#YolTech
YOLT-101
Another single-infusion #BaseEditor therapy for Heterozygous Familial Hypercholesterolemia
From #YolTech Therapeutics

0.6 mg/kg N=3
Being effective in 1 wk
Sustained 70% ⬇️plasma PCSk9 & 50% ⬇️LDL-C till 16-wk

medRxiv 2025
www.medrxiv.org/content/10.1...
November 11, 2025 at 8:04 PM
#Yoltech with #China investigator-initiated n=6 #PCSK9 base editor data.

Very similar approach to $verv, sees 50%LDLc lowering, but 50% with 'mild' liver enzme elevations.

www.prnewswire.com/news-release...
YolTech Announces First Clinical Data from Ongoing Investigator-Initiated Trial of YOLT-101, An In-Vivo Base Editing Therapy for Familial Hypercholesterolemia
/PRNewswire/ -- YolTech Therapeutics Co.,Ltd, a clinical-stage in vivo gene editing company committed to pioneering the next generation of precision genetic...
www.prnewswire.com
April 28, 2025 at 12:00 PM
YolTech Therapeutics Secures $45 Million in Series B Funding to Advance Gene-Editing Therapies#China#Shanghai#YolTech_Therapeutics#gene-editing#AstraZeneca-CICC
YolTech Therapeutics Secures $45 Million in Series B Funding to Advance Gene-Editing Therapies
YolTech Therapeutics has successfully raised $45 million in Series B funding, led by AstraZeneca-CICC, to progress its innovative gene-editing therapies.
third-news.com
September 11, 2025 at 12:27 PM
YolTech Therapeutics Unveils Promising Results for YOLT-203, Targeting Primary Hyperoxaluria Type 1#China#Shanghai#YOLT-203#YolTech_Therapeutics#PH1
YolTech Therapeutics Unveils Promising Results for YOLT-203, Targeting Primary Hyperoxaluria Type 1
YolTech Therapeutics shares encouraging data on YOLT-203, an innovative gene-editing treatment for Primary Hyperoxaluria Type 1, showcasing safety and efficacy.
third-news.com
February 25, 2025 at 8:20 AM
Chinese #CRISPR company YolTech Therapeutics has raised a $45M series B as it plans for its first Phase 3 study in ATTR, the same genetic disease that US-based Intellia recently began a pair of Phase 3 studies in. Read more in my exclusive for
@endpts.com: endpoints.news/chinese-cris...
Exclusive: Chinese CRISPR company YolTech raises $45M as it plans for first Phase 3 study
YolTech Therapeutics raises $44.5M Series B for CRISPR therapies, led by AstraZeneca-CICC fund. Company has 4 therapies in clinical trials, plans Phase 3 for ATTR treatment.
endpoints.news
September 10, 2025 at 3:33 PM
Thoughts on this? >> YolTech Therapeutics Announces FDA Clearance of
Investigational New Drug (IND) Application for YOLT-101, an In Vivo
Base Editing Therapy to Treat Heterozygous Familial
Hypercholesterolemia (HeFH) >> Comment below! #mhealth #industry40 #AI #IoT #healthtech
YolTech Therapeutics Announces FDA Clearance of Investigational New Drug (IND) Application for YOLT-101, an In Vivo Base Editing Therapy to Treat Heterozygous Familial Hypercholesterolemia (HeFH)
SHANGHAI, June 5, 2025 /PRNewswire/ — YolTech Therapeutics, a clinical-stage biotechnology company developing in vivo genome editing therapies, today announced that the U.S. Food and Drug Administration (FDA) has cleared the company’s Investigational New Drug (IND) application for YOLT-101, an in vivo base editing therapy targeting PCSK9 for the treatment of heterozygous familial hypercholesterolemia (HeFH). “The FDA …
dlvr.it
June 6, 2025 at 5:46 AM
YolTech Therapeutics becomes the latest Chinese company to get ahead of the US with a clinical trial of an experimental CRISPR therapy.
endpts.com/chinese-star...
Chinese startup begins first trial of in vivo CRISPR therapy for blood disease
A little-known Chinese biotech startup has zipped ahead of US companies in one of the gene editing field’s most competitive races.
endpts.com
January 23, 2025 at 3:49 PM
YolTech raised $45M to advance its CRISPR therapies, aiming for its first Phase 3 trial at a time when US rivals are scaling back and investors are eyeing China’s biotech scene.
Exclusive: Chinese CRISPR company YolTech raises $45M as it plans for first Phase 3 study
YolTech Therapeutics raises $44.5M Series B for CRISPR therapies, led by AstraZeneca-CICC fund. Company has 4 therapies in clinical trials, plans Phase 3 for ATTR treatment.
endpoints.news
September 10, 2025 at 8:51 PM
YolTech earns FDA IND clearance for YOLT-101—its breakthrough gene-editing therapy for familial hypercholesterolemia.

A milestone in next-gen treatments.

Read More: https://tinyurl.com/ec3pjf43

#genetherapy #ittechpulse #bestplacetowork
June 6, 2025 at 4:08 PM
YolTech Therapeutics reports positive clinical data for the first in vivo gene-editing therapy in primary hyperoxaluria type 1, Precision BioSciences demonstrates encouraging initial clinical data for PBGENE-HBV in chronic hepatitis B patients, and AccurEdit crisprmedicinenews.com/news/the-lat...
News: The Latest Updates From the Gene-Editing Clinical Trials (February 2025) - CRISPR Medicine
YolTech Therapeutics reports positive clinical data for the first in vivo gene-editing therapy in primary hyperoxaluria type 1, Precision BioSciences demonstrates encouraging initial clinical data for...
crisprmedicinenews.com
February 26, 2025 at 9:59 PM
YolTech Therapeutics Receives FDA Orphan Drug Designations for Innovative Gene Therapy YOLT-203#China#Shanghai#FDA_Approval#YolTech#YOLT-203
YolTech Therapeutics Receives FDA Orphan Drug Designations for Innovative Gene Therapy YOLT-203
YolTech Therapeutics has achieved significant FDA designations for its gene therapy YOLT-203, aimed at treating primary hyperoxaluria type 1, promising hope for affected patients.
third-news.com
December 27, 2024 at 3:20 PM
YolTech Therapeutics Advances Phase I Trial of YOLT-201 for ATTR with Successful Dose Escalation Results#China#Shanghai#YOLTx#CRISPR#ATTR
YolTech Therapeutics Advances Phase I Trial of YOLT-201 for ATTR with Successful Dose Escalation Results
YolTech Therapeutics has successfully completed the dose escalation phase in its Phase I/IIa trial for YOLT-201, a groundbreaking CRISPR/Cas9 gene-editing treatment for ATTR amyloidosis.
third-news.com
December 21, 2024 at 8:29 AM