Alexander Titus
@alexandertitus.com
Scientist, Sci-Fi Author, and Tech Nerd wandering the world. Obsessed with #biotech, #AI, and frontier tech.
Join me @ connectedideasproject.com for thoughts on tech, policy, and life.
Join me @ connectedideasproject.com for thoughts on tech, policy, and life.
The era of Scientific Superintelligence is here. From the 2012 publication of CRISRP and AlexNet, to the 2022 release of ChatGPT-3, the next decade will reimagine the paradigm of the scientific method. Aligned Accelerated Discovery.
#AI #Biotech
www.connectedideasproject.com/p/ep-51-teac...
#AI #Biotech
www.connectedideasproject.com/p/ep-51-teac...
Ep 51 - Teaching Science to Know Itself
The coming age of scientific superintelligence and the technologies that will make it possible
www.connectedideasproject.com
October 21, 2025 at 12:38 PM
The era of Scientific Superintelligence is here. From the 2012 publication of CRISRP and AlexNet, to the 2022 release of ChatGPT-3, the next decade will reimagine the paradigm of the scientific method. Aligned Accelerated Discovery.
#AI #Biotech
www.connectedideasproject.com/p/ep-51-teac...
#AI #Biotech
www.connectedideasproject.com/p/ep-51-teac...
"EoT hits its stride in Book 2. I found myself caring much more about the next generation of the colony. But most surprisingly, drawn to Lucas...You'll have to read...to find out what I mean...I didn't know I could or would ever care about what happens to an AI." 😍
www.amazon.com/gp/product/B...
www.amazon.com/gp/product/B...
Hubris Rising (Echoes of Tomorrow Book 2)
Hubris Rising (Echoes of Tomorrow Book 2) - Kindle edition by Titus, Alexander, Platt, Sean. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Hubris Rising (Echoes of Tomorrow Book 2).
www.amazon.com
October 13, 2025 at 10:26 AM
"EoT hits its stride in Book 2. I found myself caring much more about the next generation of the colony. But most surprisingly, drawn to Lucas...You'll have to read...to find out what I mean...I didn't know I could or would ever care about what happens to an AI." 😍
www.amazon.com/gp/product/B...
www.amazon.com/gp/product/B...
Today is the launch of my debut novel! The early feedback for Synthetic Eden has been amazing and humbling. This project was as much a collaboration with my community as it was with my co-author Sean and our editor Bonnie.
www.connectedideasproject.com/p/ep-50-mora...
www.connectedideasproject.com/p/ep-50-mora...
Ep 50 - Moral World Building and the Launch of a New Partnership
I brought the science, and Sean brought the fiction. How a novel partnership built Synthetic Eden into a hard science fiction take on modern bioethics and genetic engineering.
www.connectedideasproject.com
September 9, 2025 at 12:38 PM
Today is the launch of my debut novel! The early feedback for Synthetic Eden has been amazing and humbling. This project was as much a collaboration with my community as it was with my co-author Sean and our editor Bonnie.
www.connectedideasproject.com/p/ep-50-mora...
www.connectedideasproject.com/p/ep-50-mora...
Yesterday marked a milestone: My debut novel, Synthetic Eden, officially went live for pre-order, and within twenty-four hours, it climbed into the top 500 #GeneticEngineering #SciFi books on Amazon! For context, #1 is Brave New World, so we're in good company 😱
www.amazon.com/Synthetic-Ed...
www.amazon.com/Synthetic-Ed...
Synthetic Eden (Echoes of Tomorrow Book 1)
Synthetic Eden (Echoes of Tomorrow Book 1) - Kindle edition by Titus, Alexander, Platt, Sean. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Synthetic Eden (Echoes of Tomorrow Book 1).
www.amazon.com
September 3, 2025 at 3:29 PM
Yesterday marked a milestone: My debut novel, Synthetic Eden, officially went live for pre-order, and within twenty-four hours, it climbed into the top 500 #GeneticEngineering #SciFi books on Amazon! For context, #1 is Brave New World, so we're in good company 😱
www.amazon.com/Synthetic-Ed...
www.amazon.com/Synthetic-Ed...
We define "species" with relatively artificial definitions because we don't have a better way to do so, but we keep getting schooled on our own ignorance. It's wild to keep watching :-P
What is life? Heck if I know!
#genomics #evolution
www.connectedideasproject.com/p/ep-49-mamm...
What is life? Heck if I know!
#genomics #evolution
www.connectedideasproject.com/p/ep-49-mamm...
Ep 49 - Mammoths, Moonshots, and the Messiness of Life
What the discovery of a new mammoth lineage in Mexico teaches us about the shifting paradigms of life
www.connectedideasproject.com
September 3, 2025 at 12:38 PM
We define "species" with relatively artificial definitions because we don't have a better way to do so, but we keep getting schooled on our own ignorance. It's wild to keep watching :-P
What is life? Heck if I know!
#genomics #evolution
www.connectedideasproject.com/p/ep-49-mamm...
What is life? Heck if I know!
#genomics #evolution
www.connectedideasproject.com/p/ep-49-mamm...
As someone who started a career in AIxBio with highly specialized models a decade ago, I find it funny that we're now coming back full circle. One model to rule them all is proving wrong, but the impact of this new era of specialization is mindblowing.
www.connectedideasproject.com/p/ep-48-the-...
www.connectedideasproject.com/p/ep-48-the-...
Ep 48 - The Model That Reprograms Cells
How specialized AI models are rewriting the code of cell identity and accelerating regenerative biology
www.connectedideasproject.com
August 26, 2025 at 12:38 PM
As someone who started a career in AIxBio with highly specialized models a decade ago, I find it funny that we're now coming back full circle. One model to rule them all is proving wrong, but the impact of this new era of specialization is mindblowing.
www.connectedideasproject.com/p/ep-48-the-...
www.connectedideasproject.com/p/ep-48-the-...
Seven moonshots that define the century of biology. From cracking the code of life to building resilient bio-infrastructure, these challenges aren’t just about #science—they’re about how we thrive forward. #biotech
www.connectedideasproject.com/p/ep-47-seve...
www.connectedideasproject.com/p/ep-47-seve...
Ep 47 - Seven Moonshots for the Century of Biology
From decoding life to redesigning society, the moonshots that chart our biological future
www.connectedideasproject.com
August 19, 2025 at 12:38 PM
Seven moonshots that define the century of biology. From cracking the code of life to building resilient bio-infrastructure, these challenges aren’t just about #science—they’re about how we thrive forward. #biotech
www.connectedideasproject.com/p/ep-47-seve...
www.connectedideasproject.com/p/ep-47-seve...
Advance reader copies of Synthetic Eden are going out soon. Join me to help make this launch awesome!
#ScienceFiction #Biotechnology #SciFi
www.connectedideasproject.com/p/synthetic-...
#ScienceFiction #Biotechnology #SciFi
www.connectedideasproject.com/p/synthetic-...
Synthetic Eden ARCs are dropping soon - sign up before they close
You are the why I write this newsletter, and I'd like to say thank you with an advanced reader copy of my debut novel. You helped make this a reality, so be one of the first to read the story.
www.connectedideasproject.com
August 15, 2025 at 12:38 PM
Advance reader copies of Synthetic Eden are going out soon. Join me to help make this launch awesome!
#ScienceFiction #Biotechnology #SciFi
www.connectedideasproject.com/p/synthetic-...
#ScienceFiction #Biotechnology #SciFi
www.connectedideasproject.com/p/synthetic-...
We no longer have the luxury of academic debates about the ethics of embryo and human genetic engineering. The first company was founded with this explicit mission and launched last week. Where do we go from here?
#biotechnology #bioethics #biotech
www.connectedideasproject.com/p/ep-46-manh...
#biotechnology #bioethics #biotech
www.connectedideasproject.com/p/ep-46-manh...
Ep 46 - Manhattan Genomics and the Kobayashi Maru of Biology
At the frontier of technology, humanity is the experiment. The question now is, who is designing the experiment?
www.connectedideasproject.com
August 12, 2025 at 12:38 PM
We no longer have the luxury of academic debates about the ethics of embryo and human genetic engineering. The first company was founded with this explicit mission and launched last week. Where do we go from here?
#biotechnology #bioethics #biotech
www.connectedideasproject.com/p/ep-46-manh...
#biotechnology #bioethics #biotech
www.connectedideasproject.com/p/ep-46-manh...
I'm looking for sci-fi nerds interested in being advance readers for my debut novel! All it costs is an honest review on launch day! (9/9)
www.connectedideasproject.com/p/synthetic-...
#SciFi #Biotech #Fiction
www.connectedideasproject.com/p/synthetic-...
#SciFi #Biotech #Fiction
Synthetic Eden is Coming — ARC Readers Wanted
Join me for an advanced reader copy of Synthetic Eden and be one of the first in the world to read my full debut novel
www.connectedideasproject.com
August 8, 2025 at 4:13 PM
I'm looking for sci-fi nerds interested in being advance readers for my debut novel! All it costs is an honest review on launch day! (9/9)
www.connectedideasproject.com/p/synthetic-...
#SciFi #Biotech #Fiction
www.connectedideasproject.com/p/synthetic-...
#SciFi #Biotech #Fiction
How about a positive vision for FDA in the midst of the chaos?
www.connectedideasproject.com/p/invisible-...
www.connectedideasproject.com/p/invisible-...
Invisible Hands
Today, an entire submission for a new gene therapy had been reviewed in under four hours
substack.com
April 4, 2025 at 3:26 PM
How about a positive vision for FDA in the midst of the chaos?
www.connectedideasproject.com/p/invisible-...
www.connectedideasproject.com/p/invisible-...
I wanted to take a minute to share a more narrative perspective on the importance of biotech in the modern era.
www.connectedideasproject.com/p/ep-30-the-...
www.connectedideasproject.com/p/ep-30-the-...
Ep 30 - The Next National Security Race: How Biotech is Rewriting Global Power
A primer on the growing importance of biotechnology in the 21st century intended to be a complement to the upcoming final report of the U.S. National Security Commission on Emerging Biotechnology
www.connectedideasproject.com
April 1, 2025 at 4:43 PM
I wanted to take a minute to share a more narrative perspective on the importance of biotech in the modern era.
www.connectedideasproject.com/p/ep-30-the-...
www.connectedideasproject.com/p/ep-30-the-...
Thoughts and summary of the recent NASEM report on AI and biosecurity
www.connectedideasproject.com/p/ep-28-the-...
www.connectedideasproject.com/p/ep-28-the-...
Ep 28 - The Real Risks, and Real Promise, of AI in Biotech from the Perspective of the National Academies
As someone who sat on the National Academies’ study committee on AI and Biosecurity, I can tell you: the truth is neither so dire nor so utopian.
www.connectedideasproject.com
March 18, 2025 at 2:11 PM
Thoughts and summary of the recent NASEM report on AI and biosecurity
www.connectedideasproject.com/p/ep-28-the-...
www.connectedideasproject.com/p/ep-28-the-...
Reposted by Alexander Titus
Useful critique of the biosecurity risk assessment process, as applied to mirror life based on our experience with synbio, genome editing, and AI, by @alexandertitus.com
The Mirror Life Problem: When Every Threat Looks Like the Next Existential Crisis
www.connectedideasproject.com/p/ep-28-the-...
The Mirror Life Problem: When Every Threat Looks Like the Next Existential Crisis
www.connectedideasproject.com/p/ep-28-the-...
Ep 27 - The Mirror Life Problem: When Every Threat Looks Like the Next Existential Crisis
I have no doubt that mirror life will continue to be a topic of interest in synthetic biology and biosecurity circles. But I am not ready to buy into the panic just yet.
www.connectedideasproject.com
March 11, 2025 at 12:24 PM
Useful critique of the biosecurity risk assessment process, as applied to mirror life based on our experience with synbio, genome editing, and AI, by @alexandertitus.com
The Mirror Life Problem: When Every Threat Looks Like the Next Existential Crisis
www.connectedideasproject.com/p/ep-28-the-...
The Mirror Life Problem: When Every Threat Looks Like the Next Existential Crisis
www.connectedideasproject.com/p/ep-28-the-...
In the world of dual-use and dual-hype, the #AI and #biotech debate reigns supreme. But a recent report by Epoch AI shows that the progress is moderating and evolving. I think we're maturing into actual use-cases that are demonstrating impact.
www.connectedideasproject.com/p/ep-26-the-...
www.connectedideasproject.com/p/ep-26-the-...
Ep 26 - The Slowdown in AI for Biology: A Pause or a Plateau?
AI-driven breakthroughs were piling up so fast it felt like we were racing toward some inevitable singularity where life itself would be programmable. Are we?
www.connectedideasproject.com
March 4, 2025 at 2:58 PM
In the world of dual-use and dual-hype, the #AI and #biotech debate reigns supreme. But a recent report by Epoch AI shows that the progress is moderating and evolving. I think we're maturing into actual use-cases that are demonstrating impact.
www.connectedideasproject.com/p/ep-26-the-...
www.connectedideasproject.com/p/ep-26-the-...
Sci-Fi Friday: In a world where life is engineered and perfection is manufactured, what does it mean to be human?
www.connectedideasproject.com/p/ssi-part-5...
www.connectedideasproject.com/p/ssi-part-5...
SSI Part 5: The Architects of Flesh
In a world where life is engineered and perfection is manufactured, what does it mean to be human?
www.connectedideasproject.com
February 21, 2025 at 5:40 PM
Sci-Fi Friday: In a world where life is engineered and perfection is manufactured, what does it mean to be human?
www.connectedideasproject.com/p/ssi-part-5...
www.connectedideasproject.com/p/ssi-part-5...
The Nobel Turing challenge used to sound like sci-fi. Today it sounds inevitable.
www.connectedideasproject.com/p/ep-22-nobe...
www.connectedideasproject.com/p/ep-22-nobe...
Ep 22 - The Nobel Turing Challenge: A New Dawn for Discovery
How AI Could Transform Science and Redefine Human Potential
www.connectedideasproject.com
February 4, 2025 at 12:37 PM
The Nobel Turing challenge used to sound like sci-fi. Today it sounds inevitable.
www.connectedideasproject.com/p/ep-22-nobe...
www.connectedideasproject.com/p/ep-22-nobe...
Sci-Fi Friday: In a world where wars are fought with algorithms and nations bow to machines, the battle for control is silent—but relentless.
www.connectedideasproject.com/p/ssi-part-1...
www.connectedideasproject.com/p/ssi-part-1...
SSI Part 1: The Silent War
In a world where wars are fought with algorithms and nations bow to machines, the battle for control is silent—but relentless.
www.connectedideasproject.com
January 24, 2025 at 7:11 PM
Sci-Fi Friday: In a world where wars are fought with algorithms and nations bow to machines, the battle for control is silent—but relentless.
www.connectedideasproject.com/p/ssi-part-1...
www.connectedideasproject.com/p/ssi-part-1...
We are a little over four months post-launch of The Connected Ideas Project, and the community is amazing. If you're interested in the co-evolution of tech and policy, and how it's impacting our lives, come join us!
www.connectedideasproject.com
www.connectedideasproject.com
The Connected Ideas Project | Alexander Titus | Substack
Exploring how tech, policy, people, and ideas are connected. A special love for AI and biotechnology, but a lot of thinking about how emerging technologies like fusion, AI, quantum, and more are impac...
www.connectedideasproject.com
January 24, 2025 at 7:11 PM
We are a little over four months post-launch of The Connected Ideas Project, and the community is amazing. If you're interested in the co-evolution of tech and policy, and how it's impacting our lives, come join us!
www.connectedideasproject.com
www.connectedideasproject.com