Lipid quality control #Ferroptosis

"Lipid Droplet-localized FSP1/ferroptosis suppressor protein 1 reduces CoQ10 to generate local antioxidants that prevent neutral lipid peroxidation"

Any role of FSP1 in #Atherosclerosis!?😆

@olzmannlab.bsky.social #NatCellBio 2025
www.nature.com/articles/s41...

🤔 #mDia also associates with #microtubules.... (Gundersen team in NatCellBio 2001). @microtubule.bsky.social & I pondered over the #FocalAdhesion splitting & merging phenotype we saw with CLASP-depletion for ages. Great to see someone worked out how to quantitate it!
www.science.org/doi/10.1126/...

Type R capillary #EndothelialCell in Bone
Cav1+ Efnb2+Flt4-Emcn+
B/w Sinusoid EC & Artery
👉Close to trabecular🦴 osteoprogenitor osteoclast
👉Angiocrine SEMA7A+

⏫by #Aging anti-osteoporosis therapy

@vishalmkrishnan.bsky.social l @ralfhadams.bsky.social #NatCellBio 2024
www.nature.com/articles/s41...

The presence of extraembryonic cells in the developing gut has long puzzled scientists. In a new study in NatCellBio, the Meissner lab unravels the fate and molecular characteristics of these cells.
Read more: www.molgen.mpg.de/4717564/
Link to publication: www.nature.com/articles/s41...