Adrija Navarro-Traxler
@adrijanavarro.bsky.social
Postdoc at DFCI | HMS alumna | Cancer signaling metabolism and immunology | Princeton ‘15 | Musician | Sailor | Cat mom
Reposted by Adrija Navarro-Traxler
Congratulations to the wonderfully-talented @adrijanavarro.bsky.social on her #JBC paper out today! We took a dive into the wonderful world of glycobiology, linking it to AKT and oncogene signaling in cancer. Brought to you by Toker Lab productions. @asbmbjournals.bsky.social
The glycosyltransferase ALG3 is an AKT substrate that regulates protein N-glycosylation
AKT phosphorylates the glycosyltransferase ALG3. The PI3K/AKT signaling pathway is
frequently dysregulated in cancer and controls key cellular processes such as survival,
proliferation, metabolism, an...
www.jbc.org
September 8, 2025 at 11:25 PM
Congratulations to the wonderfully-talented @adrijanavarro.bsky.social on her #JBC paper out today! We took a dive into the wonderful world of glycobiology, linking it to AKT and oncogene signaling in cancer. Brought to you by Toker Lab productions. @asbmbjournals.bsky.social
🚨 New preprint out!
“ALG3 is an AKT substrate that links PI3K signaling to N-glycosylation”
👉 doi.org/10.1101/2025.04.01.646556
This is my big PhD paper—years in the making. So proud to finally share.
Huge thanks to Alex Toker, Evan Lien, Laura Ghisolfi, and the Toker lab for all the support. 💛
“ALG3 is an AKT substrate that links PI3K signaling to N-glycosylation”
👉 doi.org/10.1101/2025.04.01.646556
This is my big PhD paper—years in the making. So proud to finally share.
Huge thanks to Alex Toker, Evan Lien, Laura Ghisolfi, and the Toker lab for all the support. 💛
The glycosyltransferase ALG3 is an AKT substrate that regulates protein N-glycosylation
The PI3K/AKT signaling pathway is frequently dysregulated in cancer and controls key cellular processes such as survival, proliferation, metabolism and growth. Protein glycosylation is essential for p...
doi.org
April 3, 2025 at 8:24 PM
🚨 New preprint out!
“ALG3 is an AKT substrate that links PI3K signaling to N-glycosylation”
👉 doi.org/10.1101/2025.04.01.646556
This is my big PhD paper—years in the making. So proud to finally share.
Huge thanks to Alex Toker, Evan Lien, Laura Ghisolfi, and the Toker lab for all the support. 💛
“ALG3 is an AKT substrate that links PI3K signaling to N-glycosylation”
👉 doi.org/10.1101/2025.04.01.646556
This is my big PhD paper—years in the making. So proud to finally share.
Huge thanks to Alex Toker, Evan Lien, Laura Ghisolfi, and the Toker lab for all the support. 💛
Reposted by Adrija Navarro-Traxler
Ludwig @harvard.edu’s @alextoker.bsky.social discusses his work, what drew him into a life of science and what compels him to contribute to cancer research.
youtu.be/IIG5VD8EHB8
#CancerResearch #CancerChat #ImmunoSky
youtu.be/IIG5VD8EHB8
#CancerResearch #CancerChat #ImmunoSky
Alex Toker, Ludwig Harvard
YouTube video by Ludwig Cancer Research
youtu.be
January 7, 2025 at 2:35 PM
Ludwig @harvard.edu’s @alextoker.bsky.social discusses his work, what drew him into a life of science and what compels him to contribute to cancer research.
youtu.be/IIG5VD8EHB8
#CancerResearch #CancerChat #ImmunoSky
youtu.be/IIG5VD8EHB8
#CancerResearch #CancerChat #ImmunoSky
Reposted by Adrija Navarro-Traxler
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
November 25, 2024 at 12:38 PM
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
Reposted by Adrija Navarro-Traxler
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
November 23, 2024 at 3:50 PM
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
Reposted by Adrija Navarro-Traxler
Published a few weeks ago in Cancer Research, we show benefit of targeting HMCR with pitavastatin in combo with AKT inhibitors in TNBC. Many amazing people contributed, led by the magnificently talented @alissandra-hillis.bsky.social! Looking to initiate new clinical trials based on this combo. 🧪
Targeting Cholesterol Biosynthesis with Statins Synergizes with AKT Inhibitors in Triple-Negative Breast Cancer
Two FDA-approved compounds, AKT inhibitors and pitavastatin, synergize to induce cell death in triple-negative breast cancer, motivating evaluation of the efficacy of this combination in clinical tria...
aacrjournals.org
November 20, 2024 at 12:09 PM
Published a few weeks ago in Cancer Research, we show benefit of targeting HMCR with pitavastatin in combo with AKT inhibitors in TNBC. Many amazing people contributed, led by the magnificently talented @alissandra-hillis.bsky.social! Looking to initiate new clinical trials based on this combo. 🧪
It was such a pleasure to organize for Harry the Healer to come to our lab yesterday! Not only did he have the cutest badge, but his calming and healing nature were very helpful in rejuvenating spirits for all our hard working scientists!
November 20, 2024 at 8:50 PM
It was such a pleasure to organize for Harry the Healer to come to our lab yesterday! Not only did he have the cutest badge, but his calming and healing nature were very helpful in rejuvenating spirits for all our hard working scientists!