@andreichabes.bsky.social
New research from our lab on mitochondrial DNA stability
RRM2B is essential for making dNTPs in non-dividing cells and its loss causes mt DNA depletion syndromes.
Surprisingly, we found that RRM2B deficiency leads to a drop in dATP and dGTP.
www.pnas.org/doi/10.1073/...
RRM2B is essential for making dNTPs in non-dividing cells and its loss causes mt DNA depletion syndromes.
Surprisingly, we found that RRM2B deficiency leads to a drop in dATP and dGTP.
www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
April 21, 2025 at 12:17 PM
New research from our lab on mitochondrial DNA stability
RRM2B is essential for making dNTPs in non-dividing cells and its loss causes mt DNA depletion syndromes.
Surprisingly, we found that RRM2B deficiency leads to a drop in dATP and dGTP.
www.pnas.org/doi/10.1073/...
RRM2B is essential for making dNTPs in non-dividing cells and its loss causes mt DNA depletion syndromes.
Surprisingly, we found that RRM2B deficiency leads to a drop in dATP and dGTP.
www.pnas.org/doi/10.1073/...