Manchester Centre for Biological Timing
@biologicaltimemcr.bsky.social
The University of Manchester is home to the largest biological timing research community in Europe. We bring together world-leading researchers with a multidisciplinary approach to cellular timers and circadian clocks.
On BBC radio 4,Dr Gareth Kitchen shared with us insights on his latest publication in Anaesthesia: www.bbc.co.uk/sounds/play/...
Today - 10/01/2026 - BBC Sounds
Including Sports Desk, Weather and Thought for the Day.
www.bbc.co.uk
February 2, 2026 at 4:42 PM
On BBC radio 4,Dr Gareth Kitchen shared with us insights on his latest publication in Anaesthesia: www.bbc.co.uk/sounds/play/...
New publication for the CfTB!
Time of day of cardiac surgery and postoperative outcomes in the UK: a secondary analysis of linked national datasets
associationofanaesthetists-publications.onlinelibrary.wiley.com/share/VKP7YS...
Time of day of cardiac surgery and postoperative outcomes in the UK: a secondary analysis of linked national datasets
associationofanaesthetists-publications.onlinelibrary.wiley.com/share/VKP7YS...
Time of day of cardiac surgery and postoperative outcomes in the UK: a secondary analysis of linked national datasets
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associationofanaesthetists-publications.onlinelibrary.wiley.com
February 2, 2026 at 4:31 PM
New publication for the CfTB!
Time of day of cardiac surgery and postoperative outcomes in the UK: a secondary analysis of linked national datasets
associationofanaesthetists-publications.onlinelibrary.wiley.com/share/VKP7YS...
Time of day of cardiac surgery and postoperative outcomes in the UK: a secondary analysis of linked national datasets
associationofanaesthetists-publications.onlinelibrary.wiley.com/share/VKP7YS...
Reposted by Manchester Centre for Biological Timing
A new paper from my lab. I will have a full description soon. rdcu.be/eX1Ld
ipRGC properties prevent light from shifting the SCN clock during daytime
Nature - The inability of intrinsically photosensitive retinal ganglion cells to shift the circadian clock in the suprachiasmatic nucleus during daytime is caused by light-dependent depolarization...
rdcu.be
January 7, 2026 at 5:17 PM
A new paper from my lab. I will have a full description soon. rdcu.be/eX1Ld
Wishing the international circadian community a Happy New Year! 🌍⏰ May your 2026 be filled with stable rhythms, bright zeitgebers, and groundbreaking discoveries. Here’s to another 365 cycles together! 🥂 #Chronobiology #CircadianRhythms
January 5, 2026 at 9:56 AM
Wishing the international circadian community a Happy New Year! 🌍⏰ May your 2026 be filled with stable rhythms, bright zeitgebers, and groundbreaking discoveries. Here’s to another 365 cycles together! 🥂 #Chronobiology #CircadianRhythms
Registration is open for the SRBR 2026 Biennial Meeting to take place on May 9-13, 2026 - Amelia Island, FL.
Early career scientists and PhD students are encouraged to apply. Share you discoveries!
srbr.societyconference.com/v2/
Early career scientists and PhD students are encouraged to apply. Share you discoveries!
srbr.societyconference.com/v2/
Conference Home Page
srbr.societyconference.com
November 27, 2025 at 11:12 AM
Registration is open for the SRBR 2026 Biennial Meeting to take place on May 9-13, 2026 - Amelia Island, FL.
Early career scientists and PhD students are encouraged to apply. Share you discoveries!
srbr.societyconference.com/v2/
Early career scientists and PhD students are encouraged to apply. Share you discoveries!
srbr.societyconference.com/v2/
The CfBT welcomes Eder Zavala @ederzavala.bsky.social as a new PI! Eder is a UKRI Future Leaders Fellow; his group’s research lies at the interface of mathematics, physiology, and medicine, using quantitative models and data-driven approaches to reveal how hormonal dynamics shape human health.
November 25, 2025 at 10:10 AM
The CfBT welcomes Eder Zavala @ederzavala.bsky.social as a new PI! Eder is a UKRI Future Leaders Fellow; his group’s research lies at the interface of mathematics, physiology, and medicine, using quantitative models and data-driven approaches to reveal how hormonal dynamics shape human health.
New database of c-Fos Circadian Expression in Whole Mouse Brain by Hiroki Ueda, to use at will and freely! circadian.cfosdb.systems-based-medicine.org/database/
Home
circadian.cfosdb.systems-based-medicine.org
November 20, 2025 at 6:04 PM
New database of c-Fos Circadian Expression in Whole Mouse Brain by Hiroki Ueda, to use at will and freely! circadian.cfosdb.systems-based-medicine.org/database/
Reposted by Manchester Centre for Biological Timing
💡Need more light science in your life?💡
🚨Check out Daylight Awareness Week 3-7 November 2025 by the Daylight Academy!
🌟This year’s Daylight Awareness Week explores how daylight can help build healthier, more sustainable, and fairer societies
daylight.academy/daylight-awa...
🚨Check out Daylight Awareness Week 3-7 November 2025 by the Daylight Academy!
🌟This year’s Daylight Awareness Week explores how daylight can help build healthier, more sustainable, and fairer societies
daylight.academy/daylight-awa...
Daylight Awareness Week 2025 - Daylight Academy
3-7 November 2025 Celebrate daylight with us!
daylight.academy
November 3, 2025 at 7:08 PM
💡Need more light science in your life?💡
🚨Check out Daylight Awareness Week 3-7 November 2025 by the Daylight Academy!
🌟This year’s Daylight Awareness Week explores how daylight can help build healthier, more sustainable, and fairer societies
daylight.academy/daylight-awa...
🚨Check out Daylight Awareness Week 3-7 November 2025 by the Daylight Academy!
🌟This year’s Daylight Awareness Week explores how daylight can help build healthier, more sustainable, and fairer societies
daylight.academy/daylight-awa...
Reposted by Manchester Centre for Biological Timing
☀️ Exciting developments coming soon from SLRCH for our early career folks! Stay tuned! ☀️
November 20, 2025 at 5:23 PM
☀️ Exciting developments coming soon from SLRCH for our early career folks! Stay tuned! ☀️
@airwayamlan.bsky.social will give a seminar at Pints with Parse on the 20th November, speaking about biological timing and asthma! More details at resources.parsebiosciences.com/pints-with-p...
Pints with Parse Manchester
Join Parse Biosciences for a happy hour networking event at Victoria Baths in Manchester.
resources.parsebiosciences.com
November 11, 2025 at 4:05 PM
@airwayamlan.bsky.social will give a seminar at Pints with Parse on the 20th November, speaking about biological timing and asthma! More details at resources.parsebiosciences.com/pints-with-p...
Dr Hannah Durrington @h_durrington is featured in a film made by Asthma and Lung UK about time of day in asthma diagnosis and treatment! Watch at:
vimeo.com/1117260180/0...
vimeo.com/1117260180/0...
Hannah Durrington_9x16 Social_FINAL
This is "Hannah Durrington_9x16 Social_FINAL" by Asthma + Lung UK on Vimeo, the home for high quality videos and the people who love them.
vimeo.com
September 16, 2025 at 2:06 PM
Dr Hannah Durrington @h_durrington is featured in a film made by Asthma and Lung UK about time of day in asthma diagnosis and treatment! Watch at:
vimeo.com/1117260180/0...
vimeo.com/1117260180/0...
12 CfBT representatives and associates presented talks and posters at the European Biological Rhythms Society 2025 congress
ebrs-online.org/index.php/ev...
ebrs-online.org/index.php/ev...
September 1, 2025 at 6:26 AM
12 CfBT representatives and associates presented talks and posters at the European Biological Rhythms Society 2025 congress
ebrs-online.org/index.php/ev...
ebrs-online.org/index.php/ev...
Rob Lucas, Bea Bano Otalora and Tim Brown recipients of a Wellcome Trust Discovery award to study the mechanisms by which light across daytime shapes daily profiles of sleep and influences the circadian clock!
August 12, 2025 at 3:19 PM
Rob Lucas, Bea Bano Otalora and Tim Brown recipients of a Wellcome Trust Discovery award to study the mechanisms by which light across daytime shapes daily profiles of sleep and influences the circadian clock!
New preprint from our CfBT! Congratulation to Jafar, who defended his thesis back in May!
doi.org/10.1101/2025...
doi.org/10.1101/2025...
The club cell circadian clock regulates temporal patterns in leukocyte trafficking in chronic allergic airways disease
Rationale: Asthma displays temporally variable symptoms which worsen overnight, corresponding with a nocturnal increase in airway eosinophils. The molecular clock within the club cell of the bronchial...
doi.org
August 11, 2025 at 4:50 PM
New preprint from our CfBT! Congratulation to Jafar, who defended his thesis back in May!
doi.org/10.1101/2025...
doi.org/10.1101/2025...
New paper from our CfBT! Congratulations to Jess Treeby, second year PhD student!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Guanine is an inhibitor of c-jun terminal kinases - Scientific Reports
Scientific Reports - Guanine is an inhibitor of c-jun terminal kinases
www.nature.com
August 11, 2025 at 4:33 PM
New paper from our CfBT! Congratulations to Jess Treeby, second year PhD student!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
New exciting preprint from our CfBT and associates!
Guanine is an inhibitor of c-Jun terminal kinases
www.researchsquare.com/article/rs-6...
Guanine is an inhibitor of c-Jun terminal kinases
www.researchsquare.com/article/rs-6...
Guanine is an inhibitor of c-Jun terminal kinases
The toxicity of purine bases adenine and guanine is mostly recognized when associated with inborn errors of purine metabolism such as Lesch-Nyhan syndrome, and metabolic diseases with a lifestyle comp...
www.researchsquare.com
June 12, 2025 at 4:29 PM
New exciting preprint from our CfBT and associates!
Guanine is an inhibitor of c-Jun terminal kinases
www.researchsquare.com/article/rs-6...
Guanine is an inhibitor of c-Jun terminal kinases
www.researchsquare.com/article/rs-6...
New exciting preprint from our CfBT and associates!
The 18S rRNA methyltransferase, BUD23, is required for appropriate lipid and mitochondrial metabolism
www.biorxiv.org/content/10.1...
The 18S rRNA methyltransferase, BUD23, is required for appropriate lipid and mitochondrial metabolism
www.biorxiv.org/content/10.1...
www.biorxiv.org
June 12, 2025 at 4:27 PM
New exciting preprint from our CfBT and associates!
The 18S rRNA methyltransferase, BUD23, is required for appropriate lipid and mitochondrial metabolism
www.biorxiv.org/content/10.1...
The 18S rRNA methyltransferase, BUD23, is required for appropriate lipid and mitochondrial metabolism
www.biorxiv.org/content/10.1...
Upcoming: Joanna Chiu's Seminar at the CfBT!
Date: Tuesday, 13 May 2025
Time: 13:00-14:00
Venue: Michael Smith Lecture Theatre
Title: “Metabolic and environmental regulation of circadian biology”.
Date: Tuesday, 13 May 2025
Time: 13:00-14:00
Venue: Michael Smith Lecture Theatre
Title: “Metabolic and environmental regulation of circadian biology”.
May 9, 2025 at 2:03 PM
Upcoming: Joanna Chiu's Seminar at the CfBT!
Date: Tuesday, 13 May 2025
Time: 13:00-14:00
Venue: Michael Smith Lecture Theatre
Title: “Metabolic and environmental regulation of circadian biology”.
Date: Tuesday, 13 May 2025
Time: 13:00-14:00
Venue: Michael Smith Lecture Theatre
Title: “Metabolic and environmental regulation of circadian biology”.
CfBT in the News!
www.bbc.co.uk/news/article...
www.bbc.co.uk/news/article...
Afternoon inhaler puff could improve asthma symptoms - study finds
Researchers in Manchester say coordinating asthma medication to the body clock could bring benefits.
www.bbc.co.uk
April 16, 2025 at 9:10 AM
CfBT in the News!
www.bbc.co.uk/news/article...
www.bbc.co.uk/news/article...
Latest from our CfBT!
The impact of dosage timing for inhaled corticosteroids in asthma: a randomised three-way crossover trial thorax.bmj.com/content/earl...
The impact of dosage timing for inhaled corticosteroids in asthma: a randomised three-way crossover trial thorax.bmj.com/content/earl...
The impact of dosage timing for inhaled corticosteroids in asthma: a randomised three-way crossover trial
Background Asthma demonstrates a robust daily rhythm, with airflow obstruction and airway inflammation peaking overnight. Aligning the timing of drug administration with rhythms in disease (chronother...
thorax.bmj.com
April 16, 2025 at 9:04 AM
Latest from our CfBT!
The impact of dosage timing for inhaled corticosteroids in asthma: a randomised three-way crossover trial thorax.bmj.com/content/earl...
The impact of dosage timing for inhaled corticosteroids in asthma: a randomised three-way crossover trial thorax.bmj.com/content/earl...
Reposted by Manchester Centre for Biological Timing
Our latest study
@science.org #Immunology on perception of #hunger and #immunity.
#BrainBody #Melanocortin #AgRP #POMC neurons. #Brain-liver axis. Permissive action of #stress #hormones.
@ukri.org @fbmh-uom.bsky.social
www.science.org/doi/10.1126/...
@science.org #Immunology on perception of #hunger and #immunity.
#BrainBody #Melanocortin #AgRP #POMC neurons. #Brain-liver axis. Permissive action of #stress #hormones.
@ukri.org @fbmh-uom.bsky.social
www.science.org/doi/10.1126/...
Brain sensing of metabolic state regulates circulating monocytes
Brain-initiated hunger signals control circulating monocyte dynamics.
www.science.org
April 7, 2025 at 2:33 PM
Our latest study
@science.org #Immunology on perception of #hunger and #immunity.
#BrainBody #Melanocortin #AgRP #POMC neurons. #Brain-liver axis. Permissive action of #stress #hormones.
@ukri.org @fbmh-uom.bsky.social
www.science.org/doi/10.1126/...
@science.org #Immunology on perception of #hunger and #immunity.
#BrainBody #Melanocortin #AgRP #POMC neurons. #Brain-liver axis. Permissive action of #stress #hormones.
@ukri.org @fbmh-uom.bsky.social
www.science.org/doi/10.1126/...
3 of us representing the Centre at the EuroAgeNet conference in Liverpool!
March 24, 2025 at 9:55 PM
3 of us representing the Centre at the EuroAgeNet conference in Liverpool!
CfBT's recommended reading:
www.nature.com/articles/s42...
www.nature.com/articles/s42...
The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research - Nature Metabolism
This broad group of authors summarizes the impact of circadian factors on metabolic biology and offers recommendations on how to account for and report biological, environmental and experimental facto...
www.nature.com
March 21, 2025 at 8:24 AM
CfBT's recommended reading:
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Don't miss the Spring Clock Club in Coventry on March 20-21!
www.bioclocks.uk/event-detail...
www.bioclocks.uk/event-detail...
Spring Clock Club 2025 Coventry | Bioclocks Uk
Join us for our bi-annual Clock Club gathering!
The main event and talks will be taking place on Friday the 21st of March.
We also have several enriching workshops running on Thursday the 20th of Mar...
www.bioclocks.uk
March 19, 2025 at 4:12 PM
Don't miss the Spring Clock Club in Coventry on March 20-21!
www.bioclocks.uk/event-detail...
www.bioclocks.uk/event-detail...
Reposted by Manchester Centre for Biological Timing
very excited for Clock Club @bioclocksuk.bsky.social this week, and especially for @williams-steph.bsky.social talk on flowering and winter! ❄️🌼
March 19, 2025 at 2:57 PM
very excited for Clock Club @bioclocksuk.bsky.social this week, and especially for @williams-steph.bsky.social talk on flowering and winter! ❄️🌼