I gotta say it is p interesting that there’s apparently a neurotransmitter (vasopressin) which makes creatures more likely to monogamously pair up, to the point that you can induce monogamous pair-bonding in otherwise promiscuous male mice by giving them vasopressin?!
November 9, 2025 at 2:46 PM
I gotta say it is p interesting that there’s apparently a neurotransmitter (vasopressin) which makes creatures more likely to monogamously pair up, to the point that you can induce monogamous pair-bonding in otherwise promiscuous male mice by giving them vasopressin?!
HRS-AKI vasoconstrictors:
Midodrine 5–15 mg TID + Octreotide 100–200 mcg SQ TID: floor-friendly, cheap, but ~10–15%.
Vasopressin 0.01–0.04 U/min or Terlipressin 1–2 mg IV q4–6h: ~50%; watch ischemia/resp.
Norepi: effective, needs ICU. #KidneyWk
Midodrine 5–15 mg TID + Octreotide 100–200 mcg SQ TID: floor-friendly, cheap, but ~10–15%.
Vasopressin 0.01–0.04 U/min or Terlipressin 1–2 mg IV q4–6h: ~50%; watch ischemia/resp.
Norepi: effective, needs ICU. #KidneyWk
November 6, 2025 at 5:43 PM
HRS-AKI vasoconstrictors:
Midodrine 5–15 mg TID + Octreotide 100–200 mcg SQ TID: floor-friendly, cheap, but ~10–15%.
Vasopressin 0.01–0.04 U/min or Terlipressin 1–2 mg IV q4–6h: ~50%; watch ischemia/resp.
Norepi: effective, needs ICU. #KidneyWk
Midodrine 5–15 mg TID + Octreotide 100–200 mcg SQ TID: floor-friendly, cheap, but ~10–15%.
Vasopressin 0.01–0.04 U/min or Terlipressin 1–2 mg IV q4–6h: ~50%; watch ischemia/resp.
Norepi: effective, needs ICU. #KidneyWk
Connectivity and phenotype of vasopressin 1a receptor cells in the lateral septum https://www.biorxiv.org/content/10.1101/2025.10.26.683946v1
October 27, 2025 at 8:15 AM
Connectivity and phenotype of vasopressin 1a receptor cells in the lateral septum https://www.biorxiv.org/content/10.1101/2025.10.26.683946v1
Apparently they’re called “arginine vasopressin disorders” and not “diabetes insipidus” anymore.
No one told me
No one told me
October 25, 2025 at 4:21 PM
Apparently they’re called “arginine vasopressin disorders” and not “diabetes insipidus” anymore.
No one told me
No one told me
Perspective by Richard H. Sterns and Helbert Rondon-Berrios:
Revisiting New Data on the Mortality Benefit of Rapid Correction of Hyponatremia: Déjà vu All Over Again
bit.ly/42Sl41K
Revisiting New Data on the Mortality Benefit of Rapid Correction of Hyponatremia: Déjà vu All Over Again
bit.ly/42Sl41K
October 23, 2025 at 4:03 PM
Perspective by Richard H. Sterns and Helbert Rondon-Berrios:
Revisiting New Data on the Mortality Benefit of Rapid Correction of Hyponatremia: Déjà vu All Over Again
bit.ly/42Sl41K
Revisiting New Data on the Mortality Benefit of Rapid Correction of Hyponatremia: Déjà vu All Over Again
bit.ly/42Sl41K
Targeting the brain's vasopressin neurons could be a novel treatment for high blood pressure
📹 Ning Gu et al @mashapk.bsky.social lab @mcgilluniversity.bsky.social in @cp-neuron.bsky.social
➡️ bpod.org.uk/archive/2025... with
@rooph.bsky.social
📹 Ning Gu et al @mashapk.bsky.social lab @mcgilluniversity.bsky.social in @cp-neuron.bsky.social
➡️ bpod.org.uk/archive/2025... with
@rooph.bsky.social
September 20, 2025 at 9:31 AM
Targeting the brain's vasopressin neurons could be a novel treatment for high blood pressure
📹 Ning Gu et al @mashapk.bsky.social lab @mcgilluniversity.bsky.social in @cp-neuron.bsky.social
➡️ bpod.org.uk/archive/2025... with
@rooph.bsky.social
📹 Ning Gu et al @mashapk.bsky.social lab @mcgilluniversity.bsky.social in @cp-neuron.bsky.social
➡️ bpod.org.uk/archive/2025... with
@rooph.bsky.social
Amazing conference and time in Erice "NEUROMODULATORS OF CONNECTION: CUTTING-EDGE INSIGHTS ON OXYTOCIN AND VASOPRESSIN IN SOCIAL BEHAVIOR, COGNITION AND THERAPY". Thank you so much for organizing it!😍
September 15, 2025 at 9:54 AM
Amazing conference and time in Erice "NEUROMODULATORS OF CONNECTION: CUTTING-EDGE INSIGHTS ON OXYTOCIN AND VASOPRESSIN IN SOCIAL BEHAVIOR, COGNITION AND THERAPY". Thank you so much for organizing it!😍
Heading home after a great few days in Erice for the ‘Neuromodulators of Connection’ meeting 🇮🇹 This is one of my favorite meetings as it focuses on oxytocin and vasopressin research AND the location in an old medieval village is super cool
September 14, 2025 at 9:14 AM
Heading home after a great few days in Erice for the ‘Neuromodulators of Connection’ meeting 🇮🇹 This is one of my favorite meetings as it focuses on oxytocin and vasopressin research AND the location in an old medieval village is super cool
The evidence from the RCTs is more peripheral ischemia, less arrhythmia and AKI with vasopressin.
December 1, 2024 at 6:32 PM
The evidence from the RCTs is more peripheral ischemia, less arrhythmia and AKI with vasopressin.
Vasopressin Synthesis
mastodon.social/@nikshahxai/...
x.com/nikshahxai/s...
nikhil.blog/2025/01/21/m...
mastodon.social/@nikshahxai/...
x.com/nikshahxai/s...
nikhil.blog/2025/01/21/m...
Nik Shah (@nikshahxai@mastodon.social)
Vasopressin Synthesis Essentials
https://x.com/nikshahxai/status/1885838744562942175
https://nikhil.blog/2025/01/21/mastering-vasopressin-synthesis-production-and-availability-by-nik-shah-2/
mastodon.social
February 3, 2025 at 4:21 PM
Vasopressin Synthesis
mastodon.social/@nikshahxai/...
x.com/nikshahxai/s...
nikhil.blog/2025/01/21/m...
mastodon.social/@nikshahxai/...
x.com/nikshahxai/s...
nikhil.blog/2025/01/21/m...
weniger Noradrenalin/Vasopressin ggf. Nitro erwägen (wenn ohne Vasopressor zu hoch)
· In Ordnung? Ab zu Punkt 3
· In Ordnung? Ab zu Punkt 3
September 29, 2023 at 7:09 AM
weniger Noradrenalin/Vasopressin ggf. Nitro erwägen (wenn ohne Vasopressor zu hoch)
· In Ordnung? Ab zu Punkt 3
· In Ordnung? Ab zu Punkt 3
So, stress amplifies our coping strategies: Colocalization of the 2 stress-sensitive peptides, CRH (green) and vasopressin (red), is augmented in adult hypothalamus after early-life stress #FluorescenceFriday 🧪🧠 #NeurobiologyofStress
February 21, 2025 at 8:51 PM
So, stress amplifies our coping strategies: Colocalization of the 2 stress-sensitive peptides, CRH (green) and vasopressin (red), is augmented in adult hypothalamus after early-life stress #FluorescenceFriday 🧪🧠 #NeurobiologyofStress
Next am, pt was more alert, w Na 157, HCO3 18. Norepi gtt off and vaso at 0.03. Some data suggest that pts on norepi + vasopressin may be less likely to develop recurrentt hypotension if vasopressin is the last pressor to be stopped. 👉 DOI: 10.1177/0885066617714209
November 19, 2024 at 3:53 PM
Next am, pt was more alert, w Na 157, HCO3 18. Norepi gtt off and vaso at 0.03. Some data suggest that pts on norepi + vasopressin may be less likely to develop recurrentt hypotension if vasopressin is the last pressor to be stopped. 👉 DOI: 10.1177/0885066617714209
Selepressin Acetate (CAS Not Available) – GMP Manufacturer
Selepressin Acetate (Purity 98.77%) is a potent selective vasopressin V1A receptor agonist widely used in research involving septic shock and vascular regulation. Manufactured under GMP conditions, it supports wholesale and retail…
Selepressin Acetate (Purity 98.77%) is a potent selective vasopressin V1A receptor agonist widely used in research involving septic shock and vascular regulation. Manufactured under GMP conditions, it supports wholesale and retail…
Selepressin Acetate (CAS Not Available) – GMP Manufacturer
Selepressin Acetate (Purity 98.77%) is a potent selective vasopressin V1A receptor agonist widely used in research involving septic shock and vascular regulation. Manufactured under GMP conditions, it supports wholesale and retail purchases strictly for experimental use.（For wholesale prices, other specifications and uses, please consult our staff）
arizona-mall.com
August 12, 2025 at 4:13 PM
Selepressin Acetate (CAS Not Available) – GMP Manufacturer
Selepressin Acetate (Purity 98.77%) is a potent selective vasopressin V1A receptor agonist widely used in research involving septic shock and vascular regulation. Manufactured under GMP conditions, it supports wholesale and retail…
Selepressin Acetate (Purity 98.77%) is a potent selective vasopressin V1A receptor agonist widely used in research involving septic shock and vascular regulation. Manufactured under GMP conditions, it supports wholesale and retail…
Scientists Uncover How Autism-Linked Mutation Lowers Vasopressin and Impacts Social Behavior - SCIENMAG
SHHHH , no one tell RFK Jr
SHHHH , no one tell RFK Jr
September 5, 2025 at 9:48 AM
Scientists Uncover How Autism-Linked Mutation Lowers Vasopressin and Impacts Social Behavior - SCIENMAG
SHHHH , no one tell RFK Jr
SHHHH , no one tell RFK Jr
Nå det har att göra med aquaporinerna och vasopressinet. Aquaporin är portar i lipidcellmembranet som gör att vattenmolekyler kan ta sig in i celler. Hormonet vasopressin reglerar hur många de är. Alkohol nedreglerar vasopressin -> färre aquaporinportar -> uttorkning. Så varannan vatten behövs :)
July 10, 2024 at 11:58 AM
Nå det har att göra med aquaporinerna och vasopressinet. Aquaporin är portar i lipidcellmembranet som gör att vattenmolekyler kan ta sig in i celler. Hormonet vasopressin reglerar hur många de är. Alkohol nedreglerar vasopressin -> färre aquaporinportar -> uttorkning. Så varannan vatten behövs :)
Nephrogenic syndrome of inappropriate diuresis: differentiate from SIADH based on very low vasopressin levels in NSIAD
November 17, 2024 at 3:24 PM
Nephrogenic syndrome of inappropriate diuresis: differentiate from SIADH based on very low vasopressin levels in NSIAD
I’ll assess the patient, particularly their peripheries and heart rate. If I’m not happy, then low threshold for adrenaline challenge. If I am happy, then at around 15mcg/min, I might look at adding vasopressin. Other factors such as renal hit might make me lean into it a bit sooner 🤷🏼
November 27, 2024 at 11:53 AM
I’ll assess the patient, particularly their peripheries and heart rate. If I’m not happy, then low threshold for adrenaline challenge. If I am happy, then at around 15mcg/min, I might look at adding vasopressin. Other factors such as renal hit might make me lean into it a bit sooner 🤷🏼
Not much at all:
oxytocin, vasopressin, CRF, PACAP/VIP, Orexin/hypocretin, NPY, Somatostatin, Substance P, Cholecytokinin, Galanin, Nociceptin, Neuropeptide S, Neurotensinm mu/kappa/delta opiod receptors, endocannabinoid, adenosines.
Overall it's pretty simple.
oxytocin, vasopressin, CRF, PACAP/VIP, Orexin/hypocretin, NPY, Somatostatin, Substance P, Cholecytokinin, Galanin, Nociceptin, Neuropeptide S, Neurotensinm mu/kappa/delta opiod receptors, endocannabinoid, adenosines.
Overall it's pretty simple.
September 4, 2025 at 4:56 PM
Not much at all:
oxytocin, vasopressin, CRF, PACAP/VIP, Orexin/hypocretin, NPY, Somatostatin, Substance P, Cholecytokinin, Galanin, Nociceptin, Neuropeptide S, Neurotensinm mu/kappa/delta opiod receptors, endocannabinoid, adenosines.
Overall it's pretty simple.
oxytocin, vasopressin, CRF, PACAP/VIP, Orexin/hypocretin, NPY, Somatostatin, Substance P, Cholecytokinin, Galanin, Nociceptin, Neuropeptide S, Neurotensinm mu/kappa/delta opiod receptors, endocannabinoid, adenosines.
Overall it's pretty simple.
Basis of nocturnal polyuria in patients with autonomic failure (1974)
pmc.ncbi.nlm.nih.gov/articles/PMC...
Very interesting paper on MSA patients. Authors suggest excessive vasopressin (AVP, also called ADH) release when upright, and excessive AVP inhibition when lying down 🧵
pmc.ncbi.nlm.nih.gov/articles/PMC...
Very interesting paper on MSA patients. Authors suggest excessive vasopressin (AVP, also called ADH) release when upright, and excessive AVP inhibition when lying down 🧵
pmc.ncbi.nlm.nih.gov
September 10, 2025 at 10:20 PM
Basis of nocturnal polyuria in patients with autonomic failure (1974)
pmc.ncbi.nlm.nih.gov/articles/PMC...
Very interesting paper on MSA patients. Authors suggest excessive vasopressin (AVP, also called ADH) release when upright, and excessive AVP inhibition when lying down 🧵
pmc.ncbi.nlm.nih.gov/articles/PMC...
Very interesting paper on MSA patients. Authors suggest excessive vasopressin (AVP, also called ADH) release when upright, and excessive AVP inhibition when lying down 🧵
☕ Coffee: diuretic or hydrator?
A new study by Fredrika Schill et al. explores how #coffee intake interacts with #vasopressin, the hormone that regulates fluid balance - offering fresh insights into the science of your daily brew.
📰Read here: doi.org/10.1530/EC-2...
A new study by Fredrika Schill et al. explores how #coffee intake interacts with #vasopressin, the hormone that regulates fluid balance - offering fresh insights into the science of your daily brew.
📰Read here: doi.org/10.1530/EC-2...
September 16, 2025 at 9:21 AM
☕ Coffee: diuretic or hydrator?
A new study by Fredrika Schill et al. explores how #coffee intake interacts with #vasopressin, the hormone that regulates fluid balance - offering fresh insights into the science of your daily brew.
📰Read here: doi.org/10.1530/EC-2...
A new study by Fredrika Schill et al. explores how #coffee intake interacts with #vasopressin, the hormone that regulates fluid balance - offering fresh insights into the science of your daily brew.
📰Read here: doi.org/10.1530/EC-2...
The Lysosome Surface is an Unappreciated Hub for Vasopressin V2 Receptor Signaling https://www.biorxiv.org/content/10.1101/2025.10.03.680346v1
October 5, 2025 at 2:30 AM
The Lysosome Surface is an Unappreciated Hub for Vasopressin V2 Receptor Signaling https://www.biorxiv.org/content/10.1101/2025.10.03.680346v1
Lauzier et al from 2006
💥23 pts w/septic shock
💥Vasopressin v NE. Equal BPs at 48 hrs, however NE required in 36% of vaso patients to do so
💥Better CrCl in the vasopressin group
https://pubmed.ncbi.nlm.nih.gov/17019548/
💥23 pts w/septic shock
💥Vasopressin v NE. Equal BPs at 48 hrs, however NE required in 36% of vaso patients to do so
💥Better CrCl in the vasopressin group
https://pubmed.ncbi.nlm.nih.gov/17019548/
November 16, 2024 at 7:31 PM
Lauzier et al from 2006
💥23 pts w/septic shock
💥Vasopressin v NE. Equal BPs at 48 hrs, however NE required in 36% of vaso patients to do so
💥Better CrCl in the vasopressin group
https://pubmed.ncbi.nlm.nih.gov/17019548/
💥23 pts w/septic shock
💥Vasopressin v NE. Equal BPs at 48 hrs, however NE required in 36% of vaso patients to do so
💥Better CrCl in the vasopressin group
https://pubmed.ncbi.nlm.nih.gov/17019548/
Correct - putting patients on Vasopressin without controlling the effect on SV is a crime - I have seen patient deteriorate very fast. But on the other hand, patients with "healthy" hearts, handle increased afterload without SV drop, so in some ways you have uncovered an issue - NE masks a lot
November 30, 2024 at 11:18 AM
Correct - putting patients on Vasopressin without controlling the effect on SV is a crime - I have seen patient deteriorate very fast. But on the other hand, patients with "healthy" hearts, handle increased afterload without SV drop, so in some ways you have uncovered an issue - NE masks a lot