Ali Altıntaş
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altintasali.bsky.social
Ali Altıntaş
@altintasali.bsky.social
Assistant Professor, University of Copenhagen 🇩🇰 | #Bioinformatician | #Molecular #Biologist | Forged in 🇹🇷
🌍 Excited to be part of this global effort! 🦠

Microbial and metabolic diversity was mapped across 51 vivaria & 12 wild colonies, revealing striking functional convergence despite taxonomic divergence.

🔗 www.cell.com/cell-host-mi...
November 10, 2025 at 1:39 PM
🚨 Dealing with sparse, noisy single-cell DNA methylation data (scBS-seq)? Check out #scDMV.

It uses a zero-one inflated beta mixture model to tackle the excess of 0s/1s and low coverage, boosting accuracy in identifying differentially methylated regions (DMRs).
scDMV: a zero–one inflated beta mixture model for DNA methylation variability with scBS-seq data
AbstractMotivation. The utilization of single-cell bisulfite sequencing (scBS-seq) methods allows for precise analysis of DNA methylation patterns at the i
academic.oup.com
October 20, 2025 at 11:35 AM
On the art of great article titles: this one’s dedicated to all the Reviewer 2s out there.

🔗 onlinelibrary.wiley.com/doi/10.1111/...
September 5, 2025 at 11:47 AM
❓ How do you know if a gene is expressed or not in a certain tissue/organ?

👉 If you are interested in animals, #Bgee database is the first place to go. 52 species, several tissues/organs...

www.bgee.org
August 26, 2025 at 12:22 PM
Before running your statistical test, double-check that its assumptions hold. Violations can lead to misleading results. Here's a handy tool to help:

🔗 ahmed-bargheet.shinyapps.io/AssumpSure
ℹ️ github.com/Ahmedbarghee...

#rstats #shiny #r
August 11, 2025 at 1:07 PM
"A drunk man will find his way home, but a drunk bird may get lost forever." -Shizuo Kakutani
August 5, 2025 at 12:24 PM
🚨Our latest: HIF1α mediates circadian regulation of skeletal muscle metabolism and substrate preference in response to time-of-day exercise ⏰💪
📄 www.pnas.org/doi/10.1073/...
August 1, 2025 at 12:44 PM
A nice #R package to visualize #bullseye plots:
🔗 cran.r-project.org/web/packages...

❓ Did you notice the Simpson's paradox?
May 28, 2025 at 1:43 PM
Are you developing an R package? Great tips ahead ⬇️

journals.plos.org/ploscompbiol...
Eleven quick tips for writing a Bioconductor package
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journals.plos.org
May 19, 2025 at 2:23 PM
📢 RNA-seq users! RPKM/TPM are NOT always comparable across samples/projects. They're relative within a sample. rnajournal.cshlp.org/content/26/8...
April 7, 2025 at 11:27 AM