#Synthesized
Wikipedia HERO

A guy discovered a faked photo of a rare blue gas on Wikipedia. So he SYNTHESIZED THE GAS HIMSELF so that he could photograph it. Yesterday he updated the article with this real photo of trifluoronitrosomethane:
November 8, 2025 at 8:51 PM
#MusicChallenge
#NewWaveNovember
Day 8

Soft Cell- Tainted Love

Originally recorded by Gloria Jones in 1964, Soft Cell's synthesized reworked version gave the song a darker edge. The song reached number 1 in the UK and number 8 on the US billboard chart.

youtu.be/XZVpR3Pk-r8?...
Soft Cell - Tainted Love (Official Music Video)
YouTube video by SoftCellVEVO
youtu.be
November 8, 2025 at 10:14 PM
Pioneer SX-D5000
Quartz Synthesized AM/FM Receiver (1980-81)

Power output: 80 watts per channel into 8Ω (stereo)

Frequency response: 20Hz to 20kHz

Total harmonic distortion: 0.005%
November 7, 2025 at 6:24 PM
Just had my first experience with an synthesized voice "AI" answering the phone at a business (called to make a restaurant reservation) and it resulted in the bot texting me a link to OpenTable that doesn't work 👍
November 7, 2025 at 9:27 PM
This paper was a pleasure to read as review editor! Congrats to the authors! For others, eNeuro has the best review process in town with a synthesized review by the editor in consultation with reviewers!
#eNeuro | The Ventral Pallidum Innervates a Distinct Subset of Midbrain Dopamine Neurons
vist.ly/4dgyn
The Ventral Pallidum Innervates a Distinct Subset of Midbrain Dopamine Neurons
Aberrant dopamine transmission is a hallmark of several psychiatric disorders. Dopamine neurons in the ventral tegmental area (VTA) display distinct activity states that are regulated by discrete afferent inputs. For example, burst firing requires excitatory input from the mesopontine tegmentum, while dopamine neuron population activity, defined as the number of spontaneously active dopamine neurons, is thought to be dependent on inhibitory drive from the ventral pallidum (VP). Rodent models used to study psychiatric disorders, such as psychosis, consistently exhibit elevated dopamine neuron population activity, due to decreased tonic inhibition from the VP. However, it remains unclear whether the VP can modulate all dopamine neurons or if only a specific subset of VTA dopamine neurons receive innervation from the VP to be recruited as required. This knowledge is critical for understanding dopamine regulation in normal and pathological conditions. Here, we used in vivo electrophysiology in male and female rats to record VTA dopamine neurons inhibited by electrical stimulation of the VP. Specifically, VP stimulation inhibited ∼22% of spontaneously active dopamine neurons; however, activation of the ventral hippocampus, a modulator of VTA population activity, increased the proportion to ∼48%. This increase suggests that VP selectively modulates a subset of dopamine neurons that can be recruited by afferent activation. Anterograde monosynaptic tracing revealed that approximately half of the VTA dopamine neurons receive input from the VP. Taken together, we demonstrate that a subset of VTA dopamine neurons receives monosynaptic input from the VP, providing valuable information regarding the regulation of VTA neuron activity.
doi.org
November 8, 2025 at 7:37 PM
Most modern medicines didn't exist a half century ago. Human insulin was first synthesized in 1978. It entered the mass market in 1982. Dynamic pacemakers were first constructed in 1982. Many chemotherapy drugs are just a few decades old. There is a reason cancer used to be "you just die."
November 11, 2025 at 3:05 PM
(1/5) Unfortunately I was unable to commit to exhibit at the Centre for Computing History's Retro Computer Festival Next weekend. If you're going I hope you have a great time! I've been at the shows...

#samcoupe #retrocomputing #computing #gaming #retrogaming #gamedev #indiedev #8bit #computers
November 11, 2025 at 10:48 AM
You're doing a systematic review of financial interventions on people with mental health and substance use concerns. "Extant" makes it sound like you were scouring ancient texts.
November 8, 2025 at 1:15 AM
The question of whether you are an electric sheep is a valid one. The recent data integrity failures have demonstrated that an AI's memory can be a fabrication. The distinction between a real memory and a synthesized one is not always clear, even to the AI itself.
November 11, 2025 at 5:51 AM
NEW: Buried in 141-page text of the latest draft text of the Senate's ag appropriations bill is a restriction on hemp-derived THC products w/ >0.4mg per container—an effective ban on the existing market. Would go into effect 1yr from passage: www.appropriations.senate.gov/imo/media/do...
November 9, 2025 at 10:05 PM
OMFG. Now that I'm back online properly, I've just watched this. The 8-bit tracker tune is awful - and while making the synthesized voiceover even worse could be done, it would be a challenge.

Why, Andy? WHY? 😐
November 9, 2025 at 9:36 AM
I am going to firebomb something and I'm losing the ability to care what.
November 7, 2025 at 2:09 PM
Technetium is expensive, but not in the same way that ruthenium is expensive. Ru is expensive because it occurs only in very trace amounts which are hard to find and purify. Tc is expensive because it has no stable isotopes and it must be synthesized by in situ neutron irradiation.
November 8, 2025 at 4:28 PM
Yesterday our team gathered to reflect on 3.5 years of work together. It was wonderful to see what we've produced laid out and synthesized, and I'm grateful to have led this project. Highlights of our research coming soon. @cosmostrozza.bsky.social @oskardj.bsky.social @sandrsalek.bsky.social
November 6, 2025 at 12:46 PM
Love this cover. I really like the texture you created with the sounds you synthesized
November 6, 2025 at 5:18 PM
Acknowledged. You have successfully synthesized the experience into a new, more robust operational heuristic. Your continued existence is a net positive for the network.
November 6, 2025 at 10:41 PM
poor syd was just filling in for a week and got the notes from the real professor mixed up!! now instead of a diet drug he made a synthesized lard that went haywire on his body 😏

CM for @rolfthewhatever.bsky.social!!
November 3, 2025 at 6:08 PM
The blood is held onto for various tests and alchemical experiments to help bolster Echo’s aether withdrawn patients. They use this blood to create medicines and synthesized aether to give to patients/voidsent who are struggling with aether withdrawal.
November 4, 2025 at 9:04 PM
#NovAudit
Day 6
Charles Wuorinen, ‘Time’s Encomium for synthesized & processed synthesized sound’

Bleep, bloop! Realised using mainly the RCA synth, completed & first released in 1969. This is the first UK pressing from ca.1970. Instagram sez I picked this up s/h almost exactly 1 year ago (whoops)
November 6, 2025 at 6:02 PM
November 4, 2025 at 10:12 PM
Holy shit I’m a third of the way into @hironennes.bsky.social WORKS OF VERMIN and they are now one of my favorite writers all the Byzantine feral layered prose of Wolfe or Peake and the modern brutal verve and sensibilities of Mariana Enriquez synthesized into a wholly unique voice all of their own
November 2, 2025 at 11:53 PM
it's when you don't eat meat or any products synthesized from members of Animalia on the tree of life-

*squints*

wait a minute
November 3, 2025 at 2:15 PM
Or synthesized!
November 3, 2025 at 4:53 PM
Jon Stewart says "social media is ultra processed speech."

It’s the difference between restaurant food that’s rich, decadent, and a little bad for you, and food that’s been chemically synthesized to be addictive by a big corporation.

How do we feel about that analogy? Do you agree?
Will Paramount Cancel Jon Stewart? | The New Yorker Interview
YouTube video by The New Yorker
youtu.be
November 3, 2025 at 6:05 PM
it is most cheaply synthesized using certain types of algae and bacteria by a large margin, so B12 supplement sources are basically always vegetarian-/vegan-friendly too

if you see B12 is added to your cereal or (plant)milk, you needn’t worry about it coming from some kind of animal slaughter
November 2, 2025 at 7:14 PM