Arin Bhattacharjee
@arbhatta.bsky.social
Neuroscientist, pharmacologist, professor, drug maker.
Pinned
Arin Bhattacharjee
@arbhatta.bsky.social
· Nov 23
Opioid-Free Pain Relief with Arin Bhattacharjee - Driven to Discover
Effective, long-lasting, non-addictive pain relief—it sounds too good to be true. But thanks to the imagination (and perseverance) of University at Buffalo neuroscientist/pharmacologist Arin Bhattacha...
www.buzzsprout.com
Reposted by Arin Bhattacharjee
Moving beyond traditional pore blockers! New research found that locally targeting the scaffolding of NaV1.8 channels with a lipidated peptidomimetic reduced chronic neuropathic pain behaviors for a prolonged duration after a single injection journals.lww.com/pain/fulltex...
Pharmacologically enabling the degradation of NaV1.8... : PAIN
le, yet local anesthetics are neither specific nor long-lasting. In lieu of a pore blocker approach, we show a pharmacological method targeting the scaffolding and degradation of NaV1.8 channels, whic...
journals.lww.com
May 29, 2025 at 12:59 PM
Moving beyond traditional pore blockers! New research found that locally targeting the scaffolding of NaV1.8 channels with a lipidated peptidomimetic reduced chronic neuropathic pain behaviors for a prolonged duration after a single injection journals.lww.com/pain/fulltex...
Reposted by Arin Bhattacharjee
On changes to #NIH indirect rates, there is a law in place that prohibits NIH from making such changes without the approval of Congress. See Division D, Title II Section 224 of The Further Consolidated Appropriations Act, 2024 (Public Law No: 118-47) grants.nih.gov/grants/guide...
NOT-OD-24-110: Notice of Legislative Mandates in Effect for FY 2024
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Legislative Mandates in Effect for FY 2024 NOT-OD-24-110. NIH
grants.nih.gov
February 8, 2025 at 12:56 AM
On changes to #NIH indirect rates, there is a law in place that prohibits NIH from making such changes without the approval of Congress. See Division D, Title II Section 224 of The Further Consolidated Appropriations Act, 2024 (Public Law No: 118-47) grants.nih.gov/grants/guide...
Reposted by Arin Bhattacharjee
From what I hear from multiple people in the space, the latest NIH indirect costs for medical research grants will basically mean the end most academic medical centers.
February 8, 2025 at 1:36 AM
From what I hear from multiple people in the space, the latest NIH indirect costs for medical research grants will basically mean the end most academic medical centers.
Reposted by Arin Bhattacharjee
EMERGENCY PIECE: Elon Musk Wants to Get Operational Control of the Treasury’s Payment System. This Could Not Possibly Be More Dangerous. Worse, exclusive new information revealed here explicate how Musk’s actions relate to Treasury Secretary Scott Bessent
(Link at the end)
(Link at the end)
February 3, 2025 at 11:10 AM
EMERGENCY PIECE: Elon Musk Wants to Get Operational Control of the Treasury’s Payment System. This Could Not Possibly Be More Dangerous. Worse, exclusive new information revealed here explicate how Musk’s actions relate to Treasury Secretary Scott Bessent
(Link at the end)
(Link at the end)
Work from my student Raider Rodriguez who showed that the PY(A) Peptide provides weeks of pain relief and maintenance of subchondral bone in arthritic preclinical pain model.
A small lipidated peptide targeting NaV1.8 channels attenuates osteoarthritic pain behavior and prevents bone erosion https://www.biorxiv.org/content/10.1101/2025.01.28.635324v1
February 2, 2025 at 5:00 PM
Work from my student Raider Rodriguez who showed that the PY(A) Peptide provides weeks of pain relief and maintenance of subchondral bone in arthritic preclinical pain model.
January 15, 2025 at 2:33 AM