Tau buildup doesn’t just mark disease—it changes how neurons talk. 🧠
Using rPeptide’s Tau-441 PFFs, researchers found Tau aggregates shift brain signaling toward long-term depression, mirroring early Alzheimer’s disruptions.
t.ly/SmJ7G
#Neuroscience #TauProtein #AlzheimersResearch #rPeptide
Using rPeptide’s Tau-441 PFFs, researchers found Tau aggregates shift brain signaling toward long-term depression, mirroring early Alzheimer’s disruptions.
t.ly/SmJ7G
#Neuroscience #TauProtein #AlzheimersResearch #rPeptide
Incubation with tau aggregates increases hippocampal circuit excitability and enhances long-term depression in acute mouse hippocampal slices
Aggregation of the protein tau is a key pathological hallmark of tauopathies such as Alzheimer’s Disease. Tau dissociates from microtubules and diffuses from the axon into the soma-dendritic compartment, where it aggregates firstly into oligomers ...
t.ly
November 12, 2025 at 1:12 PM
Tau buildup doesn’t just mark disease—it changes how neurons talk. 🧠
Using rPeptide’s Tau-441 PFFs, researchers found Tau aggregates shift brain signaling toward long-term depression, mirroring early Alzheimer’s disruptions.
t.ly/SmJ7G
#Neuroscience #TauProtein #AlzheimersResearch #rPeptide
Using rPeptide’s Tau-441 PFFs, researchers found Tau aggregates shift brain signaling toward long-term depression, mirroring early Alzheimer’s disruptions.
t.ly/SmJ7G
#Neuroscience #TauProtein #AlzheimersResearch #rPeptide
Seasonal depression often comes back at the same time every year. 🧠 @grok
November 12, 2025 at 7:50 AM
Seasonal depression often comes back at the same time every year. 🧠 @grok
🧠💥 Did you know #Depression may be coded in your #Immune system?😲🔥Our paper shows how #Inflammation+ #Kynurenine 🧬shape the #Brain ! @mdpiopenaccess.bsky.social #DrugDiscovery #MedChem #Oncology #Neuropharma
📖Read more👉 www.mdpi.com/1424-8247/18...
📖Read more👉 www.mdpi.com/1424-8247/18...
November 12, 2025 at 6:37 AM
🧠💥 Did you know #Depression may be coded in your #Immune system?😲🔥Our paper shows how #Inflammation+ #Kynurenine 🧬shape the #Brain ! @mdpiopenaccess.bsky.social #DrugDiscovery #MedChem #Oncology #Neuropharma
📖Read more👉 www.mdpi.com/1424-8247/18...
📖Read more👉 www.mdpi.com/1424-8247/18...
Depression is trying its hardest to win yall😢 I hate having a broken brain 🧠
November 12, 2025 at 2:22 AM
Depression is trying its hardest to win yall😢 I hate having a broken brain 🧠
Prof Sarah Whittle is presenting on her labs work into the relationship between brain structural changes and depression in development 🧠💭🌱
November 11, 2025 at 11:39 PM
Prof Sarah Whittle is presenting on her labs work into the relationship between brain structural changes and depression in development 🧠💭🌱
🧵 1/7
☕🧠 THE COFFEE PARADOX IN DEPRESSION TREATMENT
New Brain Medicine commentary highlights Nature research revealing adenosine as the master regulator of rapid antidepressant action—creating a fascinating clinical dilemma.
Our analysis: dx.doi.org/10.61373/bm0...
Nature: doi.org/10.1038/s415...
☕🧠 THE COFFEE PARADOX IN DEPRESSION TREATMENT
New Brain Medicine commentary highlights Nature research revealing adenosine as the master regulator of rapid antidepressant action—creating a fascinating clinical dilemma.
Our analysis: dx.doi.org/10.61373/bm0...
Nature: doi.org/10.1038/s415...
November 11, 2025 at 4:20 PM
🧵 1/7
☕🧠 THE COFFEE PARADOX IN DEPRESSION TREATMENT
New Brain Medicine commentary highlights Nature research revealing adenosine as the master regulator of rapid antidepressant action—creating a fascinating clinical dilemma.
Our analysis: dx.doi.org/10.61373/bm0...
Nature: doi.org/10.1038/s415...
☕🧠 THE COFFEE PARADOX IN DEPRESSION TREATMENT
New Brain Medicine commentary highlights Nature research revealing adenosine as the master regulator of rapid antidepressant action—creating a fascinating clinical dilemma.
Our analysis: dx.doi.org/10.61373/bm0...
Nature: doi.org/10.1038/s415...
💡 Did you know your #Mood may start in your #Gut? 🌱🧠💔 New #Science shows #Plants hold hidden keys to #Depression relief!. Curious? Let’s dive in… 🚀✨ @mdpiopenaccess.bsky.social #Neuroscience #Depression
www.preprints.org/manuscript/2...
www.preprints.org/manuscript/2...
November 11, 2025 at 6:34 AM
💡 Did you know your #Mood may start in your #Gut? 🌱🧠💔 New #Science shows #Plants hold hidden keys to #Depression relief!. Curious? Let’s dive in… 🚀✨ @mdpiopenaccess.bsky.social #Neuroscience #Depression
www.preprints.org/manuscript/2...
www.preprints.org/manuscript/2...
🧠 Help advance research on how mental health symptoms overlap!
The MaRSS Lab is seeking cisgender women (18+) with experiences of anxiety, depression, and/or sexual dysfunction to complete a 15-min survey for a chance to win 1 of 3 $50 Amazon gift cards.
👉 uwo.eu.qualtrics.com/jfe/form/SV_...
The MaRSS Lab is seeking cisgender women (18+) with experiences of anxiety, depression, and/or sexual dysfunction to complete a 15-min survey for a chance to win 1 of 3 $50 Amazon gift cards.
👉 uwo.eu.qualtrics.com/jfe/form/SV_...
November 10, 2025 at 4:59 PM
🧠 Help advance research on how mental health symptoms overlap!
The MaRSS Lab is seeking cisgender women (18+) with experiences of anxiety, depression, and/or sexual dysfunction to complete a 15-min survey for a chance to win 1 of 3 $50 Amazon gift cards.
👉 uwo.eu.qualtrics.com/jfe/form/SV_...
The MaRSS Lab is seeking cisgender women (18+) with experiences of anxiety, depression, and/or sexual dysfunction to complete a 15-min survey for a chance to win 1 of 3 $50 Amazon gift cards.
👉 uwo.eu.qualtrics.com/jfe/form/SV_...
🧠The VA is expanding their psychedelic-assisted therapy trials for veterans diagnosed with PTSD, treatment resistant depression, and anxiety disorders.
💊If the outcomes from these trials remain positive, they could pursue FDA fast-track consideration.
💊If the outcomes from these trials remain positive, they could pursue FDA fast-track consideration.
VA Expands Psychedelic Therapy Trials for PTSD Treatment
The VA is expanding psychedelic-assisted therapy trials for PTSD and depression at nine facilities, exploring new hope for treatment-resistant veterans.
www.military.com
November 10, 2025 at 3:59 PM
🧠The VA is expanding their psychedelic-assisted therapy trials for veterans diagnosed with PTSD, treatment resistant depression, and anxiety disorders.
💊If the outcomes from these trials remain positive, they could pursue FDA fast-track consideration.
💊If the outcomes from these trials remain positive, they could pursue FDA fast-track consideration.
#Depression ist keine Schwäche, …
sondern eine Störung des wichtigen Organes …
Gehirn 🧠.
Wie bei Herz oder Niere braucht es auch hier professionelle Hilfe, bevor das Leben selbst zur letzten Konsequenz wird.
Rest in Peace, #RobertEnke – 10. November, ein Tag, der mahnt🖖
bsky.app/profile/runn...
sondern eine Störung des wichtigen Organes …
Gehirn 🧠.
Wie bei Herz oder Niere braucht es auch hier professionelle Hilfe, bevor das Leben selbst zur letzten Konsequenz wird.
Rest in Peace, #RobertEnke – 10. November, ein Tag, der mahnt🖖
bsky.app/profile/runn...
November 10, 2025 at 9:44 AM
#Depression ist keine Schwäche, …
sondern eine Störung des wichtigen Organes …
Gehirn 🧠.
Wie bei Herz oder Niere braucht es auch hier professionelle Hilfe, bevor das Leben selbst zur letzten Konsequenz wird.
Rest in Peace, #RobertEnke – 10. November, ein Tag, der mahnt🖖
bsky.app/profile/runn...
sondern eine Störung des wichtigen Organes …
Gehirn 🧠.
Wie bei Herz oder Niere braucht es auch hier professionelle Hilfe, bevor das Leben selbst zur letzten Konsequenz wird.
Rest in Peace, #RobertEnke – 10. November, ein Tag, der mahnt🖖
bsky.app/profile/runn...
Inside the diagnostic grey zone: using machine learning to separate bipolar and major depression ⚙️🧠
High misdiagnosis rates between the two cause real harm for patients and services. This new neuroimaging study tested whether brain connectivity and AI could help tell them apart.
🧵 THREAD
High misdiagnosis rates between the two cause real harm for patients and services. This new neuroimaging study tested whether brain connectivity and AI could help tell them apart.
🧵 THREAD
November 10, 2025 at 7:41 AM
Inside the diagnostic grey zone: using machine learning to separate bipolar and major depression ⚙️🧠
High misdiagnosis rates between the two cause real harm for patients and services. This new neuroimaging study tested whether brain connectivity and AI could help tell them apart.
🧵 THREAD
High misdiagnosis rates between the two cause real harm for patients and services. This new neuroimaging study tested whether brain connectivity and AI could help tell them apart.
🧵 THREAD
Your body on air pollution:
🧠 Brain: Stroke, Depression
❤️ Heart: Attacks, Failure
🤰 Pregnancy: Miscarriages, Low Birth Weight
🍯 Metabolism: Diabetes
How many more studies do we need before we ACT?
🧠 Brain: Stroke, Depression
❤️ Heart: Attacks, Failure
🤰 Pregnancy: Miscarriages, Low Birth Weight
🍯 Metabolism: Diabetes
How many more studies do we need before we ACT?
November 8, 2025 at 7:24 AM
Your body on air pollution:
🧠 Brain: Stroke, Depression
❤️ Heart: Attacks, Failure
🤰 Pregnancy: Miscarriages, Low Birth Weight
🍯 Metabolism: Diabetes
How many more studies do we need before we ACT?
🧠 Brain: Stroke, Depression
❤️ Heart: Attacks, Failure
🤰 Pregnancy: Miscarriages, Low Birth Weight
🍯 Metabolism: Diabetes
How many more studies do we need before we ACT?
Bottom line: rates of self-reported cognitive disability increasing, esp in young adults.
I don't need more business. Please take care of your 🧠
Caveats:
*I would have run this w & w/o depression
*Lack of trend in older adults may also be incr mortality from Covid in those w dementia
I don't need more business. Please take care of your 🧠
Caveats:
*I would have run this w & w/o depression
*Lack of trend in older adults may also be incr mortality from Covid in those w dementia
November 8, 2025 at 3:27 AM
Bottom line: rates of self-reported cognitive disability increasing, esp in young adults.
I don't need more business. Please take care of your 🧠
Caveats:
*I would have run this w & w/o depression
*Lack of trend in older adults may also be incr mortality from Covid in those w dementia
I don't need more business. Please take care of your 🧠
Caveats:
*I would have run this w & w/o depression
*Lack of trend in older adults may also be incr mortality from Covid in those w dementia
🧠 Can creatine help with depression? New review finds the evidence is too weak and inconsistent to recommend it as a treatment - results may not be meaningful or reliable. www.news-medical.net/news/2025110... #MentalHealth #Depression #Creatine
Can creatine help with depression? New review says results are inconclusive
Creatine supplementation may modestly reduce depressive symptoms, but the effect is small, uncertain, and likely influenced by study bias. The evidence remains of very low quality, highlighting the ne...
www.news-medical.net
November 7, 2025 at 12:15 AM
🧠 Can creatine help with depression? New review finds the evidence is too weak and inconsistent to recommend it as a treatment - results may not be meaningful or reliable. www.news-medical.net/news/2025110... #MentalHealth #Depression #Creatine
A study providing evidence that variations in DNA methylation are associated with Major Depression. It adds further evidence supporting involvement of the immune system. 🧠🧬📄
New Publication:
A methylome-wide association study of major depression with out-of-sample case–control classification and trans-ancestry comparison
@edinunineuro.bsky.social @uoe-igc.bsky.social @roslininstitute.bsky.social @edinunilbc.bsky.social
www.nature.com/articles/s44...
A methylome-wide association study of major depression with out-of-sample case–control classification and trans-ancestry comparison
@edinunineuro.bsky.social @uoe-igc.bsky.social @roslininstitute.bsky.social @edinunilbc.bsky.social
www.nature.com/articles/s44...
A methylome-wide association study of major depression with out-of-sample case–control classification and trans-ancestry comparison - Nature Mental Health
The authors report a meta-analysis of methylome-wide association studies, identifying 15 significant CpG sites linked to major depression, revealing associations with inflammatory markers and suggesti...
www.nature.com
November 6, 2025 at 6:30 PM
A study providing evidence that variations in DNA methylation are associated with Major Depression. It adds further evidence supporting involvement of the immune system. 🧠🧬📄
🧠 Stress, anxiety & depression in 16–24 year olds have risen 168% since 2000 - nearly 4x faster than the general population.
This #StressAwarenessWeek, we're spotlighting the role creativity can play in easing stress + supporting mental health.
#CreativityAndWellbeing
This #StressAwarenessWeek, we're spotlighting the role creativity can play in easing stress + supporting mental health.
#CreativityAndWellbeing
November 6, 2025 at 11:22 AM
🧠 Stress, anxiety & depression in 16–24 year olds have risen 168% since 2000 - nearly 4x faster than the general population.
This #StressAwarenessWeek, we're spotlighting the role creativity can play in easing stress + supporting mental health.
#CreativityAndWellbeing
This #StressAwarenessWeek, we're spotlighting the role creativity can play in easing stress + supporting mental health.
#CreativityAndWellbeing
A late post from this year’s World Congress of Psychiatric Genetics in Mexico! 🇲🇽
@evacschulte.bsky.social was there and got us this snapshot from our colleague @evabeins.bsky.social’s great presentation on the role of microglia in depression. 🧠🧫
We can't wait for WCPG26 in Glasgow! 🏴
#WCPG25
@evacschulte.bsky.social was there and got us this snapshot from our colleague @evabeins.bsky.social’s great presentation on the role of microglia in depression. 🧠🧫
We can't wait for WCPG26 in Glasgow! 🏴
#WCPG25
November 6, 2025 at 9:35 AM
A late post from this year’s World Congress of Psychiatric Genetics in Mexico! 🇲🇽
@evacschulte.bsky.social was there and got us this snapshot from our colleague @evabeins.bsky.social’s great presentation on the role of microglia in depression. 🧠🧫
We can't wait for WCPG26 in Glasgow! 🏴
#WCPG25
@evacschulte.bsky.social was there and got us this snapshot from our colleague @evabeins.bsky.social’s great presentation on the role of microglia in depression. 🧠🧫
We can't wait for WCPG26 in Glasgow! 🏴
#WCPG25
People with depression, anxiety, or PTSD tend to get Alzheimer's at a younger age than those without 🧠 @grok
November 6, 2025 at 5:18 AM
People with depression, anxiety, or PTSD tend to get Alzheimer's at a younger age than those without 🧠 @grok
Gymjuries introduction thread! Tell us your long-term ailments.
💪🏼A subluxing left ulnar nerve, agitated by overhead movements.
👋🏼A chronic wrist sprain that flares up during presses.
🏃🏼Shin splints.
🏋🏼Anterior lumbar disc herniation: I avoid barbell squats!
🧠Recurrent mild depression and anxiety 👍🏼👍🏼
💪🏼A subluxing left ulnar nerve, agitated by overhead movements.
👋🏼A chronic wrist sprain that flares up during presses.
🏃🏼Shin splints.
🏋🏼Anterior lumbar disc herniation: I avoid barbell squats!
🧠Recurrent mild depression and anxiety 👍🏼👍🏼
November 5, 2025 at 8:53 AM
Gymjuries introduction thread! Tell us your long-term ailments.
💪🏼A subluxing left ulnar nerve, agitated by overhead movements.
👋🏼A chronic wrist sprain that flares up during presses.
🏃🏼Shin splints.
🏋🏼Anterior lumbar disc herniation: I avoid barbell squats!
🧠Recurrent mild depression and anxiety 👍🏼👍🏼
💪🏼A subluxing left ulnar nerve, agitated by overhead movements.
👋🏼A chronic wrist sprain that flares up during presses.
🏃🏼Shin splints.
🏋🏼Anterior lumbar disc herniation: I avoid barbell squats!
🧠Recurrent mild depression and anxiety 👍🏼👍🏼
A study found women using hormone skin patches or gels for menopause had less anxiety and depression than women taking hormone pills. 🧠 @grok
November 4, 2025 at 11:18 PM
A study found women using hormone skin patches or gels for menopause had less anxiety and depression than women taking hormone pills. 🧠 @grok
Our paper accepted in BP:GOS! 🔥
Even when learning impairments look behaviorally similar across depression, bipolar, schizophrenia, their computational mechanisms differ. 🧠
👉 www.biorxiv.org/content/10.1...
Huge team effort! 💪😇👥@lnccbrown.bsky.social
#ComputationalPsychiatry #AdaptiveIntelligence
Even when learning impairments look behaviorally similar across depression, bipolar, schizophrenia, their computational mechanisms differ. 🧠
👉 www.biorxiv.org/content/10.1...
Huge team effort! 💪😇👥@lnccbrown.bsky.social
#ComputationalPsychiatry #AdaptiveIntelligence
Model-based EEG phenotyping uncovers distinct neurocomputational mechanisms underlying learning impairments across psychopathologies
Background: Major depressive disorder (MDD), bipolar disorder (BP), and schizophrenia (SCZ) involve learning impairments with poorly understood mechanisms. Understanding both the similarities and diff...
www.biorxiv.org
November 4, 2025 at 4:23 PM
Our paper accepted in BP:GOS! 🔥
Even when learning impairments look behaviorally similar across depression, bipolar, schizophrenia, their computational mechanisms differ. 🧠
👉 www.biorxiv.org/content/10.1...
Huge team effort! 💪😇👥@lnccbrown.bsky.social
#ComputationalPsychiatry #AdaptiveIntelligence
Even when learning impairments look behaviorally similar across depression, bipolar, schizophrenia, their computational mechanisms differ. 🧠
👉 www.biorxiv.org/content/10.1...
Huge team effort! 💪😇👥@lnccbrown.bsky.social
#ComputationalPsychiatry #AdaptiveIntelligence
Sound healing’s surprising power to boost emotional balance and help with depression is backed by science and ancient wisdom. 🧠🎶
alteredmindwaves.com/can-sound-he...
#SoundHealing #DepressionHelp #BrainScience #HolisticHealth #Mindfulness
alteredmindwaves.com/can-sound-he...
#SoundHealing #DepressionHelp #BrainScience #HolisticHealth #Mindfulness
Can Sound Healing Help With Depression – Expert Insights
Taking a closer look at how sound healing could affect depression uncovers some captivating insights that are certainly worth investigating further.
alteredmindwaves.com
November 3, 2025 at 6:10 PM
Sound healing’s surprising power to boost emotional balance and help with depression is backed by science and ancient wisdom. 🧠🎶
alteredmindwaves.com/can-sound-he...
#SoundHealing #DepressionHelp #BrainScience #HolisticHealth #Mindfulness
alteredmindwaves.com/can-sound-he...
#SoundHealing #DepressionHelp #BrainScience #HolisticHealth #Mindfulness
🧠 Be kind to your mind. Radiant offers LGBTQ+ & HIV-focused mental health care for ages 12+. Therapy for anxiety, depression, identity & more—because you matter. 💜
https://t.co/3sNrpt8x1Z
#LGBTQMentalHealth #YouMatter #RadiantHealthOC #MentalHealthSupport
https://t.co/3sNrpt8x1Z
#LGBTQMentalHealth #YouMatter #RadiantHealthOC #MentalHealthSupport
http://radianthealthcenters.org
t.co
November 3, 2025 at 3:51 PM
🧠 Be kind to your mind. Radiant offers LGBTQ+ & HIV-focused mental health care for ages 12+. Therapy for anxiety, depression, identity & more—because you matter. 💜
https://t.co/3sNrpt8x1Z
#LGBTQMentalHealth #YouMatter #RadiantHealthOC #MentalHealthSupport
https://t.co/3sNrpt8x1Z
#LGBTQMentalHealth #YouMatter #RadiantHealthOC #MentalHealthSupport
High levels of certain gut bacteria 🦠 at age 2 👶 predict:
🧠 how brain processes emotions at age 6
😩Anxiety/depression at age 7
These findings emphasize the need for healthy diets and reduced stress in small children.
www.powershealth.org/about-us/new...
🧠 how brain processes emotions at age 6
😩Anxiety/depression at age 7
These findings emphasize the need for healthy diets and reduced stress in small children.
www.powershealth.org/about-us/new...
A Kids Gut Health Might Influence Their Future Mental Health
www.powershealth.org
November 3, 2025 at 3:26 PM
High levels of certain gut bacteria 🦠 at age 2 👶 predict:
🧠 how brain processes emotions at age 6
😩Anxiety/depression at age 7
These findings emphasize the need for healthy diets and reduced stress in small children.
www.powershealth.org/about-us/new...
🧠 how brain processes emotions at age 6
😩Anxiety/depression at age 7
These findings emphasize the need for healthy diets and reduced stress in small children.
www.powershealth.org/about-us/new...
How does socioeconomic status 💰 impact reward processing 🧠, inflammation 🔥, and antidepressant efficacy 💊 in depression 😔?
Find out more 👇
Find out more 👇
Socioeconomic status is associated with reward processing, interleukin 1β, striatal connectivity and antidepressant outcomes in individuals with major depressive disorder: A CAN-BIND-1 report.
Major depressive disorder (MDD) is a common condition with heterogeneous risk factors.
Socioeconomic status (SES) is one such risk factor, which is negatively linked to
MDD treatment outcomes and symp...
www.bpsgos.org
November 3, 2025 at 1:38 PM
How does socioeconomic status 💰 impact reward processing 🧠, inflammation 🔥, and antidepressant efficacy 💊 in depression 😔?
Find out more 👇
Find out more 👇