Job Boekhoven
@boekhovenlab.bsky.social
Prof. In Systems Chemistry trying synthesize life
Pinned
Job Boekhoven
@boekhovenlab.bsky.social
· Nov 22
Accepted! Soon, in your favorite American chemistry journal🥳!
Reposted by Job Boekhoven
I’m happy to share Hector Soria Carrera and Leonie Kauling’s recent work in Chem by @cellpress.bsky.social!
A 🧵 below:
www.cell.com/chem/fulltex...
A 🧵 below:
www.cell.com/chem/fulltex...
Primitive genotype-phenotype coupling in fuel-dependent synthetic cells with an autocatalyst
A challenge in the de novo synthesis of life is coupling genotype with phenotype.
To achieve this, we use fuel-dependent synthetic cells that host a low-fidelity replicator.
This replicator increases ...
www.cell.com
November 11, 2025 at 8:31 AM
I’m happy to share Hector Soria Carrera and Leonie Kauling’s recent work in Chem by @cellpress.bsky.social!
A 🧵 below:
www.cell.com/chem/fulltex...
A 🧵 below:
www.cell.com/chem/fulltex...
Reposted by Job Boekhoven
Active droplets are fundamental in cell biology and origin of life. With Jonathan Bauermann, @boekhovenlab.bsky.social, Frank Jülicher, and @m-pol.bsky.social, we show that a critical transition influences their size, morphology, ripening and division propensity
journals.aps.org/prx/abstract...
journals.aps.org/prx/abstract...
November 15, 2025 at 11:28 AM
Active droplets are fundamental in cell biology and origin of life. With Jonathan Bauermann, @boekhovenlab.bsky.social, Frank Jülicher, and @m-pol.bsky.social, we show that a critical transition influences their size, morphology, ripening and division propensity
journals.aps.org/prx/abstract...
journals.aps.org/prx/abstract...
I’m happy to share Hector Soria Carrera and Leonie Kauling’s recent work in Chem by @cellpress.bsky.social!
A 🧵 below:
www.cell.com/chem/fulltex...
A 🧵 below:
www.cell.com/chem/fulltex...
Primitive genotype-phenotype coupling in fuel-dependent synthetic cells with an autocatalyst
A challenge in the de novo synthesis of life is coupling genotype with phenotype.
To achieve this, we use fuel-dependent synthetic cells that host a low-fidelity replicator.
This replicator increases ...
www.cell.com
November 11, 2025 at 8:31 AM
I’m happy to share Hector Soria Carrera and Leonie Kauling’s recent work in Chem by @cellpress.bsky.social!
A 🧵 below:
www.cell.com/chem/fulltex...
A 🧵 below:
www.cell.com/chem/fulltex...
I am over the moon! Thank you so much @rsc-masc.bsky.social! Our work has been a group effort by the entire BoekhovenLab and alumni!
📣 Announcement 📣
We are delighted to announce that the 2025 Supramolecular Chemistry Award 🏆 goes to Prof Dr Job Boekhoven from TU Munich.
Congratulations, Job! @boekhovenlab.bsky.social
Thanks @cellpress.bsky.social for generously sponsoring the award!
(1/3)
We are delighted to announce that the 2025 Supramolecular Chemistry Award 🏆 goes to Prof Dr Job Boekhoven from TU Munich.
Congratulations, Job! @boekhovenlab.bsky.social
Thanks @cellpress.bsky.social for generously sponsoring the award!
(1/3)
November 6, 2025 at 4:13 PM
I am over the moon! Thank you so much @rsc-masc.bsky.social! Our work has been a group effort by the entire BoekhovenLab and alumni!
Freshly published: "Primitive genotype-phenotype coupling in fuel-dependent synthetic cells"
Amazing work and a critical step towards synthetic life by Hector Soria and Leonie Kauling. A thread will follow soon:
t.co/9LfrnVYzoq
Amazing work and a critical step towards synthetic life by Hector Soria and Leonie Kauling. A thread will follow soon:
t.co/9LfrnVYzoq
November 6, 2025 at 10:06 AM
Freshly published: "Primitive genotype-phenotype coupling in fuel-dependent synthetic cells"
Amazing work and a critical step towards synthetic life by Hector Soria and Leonie Kauling. A thread will follow soon:
t.co/9LfrnVYzoq
Amazing work and a critical step towards synthetic life by Hector Soria and Leonie Kauling. A thread will follow soon:
t.co/9LfrnVYzoq
Reposted by Job Boekhoven
How to build life from non-living components? Or perhaps a blueprint of #MatterToLife!
syntheticcell.eu/a-recipe-for...
Check out the recent study from @boekhovenlab.bsky.social and @hniederho.bsky.social, @tum.de
www.cell.com/chem/fulltex...
syntheticcell.eu/a-recipe-for...
Check out the recent study from @boekhovenlab.bsky.social and @hniederho.bsky.social, @tum.de
www.cell.com/chem/fulltex...
A recipe for synthetic cells: non-biological components, a pinch of evolution and then... life?
The Boekhoven Lab recently engineered a cell-like system capable of producing offspring, a key prerequisite for Darwinian evolution.
syntheticcell.eu
July 25, 2025 at 4:51 PM
How to build life from non-living components? Or perhaps a blueprint of #MatterToLife!
syntheticcell.eu/a-recipe-for...
Check out the recent study from @boekhovenlab.bsky.social and @hniederho.bsky.social, @tum.de
www.cell.com/chem/fulltex...
syntheticcell.eu/a-recipe-for...
Check out the recent study from @boekhovenlab.bsky.social and @hniederho.bsky.social, @tum.de
www.cell.com/chem/fulltex...
Reposted by Job Boekhoven
The @boekhovenlab.bsky.social aims to build life from non-living components using #evolution. We look back at one of the group's recent results: the engineering of cell-like systems capable of producing offspring, a key prerequisite for Darwinian evolution
#syncell
syntheticcell.eu/a-recipe-for...
#syncell
syntheticcell.eu/a-recipe-for...
A recipe for synthetic cells: non-biological components, a pinch of evolution and then... life?
The Boekhoven Lab recently engineered a cell-like system capable of producing offspring, a key prerequisite for Darwinian evolution.
syntheticcell.eu
July 28, 2025 at 9:41 AM
The @boekhovenlab.bsky.social aims to build life from non-living components using #evolution. We look back at one of the group's recent results: the engineering of cell-like systems capable of producing offspring, a key prerequisite for Darwinian evolution
#syncell
syntheticcell.eu/a-recipe-for...
#syncell
syntheticcell.eu/a-recipe-for...
Reposted by Job Boekhoven
🗣️ @boekhovenlab.bsky.social is Associate Professor in the Bioscience Department at the @tumunich.bsky.social 🇩🇪
🎯 His research focuses on #molecular #selfassembly and #non-#equilibrium #chemically fueled #supramolecular #assemblies towards #synthetic #life from the bottom up 👌
👉 Do not miss it!
🎯 His research focuses on #molecular #selfassembly and #non-#equilibrium #chemically fueled #supramolecular #assemblies towards #synthetic #life from the bottom up 👌
👉 Do not miss it!
June 6, 2025 at 1:09 PM
🗣️ @boekhovenlab.bsky.social is Associate Professor in the Bioscience Department at the @tumunich.bsky.social 🇩🇪
🎯 His research focuses on #molecular #selfassembly and #non-#equilibrium #chemically fueled #supramolecular #assemblies towards #synthetic #life from the bottom up 👌
👉 Do not miss it!
🎯 His research focuses on #molecular #selfassembly and #non-#equilibrium #chemically fueled #supramolecular #assemblies towards #synthetic #life from the bottom up 👌
👉 Do not miss it!
Reposted by Job Boekhoven
Pumping molecules against a gradient without a pump?
Back-to-back with @boekhovenlab.bsky.social, we describe minimal systems that use chemical energy to transport molecules against a concentration gradient.
It started with a little shock!🧵
Us: shorturl.at/smQNF
Job's team: shorturl.at/zftps
Back-to-back with @boekhovenlab.bsky.social, we describe minimal systems that use chemical energy to transport molecules against a concentration gradient.
It started with a little shock!🧵
Us: shorturl.at/smQNF
Job's team: shorturl.at/zftps
June 5, 2025 at 4:19 PM
Pumping molecules against a gradient without a pump?
Back-to-back with @boekhovenlab.bsky.social, we describe minimal systems that use chemical energy to transport molecules against a concentration gradient.
It started with a little shock!🧵
Us: shorturl.at/smQNF
Job's team: shorturl.at/zftps
Back-to-back with @boekhovenlab.bsky.social, we describe minimal systems that use chemical energy to transport molecules against a concentration gradient.
It started with a little shock!🧵
Us: shorturl.at/smQNF
Job's team: shorturl.at/zftps
Check out Monika's work published in @cp-chem.bsky.social!
We’ve engineered synthetic cells that emerge, grow, and produce offspring autonomously, powered by chemical fuel. A significant stride towards synthetic life!
www.sciencedirect.com/science/arti...
We’ve engineered synthetic cells that emerge, grow, and produce offspring autonomously, powered by chemical fuel. A significant stride towards synthetic life!
www.sciencedirect.com/science/arti...
May 30, 2025 at 9:53 AM
Check out Monika's work published in @cp-chem.bsky.social!
We’ve engineered synthetic cells that emerge, grow, and produce offspring autonomously, powered by chemical fuel. A significant stride towards synthetic life!
www.sciencedirect.com/science/arti...
We’ve engineered synthetic cells that emerge, grow, and produce offspring autonomously, powered by chemical fuel. A significant stride towards synthetic life!
www.sciencedirect.com/science/arti...
How can a cell control the size of its organelles?
Excited to share a mechanism to control droplet size we recently found.
a 🧵
www.nature.com/articles/s41...
Excited to share a mechanism to control droplet size we recently found.
a 🧵
www.nature.com/articles/s41...
April 25, 2025 at 12:32 PM
How can a cell control the size of its organelles?
Excited to share a mechanism to control droplet size we recently found.
a 🧵
www.nature.com/articles/s41...
Excited to share a mechanism to control droplet size we recently found.
a 🧵
www.nature.com/articles/s41...
Reposted by Job Boekhoven
Our group Mesoscopic Physics of Life is now on BlueSky. Hopefully no more strange and unwanted messages ... 😆
March 19, 2025 at 6:45 AM
Our group Mesoscopic Physics of Life is now on BlueSky. Hopefully no more strange and unwanted messages ... 😆
Reposted by Job Boekhoven
Our university is among the top 20 universities in the world for the first time in both #NaturalSciences and #engineering & #technology in the QS World University Rankings by Subject: go.tum.de/639382 🎉
#QSWUR #SubjectRankings #HigherEducation
📷A. Eckert
#QSWUR #SubjectRankings #HigherEducation
📷A. Eckert
TUM among the top 20 worldwide in natural sciences and engineering
In the QS World University Rankings by Subject, TUM is among the top 20 universities in both natural sciences and engineering & technology.
go.tum.de
March 12, 2025 at 2:55 PM
Our university is among the top 20 universities in the world for the first time in both #NaturalSciences and #engineering & #technology in the QS World University Rankings by Subject: go.tum.de/639382 🎉
#QSWUR #SubjectRankings #HigherEducation
📷A. Eckert
#QSWUR #SubjectRankings #HigherEducation
📷A. Eckert
Reposted by Job Boekhoven
#JungesKolleg: Die neuen Mitglieder stehen fest!
Christoph Heilig @lmumuenchen.bsky.social, Maik Luu @Uniklinik Würzburg, Carolin Müller @fau.de, Robert J. Mayer @tum.de und Charlotte Wendland @lmumuenchen.bsky.social
👉 tiny.badw.de/rPTXJE
Willkommen in der BAdW!
Foto: @wolf-bild.bsky.social
Christoph Heilig @lmumuenchen.bsky.social, Maik Luu @Uniklinik Würzburg, Carolin Müller @fau.de, Robert J. Mayer @tum.de und Charlotte Wendland @lmumuenchen.bsky.social
👉 tiny.badw.de/rPTXJE
Willkommen in der BAdW!
Foto: @wolf-bild.bsky.social
February 28, 2025 at 10:47 AM
#JungesKolleg: Die neuen Mitglieder stehen fest!
Christoph Heilig @lmumuenchen.bsky.social, Maik Luu @Uniklinik Würzburg, Carolin Müller @fau.de, Robert J. Mayer @tum.de und Charlotte Wendland @lmumuenchen.bsky.social
👉 tiny.badw.de/rPTXJE
Willkommen in der BAdW!
Foto: @wolf-bild.bsky.social
Christoph Heilig @lmumuenchen.bsky.social, Maik Luu @Uniklinik Würzburg, Carolin Müller @fau.de, Robert J. Mayer @tum.de und Charlotte Wendland @lmumuenchen.bsky.social
👉 tiny.badw.de/rPTXJE
Willkommen in der BAdW!
Foto: @wolf-bild.bsky.social
Check out the video highlight of our recent work! youtube.com/shorts/MCJEb...
It looks like life, but… | Headline Science
YouTube video by American Chemical Society
youtube.com
February 27, 2025 at 9:23 AM
Check out the video highlight of our recent work! youtube.com/shorts/MCJEb...
It’s out!😃
2 years ago, I organized a workshop with @WebersGroup and @KGoepfrich on how to build Life.
We discussed with leading scientists by day and wrote up our discussions in the eves.
The "Roadmap Towards Synthetic Life" is now out in Chem!
www.sciencedirect.com/science/arti...
2 years ago, I organized a workshop with @WebersGroup and @KGoepfrich on how to build Life.
We discussed with leading scientists by day and wrote up our discussions in the eves.
The "Roadmap Towards Synthetic Life" is now out in Chem!
www.sciencedirect.com/science/arti...
A roadmap toward the synthesis of life
The synthesis of life from non-living matter has captivated and divided scientists for centuries. This bold goal aims at unraveling the fundamental pr…
www.sciencedirect.com
February 7, 2025 at 8:56 AM
It’s out!😃
2 years ago, I organized a workshop with @WebersGroup and @KGoepfrich on how to build Life.
We discussed with leading scientists by day and wrote up our discussions in the eves.
The "Roadmap Towards Synthetic Life" is now out in Chem!
www.sciencedirect.com/science/arti...
2 years ago, I organized a workshop with @WebersGroup and @KGoepfrich on how to build Life.
We discussed with leading scientists by day and wrote up our discussions in the eves.
The "Roadmap Towards Synthetic Life" is now out in Chem!
www.sciencedirect.com/science/arti...
Just arrived in the beautiful Tarragona. Excited to give a lecture at the amazing ICIQ tomorrow. iciq.org/event/regula...
Regulating molecular assembly with chemical fuels— Spinning ribbons, dissipative structures, and an approach towards synthetic life - ICIQ
iciq.org
February 5, 2025 at 6:30 PM
Just arrived in the beautiful Tarragona. Excited to give a lecture at the amazing ICIQ tomorrow. iciq.org/event/regula...
Excited to give a lecture this Friday at the University of Barcelona. More info here:
dqio.ub.edu
dqio.ub.edu
February 5, 2025 at 2:19 PM
Excited to give a lecture this Friday at the University of Barcelona. More info here:
dqio.ub.edu
dqio.ub.edu
Reposted by Job Boekhoven
📣Open Call for Fellowships: International scientists who would like to work closely with scientists @tumuenchen.bsky.social and visit us for extend periods can still be nominated until 18 February!
More information: ias.tum.de/ias/programs...
Open Call: ias.tum.de/ias/news-eve...
More information: ias.tum.de/ias/programs...
Open Call: ias.tum.de/ias/news-eve...
January 9, 2025 at 2:09 PM
📣Open Call for Fellowships: International scientists who would like to work closely with scientists @tumuenchen.bsky.social and visit us for extend periods can still be nominated until 18 February!
More information: ias.tum.de/ias/programs...
Open Call: ias.tum.de/ias/news-eve...
More information: ias.tum.de/ias/programs...
Open Call: ias.tum.de/ias/news-eve...
Reposted by Job Boekhoven
This week's #WednesdayCoffeeTalk: “Converting chemical energy into motion” by @boekhovenlab.bsky.social!
Online at 1 pm - DM us for Zoom info!
ias.tum.de/ias/news-eve...
Online at 1 pm - DM us for Zoom info!
ias.tum.de/ias/news-eve...
December 9, 2024 at 12:39 PM
This week's #WednesdayCoffeeTalk: “Converting chemical energy into motion” by @boekhovenlab.bsky.social!
Online at 1 pm - DM us for Zoom info!
ias.tum.de/ias/news-eve...
Online at 1 pm - DM us for Zoom info!
ias.tum.de/ias/news-eve...
All the hard work done by @pablozambrano.bsky.social!
Now published in JACS! Pablo found an easy way to divide fatty acid-based protocells.
Simplicity first: All you need is to add carbodiimide as fuel!
pubs.acs.org/doi/full/10....
Simplicity first: All you need is to add carbodiimide as fuel!
pubs.acs.org/doi/full/10....
December 4, 2024 at 1:02 PM
All the hard work done by @pablozambrano.bsky.social!
Now published in JACS! Pablo found an easy way to divide fatty acid-based protocells.
Simplicity first: All you need is to add carbodiimide as fuel!
pubs.acs.org/doi/full/10....
Simplicity first: All you need is to add carbodiimide as fuel!
pubs.acs.org/doi/full/10....
December 4, 2024 at 11:24 AM
Now published in JACS! Pablo found an easy way to divide fatty acid-based protocells.
Simplicity first: All you need is to add carbodiimide as fuel!
pubs.acs.org/doi/full/10....
Simplicity first: All you need is to add carbodiimide as fuel!
pubs.acs.org/doi/full/10....
Reposted by Job Boekhoven
I am excited to share our latest publication in JACS: "Chemically Driven Division of Protocells by Membrane Budding"
I am grateful to all my amazing coauthors for their incredible teamwork @boekhovenlab.bsky.social
Read it: pubs.acs.org/doi/10.1021/...
#protocells #chemistry #originoflife #JACS
I am grateful to all my amazing coauthors for their incredible teamwork @boekhovenlab.bsky.social
Read it: pubs.acs.org/doi/10.1021/...
#protocells #chemistry #originoflife #JACS
November 29, 2024 at 8:19 PM
I am excited to share our latest publication in JACS: "Chemically Driven Division of Protocells by Membrane Budding"
I am grateful to all my amazing coauthors for their incredible teamwork @boekhovenlab.bsky.social
Read it: pubs.acs.org/doi/10.1021/...
#protocells #chemistry #originoflife #JACS
I am grateful to all my amazing coauthors for their incredible teamwork @boekhovenlab.bsky.social
Read it: pubs.acs.org/doi/10.1021/...
#protocells #chemistry #originoflife #JACS
Reposted by Job Boekhoven
We are looking for two #postdocs to join us: 1) @ERC_Research funded position in the context of RNA origami, cryoEM, synthetic cells, directed evolution; 2) A position in the excellence cluster @Cluster3DMM2O at the interface of chemistry & biology. Please share and get in touch!
November 20, 2024 at 4:25 PM
We are looking for two #postdocs to join us: 1) @ERC_Research funded position in the context of RNA origami, cryoEM, synthetic cells, directed evolution; 2) A position in the excellence cluster @Cluster3DMM2O at the interface of chemistry & biology. Please share and get in touch!
Reposted by Job Boekhoven
Last year we met with about 60 scientists for 2 weeks to discuss what it means to synthesize life. Here is the summary of our discussion: https://chemrxiv.org/engage/chemrxiv/article-details/668b9aaf01103d79c55e9fab We hope it represents diverse views and serves as a roadmap towards...
A roadmap towards the synthesis of Life
The synthesis of life from non-living matter has captivat...
chemrxiv.org
November 20, 2024 at 4:13 PM
Last year we met with about 60 scientists for 2 weeks to discuss what it means to synthesize life. Here is the summary of our discussion: https://chemrxiv.org/engage/chemrxiv/article-details/668b9aaf01103d79c55e9fab We hope it represents diverse views and serves as a roadmap towards...