Brendan Schroyen
brendanschroyen.bsky.social
Brendan Schroyen
@brendanschroyen.bsky.social
🇧🇪🏳️‍🌈 PhD researcher @VUB (Peeters Lab). 🔬🕵️ Molecular biology, haloarchaea, bioplastics.
Reposted by Brendan Schroyen
Tune in for our last (😭) APH session of this semester next WEDNESDAY, May 14th, at 10 AM EST / 4 PM CET!!! Check your email soon for the Zoom link or sign up to join our mailing list here: t.co/b17JFAaZQ6. Check out the exciting talks we have planned for you:
May 8, 2025 at 5:17 PM
May 7, 2025 at 9:57 AM
6/x
A huge thank you to Radwa Moanis, Hannelore Geeraert, Niko Van den Brande, Ulrich Hennecke, Stanislav Obruča, Iva Buchtíková, Karel Sedlář, Petr Sedláček — and of course, Eveline Peeters 😁 — for their expertise, insights, and invaluable contributions to this work!
May 7, 2025 at 9:45 AM
5/x
This opens exciting questions: How do their enzymes and granule structures cope with heat? Could they inspire heat-stable PHA production platforms?

Answering these could push the frontiers and enable next-gen bioplastic production under extreme conditions.

#Extremophiles #Bioplastics
May 7, 2025 at 9:45 AM
4/x
🧪 Limited energy yield in hot, often anaerobic environments?
🧬 Cytoplasmic crowding from PHA granules disrupts molecular diffusion?
💧 Higher risk of water loss and cytoplasmic dehydration?
🌡️ Thermal instability of amorphous PHA granules leads to aggregation or crystallization?
May 7, 2025 at 9:45 AM
3/x
🙋 Why oh why is PHA accumulation such a common strategy in mesophiles and moderate thermophiles but not in extreme thermophiles?
May 7, 2025 at 9:45 AM
2/x
🔥🔥🔥 However, when looking at the genomes of extremely thermophilic microorganisms we found that PHA producers became MUCH scarcer. We couldn't find hits within the bacterial domain and found only a few hits in the archaeal domain belonging to Ferroglobus sp. Archaeoglobus sp. and Geoglobus sp.
May 7, 2025 at 9:45 AM
1/x
🔥 As confirmed in existing literature, we did find a lot of examples of moderately thermophilic microorganisms which can produce PHAs, both in the archaeal and the bacterial domain.
May 7, 2025 at 9:45 AM
🔥📣 New preprint out! So glad to share this chapter of my PhD thesis with the #thermophiles and #polyhydroxyalkanoate community!

⁉️What did we do --> We built a bioinformatics pipeline to scan thermophilic genomes for phaC, the key gene for bioplastic production.
Tracking polyhydroxyalkanoate biosynthesis in thermophilic microorganisms https://www.biorxiv.org/content/10.1101/2025.05.06.652502v1
May 7, 2025 at 9:45 AM
2/x
🔥🔥🔥 However, when looking at the genomes of extremely thermophilic microorganisms we found that PHA producers became MUCH scarcer. We couldn't find hits within the bacterial domain and found only a few hits in the archaeal domain belonging to Ferroglobus sp. Archaeoglobus sp. and Geoglobus sp.
May 7, 2025 at 9:38 AM
1/x
🔥 As confirmed in existing literature, we did find a lot of examples of moderately thermophilic microorganisms which can produce PHAs, both in the archaeal and the bacterial domain.
May 7, 2025 at 9:38 AM
Reposted by Brendan Schroyen
Preprint alert! I’m publishing my last paper from my postdoc work on archaeal cell biology, with @mullinslab.bsky.social, @archaellum.bsky.social, @samjlord.bsky.social, @marleenvw.bsky.social, @arghya93.bsky.social, and more great folks (thread below with more details)
April 16, 2025 at 6:55 PM
Reposted by Brendan Schroyen
It's that time again! Make sure to tune in THIS WEDNESDAY, March 12th, at 11AM EST (note the time change) / 4 PM CET to catch two exciting talks from @cjhines.bsky.social and Priyanka Chatterjee!! Check your email for the Zoom link or visit our website for more info on how to join (link in bio).
March 10, 2025 at 8:34 AM
The chaotic energy we all need on a Friday 😂.
February 21, 2025 at 7:26 AM
Looking forward to the new APH series! Next Wednesday, don't miss out!
Archaea Power Hour is back next week on WEDNESDAY, Feb. 12th at 10 AM EST / 4 PM CET! Make sure to attend and show your love for archaea this coming Valentine's week 😍🥰♥️!!! Join our mailing list to receive the Zoom link: t.co/b17JFAaZQ6.
February 5, 2025 at 6:42 PM
Reposted by Brendan Schroyen
Archaea aficionados around the world, APH is now on BlueSky! Follow us for virtual conference announcements and more 🦠
January 16, 2025 at 4:55 PM