#MesoSPIM
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ijpb-versaillescly.bsky.social
🔬 Afternoon workshops at #IJPB covered a wide range of cutting-edge imaging techniques: FLIM & STED, microfluidics, expansion microscopy, pH biosensors, laser microdissection, Mesospim, and more! #RMUI

@inrae-france.bsky.social
November 6, 2025 at 4:56 PM
biorxivpreprint.bsky.social
Mechanical de-skewing enables high-resolution imaging of thin tissue slices with a mesoSPIM light-sheet microscope https://www.biorxiv.org/content/10.1101/2025.10.29.684106v1
October 30, 2025 at 8:57 PM
biorxiv-biophys.bsky.social
Mechanical de-skewing enables high-resolution imaging of thin tissue slices with a mesoSPIM light-sheet microscope https://www.biorxiv.org/content/10.1101/2025.10.29.684106v1
October 30, 2025 at 8:57 PM
brandy-syglass.bsky.social
It was actually the first mesoSPIM dataset I ever rendered and I’ve been so happy to learn the history of it. Did you go to the anniversary conference this year? Michael made it but I was in Montreal at BINA.
October 23, 2025 at 6:34 PM
michael-syglass.bsky.social
The #mesoSPIM symposium really opened my eyes to the power of open source hardware. I've highlighted some of the surprising outcomes in a new blog post:

How Open Source Microscopy is Solving the Funding Crisis: Insights from the mesoSPIM 10-Year Symposium

www.syglass.io/blog/how-ope...
October 23, 2025 at 4:17 PM
brandy-syglass.bsky.social
The #mesoSPIM community just celebrated 10 years of open-source light-sheet microscopy in Zürich! For #3DThursday, we're honoring Martina Schaettin & Fabian Voigt’s iconic 3D chick embryo dataset — a luminous benchmark for open science and shared discovery.
#Microscopy #Lightsheet #syGlass
October 23, 2025 at 3:33 PM
michael-syglass.bsky.social
I have really neglected Bluesky. I'm going to try to add my backlog of adventures here now. To start, #mesoSPIM symposium in Zurich! Amazing conference, amazing people, amazing talks!
October 23, 2025 at 9:39 AM
moritz-negwer.mstdn.science.ap.brid.gy
This week I had the pleasure of attending the hashtag#MesoSPIM Symposium in Zürich, Switzerland - and what an experience it's been! Top-notch presentations, great posters and great chats with my fellow #lightsheet #microscopy and #tissueclearing nerds. You know […]

[Original post on mstdn.science]
Moritz in front of his poster presentation at the MesoSPIM Symposium in Zürich, Switzerland Me in front of the ÖBB Nightjet sleeper train carriage that took me to Zürich and back. Surprisingly comfortable if you book the sleeper wagon with the nice beds!
October 19, 2025 at 6:56 PM
lbaudis.bsky.social
Beautiful day in Zurich for the start of the 10 Years of mesoSPIM workshop at the Careum this morning: www.ema.uzh.ch/en/register/... - organised by @mesospim.bsky.social
The mesoSPIM 10-year Symposium
Day 1: Monday, October 13-th , Day 2: Tuesday, October 14-th, Day 3: Wednesday, October 15-th | Careum Auditorium
www.ema.uzh.ch
October 13, 2025 at 8:09 AM
ierp-inrae.bsky.social
🚀 Nouvelle étape pour #MesoSPIM !
Après avoir monté le microscope à l'IERP de l'INRAE Jouy-en-Josas avec des physiciens de l'ENS Paris-Saclay 🤝, il devient transportable 🧳.

Rendez-vous à #MiFoBio & #JST_RmuI pour le découvrir en vrai 🔬✨

@inrae-france.bsky.social @gdrimabio.bsky.social
October 3, 2025 at 1:58 PM
mdibl.org
Thanks go out to MDI Bio Lab Digital Image Analyst @hsomers.bsky.social for this #microscopymonday view of an adult #zebrafish (brain vasculature) from the MesoSPIM.

#standwithscience #researchmatters 🧪 🤝 🐟🎸 #microscopy #fluorescentproteins #lightsheet
September 22, 2025 at 12:20 PM
mesospim.bsky.social
Both are experienced clinical pathologists who are master users of #mesoSPIM and developed their own way of staining and clearing the most challenging tissues in their clinical practice. Want to learn which method will work best with your samples? Join us at #mesoSPIM2025 t.uzh.ch/1Ss
3/3
Registration
t.uzh.ch
August 27, 2025 at 10:32 AM
mesospim.bsky.social
Is it possible to stain specific proteins and cell types in old formalin-fixed human tissues and make them transparent for light-sheet imaging and clinical 3D diagnostics?

🧵 1/3
Image presenting two of the speakers for the 10 Years of mesoSPIM symposium. Background of the image is a microscopy picture showing blood vessels in magenta and glial cells in cyan on a black field. On the top left, the photo of the first speaker is contained in a white-rimmed circle. On the top right the text reads: "Hei Ming Lai, The Chinese University of Hong Kong, HK" followed by the talk title "Customizing mesoSPIM-based workflows for clinical 3D tissue Diagnostics". On the lower part of the image, the second speaker is presented in a specular manner. On the lower left, text reads “Anna Maria Reuss, University Hospital, Zurich, Switzerland”, followed by the talk title “aDISCO - A Broadly Applicable Method for 3D Microscopy of Archival Paraffin-Embedded Human Tissues”. On the lower left, the photo of the second speaker is contained in a white-rimmed circle. On the bottom right it reads “10 Years of mesoSPIM Symposium”
August 27, 2025 at 10:32 AM
voigtvision.bsky.social
One of the people I'm indebted the most for creating stunningly beautiful #mesoSPIM samples was Martina Schaettin - who tragically passed away in March this year. To honor her memory, Elkhan Yusifov created an award - submit your best #microscopy images & videos! www.linkedin.com/company/mart...
August 22, 2025 at 5:32 PM
voigtvision.bsky.social
Thanks to @nvladimus.bsky.social the @mesospim.bsky.social #lightsheet #Microscope community is now on forum.image.sc/tag/mesospim !
mesospim.bsky.social mesoSPIM: Clear Images. Big samples. Open source. @mesospim.bsky.social · Aug 22
📣We have opened our official User Forum: forum.image.sc/tag/mesospim
In this forum you can connect with 🔬developers and the image analysis experts. Ask your burning questions about the #mesoSPIM hardware, software, and image processing, or help the beginners to get started!
Tip: use project tags!
Topics tagged mesospim
Topics tagged mesospim
forum.image.sc
August 22, 2025 at 3:58 PM
mesospim.bsky.social
📣We have opened our official User Forum: forum.image.sc/tag/mesospim
In this forum you can connect with 🔬developers and the image analysis experts. Ask your burning questions about the #mesoSPIM hardware, software, and image processing, or help the beginners to get started!
Tip: use project tags!
Topics tagged mesospim
Topics tagged mesospim
forum.image.sc
August 22, 2025 at 8:04 AM
mesospim.bsky.social
How to image across scales from organs to synapses, unravel biological mechanisms and handle massive data?
Learn more from @adamkglaser.bsky.social, senior scientist at the Allen Institute and the lead developer of #ExA-SPIM technique, at the #mesoSPIM2025 Symposium, Oct 13-15.
Image presenting one of the speakers for the 10 Years of mesoSPIM symposium. Background of the image is a microscopy picture showing blood vessels in magenta and glial cells in cyan on a black field. On the left, the photo of the speaker is contained in a white-rimmed circle. On the right the text reads: "Adam Glaser, Allen Institute, WA, USA" followed by the talk title "New technologies for mapping centimeter scale tissues with nanoscale resolution". On the bottom right it reads “10 Years of mesoSPIM Symposium”
August 20, 2025 at 11:38 AM
mesospim.bsky.social
💥How can light-sheet help reveal dark matter?💥
Join Prof. Laura Baudis @lbaudis.bsky.social at #mesoSPIM Symposium, Oct 13–15 in Zurich or online, to see how light-sheet fluorescence microscopy 🔬 is used to image nuclear ☢️ recoil tracks to detect elusive particles!
Register now: t.uzh.ch/1Ss
mage presenting one of the speakers for the 10 Years of mesoSPIM symposium. Background of the image is a microscopy picture showing blood vessels in magenta and glial cells in cyan on a black field. On the left, the photo of the speaker is contained in a white-rimmed circle, on the right text reads: "Laura Baudis, University of Zurich, Switzerland" followed by the talk title "Probing dark matter and neutrinos with light sheet microscopy". On the bottom right reads "10 Years of mesoSPIM Symposium”
August 18, 2025 at 9:28 AM
brandy-syglass.bsky.social
Organoids for #3DThursday! This is a tiny, lab-grown 3D model of a lung, meant to mimic the structure and function of real tissues.

🔬: #mesoSPIM #Lightsheet
🧫: Lung Organoid
🥼: Hei Ming Lai
🏛️: Illumos Ltd, www.nature.com/articles/s41...
🎬: syGlass.io

#SciComm #TissueEngineering #Organoid #syGlass
August 7, 2025 at 9:45 AM
mesospim.bsky.social
🎉 Call for Abstracts! 🎉
Abstract deadline approaching! 10 years of #mesoSPIM initiative – join us at the symposium for talks, demos & posters on microscopy, tissue clearing, and data analysis!
📆 October 13-15, 2025
🗺️ Zurich, Switzerland, but also online.
www.adabd.uzh.ch/en/events/me...
July 3, 2025 at 10:27 AM
mdibl.org
Fabian Voigt — visiting scientist at MDI Bio Lab and ‪@harvard.edu‬ neurobiologist postdoc — helped install our mesoSPIM microscope and is now building tools to track zebrafish brain activity as they swim and interact. Read the Q&A.

#standwithscience #researchmatters 🧪 🤝
A New Lens on Biology
mdibl.org
July 2, 2025 at 4:30 PM
mesospim.bsky.social
🎉 Call for Abstracts! 🎉
We’re celebrating 10 years of #mesoSPIM #opensource initiative – join us at the symposium for talks, demos & posters on open-source light-sheet microscopy, tissue clearing, and imaging!
Dates: October 13-15, 2025
Location: Zurich, Switzerland
Registration: ema.uzh.ch/R7YRN
June 12, 2025 at 9:15 AM
ierp-inrae.bsky.social
🔬 On June 6, we inaugurated the first #MesoSPIM in France at INRAE Jouy-en-Josas & ENS Paris-Saclay! A big thanks to @nvladimus.bsky.social , @mgarbelli.bsky.social ,Angeliki Vavladeli & all speakers and sponsors. Exciting step forward for #opensource imaging & interdisciplinary science! #microscopy
June 10, 2025 at 10:34 AM
mesospim.bsky.social
Did you know that Universite Paris Saclay has its own Benchtop #mesoSPIM? Interdisciplinary team lead by @christellelangevin.bsky.social has built their own setup, the first in France, and organized an inauguration symposium! Cleared baby sturgeon or trout? They have it! French bioimaging is strong!
June 7, 2025 at 11:23 AM
jasonmileskirk.bsky.social
New chamber mount design for our @mesospim.bsky.social - magnetic kinematic bases from @thorlabs.bsky.social for the win! 3D printed (for now) bases hold the chamber snugly for precise positioning between experiments. Fill port on the front allows for media addition without disturbing imaging.
Stainless Imaging chamber for mesoSPIM with 3D printed kinematic mounts
June 3, 2025 at 7:09 PM