Christine Rabinak, PhD, MBA
@brainsbeesbikes.bsky.social
Interim Associate Dean for Research, Wayne State University Eugene Applebaum College of Pharmacy & Health Sciences
Professor, Pharmacy Practice, Wayne State University
Director, tnp2lab.org
Psychiatric Neuroscience, Cannabinoids, Neuroimaging, Equestrian
Professor, Pharmacy Practice, Wayne State University
Director, tnp2lab.org
Psychiatric Neuroscience, Cannabinoids, Neuroimaging, Equestrian
New from WSU Pharmacy Practice faculty Hannah Ferrari & Amber Martirosov: Pharmacy tech–driven care coordination reduces med errors and improves post-discharge safety.
#PharmacyPractice #PatientSafety
doi.org/10.1093/ajhp...
#PharmacyPractice #PatientSafety
doi.org/10.1093/ajhp...
Piecing together fragmented care: An evaluation of a pharmacy-driven transitions-of-care service
AbstractPurpose. Care fragmentation occurs when patients use multiple providers, health systems, and pharmacies, leading to polypharmacy, potentially inapp
doi.org
October 27, 2025 at 11:13 PM
New from WSU Pharmacy Practice faculty Hannah Ferrari & Amber Martirosov: Pharmacy tech–driven care coordination reduces med errors and improves post-discharge safety.
#PharmacyPractice #PatientSafety
doi.org/10.1093/ajhp...
#PharmacyPractice #PatientSafety
doi.org/10.1093/ajhp...
New from WSU: Liu et al. review key molecular links between steatotic liver disease and cancer, identifying emerging therapeutic targets.
egastroenterology.bmj.com/content/3/3/...
egastroenterology.bmj.com/content/3/3/...
Steatotic liver disease and cancer: from pathogenesis to therapeutic targets
As environmental exposomes are changing with time, so are liver diseases around the globe. Due to an increasing prevalence of overnutrition and sedentary lifestyle in the global population, metabolic ...
egastroenterology.bmj.com
October 27, 2025 at 11:08 PM
New from WSU: Liu et al. review key molecular links between steatotic liver disease and cancer, identifying emerging therapeutic targets.
egastroenterology.bmj.com/content/3/3/...
egastroenterology.bmj.com/content/3/3/...
New from WSU researchers: A call to strengthen outpatient respiratory infection diagnostics to cut antibiotic overuse and improve care.
🔗 doi.org/10.1093/ofid...
🔗 doi.org/10.1093/ofid...
Current Evidence and Gaps for Outpatient Respiratory Tract Infection Diagnostics: A Call to Action
Abstract. Antimicrobial stewardship programs (ASPs) are underrepresented in outpatient settings, where antibiotic use and overprescribing are common. Upper
doi.org
October 27, 2025 at 11:04 PM
New from WSU researchers: A call to strengthen outpatient respiratory infection diagnostics to cut antibiotic overuse and improve care.
🔗 doi.org/10.1093/ofid...
🔗 doi.org/10.1093/ofid...
New from WSU’s College of Pharmacy & Health Sciences: Shortening vancomycin prophylaxis to 72h after lung transplant reduced kidney injury risk without more infections.
🔗 doi.org/10.1111/tid....
🔗 doi.org/10.1111/tid....
Implementation of a Protocol With a Shortened Vancomycin Prophylaxis Duration is Associated With Reduced Acute Kidney Injury in Lung Transplant Recipients: A Quasi‐Experimental Study
We evaluated implementation of a shortened post-operative vancomycin prophylaxis duration protocol on acute kidney injury (AKI) in lung transplant recipients. The intervention, modifying vancomycin (...
doi.org
October 27, 2025 at 11:02 PM
New from WSU’s College of Pharmacy & Health Sciences: Shortening vancomycin prophylaxis to 72h after lung transplant reduced kidney injury risk without more infections.
🔗 doi.org/10.1111/tid....
🔗 doi.org/10.1111/tid....
A new study from Michigan finds that doxyPEP (post-exposure doxycycline) is underused — even in populations at higher risk for bacterial STIs.
🔗 doi.org/10.1177/0956...
#PublicHealth #STIPrevention #Epidemiology
🔗 doi.org/10.1177/0956...
#PublicHealth #STIPrevention #Epidemiology
A cross-sectional analysis of doxyPEP use and outcomes in Michigan, United States - Christen J Arena, Nathan A Everson, Rachel M Kenney, Indira Brar, Smitha Gudipati, Nicholas Yared, Susan L Davis, Mi...
Background: In 2024, national guidance was issued for doxycycline post-exposure prophylaxis (doxy-PEP) to prevent bacterial sexually transmitted infections (STI...
doi.org
October 15, 2025 at 2:29 AM
A new study from Michigan finds that doxyPEP (post-exposure doxycycline) is underused — even in populations at higher risk for bacterial STIs.
🔗 doi.org/10.1177/0956...
#PublicHealth #STIPrevention #Epidemiology
🔗 doi.org/10.1177/0956...
#PublicHealth #STIPrevention #Epidemiology
New collaborative study identifies 4-substituted phenylpyrazolidinone derivatives as potent inhibitors of Ku70/80-DNA-PK, a key enzyme in the DNA repair pathway.
🔗 doi.org/10.1039/d5md...
#MedicinalChemistry #DNARepair #Oncology #Pharmacology
🔗 doi.org/10.1039/d5md...
#MedicinalChemistry #DNARepair #Oncology #Pharmacology
October 15, 2025 at 2:23 AM
New collaborative study identifies 4-substituted phenylpyrazolidinone derivatives as potent inhibitors of Ku70/80-DNA-PK, a key enzyme in the DNA repair pathway.
🔗 doi.org/10.1039/d5md...
#MedicinalChemistry #DNARepair #Oncology #Pharmacology
🔗 doi.org/10.1039/d5md...
#MedicinalChemistry #DNARepair #Oncology #Pharmacology
A short 4–amino acid intracellular motif of the immune checkpoint protein VISTA directly inhibits growth receptor signaling (EGFR/HER2), suppressing tumor growth.
🔗 doi.org/10.1158/0008...
#Oncology #Immunotherapy #CancerBiology
🔗 doi.org/10.1158/0008...
#Oncology #Immunotherapy #CancerBiology
A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
Characterization of the molecular mechanisms of VISTA and elucidation of therapeutic vulnerabilities in a class of triple-negative breast cancer that strongly expresses VISTA in tumor cells could info...
doi.org
October 15, 2025 at 2:17 AM
A short 4–amino acid intracellular motif of the immune checkpoint protein VISTA directly inhibits growth receptor signaling (EGFR/HER2), suppressing tumor growth.
🔗 doi.org/10.1158/0008...
#Oncology #Immunotherapy #CancerBiology
🔗 doi.org/10.1158/0008...
#Oncology #Immunotherapy #CancerBiology
A fast, non-enzymatic thermal method (90 °C for 15 min) efficiently converts the prodrug ceftaroline fosamil (Teflaro®) into its active form.
🔗 doi.org/10.1099/jmm....
#Antibiotics #PharmacyResearch #DrugDiscovery
🔗 doi.org/10.1099/jmm....
#Antibiotics #PharmacyResearch #DrugDiscovery
Rapid deprotection and purification of ceftaroline free base from its phosphoramidate prodrug
Contemporary pharmaceutical design often incorporates functional groups to improve the pharmacokinetic/pharmacodynamic profile of a desired active chemical entity. These compounds are known as prodrug...
doi.org
October 15, 2025 at 2:12 AM
A fast, non-enzymatic thermal method (90 °C for 15 min) efficiently converts the prodrug ceftaroline fosamil (Teflaro®) into its active form.
🔗 doi.org/10.1099/jmm....
#Antibiotics #PharmacyResearch #DrugDiscovery
🔗 doi.org/10.1099/jmm....
#Antibiotics #PharmacyResearch #DrugDiscovery
A clever microbiology nudge—a simple comment added to lab reports—led to a 4.6× increase in use of narrow-spectrum antibiotics for Streptococcus pneumoniae bloodstream infections.
🔗 doi.org/10.1017/ash....
#AntibioticStewardship #BehavioralScience #Microbiology
🔗 doi.org/10.1017/ash....
#AntibioticStewardship #BehavioralScience #Microbiology
A little nudge goes a long way: assessing the impact of a microbiology nudge comment on narrow-spectrum antibiotic use in uncomplicated Streptococcus pneumoniae bloodstream infections | Antimicrobial ...
A little nudge goes a long way: assessing the impact of a microbiology nudge comment on narrow-spectrum antibiotic use in uncomplicated Streptococcus pneumoniae bloodstream infections - Volume 5 Issue...
doi.org
October 15, 2025 at 2:03 AM
A clever microbiology nudge—a simple comment added to lab reports—led to a 4.6× increase in use of narrow-spectrum antibiotics for Streptococcus pneumoniae bloodstream infections.
🔗 doi.org/10.1017/ash....
#AntibioticStewardship #BehavioralScience #Microbiology
🔗 doi.org/10.1017/ash....
#AntibioticStewardship #BehavioralScience #Microbiology
Near-infrared light at 750 & 950 nm reduces mitochondrial hyperactivity and oxidative stress after simulated ischemia/reperfusion.
A simple, non-drug approach that speeds mitochondrial recovery and limits cell death — potential implications for stroke therapy.
🔗 doi.org/10.3390/anti...
A simple, non-drug approach that speeds mitochondrial recovery and limits cell death — potential implications for stroke therapy.
🔗 doi.org/10.3390/anti...
doi.org
October 15, 2025 at 2:00 AM
Near-infrared light at 750 & 950 nm reduces mitochondrial hyperactivity and oxidative stress after simulated ischemia/reperfusion.
A simple, non-drug approach that speeds mitochondrial recovery and limits cell death — potential implications for stroke therapy.
🔗 doi.org/10.3390/anti...
A simple, non-drug approach that speeds mitochondrial recovery and limits cell death — potential implications for stroke therapy.
🔗 doi.org/10.3390/anti...
📚 New in RSAP by Wayne State EACPHS and colleagues: Core journals in #PharmacyPractice—developed using theory + data to define the field’s scholarly boundaries.
A must-read for faculty, editors, & promotion committees.
🔗 doi.org/10.1016/j.sa...
#PharmEd #AcademicPublishing
A must-read for faculty, editors, & promotion committees.
🔗 doi.org/10.1016/j.sa...
#PharmEd #AcademicPublishing
Redirecting
doi.org
September 15, 2025 at 11:54 PM
📚 New in RSAP by Wayne State EACPHS and colleagues: Core journals in #PharmacyPractice—developed using theory + data to define the field’s scholarly boundaries.
A must-read for faculty, editors, & promotion committees.
🔗 doi.org/10.1016/j.sa...
#PharmEd #AcademicPublishing
A must-read for faculty, editors, & promotion committees.
🔗 doi.org/10.1016/j.sa...
#PharmEd #AcademicPublishing
💉 New in JICM: Long-acting insulin does not increase hypoglycemia risk in ICU patients with diabetes.
A promising insight for safe glycemic control during critical illness. 🏥
journals.sagepub.com/doi/10.1177/...
#ICU #PharmacyResearch #DiabetesCare
A promising insight for safe glycemic control during critical illness. 🏥
journals.sagepub.com/doi/10.1177/...
#ICU #PharmacyResearch #DiabetesCare
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
September 15, 2025 at 11:20 PM
💉 New in JICM: Long-acting insulin does not increase hypoglycemia risk in ICU patients with diabetes.
A promising insight for safe glycemic control during critical illness. 🏥
journals.sagepub.com/doi/10.1177/...
#ICU #PharmacyResearch #DiabetesCare
A promising insight for safe glycemic control during critical illness. 🏥
journals.sagepub.com/doi/10.1177/...
#ICU #PharmacyResearch #DiabetesCare
🚨 MDR Gram-negatives?
Aztreonam–avibactam may be the answer.
WSU EACPHS faculty and students review the current evidence in Pharmacotherapy 🧫
🔗 journals.sagepub.com/doi/10.1177/...
#PharmacyResearch #MBL #AntimicrobialStewardship #InfectiousDiseases
Aztreonam–avibactam may be the answer.
WSU EACPHS faculty and students review the current evidence in Pharmacotherapy 🧫
🔗 journals.sagepub.com/doi/10.1177/...
#PharmacyResearch #MBL #AntimicrobialStewardship #InfectiousDiseases
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
September 15, 2025 at 11:01 PM
🚨 MDR Gram-negatives?
Aztreonam–avibactam may be the answer.
WSU EACPHS faculty and students review the current evidence in Pharmacotherapy 🧫
🔗 journals.sagepub.com/doi/10.1177/...
#PharmacyResearch #MBL #AntimicrobialStewardship #InfectiousDiseases
Aztreonam–avibactam may be the answer.
WSU EACPHS faculty and students review the current evidence in Pharmacotherapy 🧫
🔗 journals.sagepub.com/doi/10.1177/...
#PharmacyResearch #MBL #AntimicrobialStewardship #InfectiousDiseases
Burnout to balance 💥💗
Wayne State EACPHS PharmD alumni Drs. Krystle & Josh Raub reflect on their dual-pharmacist life & how they reclaimed joy, purpose, & family.
Read their story: doi.org/10.1093/ajhp...
#Pharmacy #Wellness #CareerBalance
Wayne State EACPHS PharmD alumni Drs. Krystle & Josh Raub reflect on their dual-pharmacist life & how they reclaimed joy, purpose, & family.
Read their story: doi.org/10.1093/ajhp...
#Pharmacy #Wellness #CareerBalance
Burnout to balance: A dual-pharmacist couple’s story of career and family resilience
We first met the summer before starting pharmacy school at the Eugene Applebaum College of Pharmacy and Health Sciences at Wayne State University. Excited
doi.org
September 15, 2025 at 9:47 PM
Burnout to balance 💥💗
Wayne State EACPHS PharmD alumni Drs. Krystle & Josh Raub reflect on their dual-pharmacist life & how they reclaimed joy, purpose, & family.
Read their story: doi.org/10.1093/ajhp...
#Pharmacy #Wellness #CareerBalance
Wayne State EACPHS PharmD alumni Drs. Krystle & Josh Raub reflect on their dual-pharmacist life & how they reclaimed joy, purpose, & family.
Read their story: doi.org/10.1093/ajhp...
#Pharmacy #Wellness #CareerBalance
Wayne State EACPHS applauds Frappa et al.’s sustained impact + calls for next-gen analytics (e.g., DiD, PSM, Bayesian ITS).
Smart stewardship = saved antibiotics, preserved outcomes. 👏
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
#IDPharmD #AntibioticStewardship #InfectiousDiseases #PublicHealth
Smart stewardship = saved antibiotics, preserved outcomes. 👏
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
#IDPharmD #AntibioticStewardship #InfectiousDiseases #PublicHealth
September 15, 2025 at 9:34 PM
Wayne State EACPHS applauds Frappa et al.’s sustained impact + calls for next-gen analytics (e.g., DiD, PSM, Bayesian ITS).
Smart stewardship = saved antibiotics, preserved outcomes. 👏
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
#IDPharmD #AntibioticStewardship #InfectiousDiseases #PublicHealth
Smart stewardship = saved antibiotics, preserved outcomes. 👏
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
#IDPharmD #AntibioticStewardship #InfectiousDiseases #PublicHealth
An EHR-based alert improved adherence to CDC-recommended trichomoniasis therapy. Smart tech, better outcomes. Wayne State EACPHS
pmc.ncbi.nlm.nih.gov/articles/PMC...
#DigitalHealth #PharmacyPractice
pmc.ncbi.nlm.nih.gov/articles/PMC...
#DigitalHealth #PharmacyPractice
Impact of an Interruptive Alert on the Number of Women Receiving CDC-Recommended Therapy for Trichomoniasis
Background: The 2021 Centers of Disease Control and Prevention (CDC) sexually transmitted infection treatment guidelines recommend a 7-day course of metronidazole or single-dose tinidazole for women w...
pmc.ncbi.nlm.nih.gov
September 15, 2025 at 9:25 PM
An EHR-based alert improved adherence to CDC-recommended trichomoniasis therapy. Smart tech, better outcomes. Wayne State EACPHS
pmc.ncbi.nlm.nih.gov/articles/PMC...
#DigitalHealth #PharmacyPractice
pmc.ncbi.nlm.nih.gov/articles/PMC...
#DigitalHealth #PharmacyPractice
Walking forward or backward engages different brain pathways—myelin water imaging at Wayne State EACPHS reveals novel insights in MS.
link.springer.com/article/10.1...
#Neuroscience #MultipleSclerosis
link.springer.com/article/10.1...
#Neuroscience #MultipleSclerosis
Neural correlates of forward and backward walking in MS: insights from myelin water imaging - Experimental Brain Research
Mobility impairments and increased fall risk are common in multiple sclerosis (MS), resulting from myelin degradation in motor pathways. While forward walking is a common mobility assessment, backward...
link.springer.com
September 15, 2025 at 9:09 PM
Walking forward or backward engages different brain pathways—myelin water imaging at Wayne State EACPHS reveals novel insights in MS.
link.springer.com/article/10.1...
#Neuroscience #MultipleSclerosis
link.springer.com/article/10.1...
#Neuroscience #MultipleSclerosis
Re-evaluating duration: For stable cancer patients, short-course antibiotics may reduce side effects without compromising care. Wayne State EACPHS
pmc.ncbi.nlm.nih.gov/articles/PMC...
#InfectionControl #CancerCare
pmc.ncbi.nlm.nih.gov/articles/PMC...
#InfectionControl #CancerCare
Is Shorter Better in Oncology Patients, Too? A Retrospective Cohort Study of Short- Versus Long-Course Antibiotic Therapy for Uncomplicated Infections in Solid Tumor Patients Receiving Care in Ambulat...
This retrospective cohort study evaluated short- versus long-course antibiotics for uncomplicated infections in ambulatory solid tumor patients. Among 303 patients, outcomes were similar between group...
pmc.ncbi.nlm.nih.gov
September 15, 2025 at 9:05 PM
Re-evaluating duration: For stable cancer patients, short-course antibiotics may reduce side effects without compromising care. Wayne State EACPHS
pmc.ncbi.nlm.nih.gov/articles/PMC...
#InfectionControl #CancerCare
pmc.ncbi.nlm.nih.gov/articles/PMC...
#InfectionControl #CancerCare
Starting eravacycline sooner saves lives. This multicenter study led by Wayne State EACPHS shows earlier use improves clinical outcomes in vulnerable patients.
journals.asm.org/doi/10.1128/...
#PharmacyResearch #IDPharmacy
journals.asm.org/doi/10.1128/...
#PharmacyResearch #IDPharmacy
Eravacycline use in immunocompromised patients: multicenter evaluation of timely versus late initiation on clinical outcomes | Microbiology Spectrum
This multicenter, retrospective study evaluates the impact of timely versus late initiation
of eravacycline (ERV) in immunocompromised patients with multidrug-resistant (MDR)
bacterial infections. Imm...
journals.asm.org
September 15, 2025 at 8:32 PM
Starting eravacycline sooner saves lives. This multicenter study led by Wayne State EACPHS shows earlier use improves clinical outcomes in vulnerable patients.
journals.asm.org/doi/10.1128/...
#PharmacyResearch #IDPharmacy
journals.asm.org/doi/10.1128/...
#PharmacyResearch #IDPharmacy
Assessment is more than a checkbox. This research by Wayne State EACPHS and colleagues uncovers how pharmacy faculty interpret COEPA strategies—what’s working, what’s not.
www.ajpe.org/article/S000...
#AcademicMedicine #TeachingExcellence
www.ajpe.org/article/S000...
#AcademicMedicine #TeachingExcellence
Across the Annual Meeting Tables: Evaluating Pharmacy Faculty Members’ Understanding of COEPA Assessment Strategies
To assess pharmacy educators' knowledge and perceptions of Curricular Outcomes and
Entrustable Professional Activities (COEPA) and ACPE Standards 2025 assessment strategies.
www.ajpe.org
September 15, 2025 at 8:29 PM
Assessment is more than a checkbox. This research by Wayne State EACPHS and colleagues uncovers how pharmacy faculty interpret COEPA strategies—what’s working, what’s not.
www.ajpe.org/article/S000...
#AcademicMedicine #TeachingExcellence
www.ajpe.org/article/S000...
#AcademicMedicine #TeachingExcellence
📘 Just published in Brain Sciences by Wayne State EACPHS: MHFA training improves pharmacy students’ & pharmacists’ confidence and mental health literacy.
Training pharmacists to recognize and respond to mental health crises = stronger, safer communities. 💊🧠
pmc.ncbi.nlm.nih.gov/articles/PMC...
Training pharmacists to recognize and respond to mental health crises = stronger, safer communities. 💊🧠
pmc.ncbi.nlm.nih.gov/articles/PMC...
The Effect of Mental Health First Aid Training on Pharmacist and Pharmacy Student Confidence and Knowledge: A Systematic Review and Meta-Analysis
Background/Objectives: Pharmacists are highly accessible healthcare providers who have frequent, repeated contact with diverse patient populations. They are poised to offer expanded and comprehensive ...
pmc.ncbi.nlm.nih.gov
September 15, 2025 at 8:22 PM
📘 Just published in Brain Sciences by Wayne State EACPHS: MHFA training improves pharmacy students’ & pharmacists’ confidence and mental health literacy.
Training pharmacists to recognize and respond to mental health crises = stronger, safer communities. 💊🧠
pmc.ncbi.nlm.nih.gov/articles/PMC...
Training pharmacists to recognize and respond to mental health crises = stronger, safer communities. 💊🧠
pmc.ncbi.nlm.nih.gov/articles/PMC...
Not all anemia needs iron.
Talzenna® suppresses bone marrow → fewer red blood cells, even when iron is normal.
Supportive care = transfusions, not iron pills.
#Oncology #PharmacyEducation #Talzenna #Pharmacology #AnemiaAwareness
Talzenna® suppresses bone marrow → fewer red blood cells, even when iron is normal.
Supportive care = transfusions, not iron pills.
#Oncology #PharmacyEducation #Talzenna #Pharmacology #AnemiaAwareness
September 13, 2025 at 6:44 AM
Not all anemia needs iron.
Talzenna® suppresses bone marrow → fewer red blood cells, even when iron is normal.
Supportive care = transfusions, not iron pills.
#Oncology #PharmacyEducation #Talzenna #Pharmacology #AnemiaAwareness
Talzenna® suppresses bone marrow → fewer red blood cells, even when iron is normal.
Supportive care = transfusions, not iron pills.
#Oncology #PharmacyEducation #Talzenna #Pharmacology #AnemiaAwareness
🦠 Overusing vancomycin in pneumonia treatment?
A study co-authored by WSU EACPHS shows that MRSA nasal PCR testing shortens vancomycin duration more effectively than culture-based methods—supporting better antibiotic stewardship.
doi.org/10.1177/8755...
#MRSA #Vancomycin #InfectiousDiseases
A study co-authored by WSU EACPHS shows that MRSA nasal PCR testing shortens vancomycin duration more effectively than culture-based methods—supporting better antibiotic stewardship.
doi.org/10.1177/8755...
#MRSA #Vancomycin #InfectiousDiseases
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
doi.org
August 29, 2025 at 10:01 PM
🦠 Overusing vancomycin in pneumonia treatment?
A study co-authored by WSU EACPHS shows that MRSA nasal PCR testing shortens vancomycin duration more effectively than culture-based methods—supporting better antibiotic stewardship.
doi.org/10.1177/8755...
#MRSA #Vancomycin #InfectiousDiseases
A study co-authored by WSU EACPHS shows that MRSA nasal PCR testing shortens vancomycin duration more effectively than culture-based methods—supporting better antibiotic stewardship.
doi.org/10.1177/8755...
#MRSA #Vancomycin #InfectiousDiseases
🧬 Curious how CRISPR/Cas9 could transform cancer therapy?
This review led by WSU EACPHS dives deep into nanotech delivery strategies—lipid NPs, exosomes, polymers—to target cancer cells with gene-editing precision.
doi.org/10.3390/cell...
#CRISPR #CancerResearch #Nanotechnology #WayneState
This review led by WSU EACPHS dives deep into nanotech delivery strategies—lipid NPs, exosomes, polymers—to target cancer cells with gene-editing precision.
doi.org/10.3390/cell...
#CRISPR #CancerResearch #Nanotechnology #WayneState
doi.org
August 29, 2025 at 9:36 PM
🧬 Curious how CRISPR/Cas9 could transform cancer therapy?
This review led by WSU EACPHS dives deep into nanotech delivery strategies—lipid NPs, exosomes, polymers—to target cancer cells with gene-editing precision.
doi.org/10.3390/cell...
#CRISPR #CancerResearch #Nanotechnology #WayneState
This review led by WSU EACPHS dives deep into nanotech delivery strategies—lipid NPs, exosomes, polymers—to target cancer cells with gene-editing precision.
doi.org/10.3390/cell...
#CRISPR #CancerResearch #Nanotechnology #WayneState
🧠 A new dual-action therapeutic candidate for Parkinson’s?
D-583, developed by WSU EACPHS, is a dopamine agonist that selectively chelates Fe(II) and protects neurons from ferroptosis.
Published in Neurochemical Research
🔗 doi.org/10.1007/s110...
#Parkinsons #Ferroptosis #Neuroprotective
D-583, developed by WSU EACPHS, is a dopamine agonist that selectively chelates Fe(II) and protects neurons from ferroptosis.
Published in Neurochemical Research
🔗 doi.org/10.1007/s110...
#Parkinsons #Ferroptosis #Neuroprotective
Biological Characterization of the Anti-ferroptotic Properties of a Novel Anti-Parkinsonian Iron (II) Selective Dopamine Agonist, D-583 - Neurochemical Research
Here, we report the in vitro and in vivo characterization of a novel hybrid D2/D3 agonist and iron (II)-specific chelator, D-583, as a multi-target-directed ligand for Parkinson’s disease (PD). In our...
doi.org
August 29, 2025 at 9:17 PM
🧠 A new dual-action therapeutic candidate for Parkinson’s?
D-583, developed by WSU EACPHS, is a dopamine agonist that selectively chelates Fe(II) and protects neurons from ferroptosis.
Published in Neurochemical Research
🔗 doi.org/10.1007/s110...
#Parkinsons #Ferroptosis #Neuroprotective
D-583, developed by WSU EACPHS, is a dopamine agonist that selectively chelates Fe(II) and protects neurons from ferroptosis.
Published in Neurochemical Research
🔗 doi.org/10.1007/s110...
#Parkinsons #Ferroptosis #Neuroprotective