Alberto León-Halcón
@albertolh.bsky.social
PhD Student at Department of Genetics in University of Seville. I am studying RNA metabolism in the context of topoisomerase activity at Silvia Jimeno's lab, in CABIMER. Now more focused on epitranscriptomic landscape.
Our new paper has just been published at Cell Reports!!!🎊: "DNA topoisomerase II promotes N6-adenosine mRNA methylation" www.cell.com/cell-reports...
DNA topoisomerase II promotes N6-adenosine mRNA methylation
Megías-Fernández et al. reveal that TOP2 facilitates RNA polymerase II elongation
while promoting co-transcriptional m6A deposition through METTL3 recruitment. This
dual role ensures basal transcripti...
www.cell.com
November 3, 2025 at 3:12 PM
Our new paper has just been published at Cell Reports!!!🎊: "DNA topoisomerase II promotes N6-adenosine mRNA methylation" www.cell.com/cell-reports...