Alan Parker
@alanlparker.bsky.social
Turning viruses into cancer medicines. Head of Solid Cancers & Professor of Translational Virotherapies @cardiffuni. FLSW. Awesome group: @virustinkerer. Dad to 2 cricket 🏏nuts. #LFC #ProEU. #Athiest. #Humanist.
📢📢FINAL CALL!! Closes tomorrow (Mon 20th Oct)
Want a cool, blue skies project, integrating machine learning with virology to develop the medicines 💊of the future?
Want to join a supportive team with an incredible culture?
Apply now! 🧬🔬🧪🦠👨🔬👩🔬
www.findaphd.com/phds/project...
Want a cool, blue skies project, integrating machine learning with virology to develop the medicines 💊of the future?
Want to join a supportive team with an incredible culture?
Apply now! 🧬🔬🧪🦠👨🔬👩🔬
www.findaphd.com/phds/project...
October 19, 2025 at 11:20 AM
📢📢FINAL CALL!! Closes tomorrow (Mon 20th Oct)
Want a cool, blue skies project, integrating machine learning with virology to develop the medicines 💊of the future?
Want to join a supportive team with an incredible culture?
Apply now! 🧬🔬🧪🦠👨🔬👩🔬
www.findaphd.com/phds/project...
Want a cool, blue skies project, integrating machine learning with virology to develop the medicines 💊of the future?
Want to join a supportive team with an incredible culture?
Apply now! 🧬🔬🧪🦠👨🔬👩🔬
www.findaphd.com/phds/project...
Great to have this out as a preprint - a fantastic collaborative effort led ably by the dream team of Rosie and Kasim....have a look, the structures are amazing!
Identification of a novel structural motif and overexpression of key transcripts elucidated in Adenovirus 10 https://www.biorxiv.org/content/10.1101/2025.09.20.677498v1
September 21, 2025 at 10:13 AM
Great to have this out as a preprint - a fantastic collaborative effort led ably by the dream team of Rosie and Kasim....have a look, the structures are amazing!
Great to have this out as a preprint - a fantastic collaborative effort led ably by the dream team of Rosie and Kasim....have a look, the structures are amazing!
Identification of a novel structural motif and overexpression of key transcripts elucidated in Adenovirus 10 https://www.biorxiv.org/content/10.1101/2025.09.20.677498v1
September 21, 2025 at 10:12 AM
Great to have this out as a preprint - a fantastic collaborative effort led ably by the dream team of Rosie and Kasim....have a look, the structures are amazing!
Potential @gw4biomeddtp.bsky.social 4 year PhD project for Oct 2026 start adopting machine learning to develop precision virotherapies - co-supervisors Yukun Lai, @mariekedoesscience.bsky.social, Kerry Wadey & Julian Fischer. Come, make some smart viruses with us!
gw4biomed.ac.uk/developing-p...
gw4biomed.ac.uk/developing-p...
Developing precision guided, viral based therapies using machine learning approaches - GW4 BioMed MRC DTP
Project Code MRCIIAR26Ca Parker Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary The Viral ImmunoTherapies and Advanced The...
gw4biomed.ac.uk
September 1, 2025 at 2:31 PM
Potential @gw4biomeddtp.bsky.social 4 year PhD project for Oct 2026 start adopting machine learning to develop precision virotherapies - co-supervisors Yukun Lai, @mariekedoesscience.bsky.social, Kerry Wadey & Julian Fischer. Come, make some smart viruses with us!
gw4biomed.ac.uk/developing-p...
gw4biomed.ac.uk/developing-p...
Reposted by Alan Parker
Make sure you don't miss our next #Advancedtherapies MDRG on Friday.
Hear from Dr Michael Chapman -'CAR-T therapy in haematological malignancy' and Professor Andrew Sewell 'How T-Cells clear cancer'
Virtual option available
#Research
@alanlparker.bsky.social @lifesciencescymru.bsky.social
Hear from Dr Michael Chapman -'CAR-T therapy in haematological malignancy' and Professor Andrew Sewell 'How T-Cells clear cancer'
Virtual option available
#Research
@alanlparker.bsky.social @lifesciencescymru.bsky.social
September 1, 2025 at 8:42 AM
Make sure you don't miss our next #Advancedtherapies MDRG on Friday.
Hear from Dr Michael Chapman -'CAR-T therapy in haematological malignancy' and Professor Andrew Sewell 'How T-Cells clear cancer'
Virtual option available
#Research
@alanlparker.bsky.social @lifesciencescymru.bsky.social
Hear from Dr Michael Chapman -'CAR-T therapy in haematological malignancy' and Professor Andrew Sewell 'How T-Cells clear cancer'
Virtual option available
#Research
@alanlparker.bsky.social @lifesciencescymru.bsky.social
Reposted by Alan Parker
Very excited our paper describing the development of a precision Virotherapy directly delivering bispecific molecules to tumour cells is in it's final polished form!
www.cell.com/molecular-th...
www.cell.com/molecular-th...
An αvβ6-specific virotherapy expressing bispecific immune cell activators induces immune cell activation to mediate tumor cell death
Virotherapies can deliver anti-cancer therapeutics directly to tumors. Bayliss and
colleagues develop a precision virotherapy expressing bispecific immunotherapies from
tumor cells resulting in immune...
www.cell.com
July 28, 2025 at 8:26 PM
Very excited our paper describing the development of a precision Virotherapy directly delivering bispecific molecules to tumour cells is in it's final polished form!
www.cell.com/molecular-th...
www.cell.com/molecular-th...
Reposted by Alan Parker
Am Sdeddfod wych!! Diolch o galon i bawb ddaeth i'n gweld ni ym mhabell @prifysgolcdydd.bsky.social, i ddysgu mwy am ein gwaith yn Uned firoleg gymhwysol Cymru Wales Applied Virology Unit (WAVU). Braf odd cal gweld y "firysau" oddachi wedi ei greu o gwmpas y maes!
August 8, 2025 at 3:00 PM
Am Sdeddfod wych!! Diolch o galon i bawb ddaeth i'n gweld ni ym mhabell @prifysgolcdydd.bsky.social, i ddysgu mwy am ein gwaith yn Uned firoleg gymhwysol Cymru Wales Applied Virology Unit (WAVU). Braf odd cal gweld y "firysau" oddachi wedi ei greu o gwmpas y maes!
If you’re visiting #Eisteddfodd today, do speak to the awesome @lunedbadder.bsky.social representing @cardiffunilib.bsky.social, the VITAL lab & HCRW Wales Applied Virology Unit (WAVU), explaining how we develop “#SmartViruses” to treat #Cancer. You can even make a designer virus of your own!
August 6, 2025 at 9:15 AM
If you’re visiting #Eisteddfodd today, do speak to the awesome @lunedbadder.bsky.social representing @cardiffunilib.bsky.social, the VITAL lab & HCRW Wales Applied Virology Unit (WAVU), explaining how we develop “#SmartViruses” to treat #Cancer. You can even make a designer virus of your own!
Congratulations to @gw4biomeddtp.bsky.social @atwales.bsky.social funded PhD student Rosie Mundy, presenting her groundbreaking structural and transcriptomic analysis of Ad10 today at the International Adenovirus Meeting at @cardiffunilib.bsky.social centre for student life.
July 8, 2025 at 2:02 PM
Congratulations to @gw4biomeddtp.bsky.social @atwales.bsky.social funded PhD student Rosie Mundy, presenting her groundbreaking structural and transcriptomic analysis of Ad10 today at the International Adenovirus Meeting at @cardiffunilib.bsky.social centre for student life.
Big moment for the youngest, collecting his first cap for @glamcricket.bsky.social U13 yesterday. Two terrific matches against a strong Gloucestershire U13 but showed their class securing back to back T20 wins. Exciting times ahead! 👏👏🏏 💥
May 26, 2025 at 1:09 PM
Big moment for the youngest, collecting his first cap for @glamcricket.bsky.social U13 yesterday. Two terrific matches against a strong Gloucestershire U13 but showed their class securing back to back T20 wins. Exciting times ahead! 👏👏🏏 💥
Thanks for inviting me to be an honorary @pharmacycu.bsky.social member for and to talk "how to train your virus" at the ever wonderful @pintofscience.uk event at Tiny Rebel, Cardiff! A great evening talking about crossing the "Valley of Death" and into the clinic with our "smart viruses".
May 21, 2025 at 6:48 PM
Thanks for inviting me to be an honorary @pharmacycu.bsky.social member for and to talk "how to train your virus" at the ever wonderful @pintofscience.uk event at Tiny Rebel, Cardiff! A great evening talking about crossing the "Valley of Death" and into the clinic with our "smart viruses".
Looking forward to my favourite #PublicEngagement event @pintofscience! I'll talk "how to train your virus" at @TinyRebelCdff on 20/05, discussing how we turned a disease causing "nasty" into a clinical stage anticancer medicine. Grab a pint, pop along! pintofscience.co.uk/event/from-b...
May 5, 2025 at 7:41 AM
Looking forward to my favourite #PublicEngagement event @pintofscience! I'll talk "how to train your virus" at @TinyRebelCdff on 20/05, discussing how we turned a disease causing "nasty" into a clinical stage anticancer medicine. Grab a pint, pop along! pintofscience.co.uk/event/from-b...
Thrilled and honoured to be announced as a Health and Care Research Wales Senior Research Leader. Looking forward to contributing towards accelerating translational research, shaping policy and mentoring the next generation of researchers in Wales.
healthandcareresearchwales.org/about/news/h...
healthandcareresearchwales.org/about/news/h...
Health and Care Research Wales announces appointments of Senior Research Leaders
healthandcareresearchwales.org
May 2, 2025 at 12:53 PM
Thrilled and honoured to be announced as a Health and Care Research Wales Senior Research Leader. Looking forward to contributing towards accelerating translational research, shaping policy and mentoring the next generation of researchers in Wales.
healthandcareresearchwales.org/about/news/h...
healthandcareresearchwales.org/about/news/h...
Join our new Wales Applied Virology Unit as a Lecturer in Infectious Disease Epidemiology / Behavioural Science!
See the advert here:
krb-sjobs.brassring.com/TGnewUI/Search…
And contact WAVU co-director David Gillespie for informal enquiries.
#NewPI #Lecturer #GroupLeader #Job #Opportunity
See the advert here:
krb-sjobs.brassring.com/TGnewUI/Search…
And contact WAVU co-director David Gillespie for informal enquiries.
#NewPI #Lecturer #GroupLeader #Job #Opportunity
April 16, 2025 at 6:23 AM
Join our new Wales Applied Virology Unit as a Lecturer in Infectious Disease Epidemiology / Behavioural Science!
See the advert here:
krb-sjobs.brassring.com/TGnewUI/Search…
And contact WAVU co-director David Gillespie for informal enquiries.
#NewPI #Lecturer #GroupLeader #Job #Opportunity
See the advert here:
krb-sjobs.brassring.com/TGnewUI/Search…
And contact WAVU co-director David Gillespie for informal enquiries.
#NewPI #Lecturer #GroupLeader #Job #Opportunity
Well, this is exciting, and has been a long time in the making. Many thanks to the many, many exceptional authors for their expert contributions. Would make a lovely Easter gift....(who needs chocolate eggs, right...?)
April 9, 2025 at 2:21 PM
Well, this is exciting, and has been a long time in the making. Many thanks to the many, many exceptional authors for their expert contributions. Would make a lovely Easter gift....(who needs chocolate eggs, right...?)
Great to be over in London today UCL institute for child heath for what promises to be an awesome day of #AdvancedTherapies #UCL2025AdvTx . Thanks @atwales.bsky.social for funding my trip over! Looking forward to a great day!
April 9, 2025 at 9:01 AM
Great to be over in London today UCL institute for child heath for what promises to be an awesome day of #AdvancedTherapies #UCL2025AdvTx . Thanks @atwales.bsky.social for funding my trip over! Looking forward to a great day!
Reposted by Alan Parker
April 9, 2025 at 8:40 AM
Huge congrats 🥂 to our latest virus tinkerer fledgling Dr Adam Naskretski MD! What a journey it’s been but my goodness you have deserved it! Many thanks to fabulous viva panel Fiona Errington-Mais, Mererid Evans and @alextonks.bsky.social for chairing! 👏🎉👍🏻🥳🦠
March 14, 2025 at 10:58 AM
Huge congrats 🥂 to our latest virus tinkerer fledgling Dr Adam Naskretski MD! What a journey it’s been but my goodness you have deserved it! Many thanks to fabulous viva panel Fiona Errington-Mais, Mererid Evans and @alextonks.bsky.social for chairing! 👏🎉👍🏻🥳🦠
Reposted by Alan Parker
Scientists found that the AstraZeneca COVID-19 vaccine can infect endothelial cells but doesn’t activate them, suggesting it’s not a direct cause of VITT.
The vaccine’s hexon protein binds PF4, supporting a role in triggering the immune response.
www.biorxiv.org/content/10.1...
The vaccine’s hexon protein binds PF4, supporting a role in triggering the immune response.
www.biorxiv.org/content/10.1...
Investigating endothelial cell transduction and hexon:PF4 binding of ChAdOx1 in the context of VITT
Background: Vaccines against SARS-CoV2 have been essential in controlling COVID-19 related mortality and have saved millions of lives. Adenoviral (Ad) based vaccines have played an integral part in th...
www.biorxiv.org
March 12, 2025 at 1:45 PM
Scientists found that the AstraZeneca COVID-19 vaccine can infect endothelial cells but doesn’t activate them, suggesting it’s not a direct cause of VITT.
The vaccine’s hexon protein binds PF4, supporting a role in triggering the immune response.
www.biorxiv.org/content/10.1...
The vaccine’s hexon protein binds PF4, supporting a role in triggering the immune response.
www.biorxiv.org/content/10.1...
Preprint klaxon: Investigating endothelial cell transduction and hexon:PF4 binding of ChAdOx1 in the context of VITT.
Providing evidence of direct PF4 binding to purified hexon protein, & efficient, CAR independent transduction (but not activation) of ECs by ChAdOx1
www.biorxiv.org/content/10.1...
Providing evidence of direct PF4 binding to purified hexon protein, & efficient, CAR independent transduction (but not activation) of ECs by ChAdOx1
www.biorxiv.org/content/10.1...
Investigating endothelial cell transduction and hexon:PF4 binding of ChAdOx1 in the context of VITT
Background: Vaccines against SARS-CoV2 have been essential in controlling COVID-19 related mortality and have saved millions of lives. Adenoviral (Ad) based vaccines have played an integral part in th...
www.biorxiv.org
March 11, 2025 at 2:55 PM
Preprint klaxon: Investigating endothelial cell transduction and hexon:PF4 binding of ChAdOx1 in the context of VITT.
Providing evidence of direct PF4 binding to purified hexon protein, & efficient, CAR independent transduction (but not activation) of ECs by ChAdOx1
www.biorxiv.org/content/10.1...
Providing evidence of direct PF4 binding to purified hexon protein, & efficient, CAR independent transduction (but not activation) of ECs by ChAdOx1
www.biorxiv.org/content/10.1...
Reposted by Alan Parker
Investigating endothelial cell transduction and hexon:PF4 binding of ChAdOx1 in the context of VITT https://www.biorxiv.org/content/10.1101/2025.03.09.642192v1
March 11, 2025 at 10:18 AM
Investigating endothelial cell transduction and hexon:PF4 binding of ChAdOx1 in the context of VITT https://www.biorxiv.org/content/10.1101/2025.03.09.642192v1
Reposted by Alan Parker
Investigating endothelial cell transduction and hexon:PF4 binding of ChAdOx1 in the context of VITT https://www.biorxiv.org/content/10.1101/2025.03.09.642192v1
March 11, 2025 at 10:18 AM
Investigating endothelial cell transduction and hexon:PF4 binding of ChAdOx1 in the context of VITT https://www.biorxiv.org/content/10.1101/2025.03.09.642192v1
Our virus tinkerers are out today at the Sbarc/Spark building for “be a scientist” day! If you’re looking for an interactive event to inspire the kids this half term, why not come down and build a virus - and learn all about how we are making “smart viruses” to treat disease! 🦠
February 25, 2025 at 10:31 AM
Our virus tinkerers are out today at the Sbarc/Spark building for “be a scientist” day! If you’re looking for an interactive event to inspire the kids this half term, why not come down and build a virus - and learn all about how we are making “smart viruses” to treat disease! 🦠
Reposted by Alan Parker
If you're looking for a lectureship in virology/viral immunology then good news, we have a position available!
Want to hear a great #Virology opportunity? We have an amazing opportunity for a new PI/#Lecturer/group leader in virology/viral immunology as part of a new @researchwales.bsky.social Virology unit headed by myself, @richstanton.bsky.social @davidgillespie.bsky.social
tinyurl.com/2c2jkerd
tinyurl.com/2c2jkerd
Job Search | Cardiff University
Search for Internet job results.
krb-sjobs.brassring.com
February 19, 2025 at 7:12 PM
If you're looking for a lectureship in virology/viral immunology then good news, we have a position available!