#LongNonCodingRNA
Discover the significance of long non-coding RNAs with Novogene’s lncRNA sequencing services. Gain insights into gene regulation and disease mechanisms.

Learn more: bit.ly/3DpuzLZ

#lncRNA #LongNonCodingRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation
June 5, 2025 at 7:39 AM
Discover the significance of long non-coding RNAs with Novogene’s lncRNA sequencing services. Gain insights into gene regulation and disease mechanisms.

Learn more: bit.ly/3DpuzLZ

#lncRNA #LongNonCodingRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation
September 5, 2025 at 7:30 AM
#LongNoncodingRNA #SmoothMuscleCell #Seneascence #Atherosclerosis

LncRNA JPX (just proximal to XIST), in complex with #BRD4 NF-κB, transcriptionally activates #SASP in senescent SMCs

SMC Jpx KO⏬🐭#Atherosclerosis +⏬lesional SMC senescence SASP

#ATVB 2024
www.ahajournals.org/doi/10.1161/...
September 8, 2024 at 7:25 PM
August 8, 2025 at 6:28 PM
#LongNonCodingRNA #Senescence #Atherosclerosis

JPX, a chromosome-associated regulatory RNA, complexes with BRD4 & p65 (NFκB subunit) to mediates 3D chromatin remodeling &⏫transcriptional activation of senescence secretome in #SmoothMuscleCell

#ATVB 2024
www.ahajournals.org/doi/10.1161/...
July 24, 2024 at 11:22 AM
July 25, 2025 at 5:58 PM
#LongNonCodingRNA #SmoothMuscleCell

LncDACH1⏬SMC proliferation+migration & #Neointima of #ArterioVenousFistula, partially via ⏬HSP90 abundance & sequestrating SRPK1 in the nuclei

A similar pro-intimal role in #Atherosclerosis?

#NatureComms 2024
www.nature.com/articles/s41...
May 17, 2024 at 7:50 PM
Discover the significance of long non-coding RNAs with Novogene’s lncRNA sequencing services. Gain insights into gene regulation and disease mechanisms.

Learn more: bit.ly/3DpuzLZ

#lncRNA #LongNonCodingRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation
April 25, 2025 at 7:14 AM
Enhancer-associated #LongNonCodingRNA #Atherosclerosis

PSMB8-AS1⏫promixal gene transcription of PSMB9 in #EndothelialCell->
Zeb1->
VCAM1/ICAM1->
#VascularInflammation #Atherosclerosis

Serum lipids also regulated by PSMB8-AS1

#CircRes 2023
www.ahajournals.org/doi/10.1161/...
December 19, 2023 at 7:31 PM
The emerging roles of long non-coding RNAs in the nervous system. #LongNonCodingRNA #NervousSystem #Genomics @natrevneuro.nature.com 🧬
www.nature.com/articles/s41...
September 6, 2025 at 7:32 AM
The LINC01612-DVL2-WNT regulatory axis promotes human endoderm differentiation – a key modulator of human definitive endoderm differentiation. #longnoncodingRNA #DVL2 #WNT #endoderm https://ow.ly/zvgJ50XhLB8

ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation
October 29, 2025 at 1:35 PM
August 1, 2025 at 5:15 PM
#LongNonCodingRNA #LncRNA transcriptomics Lower-extremity #PeripheralArteryDisease -/+ T2D #Diabetes

Iliac artery n=79
T2D->⏬ACTA2-AS1

#SmoothMuscleCell microdissected from FFPE section
T2D->⏫LINC00910/RUFY1-AS1 ⏬HIF1A-AS3/XIST!/NEAT1/MIR222HG

#SciReports 2024
www.nature.com/articles/s41...
July 20, 2024 at 7:22 PM