Byoung-il Bae lab at UConn Health
@byoungilbae.bsky.social
Biology lab studying cerebral cortical development in health, disease, and evolution
www.biorxiv.org/content/10.1...
First preprint from Bae Lab! An autism-linked ASPM variant drives macrocephaly ("large head"), excessive neurogenesis with expanded outer radial glia, brain hyperconnectivity & social-cognitive deficits. Making too many neurons—that alone can be the problem in autism.
First preprint from Bae Lab! An autism-linked ASPM variant drives macrocephaly ("large head"), excessive neurogenesis with expanded outer radial glia, brain hyperconnectivity & social-cognitive deficits. Making too many neurons—that alone can be the problem in autism.
Autism-associated ASPM variant causes macrocephaly and social-cognitive deficits in mice
In autism spectrum disorder (ASD), a neurodevelopmental disorder with social-cognitive deficits, macrocephaly occurs in 20% of patients with severe symptoms. However, the role of macrocephaly in ASD p...
www.biorxiv.org
February 19, 2025 at 5:28 PM
www.biorxiv.org/content/10.1...
First preprint from Bae Lab! An autism-linked ASPM variant drives macrocephaly ("large head"), excessive neurogenesis with expanded outer radial glia, brain hyperconnectivity & social-cognitive deficits. Making too many neurons—that alone can be the problem in autism.
First preprint from Bae Lab! An autism-linked ASPM variant drives macrocephaly ("large head"), excessive neurogenesis with expanded outer radial glia, brain hyperconnectivity & social-cognitive deficits. Making too many neurons—that alone can be the problem in autism.