Achim Lother
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achimlother.bsky.social
Achim Lother
@achimlother.bsky.social
76 followers 130 following 21 posts
Clinician Scientist @imit-freiburg.bsky.social, basic to translational research in intensive care, heart failure, pharmacology, epigenetics, and mineralocorticoid receptor signaling #Freiburg http://cardiovascularpharmacology.org
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achimlother.bsky.social
Looking forward to an exciting 2025 meeting of the European Section of the Aldosterone Council - at beautiful Rome!
@aldolabz.bsky.social @boulkrounshee.bsky.social
October 17, 2025 at 9:29 AM
Reposted by Achim Lother
imit-freiburg.bsky.social
Save the date!
Liebe Kolleginnen und Kollegen,
ganz herzlich laden wir Sie zur Veranstaltung „Neues aus der Intensivmedizin“ (NIM 2026) am Freitag, 16. Januar 2026 ab 18 Uhr in die Bibliothek der Frauenklinik ein.

@afluegler.bsky.social @tobi-wengenmayer.bsky.social
October 16, 2025 at 11:53 AM
Reposted by Achim Lother
xkcd.com
Question Mark

xkcd.com/3143/
Comic. PERSON 1: That movie was so good. Maybe even the greatest movie of all time question mark? PERSON 2: Yeah comma, but you said that about italics *Charlie’s Angels Colon: Full Throttle* period. Paragraph break. I question your judgement period. [caption] When people say “question mark” out loud as a rhetorical device, it always makes me want to say my other punctuation and formatting too.
September 18, 2025 at 8:14 PM
achimlother.bsky.social
Happy to share our recent paper, led by Elias Erny:
👉 Endothelial cell stop proliferating in heart failure despite VEGF ⏫
👉 transcription factors TCF19 and ATAD2 control endothelial cell proliferation and angiogenesis
rdcu.be/eGYpJ
Big thanks to all co-authors for the great collaboration #SFB1425
September 18, 2025 at 6:52 AM
achimlother.bsky.social
This!
ec.europa.eu European Commission @ec.europa.eu · Aug 5
Double the discovery, double the momentum 🚀

Europe doubles down on research competitiveness with a major boost to #HorizonEurope:

€95.5 billion foreseen for 2021-2027
💰💰💰💰💰💰💰💰💰

€175 billion proposed for 2028-2034
💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰
August 5, 2025 at 8:24 PM
achimlother.bsky.social
Our latest preprint from the lab is now online:
- single nucleus RNAseq comparison of aldosterone/salt vs high fat diet/L-NAME induced HFpEF
- fibroblast specific MR knock-out
dx.doi.org/10.21203/rs....
We are looking forward to your thoughts and comments!
July 14, 2025 at 12:03 PM
achimlother.bsky.social
Enjoying excellent presentations and meeting with colleagues and friends at International Aldosterone Conference at San Francisco. Can't wait to see you again in Rome later this year!
admire-network.org/2025/06/02/a... @endocrinesociety.bsky.social
Abstract submission ESAC 2025 in Rome – ADMIRE network
admire-network.org
July 11, 2025 at 6:55 PM
Reposted by Achim Lother
criticalcarereviews.com
Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest

CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch
May 31, 2025 at 10:21 AM
Reposted by Achim Lother
imit-freiburg.bsky.social
Happy to share our recent review article on Extracorporeal Cardiopulmonary Resuscitation in refractory cardiac arrest published in @lancetrespirmed.bsky.social covering all aspects and recent evidence of #ECPR for in-hospital and out-of-hospital cardiac arrest #OHCA #IHCA

Open Access bit.ly/3HjVSsV
Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest
When conventional cardiopulmonary resuscitation (CCPR) cannot restore spontaneous circulation, the initiation of venoarterial extracorporeal membrane oxygenation during refractory cardiac arrest—known...
bit.ly
May 31, 2025 at 7:16 AM
achimlother.bsky.social
Abstract submission for the #ESAC2025 European Aldosterone Conference in Rome will open from June 1st to July 15th. Looking forward to your submissions!
May 29, 2025 at 12:43 PM
achimlother.bsky.social
Congratulations! @cibss.bsky.social @uni-freiburg.de
dfg.de Deutsche Forschungsgemeinschaft @dfg.de · May 22
Die #Exzellenzcluster stehen fest: Heute hat die Exzellenzkommission 70 Projekte zur Förderung ausgewählt. 45 Cluster werden fortgesetzt, 25 neu eingerichtet. Die Förderung beginnt ab 1. Jan. 2026 für 7 Jahre, die Fördersumme beträgt insg. 539 Mio. €/Jahr. Die Liste: www.dfg.de/resource/blo... 1/3
Deutschlandkarte der Verteilung der Exzellenzcluster auf Bundesländer und Universitäten.
May 22, 2025 at 3:18 PM
Reposted by Achim Lother
haoyin.bsky.social
#SpatialTranscriptomics 👤 #Cardiomyopathy #HeartFailure
GeoMx
Cardiomyocyte #EndothelialCell Fibroblast segmented
44👤🫀 #TissueMicroArray

#MyocyteDisarray HCMpEF➡️⏬ribosome
#CardicFibrosis➡️⏫ACKR1+PLVAP+CCL14+ endothelium
UCHL1 PFKFB2 for HF progression

#EHJ 2025
academic.oup.com/eurheartj/ad...
May 20, 2025 at 11:44 AM
achimlother.bsky.social
#Aldosterone alters cardiomyocyte states and changes cell-cell interactions, finally leading to atrial myopathy and atrial fibrillation.
www.ahajournals.org/doi/10.1161/... #afib Shout out to David Meral de.linkedin.com/in/david-mer...
May 15, 2025 at 6:11 AM
Reposted by Achim Lother
imit-freiburg.bsky.social
New insights from the German VA-ECMO registry: Clinical use and predictors of outcome in venoarterial extracorporeal membrane oxygenation.
link.springer.com/article/10.1...
@tobi-wengenmayer.bsky.social
Clinical use and predictors of outcome in venoarterial extracorporeal membrane (VA ECMO): insights from VERGE (VA ECMO Registry of Germany) - Clinical Research in Cardiology
The VA ECMO Registry of Germany (VERGE, http://va-ecmo-register.de/ ) is a prospective, multicenter, investigator-driven registry of Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) all-come...
link.springer.com
May 15, 2025 at 6:02 AM
Reposted by Achim Lother
haoyin.bsky.social
#Mechanobiology #RigiditySensing

Cellular mechanosignaling for sensing and transducing matrix rigidity

#YAP/TAZ
#Piezo
Mechanometabolism
Substrate with tunable stiffness

Cynthia Reinhart-King lab #CurrOpinCellBiol 2023
www.sciencedirect.com/science/arti...
May 11, 2025 at 2:15 PM
Reposted by Achim Lother
imit-freiburg.bsky.social
Meta analysis suggests benefit of prone positioning for patients on #ECMO - RCT needed for definite answers. link.springer.com/article/10.1... @tobi-wengenmayer.bsky.social
Prone positioning during veno-venous extracorporeal membrane oxygenation: a systematic review and meta-analysis - Intensive Care Medicine
Purpose The evidence supporting the benefit on clinical outcomes of prone positioning during veno-venous extracorporeal membrane oxygenation (V-V ECMO) for acute hypoxemic respiratory failure remains ...
link.springer.com
May 12, 2025 at 7:33 AM
Reposted by Achim Lother
imit-freiburg.bsky.social
It takes excellent research to move intensive care medicine forward: Happy to see exciting data, lively discussions, and many new project ideas at IMIT Science Day 2025…
May 12, 2025 at 7:37 AM
Reposted by Achim Lother
natrevdiseaseprimers.nature.com
Our NEW Primer on Thoracic aortic aneurysm is live today! By Berger, Dumfarth, Kreibich, Minatoya, Ziganshin & Czerny. Check it out here:
Thoracic aortic aneurysm - Nature Reviews Disease Primers
Thoracic aortic aneurysm (TAA) is characterized by dilation of the aorta. In this Primer, Berger et al. review the epidemiology, pathophysiological mechanisms, diagnosis and management of TAA, and provide insights into its effect on quality of life and suggestions for areas of future research.
www.nature.com
May 8, 2025 at 11:28 AM
achimlother.bsky.social
Program of the 46th International Aldosterone Conference is now online, see you July 10-11 at San Francisco, USA.
aldosterone.org
April 6, 2025 at 6:57 AM
Reposted by Achim Lother
imit-freiburg.bsky.social
Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction. New paper by Jasmin Rettkowski, Timo Heidt, Nina Cabezas-Wallscheidt and colleagues
www.nature.com/articles/s41... @achimlother.bsky.social
Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction: a preclinical study - Nature Cell Biology
Rettkowski, Romero-Mulero et al. show that myocardial infarction impacts bone marrow haematopoietic stem cells and leads to inflammatory myelopoiesis, which can be dampened by treatment with 4-oxo-ret...
www.nature.com
April 6, 2025 at 6:31 AM
Reposted by Achim Lother
imit-freiburg.bsky.social
Neue Episode von Notfallreform - how to? mit @karagiannidis.bsky.social @uniklinik-fr.bsky.social
open.spotify.com/episode/4OPd...
Notfallreform - how to? Episode III - Felix Hans & Christian Karagiannidis
Notfallreform - how to? Warum wir genau jetzt über die Notfallversorgung sprechen müssen · Episode
open.spotify.com
April 6, 2025 at 5:39 AM
Reposted by Achim Lother
epihmgu.bsky.social
🌟 SAVE THE DATE: Talent Forum 2025!

🗓️ November 18–19
📍 @www.helmholtz-munich.de‬, Germany

Showcase your research and network with global talents in #Epigenetics & Nucleic Acids Research!

Apply by July 31 for a speaker spot —travel & accommodation covered.

🔜 Website coming soon!
March 25, 2025 at 11:02 AM
achimlother.bsky.social
Excellent review, thanks to the authors for putting this together www.nature.com/articles/s41...
Fibrosis: cross-organ biology and pathways to development of innovative drugs - Nature Reviews Drug Discovery
Fibrosis is a key characteristic of a range of chronic diseases that has been challenging to target with drugs. This Review highlights core pathways active in fibrotic conditions across organs, as wel...
www.nature.com
March 21, 2025 at 6:20 PM
achimlother.bsky.social
Planning of the next ESAC meeting on aldosterone and MR is in full process. Mark your calendars and see you October 17-18 in Rome
admire-network.org/2024/05/15/s...
Save the date: ESAC Meeting 2025 – ADMIRE network
admire-network.org
March 20, 2025 at 8:22 AM