New article: "Chromosome identification methods"

If we have a chromosome, how do we know what number it is? There are lots of ways scientists do this, but AFAIK, none of them are well-refined, non-destructive, and confidently informative.

Professor George Church, renowned Harvard geneticist and biotechnologist, spoke at Reproductive Frontiers 2025. What does the future hold for xenotransplantation, ectogenesis, de-extinction, and gene editing? + Great Q&A.

Watch: www.youtube.com/watch?v=cxWO...

Thanks to
@geochurch.bsky.social !

Max Berry, biologist and founder of Nucleostream, spoke at Reproductive Frontiers 2025. Germline gene editing: How does it work? What is it good for? What's next for this field?

Watch here: www.youtube.com/watch?v=6-R3...

Professor Steve Hsu, found of Genomic Prediction, spoke at Reproductive Frontiers 2025. What do & don't we know about the genetics of traits? How can this be used to empower parents on behalf of their future children through embryo selection?

Watch here:
www.youtube.com/watch?v=n64r...

New essay: "Genomic emancipation"

What's the vision motivating reprogenetic technology? My simple answer is genomic emancipation:

Empowering parents to make genomic choices on behalf of their future children.

I'll read out the main part of the essay on Sunday, +Q&A.
Links⬇️

A few projects you might find interesting and that might help a bit to build the reprogenetics field:
* Submit deregulation suggestions
* Iterated selection scheduling simulations
* Can genomic vectoring have large effects?
* Power of recombinant chromosome selection
1/2

How could the US support frontier reproductive technology? Six recommendations:

* Waive CITES treaty restrictions on importing cell lines
* Remove the Section 749 appropriations rider banning genetic modification
* Repeal the Dickey-Wicker rider

From a technical standpoint, how do we get to strong human germline engineering? Since this field is full of unsolved problems and open questions, the answer is uncertain and complicated. We've just published a visual roadmap, as a zoomed-out guide.
berkeleygenomics.org/articles/Vis...

New article by Morpheus: "What Uniparental Disomy Tells Us About Improper Imprinting in Humans"

The epigenomic correctness problem is the main barrier to human germline engineering. How can we tell when a cell is epigenomically competent to make a healthy baby?

Short article: "The vision of Bill Thurston"

One of the conflicts around human germline genomic engineering is: Who decides what "good" genes are? The answer is "parents decide for their future children".

New article: "The principle of genomic liberty"

How should we structure society so that we can get the benefits of human germline genomic engineering, without infringing on anyone's human rights?🧵

www.lesswrong.com/posts/rxcGvP...