Alex K
@alexkzis.bsky.social
Researcher in #platelets #cytoskeleton regulation #PTM modifications #teaching #Trailrunning #pastries #food #Paris #trips #lgbtqia+ #he #him #puglover & 🏳️🌈
Excited to share that our paper is out in @natcomms.nature.com
🔗 rdcu.be/ez3Gt
We uncover how MICAL1 regulates actin dynamics to enhance VWF–GPIbα binding in platelets.
Big thanks to all co-authors & collaborators !
@hithlabinserm1176.bsky.social @echardlab-pasteur.bsky.social
🔗 rdcu.be/ez3Gt
We uncover how MICAL1 regulates actin dynamics to enhance VWF–GPIbα binding in platelets.
Big thanks to all co-authors & collaborators !
@hithlabinserm1176.bsky.social @echardlab-pasteur.bsky.social
F-actin disassembly by the oxidoreductase MICAL1 promotes mechano-dependent VWF-GPIbα interaction in platelets
Nature Communications - To stop bleeding from an injured vessel, platelets adhere and form a clot despite high shear stress from the flow. Here, the authors show that platelet actin disassembly is...
rdcu.be
August 12, 2025 at 9:47 AM
Excited to share that our paper is out in @natcomms.nature.com
🔗 rdcu.be/ez3Gt
We uncover how MICAL1 regulates actin dynamics to enhance VWF–GPIbα binding in platelets.
Big thanks to all co-authors & collaborators !
@hithlabinserm1176.bsky.social @echardlab-pasteur.bsky.social
🔗 rdcu.be/ez3Gt
We uncover how MICAL1 regulates actin dynamics to enhance VWF–GPIbα binding in platelets.
Big thanks to all co-authors & collaborators !
@hithlabinserm1176.bsky.social @echardlab-pasteur.bsky.social
Farewell party for Jean. End of an amazing PhD and the beginning of a new story in @immunothrombosis.bsky.social lab in Munich. #research #phd #postdoc #mentorship
June 27, 2025 at 4:37 PM
Farewell party for Jean. End of an amazing PhD and the beginning of a new story in @immunothrombosis.bsky.social lab in Munich. #research #phd #postdoc #mentorship
A special day: Jean Solarz, my first PhD student, successfully defended his thesis. Proud of all the work accomplished! Thks to jury members.
Huge congratulations to Dr Jean Solarz for brilliantly defending his PhD today! And to his supervisors @alexkzis.bsky.social and Frederic Adam.
We are very proud of you!
A big thank you to all the committee members Prof N Ajzenberg, Dr MP Gratacap, Dr G Romet-Lemonne, Dr Leon, and Dr Ho-Tin-Noe
We are very proud of you!
A big thank you to all the committee members Prof N Ajzenberg, Dr MP Gratacap, Dr G Romet-Lemonne, Dr Leon, and Dr Ho-Tin-Noe
June 5, 2025 at 7:46 PM
A special day: Jean Solarz, my first PhD student, successfully defended his thesis. Proud of all the work accomplished! Thks to jury members.
Bravo Jean Solarz for your presentation at the French Society of Hematology on MICAL1 @hithlabinserm1176.bsky.social #sfh #Hemsky #hemesky
April 4, 2025 at 8:57 AM
Bravo Jean Solarz for your presentation at the French Society of Hematology on MICAL1 @hithlabinserm1176.bsky.social #sfh #Hemsky #hemesky
Reposted by Alex K
We have worked for 2 years with @dianvanderwaldr.bsky.social to propose a protocol for platelet desialylation, and we are excited to now share it. Communication from the ISTH SSC Platelet Physiology. - Journal of Thrombosis and Haemostasis www.jthjournal.org/article/S153... #hemsky #hemesky
Consensus protocol for platelet desialylation (β-galactose exposure) quantification using lectins by flow cytometry: Communication from the ISTH SSC Subcommittee on Platelet Physiology.
Platelets contain many heterogeneous carbohydrates (glycans): often capped by sialic
acid. The removal of sialic acid (desialylation) is important for platelet function
and clearance, leading to novel...
www.jthjournal.org
March 25, 2025 at 7:59 PM
We have worked for 2 years with @dianvanderwaldr.bsky.social to propose a protocol for platelet desialylation, and we are excited to now share it. Communication from the ISTH SSC Platelet Physiology. - Journal of Thrombosis and Haemostasis www.jthjournal.org/article/S153... #hemsky #hemesky
Consensus protocol for platelet desialylation (β-galactose exposure) quantification using lectins by flow cytometry: Communication from the ISTH SSC Subcommittee on Platelet Physiology.
Platelets contain many heterogeneous carbohydrates (glycans): often capped by sialic
acid. The removal of sialic acid (desialylation) is important for platelet function
and clearance, leading to novel...
www.jthjournal.org
March 25, 2025 at 5:07 PM
We have worked for 2 years with @dianvanderwaldr.bsky.social to propose a protocol for platelet desialylation, and we are excited to now share it. Communication from the ISTH SSC Platelet Physiology. - Journal of Thrombosis and Haemostasis www.jthjournal.org/article/S153... #hemsky #hemesky
Finisher of Ecotrail of Paris, 46 km! Château de Versailles->Tour Eiffel #Ecotrail #paris #trail #trailerunning #ecotrailparis
March 22, 2025 at 4:37 PM
Finisher of Ecotrail of Paris, 46 km! Château de Versailles->Tour Eiffel #Ecotrail #paris #trail #trailerunning #ecotrailparis
Great collaboration with Hana Raslova and @alessandrabalduini.bsky.social teams on BSS signaling defect! Recently published. @hithlabinserm1176.bsky.social
haematologica.org/article/view...
haematologica.org/article/view...
Early View
| Haematologica
haematologica.org
March 19, 2025 at 2:44 PM
Great collaboration with Hana Raslova and @alessandrabalduini.bsky.social teams on BSS signaling defect! Recently published. @hithlabinserm1176.bsky.social
haematologica.org/article/view...
haematologica.org/article/view...
Reposted by Alex K
In the @hithlabinserm1176.bsky.social we love to collaborate! Check out this very interesting paper by @Prof Elisa Rossi with valuable contributions by @alexkzis.bsky.social and @ceciledenis.bsky.social from our group!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Thrombin cleaves membrane-bound endoglin potentially contributing to the heterogeneity of circulating endoglin in preeclampsia - Communications Biology
Thrombin cleaves membrane-bound endoglin and soluble endoglin, releasing fragments of varying sizes; these findings emphasize the heterogeneity of sEng in preeclampsia, connecting endothelial dysfunct...
www.nature.com
March 3, 2025 at 11:47 PM
In the @hithlabinserm1176.bsky.social we love to collaborate! Check out this very interesting paper by @Prof Elisa Rossi with valuable contributions by @alexkzis.bsky.social and @ceciledenis.bsky.social from our group!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Alex K
Great presention of Caterina Casari during the #GTH2025 on SynthoPlates. When art meets science. 🇨🇭 @caterinacasari.bsky.social #womeninscience #synthoplates
February 21, 2025 at 11:42 AM
Great presention of Caterina Casari during the #GTH2025 on SynthoPlates. When art meets science. 🇨🇭 @caterinacasari.bsky.social #womeninscience #synthoplates
Reposted by Alex K
👏An incredible session by 3 incredible women during the #gth2025 with Alessandra Balduini on Red blood cells prod, Catherine Strassel on platelet prod and Caterina Casari with bioinspired platelets. @alessandrabalduini.bsky.social @caterinacasari.bsky.social
February 21, 2025 at 11:47 AM
👏An incredible session by 3 incredible women during the #gth2025 with Alessandra Balduini on Red blood cells prod, Catherine Strassel on platelet prod and Caterina Casari with bioinspired platelets. @alessandrabalduini.bsky.social @caterinacasari.bsky.social
Reposted by Alex K
The lab is at #GTH2025 in Lausanne with Caterina, Jean and Alex! Jean has already presented his study, but don't miss Caterina tomorrow with the SynthoPlates! @caterinacasari.bsky.social @alexkzis.bsky.social #Science #congress #switzerland
February 20, 2025 at 5:42 PM
The lab is at #GTH2025 in Lausanne with Caterina, Jean and Alex! Jean has already presented his study, but don't miss Caterina tomorrow with the SynthoPlates! @caterinacasari.bsky.social @alexkzis.bsky.social #Science #congress #switzerland
Reposted by Alex K
🚨BREAKING. From a program officer at the National Science Foundation, a list of keywords that can cause a grant to be pulled. I will be sharing screenshots of these keywords along with a decision tree. Please share widely. This is a crisis for academic freedom & science.
February 4, 2025 at 1:26 AM
🚨BREAKING. From a program officer at the National Science Foundation, a list of keywords that can cause a grant to be pulled. I will be sharing screenshots of these keywords along with a decision tree. Please share widely. This is a crisis for academic freedom & science.
Super talk of Stephan Schiffels from Max Planck Institute during the #GTH congress. We are all a mix from our genetic heritage and immigration ! @mpimmg.bsky.social #freedom #immigration
@stschiff.ecoevo.social.ap.brid.gy
@stschiff.ecoevo.social.ap.brid.gy
February 20, 2025 at 9:21 AM
Super talk of Stephan Schiffels from Max Planck Institute during the #GTH congress. We are all a mix from our genetic heritage and immigration ! @mpimmg.bsky.social #freedom #immigration
@stschiff.ecoevo.social.ap.brid.gy
@stschiff.ecoevo.social.ap.brid.gy
Reposted by Alex K
The SFTH is thrilled to support young researchers to attend conferences. We believe in fostering the next generation of researchers. #GTH #u1176 @hithlabinserm1176.bsky.social
February 19, 2025 at 7:47 AM
The SFTH is thrilled to support young researchers to attend conferences. We believe in fostering the next generation of researchers. #GTH #u1176 @hithlabinserm1176.bsky.social
Reposted by Alex K
Great presentation by PhD student Jean Solarz at #GTH2025 in Lausanne this morning! We are very proud of you!
@alexkzis.bsky.social @hithlabinserm1176.bsky.social
@alexkzis.bsky.social @hithlabinserm1176.bsky.social
February 19, 2025 at 7:35 AM
Great presentation by PhD student Jean Solarz at #GTH2025 in Lausanne this morning! We are very proud of you!
@alexkzis.bsky.social @hithlabinserm1176.bsky.social
@alexkzis.bsky.social @hithlabinserm1176.bsky.social
Trail running training of 23km in the Fontainebleau forest and castle! #trail #trailrunning
February 16, 2025 at 1:38 PM
Trail running training of 23km in the Fontainebleau forest and castle! #trail #trailrunning
Reposted by Alex K
Join the SFTH 2025 Congress
Now’s your time to shine!
Abstract submissions for the SFTH 2025 Congress are officially open! Don’t miss the chance to showcase your research and innovations to the community.
Submit your work now, here:
www.congres-hemostase.com/abstracts/
Deadline April 25, 2025.
Now’s your time to shine!
Abstract submissions for the SFTH 2025 Congress are officially open! Don’t miss the chance to showcase your research and innovations to the community.
Submit your work now, here:
www.congres-hemostase.com/abstracts/
Deadline April 25, 2025.
February 9, 2025 at 7:26 PM
Join the SFTH 2025 Congress
Now’s your time to shine!
Abstract submissions for the SFTH 2025 Congress are officially open! Don’t miss the chance to showcase your research and innovations to the community.
Submit your work now, here:
www.congres-hemostase.com/abstracts/
Deadline April 25, 2025.
Now’s your time to shine!
Abstract submissions for the SFTH 2025 Congress are officially open! Don’t miss the chance to showcase your research and innovations to the community.
Submit your work now, here:
www.congres-hemostase.com/abstracts/
Deadline April 25, 2025.
Reposted by Alex K
Our colleague @alexkzis.bsky.social was invited by #RFTH Hémostase for the annual “best of hemostasis 2024” webtv show with our friends @cedrichermans.bsky.social Annabelle Dupont, Patrick Mismetti & Yves Gruel!
Very proud to be invited to the RFHT journal for the Year of hemostasis. Was an amazing experience. #rfht
February 4, 2025 at 6:49 PM
Our colleague @alexkzis.bsky.social was invited by #RFTH Hémostase for the annual “best of hemostasis 2024” webtv show with our friends @cedrichermans.bsky.social Annabelle Dupont, Patrick Mismetti & Yves Gruel!
Dear Colleagues in the USA,
We wish to express our unwavering support for you during these alarming times. Read the letter here:
rogueesr.fr/in-solidarity/
#rogueesr
We wish to express our unwavering support for you during these alarming times. Read the letter here:
rogueesr.fr/in-solidarity/
#rogueesr
In solidarity
In solidarity Dear Colleagues in the USA, We wish to express our unwavering support for you during these alarming times. From our positions as researchers and academics in Europe, we are observing …
rogueesr.fr
February 2, 2025 at 8:06 PM
Dear Colleagues in the USA,
We wish to express our unwavering support for you during these alarming times. Read the letter here:
rogueesr.fr/in-solidarity/
#rogueesr
We wish to express our unwavering support for you during these alarming times. Read the letter here:
rogueesr.fr/in-solidarity/
#rogueesr
February 1, 2025 at 4:51 PM