#ParietalCortex
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plosbiology.org
What are the neural mechanisms behind short-term #memory errors? This study shows that they are primarily linked to a drift in neural activity in posterior #ParietalCortex, highlighting a need for stable neural representations to support accurate memory performance @plosbiology.org 🧪 plos.io/4p85IzD
Ca2+ responses of PPC neurons during a short-term memory task. Left: The schematic illustrates the behavioral task designed to assess short-term memory in head-restrained mice. During the sample phase, black-and-white phase-reversing gratings moved either leftward or rightward (or downward or rightward) for 4 s on a screen in front of the mouse. After a 1.5- or 2-s delay, two laterally positioned lick ports were placed within reach of the mouse’s tongue. Correct licking at the corresponding lick port was rewarded with water, whereas incorrect licking resulted in a time-out as a punishment. Right: Color-coded trial-averaged ΔF/F traces of direction- and phase-selective neurons. Left Panel: neurons selective for rightward stimuli; Right Panel: neurons selective for leftward stimuli. ΔF/F values were normalized to the maximum ΔF/F and aligned based on each neuron’s time-to-peak response. Within each directional group, neurons are subdivided by phase selectivity based on GLM classification: those selective for the sample (S), delay (D), or both phases. The bottom panels display neurons that were jointly selective for both sample and delay phases (86 for rightward, 49 for leftward).
September 5, 2025 at 1:22 PM
nicolashubacz.bsky.social
🧠 The Parietal Cortex

Integrates sensory input for spatial mapping, body awareness, math & logic. Critical for navigation, perception, and coordinated action.

Damage can cause neglect or Gerstmann’s Syndrome.

Credit: Greg A Dunn

#Neuroscience #CognitiveScience #ParietalCortex
September 18, 2025 at 4:48 PM
plosbiology.org
How does sensory information construct representations in the human brain? This study shows that a network including prefrontal & posterior #ParietalCortex & anterior #insula has a key role in translating perceptual information to concepts, semantics & action plans 🧪 @plosbiology.org plos.io/4lbXN2b
Stimuli used for the experimental task. Complete, recognizable examples of object categories and morphed, unrecognizable versions of the same images (cupcake, zucchini, pliers, paint brush, car, cement mixer, heron, skunk). In Experiment 1, the stimuli set was composed of 40 complete images in each of the four categories. In Experiment 2, a subset of 30 complete images per category was employed. All images presented in this figure are included in the BOSS image database and written permission to employ these images in this figure has been kindly granted by the owner.
March 31, 2025 at 1:46 PM
plosbiology.org
What are the neural mechanisms behind short-term #memory errors? This study shows that they are primarily linked to a drift in neural activity in posterior #ParietalCortex, highlighting a need for stable neural representations to support accurate memory performance @plosbiology.org 🧪 plos.io/4p85IzD
Ca2+ responses of PPC neurons during a short-term memory task. Left: The schematic illustrates the behavioral task designed to assess short-term memory in head-restrained mice. During the sample phase, black-and-white phase-reversing gratings moved either leftward or rightward (or downward or rightward) for 4 s on a screen in front of the mouse. After a 1.5- or 2-s delay, two laterally positioned lick ports were placed within reach of the mouse’s tongue. Correct licking at the corresponding lick port was rewarded with water, whereas incorrect licking resulted in a time-out as a punishment. Right: Color-coded trial-averaged ΔF/F traces of direction- and phase-selective neurons. Left Panel: neurons selective for rightward stimuli; Right Panel: neurons selective for leftward stimuli. ΔF/F values were normalized to the maximum ΔF/F and aligned based on each neuron’s time-to-peak response. Within each directional group, neurons are subdivided by phase selectivity based on GLM classification: those selective for the sample (S), delay (D), or both phases. The bottom panels display neurons that were jointly selective for both sample and delay phases (86 for rightward, 49 for leftward).
September 5, 2025 at 8:02 AM
plosbiology.org
What are the neural mechanisms behind short-term #memory errors? This study shows that they are primarily linked to a drift in neural activity in posterior #ParietalCortex, highlighting a need for stable neural representations to support accurate memory performance @plosbiology.org 🧪 plos.io/4p85IzD
Ca2+ responses of PPC neurons during a short-term memory task. Left: The schematic illustrates the behavioral task designed to assess short-term memory in head-restrained mice. During the sample phase, black-and-white phase-reversing gratings moved either leftward or rightward (or downward or rightward) for 4 s on a screen in front of the mouse. After a 1.5- or 2-s delay, two laterally positioned lick ports were placed within reach of the mouse’s tongue. Correct licking at the corresponding lick port was rewarded with water, whereas incorrect licking resulted in a time-out as a punishment. Right: Color-coded trial-averaged ΔF/F traces of direction- and phase-selective neurons. Left Panel: neurons selective for rightward stimuli; Right Panel: neurons selective for leftward stimuli. ΔF/F values were normalized to the maximum ΔF/F and aligned based on each neuron’s time-to-peak response. Within each directional group, neurons are subdivided by phase selectivity based on GLM classification: those selective for the sample (S), delay (D), or both phases. The bottom panels display neurons that were jointly selective for both sample and delay phases (86 for rightward, 49 for leftward).
September 4, 2025 at 4:35 PM
plosbiology.org
How does sensory information construct representations in the human brain? This study shows that a network including prefrontal & posterior #ParietalCortex & anterior #insula has a key role in translating perceptual information to concepts, semantics & action plans 🧪 @plosbiology.org plos.io/4lbXN2b
Stimuli used for the experimental task. Complete, recognizable examples of object categories and morphed, unrecognizable versions of the same images (cupcake, zucchini, pliers, paint brush, car, cement mixer, heron, skunk). In Experiment 1, the stimuli set was composed of 40 complete images in each of the four categories. In Experiment 2, a subset of 30 complete images per category was employed. All images presented in this figure are included in the BOSS image database and written permission to employ these images in this figure has been kindly granted by the owner.
March 31, 2025 at 8:28 AM
plosbiology.org
How does sensory information construct representations in the human brain? This study shows that a network including prefrontal & posterior #ParietalCortex & anterior #insula has a key role in translating perceptual information to concepts, semantics & action plans 🧪 @plosbiology.org plos.io/4lbXN2b
Stimuli used for the experimental task. Complete, recognizable examples of object categories and morphed, unrecognizable versions of the same images (cupcake, zucchini, pliers, paint brush, car, cement mixer, heron, skunk). In Experiment 1, the stimuli set was composed of 40 complete images in each of the four categories. In Experiment 2, a subset of 30 complete images per category was employed. All images presented in this figure are included in the BOSS image database and written permission to employ these images in this figure has been kindly granted by the owner.
March 31, 2025 at 5:45 PM