
January 6, 2026 at 12:36 PM
caare.bsky.social
Studying human placental tissue and not animals, scientists at Flinders University found that placental aging, indicated by circular RNAs, may be a cause of stillbirths.
www.technologynetworks.com/proteomics/n...
The Placenta Can Age Too Quickly During Pregnancy
Researchers found that placentas in stillbirth cases show signs of accelerated biological aging driven by circular RNAs. These molecules damage DNA, impair placental function and can be detected in ma...
www.technologynetworks.com
January 5, 2026 at 12:13 PM
caare.bsky.social
UBC researchers studied human cell lines to show CBD and THC slow ovarian cancer cell growth and migration, highlighting animal-free approaches to studying cancer.
www.sciencedaily.com/releases/202...
Cannabis compounds show unexpected power against ovarian cancer
Scientists have discovered that key compounds from cannabis—CBD and THC—show surprisingly strong effects against ovarian cancer cells. Used together, they slow cell growth, reduce colony formation, an...
www.sciencedaily.com
December 31, 2025 at 1:18 PM
caare.bsky.social
TU Wien and Medical University of Vienna use 3D bioprinting to create human skin models for studying inflammatory diseases without cruel and flawed animal testing. medicalxpress.com/news/2025-12...
3D bioprinting offers alternative to animal testing for skin disease research
At TU Wien, researchers are developing three-dimensional (3D) printing techniques that can be used to create living biological tissue—for example, to study skin diseases.
medicalxpress.com
December 30, 2025 at 4:04 PM
caare.bsky.social
Without using animals, Italian Institute of Technology researchers used AI to design a molecule that boosts chemotherapy response in pancreatic cancer. www.technologynetworks.com/proteomics/n...
AI-Designed Molecule Boosts Chemotherapy Response in Pancreatic Cancer
Researchers at the Italian Institute of Technology developed an AI-designed aptamer that disrupts DNA repair in pancreatic cancer cells. The molecule, Apt1, increases tumor sensitivity to chemotherapy...
www.technologynetworks.com
December 29, 2025 at 1:41 PM
caare.bsky.social
Universität Leipzig researchers studied human patients to show GRIN2A gene variants directly caused psychiatric illness, highlighting human-based science over animal tests.
www.sciencedaily.com/releases/202...
Scientists discover first gene proven to directly cause mental illness
Scientists have discovered that a single gene, GRIN2A, can directly cause mental illness—something previously thought to stem only from many genes acting together. People with certain variants of this...
www.sciencedaily.com
December 26, 2025 at 11:29 AM
caare.bsky.social
King’s College London linked polyphenol-rich diets to better heart health using human data, showing human research can generate insights for disease prevention.
www.sciencedaily.com/releases/202...
Scientists reveal a powerful heart boost hidden in everyday foods
Regular consumption of polyphenol-rich foods like tea, coffee, berries, nuts, and whole grains may significantly support long-term heart health. A decade-long study of more than 3,100 adults found tha...
www.sciencedaily.com
December 26, 2025 at 11:29 AM
caare.bsky.social
Human research by the Psychiatric Genomics Consortium showed 5 genetic clusters explain risk for psychiatric disorders, guiding more accurate treatments than animal tests. www.technologynetworks.com/genomics/new...
Five Genetic Clusters Explain Over Half of All Psychiatric Risk
A massive genomic study of over 1 million cases found that shared risk across 14 psychiatric disorders is reduced to 5 underlying genetic factors. Researchers linked each factor to specific brain cell...
www.technologynetworks.com
December 24, 2025 at 1:36 PM
caare.bsky.social
Cornell researchers show how lab housing constrains mouse behavior. Given space and choice outdoors, mice explored, decided, and engaged with their world.
phys.org/news/2025-12...
From cages to fields: Lab mice lose their anxiety after a week outdoors
When postdoctoral researcher Matthew Zipple releases lab mice into a large, enclosed field just off Cornell's campus, something remarkable happens.
phys.org
December 22, 2025 at 2:12 PM
caare.bsky.social
University of Basel researchers created an animal-free, human bone marrow model that better reflects human biology in blood and drug studies. www.thechemicalengineer.com/news/breakth...
Breakthrough bone marrow model could reduce need for animal testing
RESEARCHERS have replicated the body’s blood-producing system by creating a bone marrow model made entirely from reprogrammed human cells.
www.thechemicalengineer.com
December 19, 2025 at 1:07 PM
caare.bsky.social
Allen Institute scientists tracked immune shifts in rheumatoid arthritis patients years before symptoms emerged, revealing possible biomarkers and early treatment targets.https://www.sciencedaily.com/releases/2025/11/251126095037.htm
December 17, 2025 at 11:33 AM
caare.bsky.social
Penn State College of Medicine developed a smarter genomic tool to understand disease genetics, showing the potential of human-based methods over outdated animal studies. www.technologynetworks.com/genomics/new...
Scientists Built a Smarter Way To Find Genes Linked to Alzheimer’s and ALS
Researchers developed a method that integrates bulk and single-cell data to map how genetic variants influence gene expression across seven brain cell types. The tool identified about 75% more disease...
www.technologynetworks.com
December 16, 2025 at 12:18 PM
caare.bsky.social
UC Riverside created a fully synthetic brain-tissue model using a PEG scaffold, avoiding cruel and unreliable animal products and improving research precision. www.futurity.org/first-synthe...
Team creates first totally synthetic brain tissue model
The new brain tissue model could enable significant advancements in neurological research.
www.futurity.org
December 15, 2025 at 12:09 PM
caare.bsky.social
Arizona State University used human data to link low choline and obesity to early brain damage—a more ethical and scientifically sound method than animal testing. www.sciencedaily.com/releases/202...
A common nutrient deficiency may be silently harming young brains
Scientists studying young adults with obesity discovered early indicators of brain stress that resemble patterns seen in cognitive impairment. The group showed higher inflammation, signs of liver stra...
www.sciencedaily.com
December 12, 2025 at 12:06 PM
caare.bsky.social
A human MRI study at University of Seville links early schizophrenia to brain changes, demonstrating how human research can deliver findings unobtainable from animals.
www.technologynetworks.com/neuroscience...
Early Schizophrenia Leaves a Fingerprint on Brain Structure
Using MRI scans from 352 schizophrenia patients, researchers found widespread reductions in structural similarity across several brain regions. These disruptions tracked with symptom severity, cogniti...
www.technologynetworks.com
December 10, 2025 at 12:13 PM
caare.bsky.social
In animal-free research, Washington State University grew artificial cartilage from stem cells that mimics natural joint properties, advancing human tissue engineering.
www.technologynetworks.com/applied-scie...
Artificial Cartilage Created Using Stem Cells From Bone Marrow
Researchers are working to create an artificial cartilage that resembles natural cartilage, with a recipe that can be adjusted along the way.
www.technologynetworks.com
December 9, 2025 at 12:12 PM
caare.bsky.social
In a human study, University of Gothenburg showed two drugs that can accelerate PFAS elimination in humans—highlighting human-based studies over animal testing. www.technologynetworks.com/analysis/new...
Certain Drugs Eliminate PFAS From the Body Faster
Discover how certain medications can aid in the elimination of PFAS from the body, revealing new avenues for managing this environmental toxin.
www.technologynetworks.com
December 8, 2025 at 12:08 PM
caare.bsky.social
Human-based testing using donated organs kept viable outside the body are part of the new technologies gaining momentum to replace animal testing.
pharmaphorum.com/rd/beyond-an...
Beyond animal testing: How human data trials are reshaping drug development
Researchers are beginning to imagine a future in which development pipelines are more predictive, more efficient, and ultimately more humane.
pharmaphorum.com
December 5, 2025 at 12:06 PM