AnHoi
@anheu.bsky.social
MD, living in 🇨🇭, team science. Pro Ukraine 🇺🇦🌻💙💛📎Slava Ukraini! Pro democracy, pro feminism.
Reposted by AnHoi
A more appropriate title...
January 27, 2026 at 9:33 PM
A more appropriate title...
Reposted by AnHoi
BREAKING: An Arrest Warrant has just been issued for former Proud Boy Leader and seditionist Enrique Tarrio in Washington DC, for failing to turn his phone over to authorities, like required by law.
Another Crook that Trump pardoned breaking the law again. What a complete piece of crap.
Another Crook that Trump pardoned breaking the law again. What a complete piece of crap.
January 27, 2026 at 8:51 PM
BREAKING: An Arrest Warrant has just been issued for former Proud Boy Leader and seditionist Enrique Tarrio in Washington DC, for failing to turn his phone over to authorities, like required by law.
Another Crook that Trump pardoned breaking the law again. What a complete piece of crap.
Another Crook that Trump pardoned breaking the law again. What a complete piece of crap.
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BREAKING: After Trump's allies took over TikTok this week, any mention of "Epstein" in DMs are not permitted.
Here's proof. Anyone else is free to try it.
Here's proof. Anyone else is free to try it.
January 26, 2026 at 11:34 PM
BREAKING: After Trump's allies took over TikTok this week, any mention of "Epstein" in DMs are not permitted.
Here's proof. Anyone else is free to try it.
Here's proof. Anyone else is free to try it.
Reposted by AnHoi
Interesting 🤔 Makes You Wonder About The Assassination Attempt, The Election, And What Is In The Epstein Files….
January 27, 2026 at 8:37 PM
Interesting 🤔 Makes You Wonder About The Assassination Attempt, The Election, And What Is In The Epstein Files….
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How do you forgive a nation that hated having a black president so much, it's given us a decade of Trump and has essentially regressed us, socially, to the 1960s?
January 26, 2026 at 4:36 PM
How do you forgive a nation that hated having a black president so much, it's given us a decade of Trump and has essentially regressed us, socially, to the 1960s?
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BREAKING: The chief federal judge in Minnesota has just ORDERED the Acting Director of ICE, Todd Lyons, to appear personally in court, UNDER OATH, this Friday and warned that he could be held in CONTEMPT for the agency’s repeated violations of court orders.
“The court’s patience is at an end.”
“The court’s patience is at an end.”
January 27, 2026 at 11:30 AM
BREAKING: The chief federal judge in Minnesota has just ORDERED the Acting Director of ICE, Todd Lyons, to appear personally in court, UNDER OATH, this Friday and warned that he could be held in CONTEMPT for the agency’s repeated violations of court orders.
“The court’s patience is at an end.”
“The court’s patience is at an end.”
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January 27, 2026 at 8:15 PM
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BREAKING: Trump doesn’t support the 2nd Amendment.
Q: Do you agree with the assessment from some of your own officials that Alex Pretti is a domestic terrorist or assassin?
TRUMP: Well, I haven't heard that, but he certainly shouldn't have been carrying a gun. I don't like that he had a gun.
TRUMP: Well, I haven't heard that, but he certainly shouldn't have been carrying a gun. I don't like that he had a gun.
January 27, 2026 at 8:51 PM
BREAKING: Trump doesn’t support the 2nd Amendment.
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Trump and Noem's ICE Gestapo is being sent to Italy as security at the Winter Olympics.
Italy should send them to The Hague.
Italy should send them to The Hague.
Italians furious over deployment of ICE agents to bolster US security at Winter Olympics | CNN
Outrage is growing in Italy over the deployment of Immigration and Customs Enforcement (ICE) agents to assist US security operations at the Winter Olympics next month.
edition.cnn.com
January 27, 2026 at 8:44 PM
Trump and Noem's ICE Gestapo is being sent to Italy as security at the Winter Olympics.
Italy should send them to The Hague.
Italy should send them to The Hague.
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Today our new Blockbuster “Melania“. Have a good flight and enj….oh, my god…..
a man in a suit and tie is sitting on an airplane .
ALT: a man in a suit and tie is sitting on an airplane .
media.tenor.com
January 27, 2026 at 7:35 PM
Today our new Blockbuster “Melania“. Have a good flight and enj….oh, my god…..
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People on airplanes would walk out.
January 27, 2026 at 6:35 PM
People on airplanes would walk out.
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It they showed the Melania movie on an airplane in flight, the audience would still walk out.
January 27, 2026 at 1:31 PM
It they showed the Melania movie on an airplane in flight, the audience would still walk out.
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I’d rather stick a red hot poker in my eyes than watch MELANIA, the Movie.
How about you?
How about you?
January 27, 2026 at 1:25 PM
I’d rather stick a red hot poker in my eyes than watch MELANIA, the Movie.
How about you?
How about you?
Reposted by AnHoi
pmc.ncbi.nlm.nih.gov/articles/PMC...
"Our findings suggest that EBA may represent an effective therapeutic for the simultaneous targeting of JAK2/STAT3 and MEK/ERK for the treatment of molecularly heterogeneous TNBC with divergent profiles."
"Our findings suggest that EBA may represent an effective therapeutic for the simultaneous targeting of JAK2/STAT3 and MEK/ERK for the treatment of molecularly heterogeneous TNBC with divergent profiles."
Ebastine impairs metastatic spread in triple-negative breast cancer by targeting focal adhesion kinase
We sought to investigate the utility of ebastine (EBA), a second-generation antihistamine with potent anti-metastatic properties, in the context of breast cancer stem cell (BCSC)-suppression in triple...
pmc.ncbi.nlm.nih.gov
January 24, 2025 at 4:50 AM
pmc.ncbi.nlm.nih.gov/articles/PMC...
"Our findings suggest that EBA may represent an effective therapeutic for the simultaneous targeting of JAK2/STAT3 and MEK/ERK for the treatment of molecularly heterogeneous TNBC with divergent profiles."
"Our findings suggest that EBA may represent an effective therapeutic for the simultaneous targeting of JAK2/STAT3 and MEK/ERK for the treatment of molecularly heterogeneous TNBC with divergent profiles."
Reposted by AnHoi
cells exchanged survival signals that kept them alert and active. Dense cancer filled with such neighborhoods was more likely to be sensitive to therapy. In patients with melanoma, lung, and kidney cancers, in whose tumor samples the researchers found higher levels of these energy-efficient, stem
December 9, 2025 at 5:09 PM
cells exchanged survival signals that kept them alert and active. Dense cancer filled with such neighborhoods was more likely to be sensitive to therapy. In patients with melanoma, lung, and kidney cancers, in whose tumor samples the researchers found higher levels of these energy-efficient, stem
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agents that activated mitochondrial function, tumors in mice completely regressed. The study also found that successful immune responses are dependent on teamwork. Activated T-cells clustered next to antigen-presenting cells like dendritic cells in little "immune neighborhoods." Within the pockets,
December 9, 2025 at 5:07 PM
agents that activated mitochondrial function, tumors in mice completely regressed. The study also found that successful immune responses are dependent on teamwork. Activated T-cells clustered next to antigen-presenting cells like dendritic cells in little "immune neighborhoods." Within the pockets,
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that checkpoint inhibitor drugs such as anti-PD-1 therapy -already used in hospitals- work best when they expand these stem-like and metabolically fit T-cells. In contrast, people whose immune reactions were regulated by exhausted cells fared badly. When checkpoint therapy was administered with
December 9, 2025 at 5:07 PM
that checkpoint inhibitor drugs such as anti-PD-1 therapy -already used in hospitals- work best when they expand these stem-like and metabolically fit T-cells. In contrast, people whose immune reactions were regulated by exhausted cells fared badly. When checkpoint therapy was administered with
Reposted by AnHoi
“stem-like" T-cells. These cells, characterized by genes TCF1 and LEF1, could self-renew and differentiate into new waves of fighters. If these cells were removed from mouse models, immune attacks collapsed; if they were grown, tumors disappeared and survival increased. Researchers also discovered
December 9, 2025 at 5:06 PM
“stem-like" T-cells. These cells, characterized by genes TCF1 and LEF1, could self-renew and differentiate into new waves of fighters. If these cells were removed from mouse models, immune attacks collapsed; if they were grown, tumors disappeared and survival increased. Researchers also discovered
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chemical messenger that recruits other immune defenses. The studies showed that metabolic flexibility, not target recognition, foretells how long the immune cells will keep fighting. Among the populations of tumor-infiltrating T-cells that were so diverse, one stood out as extraordinary: a subset of
December 9, 2025 at 5:06 PM
chemical messenger that recruits other immune defenses. The studies showed that metabolic flexibility, not target recognition, foretells how long the immune cells will keep fighting. Among the populations of tumor-infiltrating T-cells that were so diverse, one stood out as extraordinary: a subset of
Reposted by AnHoi
glycolysis, they switched to oxidative phosphorylation and fatty acid metabolism- an energy strategy that enables them to endure the long term. When researchers boosted these channels of energy in mice, the T-cells killed tumor cells better and produced higher levels of interferon-γ, an immune
December 9, 2025 at 5:05 PM
glycolysis, they switched to oxidative phosphorylation and fatty acid metabolism- an energy strategy that enables them to endure the long term. When researchers boosted these channels of energy in mice, the T-cells killed tumor cells better and produced higher levels of interferon-γ, an immune
Reposted by AnHoi
single-cell resolution, the researchers identified a minor subset of tumor-cytotoxic cells. These cells continue to function even in oxygen-starved, nutrient-poor environments in which other immune cells do not. These hardy T-cells employed a second fuel source. Instead of combusting glucose through
December 9, 2025 at 5:05 PM
single-cell resolution, the researchers identified a minor subset of tumor-cytotoxic cells. These cells continue to function even in oxygen-starved, nutrient-poor environments in which other immune cells do not. These hardy T-cells employed a second fuel source. Instead of combusting glucose through
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patients, the treatments fail because immune cells become exhausted. Tumors naturally adapt to disable or tire out the same cells meant to kill them. Researchers mapped how CD8⁺ T cells-the body's own killers-are capable of surviving and fighting within solid tumors. By examining the cells at
December 9, 2025 at 5:04 PM
patients, the treatments fail because immune cells become exhausted. Tumors naturally adapt to disable or tire out the same cells meant to kill them. Researchers mapped how CD8⁺ T cells-the body's own killers-are capable of surviving and fighting within solid tumors. By examining the cells at
Reposted by AnHoi
place. Taken together, the breakthroughs promise a day when the body's own immune system can prevent and fight cancer with greater accuracy and endurance. Cancer immunotherapy transformed the treatment of most cancers by unleashing the potential of the immune system to kill tumors. Yet, in most
December 9, 2025 at 5:04 PM
place. Taken together, the breakthroughs promise a day when the body's own immune system can prevent and fight cancer with greater accuracy and endurance. Cancer immunotherapy transformed the treatment of most cancers by unleashing the potential of the immune system to kill tumors. Yet, in most
Reposted by AnHoi
In a breakthrough that could potentially rewrite the prevention and treatment of cancer, researchers have discovered how certain immune cells can break through tumors’ defenses. They have also developed a new nanoscale vaccine that shows promise in preventing cancers from occurring in the first
December 9, 2025 at 5:03 PM
In a breakthrough that could potentially rewrite the prevention and treatment of cancer, researchers have discovered how certain immune cells can break through tumors’ defenses. They have also developed a new nanoscale vaccine that shows promise in preventing cancers from occurring in the first
Reposted by AnHoi
Melanoma, pancreatic cancer, and triple-negative breast cancer (TNBC) are each serious clinical challenges due to how common or aggressive they are and how poorly they often respond to treatment. Which is why researchers are determined to develop an effective treatment for all of them.
December 9, 2025 at 5:03 PM
Melanoma, pancreatic cancer, and triple-negative breast cancer (TNBC) are each serious clinical challenges due to how common or aggressive they are and how poorly they often respond to treatment. Which is why researchers are determined to develop an effective treatment for all of them.