BASE mRNA Facility
basemrna.bsky.social
BASE mRNA Facility
@basemrna.bsky.social
A federally-funded RNA Manufacture and Research Hub located at AIBN, University of Queensland. | Posts about the all latest mRNA news | Reposts are not endorsements.

W: basefacility.org.au
E: base@uq.edu.au
🔬 Ever wondered what mRNA-LNPs look like?

Thanks to the Wolfram Group, we have this stunning image of BASE-produced eGFP mRNA encapsulated in LNPs!

We’re proud to support researchers with high-quality #mRNA and #LNP, helping drive innovation from the lab to real-world applications.
February 26, 2025 at 4:02 AM
We are looking for a Software Engineer who will lead the development of software platform for the design of #mRNA medicines. The role will include developing, implementing, and maintaining mRNA design software to industry standards.
www.linkedin.com/jobs/view/41...
The University of Queensland hiring Software Developer – mRNA design in St Lucia, Queensland, Australia | LinkedIn
Posted 1:56:31 PM. BASE Facility at Australian Institute for Bioengineering and Nanotechnology (AIBN)Full-time (100%),…See this and similar jobs on LinkedIn.
www.linkedin.com
February 11, 2025 at 2:51 AM
We look forward to working with the Vaxxas team to deliver #mRNA vaccines using the microarray patch!
January 15, 2025 at 11:40 PM
Reposted by BASE mRNA Facility
#mRNA meets cell therapies! It was great to collaborate with Fernando Guimaraes's team to develop mRNA CARs and delivered them to NK cells. NKs transfected with EphA2 CAR mRNA elicited a strong anti-tumour response in animal sarcoma models.

onlinelibrary.wiley.com/doi/10.1002/...
Enhancement of anti‐sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2‐targeted CAR
Human NK cells can be efficiently transfected with mRNA to safely express an EphA2-CAR without genomic alterations. EphA2-targeted CAR-NK cells exhibit enhanced cytotoxicity against paediatric sarco...
onlinelibrary.wiley.com
January 13, 2025 at 3:22 PM
We’re excited to announce that we’re back in action and ready to help you achieve your #mRNA goals in 2025. Our team is re-energised and eager to continue providing the reliable, high-quality mRNA solutions.

Reach out to us to discuss your project need! 🧬
✉️ base@uq.edu.au
January 9, 2025 at 12:57 AM
Reposted by BASE mRNA Facility
Earlier this year I had the opportunity to present a TEDx talk on the transformative potential of personalised #mRNA vaccines for cancer. The recording is out now:

www.youtube.com/watch?v=BnSO...

#RNAsky #RNAtx @basemrna.bsky.social
How personalized mRNA vaccines could revolutionize cancer treatment | Seth Cheetham | TEDxUQ
YouTube video by TEDx Talks
www.youtube.com
December 9, 2024 at 10:55 PM
BASE team took some time to celebrate the progress we’ve achieved this year. 🎄 From a delicious team lunch to an epic round of laser tag! 💥🔫 it was a fantastic way to bond, recharge, and have fun.

A huge shoutout to our amazing team—your hard work and dedication make all the difference.
December 5, 2024 at 11:09 PM
Reposted by BASE mRNA Facility
There are more ways to design an mRNA than atoms in the universe, so how do you choose the best one? Our new @basemrna.bsky.social software, mRNArchitect enables you to tune expression, stability, reactogenicity and synthesisability to design more potent #mRNA drugs.

www.biorxiv.org/content/10.1...
mRNArchitect: optimized design of mRNA sequences
Summary: mRNA design is the critical first step in the development of a new vaccine or therapy. The mRNA primary sequence is assembled from multiple elements, including the coding sequence of the targ...
www.biorxiv.org
December 4, 2024 at 10:19 PM
We are excited to introduce #mRNArchitect - a software toolkit for designing and optimising mRNA sequences.

basefacility.org.au/software/

This freely available software enables users to generate mRNA candidates optimised for expression, stability& immunogenicity.
Software - BASE mRNA facility
mRNA design software - mRNArchitect is a software toolkit to design, build and optimise mRNA vaccines and therapies.
basefacility.org.au
December 5, 2024 at 12:22 AM
Reposted by BASE mRNA Facility
I made a starter pack for interesting people in the mRNA vaccines and therapeutics space. Message me if you want to be added. #RNAsky

go.bsky.app/VSHfBce
November 25, 2024 at 5:57 AM
We are #hiring!

We're looking for an mRNA Production Scientist, a Software Developer, and a Bioinformatician.

Join our mRNA Production and mRNA Design teams as we push the boundaries of mRNA innovation! 🧬
www.linkedin.com/posts/base-f...
November 25, 2024 at 6:11 AM
Reposted by BASE mRNA Facility
We're building Australia's first centre for the designing and manufacturing personalised cancer vaccines at the BASE mRNA facility. On the PhaseIII podcast I discuss the transformative potential of mRNA for cancer and our efforts to bring this tech to patients.

podcasts.apple.com/au/podcast/v...
VAXXED: Game on, with BASE and WEHI
Podcast Episode · Phase III · 19/11/2024 · 26m
podcasts.apple.com
November 19, 2024 at 11:25 PM