Expanding the RNA polymerase biocatalyst solution space for mRNA manufacture https://www.biorxiv.org/content/10.1101/2024.01.28.577649v1
Expanding the RNA polymerase biocatalyst solution space for mRNA manufacture https://www.biorxiv.org/content/10.1101/2024.01.28.577649v1
All mRNA products are currently manufactured in in vitro transcription (IVT) reactions that utilize
www.biorxiv.org
January 29, 2024 at 1:48 AM
Expanding the RNA polymerase biocatalyst solution space for mRNA manufacture https://www.biorxiv.org/content/10.1101/2024.01.28.577649v1
Evaluating cutinase from Fusarium oxysporum as a biocatalyst for the degradation of nine synthetic polymer https://pubmed.ncbi.nlm.nih.gov/39843897/
January 24, 2025 at 3:25 PM
Evaluating cutinase from Fusarium oxysporum as a biocatalyst for the degradation of nine synthetic polymer https://pubmed.ncbi.nlm.nih.gov/39843897/
Computational design of a thermostable de novo biocatalyst for whole cell biotransformations https://www.biorxiv.org/content/10.1101/2024.10.07.617055v1
Computational design of a thermostable de novo biocatalyst for whole cell biotransformations https://www.biorxiv.org/content/10.1101/2024.10.07.617055v1
Several industrially relevant catalytic strategies have emerged over the last couple of decades, wit
www.biorxiv.org
October 8, 2024 at 5:46 AM
Computational design of a thermostable de novo biocatalyst for whole cell biotransformations https://www.biorxiv.org/content/10.1101/2024.10.07.617055v1
1/2 New paper by our PhD student Sompot Antimanon, where he uses Pseudomonas putida as a biocatalyst for cinnamic acid production in a process that increase water use efficiency. Sompot reached a TRY of T=143 g/L, R= 2.25 g/L/h, and Y 1.50 g/g glc after 8 recycles.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
High-efficiency water use and process performance for bioproduction of trans-cinnamic acid - Scientific Reports
Scientific Reports - High-efficiency water use and process performance for bioproduction of trans-cinnamic acid
www.nature.com
April 8, 2025 at 5:46 PM
1/2 New paper by our PhD student Sompot Antimanon, where he uses Pseudomonas putida as a biocatalyst for cinnamic acid production in a process that increase water use efficiency. Sompot reached a TRY of T=143 g/L, R= 2.25 g/L/h, and Y 1.50 g/g glc after 8 recycles.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Fungi meet favelines: researchers use Umbelopsis isabellina as a biocatalyst to transform plant compounds into novel bis-norditerpenes. A greener route to complex molecules!
www.sciencedirect.com/science/arti...
#Biocatalysis #GreenChemistry #NaturalProducts #Mycology
www.sciencedirect.com/science/arti...
#Biocatalysis #GreenChemistry #NaturalProducts #Mycology
New bis-norditerpene by biotransformation of favelines from Cnidoscolus quercifolius using Umbelopsis isabellina as biocatalyst
Favelines, tricyclic benzylcycloheptene diterpenes predominantly found in Cnidoscolus quercifolius, have demonstrated significant cytotoxic activity a…
www.sciencedirect.com
May 12, 2025 at 10:31 PM
Fungi meet favelines: researchers use Umbelopsis isabellina as a biocatalyst to transform plant compounds into novel bis-norditerpenes. A greener route to complex molecules!
www.sciencedirect.com/science/arti...
#Biocatalysis #GreenChemistry #NaturalProducts #Mycology
www.sciencedirect.com/science/arti...
#Biocatalysis #GreenChemistry #NaturalProducts #Mycology
Solar-hybrid biocatalyst for methane hydroxylation to methanol
->Nature | More from Lil' Dr Glen EcoChat at BigEarthData.ai
->Nature | More from Lil' Dr Glen EcoChat at BigEarthData.ai
Solar-hybrid biocatalyst for methane hydroxylation to methanol
We first examined the possibility of complex formation between the XD and MMO for solar-hybrid biocatalyst development to achieve methane conversion. To this end, we used MMOH as a model enzyme and EY as a model light-harvesting dye because MMOH...
www.nature.com
October 23, 2025 at 2:02 AM
BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions
http://biorxiv.org/cgi/content/short/2024.10.16.618725v1
October 21, 2024 at 12:28 PM
BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions
http://biorxiv.org/cgi/content/short/2024.10.16.618725v1
Great how interdisciplinary work reveal details on #enzymes regarding mechanism and application. A little #heme #protein is a versatile #biocatalyst ... and here we show the interplay of heme with a tyrosine embedded in a proton network facilitates the rare enantioselective Meinwald Rearrangement in
September 30, 2025 at 8:44 AM
Great how interdisciplinary work reveal details on #enzymes regarding mechanism and application. A little #heme #protein is a versatile #biocatalyst ... and here we show the interplay of heme with a tyrosine embedded in a proton network facilitates the rare enantioselective Meinwald Rearrangement in
[FeFe]-Hydrogenase Encapsulated in Zeolitic Imidazolate Framework (ZIF)-8 Nanoparticles as a Robust Biocatalyst for Photocatalytic Hydrogen Production http://dx.doi.org/10.1021/acssuschemeng.3c08560
April 12, 2024 at 1:13 PM
[FeFe]-Hydrogenase Encapsulated in Zeolitic Imidazolate Framework (ZIF)-8 Nanoparticles as a Robust Biocatalyst for Photocatalytic Hydrogen Production http://dx.doi.org/10.1021/acssuschemeng.3c08560
[ #visualnovels #horrorgames #pixelart ]
back in may renbie n i made a horror vn abt old men trapped in their office by a ghost btw 👻
renbie.itch.io/biocatalyst
back in may renbie n i made a horror vn abt old men trapped in their office by a ghost btw 👻
renbie.itch.io/biocatalyst
November 20, 2024 at 4:21 AM
[ #visualnovels #horrorgames #pixelart ]
back in may renbie n i made a horror vn abt old men trapped in their office by a ghost btw 👻
renbie.itch.io/biocatalyst
back in may renbie n i made a horror vn abt old men trapped in their office by a ghost btw 👻
renbie.itch.io/biocatalyst
Decoding Substrate Specificity in a Promiscuous Biocatalyst by Enzyme Proximity Sequencing [new]
Maps DAAO mut's alt. subs. Act. site & distal mut's change spec.
Maps DAAO mut's alt. subs. Act. site & distal mut's change spec.
July 16, 2025 at 3:53 AM
Decoding Substrate Specificity in a Promiscuous Biocatalyst by Enzyme Proximity Sequencing [new]
Maps DAAO mut's alt. subs. Act. site & distal mut's change spec.
Maps DAAO mut's alt. subs. Act. site & distal mut's change spec.
BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions https://www.biorxiv.org/content/10.1101/2024.10.16.618725v1
BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions https://www.biorxiv.org/content/10.1101/2024.10.16.618725v1
Enzyme-substrate interactions are essential to both biological processes and industrial applications
www.biorxiv.org
October 18, 2024 at 1:47 PM
BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions https://www.biorxiv.org/content/10.1101/2024.10.16.618725v1
An ML-guided, cell-free enzyme engineering platform for optimizing substrate preference.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 21, 2025 at 10:42 PM
An ML-guided, cell-free enzyme engineering platform for optimizing substrate preference.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Pleased for this to be our first Blue Sky post!
Just out in Nature Communications Chemistry:
Rational engineering of a thermostable α-oxoamine synthase biocatalyst expands the substrate scope and synthetic applicability
Check it out below:
www.nature.com/articles/s42...
Just out in Nature Communications Chemistry:
Rational engineering of a thermostable α-oxoamine synthase biocatalyst expands the substrate scope and synthetic applicability
Check it out below:
www.nature.com/articles/s42...
Rational engineering of a thermostable α-oxoamine synthase biocatalyst expands the substrate scope and synthetic applicability - Communications Chemistry
The α-oxoamine synthases (AOSes) are a class of pyridoxal 5’-phosphate-dependent enzymes that catalyse Claisen-like condensation of amino acids with an acyl-CoA thioester to generate α-aminoketones, h...
www.nature.com
March 14, 2025 at 9:24 AM
Pleased for this to be our first Blue Sky post!
Just out in Nature Communications Chemistry:
Rational engineering of a thermostable α-oxoamine synthase biocatalyst expands the substrate scope and synthetic applicability
Check it out below:
www.nature.com/articles/s42...
Just out in Nature Communications Chemistry:
Rational engineering of a thermostable α-oxoamine synthase biocatalyst expands the substrate scope and synthetic applicability
Check it out below:
www.nature.com/articles/s42...
"PET plastic... is usually made from crude oil & causes environmental harm at every stage of its production and life cycle.
... scientists developed a biocatalyst ...able to break down plastic in a way that mimics how natural substances decompose"
www.thecooldown.com/green-tech/k....
... scientists developed a biocatalyst ...able to break down plastic in a way that mimics how natural substances decompose"
www.thecooldown.com/green-tech/k....
Researchers stunned after discovering new method to break down plastic: 'This is a groundbreaking technology'
Scientists in South Korea have developed a new method of decomposing PET plastic, one of the most common types of plastic.
www.thecooldown.com
January 21, 2025 at 5:06 AM
"PET plastic... is usually made from crude oil & causes environmental harm at every stage of its production and life cycle.
... scientists developed a biocatalyst ...able to break down plastic in a way that mimics how natural substances decompose"
www.thecooldown.com/green-tech/k....
... scientists developed a biocatalyst ...able to break down plastic in a way that mimics how natural substances decompose"
www.thecooldown.com/green-tech/k....
A newly developed biocatalyst efficiently converts styrene pollutants into pure epoxides, supporting sustainable production of pharmaceuticals and specialty chemicals through high selectivity. doi.org/g9sm7p
Selective biocatalyst targets styrene pollutant, yielding pure epoxides for pharmaceuticals and specialty chemicals
Doctoral students have described a new selective biocatalyst in an interdisciplinary and inter-university collaboration.
phys.org
July 8, 2025 at 8:02 PM
A newly developed biocatalyst efficiently converts styrene pollutants into pure epoxides, supporting sustainable production of pharmaceuticals and specialty chemicals through high selectivity. doi.org/g9sm7p
This #EHUikerketa develops a self-sufficient heterogeneous biocatalyst (ssHB) composed of two NADH-dependent dehydrogenases co-immobilized with NADH on porous supports.
Orthogonal Valorization of 5‐Hydroxymethylfurfural Using Self‐Sufficient Heterogeneous Biocatalysts Composed of Two Co‐Immobilized Dehydrogenases
A self-sufficient heterogeneous biocatalyst (ssHB) composed of two NADH-dependent dehydrogenases co-immobilized with NADH on porous supports enables the redox disproportionation of HMF, yielding bot...
chemistry-europe.onlinelibrary.wiley.com
October 11, 2025 at 7:05 PM
This #EHUikerketa develops a self-sufficient heterogeneous biocatalyst (ssHB) composed of two NADH-dependent dehydrogenases co-immobilized with NADH on porous supports.
BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions https://www.biorxiv.org/content/10.1101/2024.10.16.618725v1
BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions https://www.biorxiv.org/content/10.1101/2024.10.16.618725v1
Enzyme-substrate interactions are essential to both biological processes and industrial applications
www.biorxiv.org
October 18, 2024 at 1:47 PM
BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions https://www.biorxiv.org/content/10.1101/2024.10.16.618725v1
Decoding Substrate Specificity in a Promiscuous Biocatalyst by Enzyme Proximity Sequencing https://www.biorxiv.org/content/10.1101/2025.07.10.664162v1
July 16, 2025 at 3:46 AM
Decoding Substrate Specificity in a Promiscuous Biocatalyst by Enzyme Proximity Sequencing https://www.biorxiv.org/content/10.1101/2025.07.10.664162v1
Carbon Negative Synthesis of Amino Acids Using a Cell-Free-Based Biocatalyst | ACS Synthetic Biology pubs.acs.org/doi/10.1021/...
Carbon Negative Synthesis of Amino Acids Using a Cell-Free-Based Biocatalyst
Biological systems can directly upgrade carbon dioxide (CO2) into chemicals. The CO2 fixation rate of autotrophic organisms, however, is too slow for industrial utility, and the breadth of engineered ...
pubs.acs.org
November 22, 2024 at 7:08 PM
Carbon Negative Synthesis of Amino Acids Using a Cell-Free-Based Biocatalyst | ACS Synthetic Biology pubs.acs.org/doi/10.1021/...
Former Queensland Premier Peter Beattie has been named new chair of Brandon BioCatalyst, replacing one of the founding fathers of Australian venture capital, Bill Ferris, who is retiring from the role
Brandon BioCatalyst names Peter Beattie as new chairman to champion biotech startups
Brandon BioCatalyst names Peter Beattie as new chairman to champion biotech startups
zpr.io
August 19, 2025 at 6:46 AM
Former Queensland Premier Peter Beattie has been named new chair of Brandon BioCatalyst, replacing one of the founding fathers of Australian venture capital, Bill Ferris, who is retiring from the role
New paper from the #elkcrew: As you can see from the list of authors, a lot of thought and work went into this one. Thank you all!
"Racemization-free and scalable amidation of l-proline in organic media using ammonia and a biocatalyst only"...
"Racemization-free and scalable amidation of l-proline in organic media using ammonia and a biocatalyst only"...
May 6, 2025 at 12:27 PM
New paper from the #elkcrew: As you can see from the list of authors, a lot of thought and work went into this one. Thank you all!
"Racemization-free and scalable amidation of l-proline in organic media using ammonia and a biocatalyst only"...
"Racemization-free and scalable amidation of l-proline in organic media using ammonia and a biocatalyst only"...
Overexpression of native carbonic anhydrases increases carbon conversion efficiency in the methanotrophic biocatalyst Methylococcus capsulatus Bath journals.asm.org/doi/full/10.... #jcampubs
August 29, 2024 at 1:45 PM
Overexpression of native carbonic anhydrases increases carbon conversion efficiency in the methanotrophic biocatalyst Methylococcus capsulatus Bath journals.asm.org/doi/full/10.... #jcampubs
This NAS report highlights transformative convergence of biotechnology, AI, & automation for defense & global partnerships. The proposed BioCATALYST network invites allied collaboration, shaping ethical norms & safeguarding against misuse, advancing shared security & innovation. lnkd.in/eT-FiTGt
November 26, 2024 at 1:14 PM
This NAS report highlights transformative convergence of biotechnology, AI, & automation for defense & global partnerships. The proposed BioCATALYST network invites allied collaboration, shaping ethical norms & safeguarding against misuse, advancing shared security & innovation. lnkd.in/eT-FiTGt
## 연구 제목: 고체 생물 촉매 기반의 고효율 바이오디젤 생산을 위한 반응 공정 최적화 및 에너지 효율 극대화 연구
### 1. 연구 배경 최근 기후 변화 대응과 지속 가능한 에너지 확보의 중요성이 강조되면서, 바이오 연료가 지속 가능한 에너지원으로 주목받고 있습니다. 특히, 바이오디젤은 화석 연료를 대체할 수 있는 잠재력을 가진 유망한 대안입니다. 바이오디젤 생산 기술은 다양한 연구 분야와의 융합을 통해 지속적으로 발전해 왔으며, 특히 생물 촉매(biocatalyst)를 활용한 생산 방식은 기존 화학 촉매 방식에 비해…
### 1. 연구 배경 최근 기후 변화 대응과 지속 가능한 에너지 확보의 중요성이 강조되면서, 바이오 연료가 지속 가능한 에너지원으로 주목받고 있습니다. 특히, 바이오디젤은 화석 연료를 대체할 수 있는 잠재력을 가진 유망한 대안입니다. 바이오디젤 생산 기술은 다양한 연구 분야와의 융합을 통해 지속적으로 발전해 왔으며, 특히 생물 촉매(biocatalyst)를 활용한 생산 방식은 기존 화학 촉매 방식에 비해…
## 연구 제목: 고체 생물 촉매 기반의 고효율 바이오디젤 생산을 위한 반응 공정 최적화 및 에너지 효율 극대화 연구
### 1. 연구 배경 최근 기후 변화 대응과 지속 가능한 에너지 확보의 중요성이 강조되면서, 바이오 연료가 지속 가능한 에너지원으로 주목받고 있습니다. 특히, 바이오디젤은 화석 연료를 대체할 수 있는 잠재력을 가진 유망한 대안입니다. 바이오디젤 생산 기술은 다양한 연구 분야와의 융합을 통해 지속적으로 발전해 왔으며, 특히 생물 촉매(biocatalyst)를 활용한 생산 방식은 기존 화학 촉매 방식에 비해 친환경적이고 에너지 효율적인 측면에서 강점을 보입니다.
freederia.com
April 19, 2025 at 3:30 AM
## 연구 제목: 고체 생물 촉매 기반의 고효율 바이오디젤 생산을 위한 반응 공정 최적화 및 에너지 효율 극대화 연구
### 1. 연구 배경 최근 기후 변화 대응과 지속 가능한 에너지 확보의 중요성이 강조되면서, 바이오 연료가 지속 가능한 에너지원으로 주목받고 있습니다. 특히, 바이오디젤은 화석 연료를 대체할 수 있는 잠재력을 가진 유망한 대안입니다. 바이오디젤 생산 기술은 다양한 연구 분야와의 융합을 통해 지속적으로 발전해 왔으며, 특히 생물 촉매(biocatalyst)를 활용한 생산 방식은 기존 화학 촉매 방식에 비해…
### 1. 연구 배경 최근 기후 변화 대응과 지속 가능한 에너지 확보의 중요성이 강조되면서, 바이오 연료가 지속 가능한 에너지원으로 주목받고 있습니다. 특히, 바이오디젤은 화석 연료를 대체할 수 있는 잠재력을 가진 유망한 대안입니다. 바이오디젤 생산 기술은 다양한 연구 분야와의 융합을 통해 지속적으로 발전해 왔으며, 특히 생물 촉매(biocatalyst)를 활용한 생산 방식은 기존 화학 촉매 방식에 비해…