Breast International Group
@bigxresearch.bsky.social
The Breast International Group is the largest global network of academic research groups dedicated to curing breast cancer. 🌎
See our community guidelines: https://shorturl.at/hIYbP
See our community guidelines: https://shorturl.at/hIYbP
📰 New in NEJM: Long-term results from the #SUPREMOtrial (BIG 2-04) show when postmastectomy radiotherapy may be safely avoided in “intermediate-risk” #breastcancer patients. A major step toward more tailored, less toxic treatment. www.nejm.org/doi/full/10....
November 7, 2025 at 1:47 PM
📰 New in NEJM: Long-term results from the #SUPREMOtrial (BIG 2-04) show when postmastectomy radiotherapy may be safely avoided in “intermediate-risk” #breastcancer patients. A major step toward more tailored, less toxic treatment. www.nejm.org/doi/full/10....
At BIG, we support efforts to promote climate awareness and sustainability. 💚 Our Scientific Director, @virginieadam.bsky.social, travelled to #ESMO25 by train 🚊 in an effort to reduce the carbon footprint of congress attendance. #MyESMOstory 🧵
October 22, 2025 at 12:58 PM
At BIG, we support efforts to promote climate awareness and sustainability. 💚 Our Scientific Director, @virginieadam.bsky.social, travelled to #ESMO25 by train 🚊 in an effort to reduce the carbon footprint of congress attendance. #MyESMOstory 🧵
#ESMO25 ! poster 400P reports insights of a co-creation board composed of #breastcancer pts & health care providers on the barriers & actions to be taken to improve #deescalationtrial experience #Optimayoung @tanjaspanic.bsky.social
@AliceFranzoi @unicancer @gustaveroussy.fr @EuropaDonnaEUR
@AliceFranzoi @unicancer @gustaveroussy.fr @EuropaDonnaEUR
October 20, 2025 at 11:05 AM
#ESMO25 ! poster 400P reports insights of a co-creation board composed of #breastcancer pts & health care providers on the barriers & actions to be taken to improve #deescalationtrial experience #Optimayoung @tanjaspanic.bsky.social
@AliceFranzoi @unicancer @gustaveroussy.fr @EuropaDonnaEUR
@AliceFranzoi @unicancer @gustaveroussy.fr @EuropaDonnaEUR
Now at #ESMO25 ! #breastcancer poster session is open, results of an exploratory analysis of the #Lorelei trial exploring the impact of Body Mass Index on efficacy of #taselisib. Go check 349P
@ChiaraDauccia
@elisaagostinetto.bsky.social
@ABCSGVienna
@_SOLTI
@ChiaraDauccia
@elisaagostinetto.bsky.social
@ABCSGVienna
@_SOLTI
October 20, 2025 at 11:04 AM
Now at #ESMO25 ! #breastcancer poster session is open, results of an exploratory analysis of the #Lorelei trial exploring the impact of Body Mass Index on efficacy of #taselisib. Go check 349P
@ChiaraDauccia
@elisaagostinetto.bsky.social
@ABCSGVienna
@_SOLTI
@ChiaraDauccia
@elisaagostinetto.bsky.social
@ABCSGVienna
@_SOLTI
#ESMO25 -PIK3CA helical mutations&enrichment of Macrophages2 predict response to #taselisib in #Lorelei pts. An increased response seen for pts w/ #Lobular #breastcancer treated w/ taselisib regardless of #PIK3CA status @ColletLaetitia @ABCSGVienna @SOLTI @oncoalert.bsky.social @oncodaily
October 18, 2025 at 8:01 AM
#ESMO25 -PIK3CA helical mutations&enrichment of Macrophages2 predict response to #taselisib in #Lorelei pts. An increased response seen for pts w/ #Lobular #breastcancer treated w/ taselisib regardless of #PIK3CA status @ColletLaetitia @ABCSGVienna @SOLTI @oncoalert.bsky.social @oncodaily
Today at #ESMO25 ! @ColletLaetitia3 will give mini-oral presentation on the results of #RNAseq analysis of #Lorelei samples before & after #neoadjuvant treatment of HR+ HER2- BC with #taselisib . 116MO will be in room Cologne Auditorium-CityCube A. #ESMO @ABCSGVienna @_SOLTI
October 18, 2025 at 7:15 AM
Today at #ESMO25 ! @ColletLaetitia3 will give mini-oral presentation on the results of #RNAseq analysis of #Lorelei samples before & after #neoadjuvant treatment of HR+ HER2- BC with #taselisib . 116MO will be in room Cologne Auditorium-CityCube A. #ESMO @ABCSGVienna @_SOLTI
#ESMO25 The latest results from the #POSITIVE study show that temporary interruption of #endocrinetherapy for pregnancy does not add risk of #breastcancer recurrence at 6 yrs median FU. Most pts resumed ET per protocol. @etop_ibcsg @OncoAlert @oncodaily
October 17, 2025 at 1:03 PM
#ESMO25 The latest results from the #POSITIVE study show that temporary interruption of #endocrinetherapy for pregnancy does not add risk of #breastcancer recurrence at 6 yrs median FU. Most pts resumed ET per protocol. @etop_ibcsg @OncoAlert @oncodaily
Proffered paper presentation by Paul Cottu of the #RIBOLARIS trial at #ESMO25 showed that a subset of pts with HR+/HER2− eBC achieved ROR-low disease after neoadjuvant #ribociclib + #endocrinetherapy suggesting they could potentially avoid chemotherapy @_SOLTI @unicancer @OncoAlert
October 17, 2025 at 12:30 PM
Proffered paper presentation by Paul Cottu of the #RIBOLARIS trial at #ESMO25 showed that a subset of pts with HR+/HER2− eBC achieved ROR-low disease after neoadjuvant #ribociclib + #endocrinetherapy suggesting they could potentially avoid chemotherapy @_SOLTI @unicancer @OncoAlert
Reposted by Breast International Group
At the BIG Scientific Meeting @bigxresearch.bsky.social this morning, our Clinical Lead Prof @seamusoreilly.bsky.social presented to international colleagues in two sessions.
We also heard updates on EXPERT and Path for Young.
#BreastCancer
#ESMO25
We also heard updates on EXPERT and Path for Young.
#BreastCancer
#ESMO25
October 17, 2025 at 11:48 AM
At the BIG Scientific Meeting @bigxresearch.bsky.social this morning, our Clinical Lead Prof @seamusoreilly.bsky.social presented to international colleagues in two sessions.
We also heard updates on EXPERT and Path for Young.
#BreastCancer
#ESMO25
We also heard updates on EXPERT and Path for Young.
#BreastCancer
#ESMO25
The BIG Scientific team has arrived in Berlin to attend #ESMO25. Congratulations #ESMO on the 50th anniversary! BIG has contributed to many #breastcancer presentations over the years. Excited for the#POSITIVE, #RIBOLARIS, #LORELEI results, & others this year!#myESMOStory
October 17, 2025 at 12:05 PM
The BIG Scientific team has arrived in Berlin to attend #ESMO25. Congratulations #ESMO on the 50th anniversary! BIG has contributed to many #breastcancer presentations over the years. Excited for the#POSITIVE, #RIBOLARIS, #LORELEI results, & others this year!#myESMOStory
Today at #ESMO25, Dr. Fedro A Peccatori will present the updated results of #POSITIVEtrial after 5 years FU of pts w/ HR+ who have temporarily interrupted #endocrinetherapy to attempt #pregnancy. @etop_ibcsg
October 17, 2025 at 12:03 PM
Today at #ESMO25, Dr. Fedro A Peccatori will present the updated results of #POSITIVEtrial after 5 years FU of pts w/ HR+ who have temporarily interrupted #endocrinetherapy to attempt #pregnancy. @etop_ibcsg
Reposted by Breast International Group
Our Assistant Operations Director, Dr @lisa-fox.bsky.social, is presenting the Greener Trials project at next week's @bigxresearch.bsky.social Pink October Webinar 2025.
Find out more and register to attend here:
bigagainstbreastcancer.org/events/big-p...
#BreastCancer #GreenSky
Find out more and register to attend here:
bigagainstbreastcancer.org/events/big-p...
#BreastCancer #GreenSky
BIG Pink October Webinar 2025
BIG Pink October Webinar 2025 - Breast International Group
bigagainstbreastcancer.org
October 17, 2025 at 10:51 AM
Our Assistant Operations Director, Dr @lisa-fox.bsky.social, is presenting the Greener Trials project at next week's @bigxresearch.bsky.social Pink October Webinar 2025.
Find out more and register to attend here:
bigagainstbreastcancer.org/events/big-p...
#BreastCancer #GreenSky
Find out more and register to attend here:
bigagainstbreastcancer.org/events/big-p...
#BreastCancer #GreenSky
Wonderful to meet with our colleagues from @LACOG_group and #GAICO at the 2025 BIG Scientific Meeting in Berlin. Together, we’re strengthening international collaboration to advance breast cancer research and improve outcomes for patients worldwide 🌎💗
October 17, 2025 at 11:02 AM
Wonderful to meet with our colleagues from @LACOG_group and #GAICO at the 2025 BIG Scientific Meeting in Berlin. Together, we’re strengthening international collaboration to advance breast cancer research and improve outcomes for patients worldwide 🌎💗
Great to connect with members of BIG’s Patient Partnership Initiative during the 2025 BIG Scientific Meeting. @tanjaspanic.bsky.social , @evaschumacherwulf.bsky.social @christeeny513.bsky.social. Together, we’re working to ensure that patients’ voices help shape breast cancer research. 💗
October 17, 2025 at 10:37 AM
Great to connect with members of BIG’s Patient Partnership Initiative during the 2025 BIG Scientific Meeting. @tanjaspanic.bsky.social , @evaschumacherwulf.bsky.social @christeeny513.bsky.social. Together, we’re working to ensure that patients’ voices help shape breast cancer research. 💗
Thank you @DrSoumenDasSurg and our colleague from India Dr. Tanmoy Kumar Mandal, who attended the BIG Scientific Meeting. Happy to see you all in person 🎀 😊
October 17, 2025 at 10:17 AM
Thank you @DrSoumenDasSurg and our colleague from India Dr. Tanmoy Kumar Mandal, who attended the BIG Scientific Meeting. Happy to see you all in person 🎀 😊
Our BIG Executive Board member Dr. Ines Vaz Luis decentralized Clinical Trials and shared the example of @WeShare_Onco platform to the BIG groups at the BIG Scientific Meeting. @unicancer @GustaveRoussy
October 17, 2025 at 8:54 AM
Our BIG Executive Board member Dr. Ines Vaz Luis decentralized Clinical Trials and shared the example of @WeShare_Onco platform to the BIG groups at the BIG Scientific Meeting. @unicancer @GustaveRoussy
In the light of the emerging technologies in oncology, a talk was given by Dr. J. Kather, who presented at the BIG Scientific Meeting a keynote speech on #ArtificialIntelligence in #precisiononcology.
October 17, 2025 at 8:33 AM
In the light of the emerging technologies in oncology, a talk was given by Dr. J. Kather, who presented at the BIG Scientific Meeting a keynote speech on #ArtificialIntelligence in #precisiononcology.
#BIGgroups representatives are meeting this morning in Berlin at the second 2025 BIG Scientific Meeting this year, a great opportunity to provide an update on the ongoing BIG studies and projects and discuss new proposals. #breastcancer
October 17, 2025 at 8:06 AM
#BIGgroups representatives are meeting this morning in Berlin at the second 2025 BIG Scientific Meeting this year, a great opportunity to provide an update on the ongoing BIG studies and projects and discuss new proposals. #breastcancer
BIG is proud to be part of Europa Donna Breast Health Day 2025 led by @EuropaDonnaEUR. Patient advocates and policymakers @Europarl_EN met to promote prevention, early detection, health equity. Orsolya Birta & @Carmela_surgery reinforced BIG’s commitment to research & patients.
October 15, 2025 at 2:33 PM
BIG is proud to be part of Europa Donna Breast Health Day 2025 led by @EuropaDonnaEUR. Patient advocates and policymakers @Europarl_EN met to promote prevention, early detection, health equity. Orsolya Birta & @Carmela_surgery reinforced BIG’s commitment to research & patients.
Yesterday at #BePrecise2025, @aftimosp highlighted #AURORA, an academic study led by @BIGxResearch & mainly supported by @BCRFCure. It identifies genetic changes in mBC—showcasing how molecular profiling drives #precisiononcology to guide treatment & improve outcomes
@be__precise
@be__precise
September 26, 2025 at 10:14 AM
Yesterday at #BePrecise2025, @aftimosp highlighted #AURORA, an academic study led by @BIGxResearch & mainly supported by @BCRFCure. It identifies genetic changes in mBC—showcasing how molecular profiling drives #precisiononcology to guide treatment & improve outcomes
@be__precise
@be__precise
Today, BIG’s team, Virginie Adam & Thayane Crestani, are at #BePrecise2025, where collaboration between clinicians & researchers highlights how #precisiononcology can enhance patient care: Cancer profiling, Targeted therapies, Multi-omics, AI & molecular imaging. @be__precise
September 25, 2025 at 3:03 PM
Today, BIG’s team, Virginie Adam & Thayane Crestani, are at #BePrecise2025, where collaboration between clinicians & researchers highlights how #precisiononcology can enhance patient care: Cancer profiling, Targeted therapies, Multi-omics, AI & molecular imaging. @be__precise
🎉 The EXPERT trial has reached its recruitment target! Thanks to all the participants. This trial will be able to confirm if the Prosigna (PAM50) assay can identify women who may safely omit radiation therapy after breast cancer surgery. @BCTrialsANZ
August 28, 2025 at 8:51 AM
🎉 The EXPERT trial has reached its recruitment target! Thanks to all the participants. This trial will be able to confirm if the Prosigna (PAM50) assay can identify women who may safely omit radiation therapy after breast cancer surgery. @BCTrialsANZ
New pub 📢 The #POSITIVEtrial manuscript led by @IDemeestere has been published in The Breast! It explores hormonal factors predictive of fertility in young women with #breastcancer interrupting #endocrinetherapy to try for pregnancy. @etop_ibcsg
🔗 www.thebreastonline.com/article/S096...
🔗 www.thebreastonline.com/article/S096...
August 19, 2025 at 10:30 AM
New pub 📢 The #POSITIVEtrial manuscript led by @IDemeestere has been published in The Breast! It explores hormonal factors predictive of fertility in young women with #breastcancer interrupting #endocrinetherapy to try for pregnancy. @etop_ibcsg
🔗 www.thebreastonline.com/article/S096...
🔗 www.thebreastonline.com/article/S096...