Ahamed PK
@ahamedpk.bsky.social
PhD candidate, Erika Gyengesi Lab, WSU
IISc graduate, 2024
Cholinergic system | Neuroinflammation | Neuroscience
IISc graduate, 2024
Cholinergic system | Neuroinflammation | Neuroscience
Check out this interesting study that identifies a potential rescue mechanism for APOE4 induced defects in neuronal proteostasis and synaptic plasticity.
www.life-science-alliance.org/content/9/2/...
#Alzheimers #APOE4
www.life-science-alliance.org/content/9/2/...
#Alzheimers #APOE4
Group 1 mGluR stimulation rescues APOE4-mediated translation defects in neurons
The E4 isoform of apolipoprotein (APOE4) is the most recognized risk factor for Alzheimer’s disease, implicated in early neurodegeneration and impaired synaptic plasticity. In neurons, exposure to APO...
www.life-science-alliance.org
November 12, 2025 at 12:50 PM
Check out this interesting study that identifies a potential rescue mechanism for APOE4 induced defects in neuronal proteostasis and synaptic plasticity.
www.life-science-alliance.org/content/9/2/...
#Alzheimers #APOE4
www.life-science-alliance.org/content/9/2/...
#Alzheimers #APOE4
Reposted by Ahamed PK
Association of Bassoon (BSN) Gene Mutations with Gait and Motor Impairments in Parkinson's Disease https://www.medrxiv.org/content/10.1101/2025.08.10.25333397v1
August 13, 2025 at 12:26 AM
Association of Bassoon (BSN) Gene Mutations with Gait and Motor Impairments in Parkinson's Disease https://www.medrxiv.org/content/10.1101/2025.08.10.25333397v1
I invite you all to read our recent review article on the presynaptic protein Bassoon. The article addresses a crucial topic, the involvement of Bassoon in neurological diseases and the lack of mechanistic information thereof.
#bassoon #BSN #Disease
onlinelibrary.wiley.com/doi/10.1111/...
#bassoon #BSN #Disease
onlinelibrary.wiley.com/doi/10.1111/...
Bassoon, Presynaptic Scaffolding Protein: Narrative Review in Health and Disease
Presynaptic Scaffolding Protein: Bassoon. The graphical abstract visually summarizes the role of Bassoon (BSN), a presynaptic scaffolding protein, in both normal physiological functions and disease s....
onlinelibrary.wiley.com
March 28, 2025 at 3:01 AM
I invite you all to read our recent review article on the presynaptic protein Bassoon. The article addresses a crucial topic, the involvement of Bassoon in neurological diseases and the lack of mechanistic information thereof.
#bassoon #BSN #Disease
onlinelibrary.wiley.com/doi/10.1111/...
#bassoon #BSN #Disease
onlinelibrary.wiley.com/doi/10.1111/...