Alexandre Paix
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alexandrepaix83.bsky.social
Alexandre Paix
@alexandrepaix83.bsky.social
Biological Engineering and Developmental Biology scientist

Algae genetics, genome engineering across biological models, promoting alternative organisms with collaboration and mentoring.

Max Planck Institute for Biology Tübingen
@MPI_bio
C. Elegans had been a crucial model for my growth as a scientist. After my PhD in a limited genetically tractable model, I learnt genetics in a great worm lab. Since then, these lessons have been applied to non-mainstream models, always keeping in mind C. Elegans as an example
January 25, 2026 at 11:21 AM
Amazing collaboration with Jordi van Gestel group and EMBL colleagues, or how great work is done when the right persons meet . And congrats to the first author Mireia Garriga-Canut. Bringing straightforward genetic tools to Dictyostelids, and Cas9 RNP optimization

link.springer.com/article/10.1...
Unlocking CRISPR-Cas9 editing for widely diverse Dictyostelid species - Molecular Systems Biology
Dictyostelids are a species-rich clade of cellular slime molds that are widely found in soils and have been studied for over a century. Due to a lack of genome editing methods, most molecular research...
link.springer.com
January 15, 2026 at 10:44 PM
Reposted by Alexandre Paix
Just making sure that 2025 is definitely over
January 1, 2026 at 4:43 AM
I like that Development journal does these interviews, specially when it is about good scientists and good people
journals.biologists.com/dev/article/...
The people behind the papers – Agnès Roure and Sébastien Darras
In animals, species-specific organs and nervous systems are patterned from the developing neuroectoderm by conserved canonical Wnt signals. However, how these developmental trajectories diverged throu...
journals.biologists.com
December 14, 2025 at 12:59 PM
Reposted by Alexandre Paix
Thinking about a PhD and excited by algal development and evolution? 🌿🧬
Our IMPRS program has an open doctoral position in the department of Susana Coelho.
More projects will be posted soon, so keep an eye on the page—or browse the current list here:
lnkd.in/gEMXNQY6
Deadline: 19 January 2026
December 10, 2025 at 8:14 AM
Pleased to be again a trainer for the EMBO Practical Course: C. elegans, from genome editing to imaging.

Register if you want to learn about (one of) the best model organism for genetics and imaging

www.embl.org/about/info/c...

#EMBOCelegans
C. elegans: from genome editing to imaging
www.embl.org
October 22, 2025 at 9:14 AM
Happy to share our last protocol for efficient endogenous gene tagging in Medaka. We hope this will encourage genetic and imaging approaches in other non-conventional fish models. A big thank you to all co-authors, and congrats to the first author Simon Knoblich
bio-protocol.org/en/bpdetail?...
bio-protocol.org
July 28, 2025 at 9:46 AM
Reposted by Alexandre Paix
Have you used our datasets, atlases, protocols, cell lines, and other #OpenScience resources in your research or classroom?

Tell us about it! Share your story with us at bit.ly/opensciences...

Select stories will be shared on our social media channels during #OpenScienceWeek.
April 4, 2025 at 7:19 PM
Our effort to extend genome editing across species just got a new member. This time, not a marine organism, nor a vertebrate, but the beautiful Dictyostelium discoideum and other Dictyostelids. In collaboration with van Gestel group
@jordivangestel.bsky.social

www.biorxiv.org/content/10.1...
Selection-free CRISPR-Cas9 editing protocol for distant Dictyostelid species
Dictyostelids are a species-rich clade of cellular slime molds that are widely found in soils and have been studied for over a century. Most research focusses on Dictyostelium discoideum , which – due...
www.biorxiv.org
March 27, 2025 at 3:21 PM
Finally decided to migrate from X to Bluesky
March 26, 2025 at 8:15 PM