Anurag Adhikari, PhD
@anuragadhikari.bsky.social
Innate-B cell scientist diving into T cells with an epidemiological edge, for Virus/Bacteria alike. Vocal on Community, Privilege, and Opportunities.
@La Trobe Institute for Molecular Sciences 🇦🇺 and @Kathmandu Research Institute for Biological Science 🇳🇵
@La Trobe Institute for Molecular Sciences 🇦🇺 and @Kathmandu Research Institute for Biological Science 🇳🇵
Reposted by Anurag Adhikari, PhD
June 10, 2025 at 7:14 PM
Reposted by Anurag Adhikari, PhD
Characterizing Long COVID Symptoms During Early Childhood.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
June 11, 2025 at 1:36 AM
Characterizing Long COVID Symptoms During Early Childhood.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Reposted by Anurag Adhikari, PhD
Thank you to our reviewers: @Anna.Durbin @sbiering.bsky.social @vasiliya-kril.bsky.social @Eng.Eong.Ooi @anuragadhikari.bsky.social @Sujan.Shresta @Pradhan.Aunji
Preprint author(s): @Bobby.Brooke.Herrera
Preprint author(s): @Bobby.Brooke.Herrera
May 28, 2025 at 7:11 PM
Thank you to our reviewers: @Anna.Durbin @sbiering.bsky.social @vasiliya-kril.bsky.social @Eng.Eong.Ooi @anuragadhikari.bsky.social @Sujan.Shresta @Pradhan.Aunji
Preprint author(s): @Bobby.Brooke.Herrera
Preprint author(s): @Bobby.Brooke.Herrera
Reposted by Anurag Adhikari, PhD
🔊🚨‼️Check out our reviews on whether immunity to yellow fever can be protective towards Dengue virus too!
rrid.mitpress.mit.edu/pub/ipcox645...
rrid.mitpress.mit.edu/pub/ipcox645...
Reviews of
Reviewer(s): A Durbin (Johns Hopkins University) | 📒📒📒 ◻️◻️ • S Biering & V Kril (UC San Diego) | 📒📒📒◻️◻️ • E E Ooi (Duke-NUS Medical School) | 📘📘📘📘📘 • A Adhikari & S Shresta & P Aunji (La Jolla...
rrid.mitpress.mit.edu
May 28, 2025 at 7:06 PM
🔊🚨‼️Check out our reviews on whether immunity to yellow fever can be protective towards Dengue virus too!
rrid.mitpress.mit.edu/pub/ipcox645...
rrid.mitpress.mit.edu/pub/ipcox645...
Reposted by Anurag Adhikari, PhD
As a first #ImmunoSky post, I’m excited to share our latest pre-print, by the fantastic Mitchell Zheng!
www.biorxiv.org/content/10.1...
Our group is interested in virus-specific CD4 T cells, which means we often use in vitro stimulations (like the AIM assay) to find our cells of interest. 🧵 1/9
www.biorxiv.org/content/10.1...
Our group is interested in virus-specific CD4 T cells, which means we often use in vitro stimulations (like the AIM assay) to find our cells of interest. 🧵 1/9
www.biorxiv.org
December 20, 2024 at 3:39 AM
As a first #ImmunoSky post, I’m excited to share our latest pre-print, by the fantastic Mitchell Zheng!
www.biorxiv.org/content/10.1...
Our group is interested in virus-specific CD4 T cells, which means we often use in vitro stimulations (like the AIM assay) to find our cells of interest. 🧵 1/9
www.biorxiv.org/content/10.1...
Our group is interested in virus-specific CD4 T cells, which means we often use in vitro stimulations (like the AIM assay) to find our cells of interest. 🧵 1/9
Reposted by Anurag Adhikari, PhD
I’ve tried to put together a starter pack of immunologists/scientists exploring B Cell Repertoires and Antibody Affinities.
Please feel free to share/join!
go.bsky.app/4P64DmM
Please feel free to share/join!
go.bsky.app/4P64DmM
December 3, 2024 at 11:09 PM
I’ve tried to put together a starter pack of immunologists/scientists exploring B Cell Repertoires and Antibody Affinities.
Please feel free to share/join!
go.bsky.app/4P64DmM
Please feel free to share/join!
go.bsky.app/4P64DmM
Reposted by Anurag Adhikari, PhD
Ask anyone from a Global South country, and they will immediately point out the most visa-hostile countries: USA, UK, Canada, EU (Schengen), and Australia would top the list
communities.springernature.com/posts/visa-f...
communities.springernature.com/posts/visa-f...
Visa-friendly venues for global health meetings
Conference organizers have an obligation to host meetings in locations that are not visa-hostile. Are there ‘visa-friendly’ options that conference organizers should be considering? This crowd-sourced...
communities.springernature.com
December 24, 2024 at 8:20 PM
Ask anyone from a Global South country, and they will immediately point out the most visa-hostile countries: USA, UK, Canada, EU (Schengen), and Australia would top the list
communities.springernature.com/posts/visa-f...
communities.springernature.com/posts/visa-f...
Reposted by Anurag Adhikari, PhD
Coupling antigens from multiple subtypes of influenza can broaden antibody and T cell responses
A monozygotic twins and vaccinated newborns study with an old twist: antigen conjugation to full T cells in providing broad B cell help!
www.science.org/doi/...
1/10
A monozygotic twins and vaccinated newborns study with an old twist: antigen conjugation to full T cells in providing broad B cell help!
www.science.org/doi/...
1/10
December 24, 2024 at 12:20 AM
Coupling antigens from multiple subtypes of influenza can broaden antibody and T cell responses
A monozygotic twins and vaccinated newborns study with an old twist: antigen conjugation to full T cells in providing broad B cell help!
www.science.org/doi/...
1/10
A monozygotic twins and vaccinated newborns study with an old twist: antigen conjugation to full T cells in providing broad B cell help!
www.science.org/doi/...
1/10
Reposted by Anurag Adhikari, PhD
Finally got on Bluesky to share some work I'm really proud of...
Using a tiled amplicon approach, we were able to sequence TB directly from sputum, without culture. This could help make WGS of TB (which can take weeks to culture) much faster at a similar price point to widespread SC2 sequencing.
Using a tiled amplicon approach, we were able to sequence TB directly from sputum, without culture. This could help make WGS of TB (which can take weeks to culture) much faster at a similar price point to widespread SC2 sequencing.
Sharing our work expanding SARS-CoV-2 style tiled amplicon sequencing for whole bacteria genomes directly from clinical samples, showing examples with M.tb (>4 mb) and Strep pneumo (>2 mb).
Led by Chaney Kalinich, Freddy Gonzalez, & Seth Redmond
www.biorxiv.org/content/10.1...
Led by Chaney Kalinich, Freddy Gonzalez, & Seth Redmond
www.biorxiv.org/content/10.1...
December 21, 2024 at 12:50 AM
Finally got on Bluesky to share some work I'm really proud of...
Using a tiled amplicon approach, we were able to sequence TB directly from sputum, without culture. This could help make WGS of TB (which can take weeks to culture) much faster at a similar price point to widespread SC2 sequencing.
Using a tiled amplicon approach, we were able to sequence TB directly from sputum, without culture. This could help make WGS of TB (which can take weeks to culture) much faster at a similar price point to widespread SC2 sequencing.
Reposted by Anurag Adhikari, PhD
Health of the world should never be reliant on any one country
Global South governments must invest more in health and become less reliant on aid
www.nytimes.com/2024/12/19/h...
Global South governments must invest more in health and become less reliant on aid
www.nytimes.com/2024/12/19/h...
Trump’s Return May Worsen Financial Woes for Global Health Institutions
The U.S. provides nearly half of the aid for global health, including childhood vaccination, H.I.V. treatment and disease surveillance.
www.nytimes.com
December 19, 2024 at 10:28 PM
Health of the world should never be reliant on any one country
Global South governments must invest more in health and become less reliant on aid
www.nytimes.com/2024/12/19/h...
Global South governments must invest more in health and become less reliant on aid
www.nytimes.com/2024/12/19/h...
Reposted by Anurag Adhikari, PhD
💥 My 2024 Mile Marker: The inside scoop on how America lost control of the Bird Flu, opening the door for another pandemic.
"We're in a terrible situation" said @angierasmussen.bsky.social
🧵Here's how we got here & how to get out @kffhealthnews.bsky.social kffhealthnews.org/news/article...
"We're in a terrible situation" said @angierasmussen.bsky.social
🧵Here's how we got here & how to get out @kffhealthnews.bsky.social kffhealthnews.org/news/article...
How America Lost Control of the Bird Flu, Setting the Stage for Another Pandemic - KFF Health News
Exclusive reporting reveals how the United States lost track of a virus that could cause the next pandemic. Problems like the sluggish pace of federal action, a deference to industry, and neglect for ...
kffhealthnews.org
December 20, 2024 at 4:12 PM
💥 My 2024 Mile Marker: The inside scoop on how America lost control of the Bird Flu, opening the door for another pandemic.
"We're in a terrible situation" said @angierasmussen.bsky.social
🧵Here's how we got here & how to get out @kffhealthnews.bsky.social kffhealthnews.org/news/article...
"We're in a terrible situation" said @angierasmussen.bsky.social
🧵Here's how we got here & how to get out @kffhealthnews.bsky.social kffhealthnews.org/news/article...
Reposted by Anurag Adhikari, PhD
The mystery illness in the #DRC was revealed to be #Malaria. The world will move on and the epidemics of poverty and inequity to healthcare access will persist. We cannot address the threat of pandemics by ignoring poverty.
Check out my latest #substack on this
open.substack.com/pub/bktitanj...
Check out my latest #substack on this
open.substack.com/pub/bktitanj...
The Mystery Illness That Never Was
Poverty and Healthcare Inequities as Modern Outbreaks
open.substack.com
December 18, 2024 at 7:35 PM
The mystery illness in the #DRC was revealed to be #Malaria. The world will move on and the epidemics of poverty and inequity to healthcare access will persist. We cannot address the threat of pandemics by ignoring poverty.
Check out my latest #substack on this
open.substack.com/pub/bktitanj...
Check out my latest #substack on this
open.substack.com/pub/bktitanj...
Reposted by Anurag Adhikari, PhD
Neglect, it is.
WHO finds that the direct cause of "the mystery disease" in Congo is malaria, exacerbated by malnutrition. Malaria can be *cured* by a few cheap pills, as long as it's caught early. So these are deaths of neglect.
www.reuters.com/world/africa...
WHO finds that the direct cause of "the mystery disease" in Congo is malaria, exacerbated by malnutrition. Malaria can be *cured* by a few cheap pills, as long as it's caught early. So these are deaths of neglect.
www.reuters.com/world/africa...
December 17, 2024 at 4:16 PM
Neglect, it is.
WHO finds that the direct cause of "the mystery disease" in Congo is malaria, exacerbated by malnutrition. Malaria can be *cured* by a few cheap pills, as long as it's caught early. So these are deaths of neglect.
www.reuters.com/world/africa...
WHO finds that the direct cause of "the mystery disease" in Congo is malaria, exacerbated by malnutrition. Malaria can be *cured* by a few cheap pills, as long as it's caught early. So these are deaths of neglect.
www.reuters.com/world/africa...
Reposted by Anurag Adhikari, PhD
Life isn't even-handed: many cellular components are all either left or right handed. But we are now (uncomfortably) close to being able to make flipped "mirror" cells. A group of us consider and highlight the risks and call for collective effort before we get there.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Confronting risks of mirror life
Broad discussion is needed to chart a path forward.
www.science.org
December 13, 2024 at 6:25 AM
Life isn't even-handed: many cellular components are all either left or right handed. But we are now (uncomfortably) close to being able to make flipped "mirror" cells. A group of us consider and highlight the risks and call for collective effort before we get there.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Anurag Adhikari, PhD
Really cool to see more malaria vaccine candidates in advanced stage clinical trials. Ph2b trial of an erythrocyte stage merozoite targeting vaccine. It was safe, immunogenic and showed modest protective efficacy of 40% in infants 5-17 months.
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Safety and efficacy of the blood-stage malaria vaccine RH5.1/Matrix-M in Burkina Faso: interim results of a double-blind, randomised, controlled, phase 2b trial in children
RH5.1/Matrix-M appears safe and highly immunogenic in African children and shows promising efficacy against clinical malaria when given in a delayed third-dose regimen. This trial is ongoing to further monitor efficacy over time.
www.thelancet.com
December 12, 2024 at 1:41 AM
Really cool to see more malaria vaccine candidates in advanced stage clinical trials. Ph2b trial of an erythrocyte stage merozoite targeting vaccine. It was safe, immunogenic and showed modest protective efficacy of 40% in infants 5-17 months.
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Reposted by Anurag Adhikari, PhD
Today, I travelled back in time, to the pre polio vaccine era
I closed my eyes, imagined being paralyzed… unable to breathe
I imagined being stuck in this claustrophobic iron lung, to breathe
Maybe we all need to time travel, to appreciate how science & public health saves us, every day.
I closed my eyes, imagined being paralyzed… unable to breathe
I imagined being stuck in this claustrophobic iron lung, to breathe
Maybe we all need to time travel, to appreciate how science & public health saves us, every day.
December 11, 2024 at 7:55 PM
Today, I travelled back in time, to the pre polio vaccine era
I closed my eyes, imagined being paralyzed… unable to breathe
I imagined being stuck in this claustrophobic iron lung, to breathe
Maybe we all need to time travel, to appreciate how science & public health saves us, every day.
I closed my eyes, imagined being paralyzed… unable to breathe
I imagined being stuck in this claustrophobic iron lung, to breathe
Maybe we all need to time travel, to appreciate how science & public health saves us, every day.
Reposted by Anurag Adhikari, PhD
Are you a senior PhD student or postdoc? Do you have a cool science story to tell? Do you want to visit Buffalo when the weather is perfect? Then apply for the Emerging Leaders Seminar Series at Roswell Park! DM or email me with questions. (RT please!)
www.roswellpark.org/education/pr...
www.roswellpark.org/education/pr...
Emerging Leaders in Cancer Research Seminar Series
The Roswell Park Emerging Leaders in Cancer Research Seminar Series features lectures by outstanding junior scientists from around the country on a diverse range of cancer-focused topics. This include...
www.roswellpark.org
December 11, 2024 at 7:05 PM
Are you a senior PhD student or postdoc? Do you have a cool science story to tell? Do you want to visit Buffalo when the weather is perfect? Then apply for the Emerging Leaders Seminar Series at Roswell Park! DM or email me with questions. (RT please!)
www.roswellpark.org/education/pr...
www.roswellpark.org/education/pr...
Reposted by Anurag Adhikari, PhD
I cannot understand that the US can’t just stop selling of raw milk with all that’s going on with H5N1 + implement strict biosafety on the farms. Do you know the level of protection required when working with the virus in the laboratory? The current situation US is a global health security risk
December 11, 2024 at 7:24 AM
I cannot understand that the US can’t just stop selling of raw milk with all that’s going on with H5N1 + implement strict biosafety on the farms. Do you know the level of protection required when working with the virus in the laboratory? The current situation US is a global health security risk
Reposted by Anurag Adhikari, PhD
The NIH STOMP shows that tecovirimat is safe, but doesn't expedite lesion healing or alleviate pain in persons with clade II mpox - study enrollment has been halted.
PALM 007 in DRC showed the same for clade I in DRC and emphasized the importance of supportive care
www.nih.gov/news-events/...
PALM 007 in DRC showed the same for clade I in DRC and emphasized the importance of supportive care
www.nih.gov/news-events/...
NIH Study Finds Tecovirimat Was Safe but Did Not Improve Mpox Resolution or Pain
Study Examined Tecovirimat in Countries Affected by Global Clade II Mpox Outbreak.
www.nih.gov
December 10, 2024 at 9:00 PM
The NIH STOMP shows that tecovirimat is safe, but doesn't expedite lesion healing or alleviate pain in persons with clade II mpox - study enrollment has been halted.
PALM 007 in DRC showed the same for clade I in DRC and emphasized the importance of supportive care
www.nih.gov/news-events/...
PALM 007 in DRC showed the same for clade I in DRC and emphasized the importance of supportive care
www.nih.gov/news-events/...
Reposted by Anurag Adhikari, PhD
I am looking for 2 postdoctoral researchers to join my lab to work on the role of HIV-1 accessory proteins in the pathogenesis of HIV/AIDS and viral latency.
Please contact me informally or ‘re-sky’ to anyone you think may be interested. Closing Dec 10th
www.jobs.ac.uk/job/DKV639/p...
Please contact me informally or ‘re-sky’ to anyone you think may be interested. Closing Dec 10th
www.jobs.ac.uk/job/DKV639/p...
Postdoctoral Research Associate at King's College London
Discover an exciting academic career path as a Postdoctoral Research Associate at jobs.ac.uk. Don't miss out on this job opportunity - apply today!
www.jobs.ac.uk
November 27, 2024 at 9:56 AM
I am looking for 2 postdoctoral researchers to join my lab to work on the role of HIV-1 accessory proteins in the pathogenesis of HIV/AIDS and viral latency.
Please contact me informally or ‘re-sky’ to anyone you think may be interested. Closing Dec 10th
www.jobs.ac.uk/job/DKV639/p...
Please contact me informally or ‘re-sky’ to anyone you think may be interested. Closing Dec 10th
www.jobs.ac.uk/job/DKV639/p...
Reposted by Anurag Adhikari, PhD
What a distinct pleasure it is to see this very well deserved recognition for such a great colleague and friend - Dr. Placide Mbala-Kingebeni 👏👏👏
www.nature.com/articles/d41...
www.nature.com/articles/d41...
This doctor raised the alarm about a deadly mpox outbreak that went global
Placide Mbala is part of Nature’s 10, a list of people who shaped science in 2024.
www.nature.com
December 9, 2024 at 5:09 PM
What a distinct pleasure it is to see this very well deserved recognition for such a great colleague and friend - Dr. Placide Mbala-Kingebeni 👏👏👏
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Anurag Adhikari, PhD
For those wondering why we seem to be so behind when it comes to effective mucosal vaccines against respiratory viruses, this really excellent overview from leaders in the field offers a great summary:
www.nature.com/articles/s41...
few additional points for those who want a bit more detail🧵:
www.nature.com/articles/s41...
few additional points for those who want a bit more detail🧵:
Challenges for developing broad-based mucosal vaccines for respiratory viruses - Nature Biotechnology
Nature Biotechnology - Challenges for developing broad-based mucosal vaccines for respiratory viruses
www.nature.com
December 7, 2024 at 2:41 PM
For those wondering why we seem to be so behind when it comes to effective mucosal vaccines against respiratory viruses, this really excellent overview from leaders in the field offers a great summary:
www.nature.com/articles/s41...
few additional points for those who want a bit more detail🧵:
www.nature.com/articles/s41...
few additional points for those who want a bit more detail🧵:
Reposted by Anurag Adhikari, PhD
B CELL FUN FACT: Secrets of the GC #2
There are 300 billion B cells with total mass of 60g in the human body. That is 3 times the number of stars in the Milky Way! Naïve B cell express >10 million unique antibodies to protect us from this universe of possible antigens!
www.pnas.org/doi/10.1073/...
There are 300 billion B cells with total mass of 60g in the human body. That is 3 times the number of stars in the Milky Way! Naïve B cell express >10 million unique antibodies to protect us from this universe of possible antigens!
www.pnas.org/doi/10.1073/...
The total mass, number, and distribution of immune cells in the human body | PNAS
The immune system is a complex network of cells with critical functions in health
and disease. However, a comprehensive census of the cells compris...
www.pnas.org
December 9, 2024 at 11:22 AM
B CELL FUN FACT: Secrets of the GC #2
There are 300 billion B cells with total mass of 60g in the human body. That is 3 times the number of stars in the Milky Way! Naïve B cell express >10 million unique antibodies to protect us from this universe of possible antigens!
www.pnas.org/doi/10.1073/...
There are 300 billion B cells with total mass of 60g in the human body. That is 3 times the number of stars in the Milky Way! Naïve B cell express >10 million unique antibodies to protect us from this universe of possible antigens!
www.pnas.org/doi/10.1073/...
Reposted by Anurag Adhikari, PhD
This is a magnificent piece about how the NIH is “confronting health threats in a changing world,” here & worldwide
I fear that the men who Trump wants to lead HHS, which oversees NIH, and NIH will do untold damage; I hope I am wrong
www.thelancet.com/journals/lan...
I fear that the men who Trump wants to lead HHS, which oversees NIH, and NIH will do untold damage; I hope I am wrong
www.thelancet.com/journals/lan...
How the US National Institutes of Health is confronting health threats in a changing world
The overall health and wellbeing of a population serves as a fundamental indicator of whether a society is meeting its people's most important needs. Achieving health for all people is only possible with educational opportunity, economic productivity, effective government, international cooperation, and peace. As the single largest public funder of biomedical, behavioural, and social sciences research worldwide, the US National Institutes of Health (NIH) has a crucial role in promoting healthy societies.
www.thelancet.com
December 6, 2024 at 11:02 PM
This is a magnificent piece about how the NIH is “confronting health threats in a changing world,” here & worldwide
I fear that the men who Trump wants to lead HHS, which oversees NIH, and NIH will do untold damage; I hope I am wrong
www.thelancet.com/journals/lan...
I fear that the men who Trump wants to lead HHS, which oversees NIH, and NIH will do untold damage; I hope I am wrong
www.thelancet.com/journals/lan...
Reposted by Anurag Adhikari, PhD
We are opening a call for applications 2025 – Creation of new junior research groups at the Institut Pasteur in Paris @pasteur.fr all details on our web site : research.pasteur.fr/en/call/call...
Call for applications 2025 – Creation of new research groups at the Institut Pasteur | Research - Institut Pasteur
research.pasteur.fr
December 8, 2024 at 3:04 PM
We are opening a call for applications 2025 – Creation of new junior research groups at the Institut Pasteur in Paris @pasteur.fr all details on our web site : research.pasteur.fr/en/call/call...