Amber Luckett
@ambermluckett.bsky.social
PhD student researching Type 1 Diabetes genetics @ University of Exeter 🧬🌊
Our new preprint is now available on medRxiv! 🎉
Genetic association of T1D stratified by HLA DR3 and DR4 status reveals heterogeneity in pathways of progression to T1D
🔗 tinyurl.com/3fr2kcny
A huge thank you to all involved!🧬
#type1diabetes #genetics #type1diabetesresearch #preprint
Genetic association of T1D stratified by HLA DR3 and DR4 status reveals heterogeneity in pathways of progression to T1D
🔗 tinyurl.com/3fr2kcny
A huge thank you to all involved!🧬
#type1diabetes #genetics #type1diabetesresearch #preprint
Genetic association of T1D stratified by HLA DR3 and DR4 status reveals heterogeneity in pathways of progression to T1D
Background There are substantial differences in the clinical presentation of type 1 diabetes (T1D) depending on the first-developing autoantibody, although the underlying mechanisms are poorly underst...
www.medrxiv.org
August 18, 2025 at 3:44 PM
Our new preprint is now available on medRxiv! 🎉
Genetic association of T1D stratified by HLA DR3 and DR4 status reveals heterogeneity in pathways of progression to T1D
🔗 tinyurl.com/3fr2kcny
A huge thank you to all involved!🧬
#type1diabetes #genetics #type1diabetesresearch #preprint
Genetic association of T1D stratified by HLA DR3 and DR4 status reveals heterogeneity in pathways of progression to T1D
🔗 tinyurl.com/3fr2kcny
A huge thank you to all involved!🧬
#type1diabetes #genetics #type1diabetesresearch #preprint
Reposted by Amber Luckett
Interesting finding from @ambermluckett.bsky.social - the non-HLA GWAS of HLA DR3+ and DR4+ type 1 diabetes are surprisingly different (coheritability is only 0.68). Some evidence of less adaptive (CD4) and more innate (mast cell) enrichment in DR3 genetics. #eshg2025
May 24, 2025 at 9:20 AM
Interesting finding from @ambermluckett.bsky.social - the non-HLA GWAS of HLA DR3+ and DR4+ type 1 diabetes are surprisingly different (coheritability is only 0.68). Some evidence of less adaptive (CD4) and more innate (mast cell) enrichment in DR3 genetics. #eshg2025
Reposted by Amber Luckett
Got a big showing of talented University of Exeter scientists with talks and posters at ESHG25 in Milan. Come along and find out more! @hls.exeter.ac.uk @exeter.ac.uk #ESHG25 @jamesfasham.bsky.social @jingzhan.bsky.social @ambermluckett.bsky.social @chundru.bsky.social @harrygreentkd.bsky.social
May 23, 2025 at 12:08 PM
Got a big showing of talented University of Exeter scientists with talks and posters at ESHG25 in Milan. Come along and find out more! @hls.exeter.ac.uk @exeter.ac.uk #ESHG25 @jamesfasham.bsky.social @jingzhan.bsky.social @ambermluckett.bsky.social @chundru.bsky.social @harrygreentkd.bsky.social
Our new paper updating GRS2 with a new tool to easily generate standardised T1DGRS 🧬 Thanks to Seth Sharp, @annagloyn.bsky.social, Richard Oram and @mnweedon.bsky.social for a great collaboration! tinyurl.com/4bsaz9hx
Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multiancestry Population Cohorts
Amber M. Luckett, Richard A. Oram, Aaron J. Deutsch, Hector I. Ortega, Diane P. Fraser, Kaavya Ashok, Alisa K. Manning, Josep M. Mercader, Manuel A. Rivas,
tinyurl.com
April 25, 2025 at 10:44 AM
Our new paper updating GRS2 with a new tool to easily generate standardised T1DGRS 🧬 Thanks to Seth Sharp, @annagloyn.bsky.social, Richard Oram and @mnweedon.bsky.social for a great collaboration! tinyurl.com/4bsaz9hx