Ainoa Guinart
ainoaguinart.bsky.social
Ainoa Guinart
@ainoaguinart.bsky.social
PhD candidate @FeringaLab (Groningen, Netherlands)
Biomolecular machines 🧪⚡️ in soft materials 👩🏻‍🔬. I also love cats 🐱 and microscopes 🔬
👩‍🔬Our new paper is out in Chem! @feringalab.bsky.social We unveil how light-driven rotary motors behave in lipid membranes—and why system-specific characterization is crucial.

Structure & polarity shape membrane interaction and function. Read (or see comments): doi.org/10.1016/j.ch...
Redirecting
doi.org
May 7, 2025 at 8:36 AM
Do you want to see how attaching a light-driven 💡molecular motor 💡 can enhance the 🧫cellular uptake 🧫 of a therapeutic peptide 🏥?

Celebrating woman in science with our latest publication with the VicentPTlab! 👩‍⚕️👩‍⚕️👩‍⚕️

@feringalab.bsky.social

pubs.rsc.org/en/content/a...
A light-driven molecular motor-polypeptide conjugate supports controlled cell uptake
While light-driven molecular motors (MMs) hold immense potential to control cell function, low biocompatibility and solubility have hampered their implementation. We developed a novel polypeptide-conj...
pubs.rsc.org
February 13, 2025 at 11:29 AM
🚨Motorized lipids🚨

💡 We've created the first molecular-motor-conjugated phospholipid system, enabling tunable membrane properties and oxidation-driven release in giant vesicles.💡🧬

@feringalab.bsky.social & Schwille Lab in ACS_Langmuir

pubs.acs.org/doi/full/10....
Photoswitchable Molecular Motor Phospholipid: Synthesis, Characterization, and Integration into Lipid Vesicles
Lipid membranes are essential for cellular function, acting as barriers and platforms for major cellular and biochemical activities. The integration of photoisomerizable units into lipid structures al...
pubs.acs.org
February 5, 2025 at 10:24 AM
Check out our latest publication where we elicit a light-triggered ⚡️ cascade response in a synthetic cell 🔬using polymersomes and molecular motors👩🏻‍🔬!

Thanks always to the @feringalab.bsky.social and our amazing collaborators from @unibas.ch

advanced.onlinelibrary.wiley.com/doi/10.1002/...
Photoreceptor‐Like Signal Transduction Between Polymer‐Based Protocells (Adv. Mater. 3/2025)
Protocell Communication and Signaling Polymer-based protocells equipped with artificial organelles mimic the transduction of information in retinal photoreceptors. Cellular communication involving sp...
advanced.onlinelibrary.wiley.com
January 26, 2025 at 3:25 PM
Check out this amazing ScienceSlam about our recent project at the FeringaLab. doi.org/10.1002/adma...

We explore how synthetic molecular machines interact with lipid membranes, triggering crazy shape transformations

Great example how research is not only done in the lab!

youtu.be/S7WKGf_idTE?...
Science Slam of the Munich Clusters of Excellence: Controlling cellular membranes with tiny motors
YouTube video by ORIGINS Cluster
youtu.be
November 18, 2024 at 8:55 PM